Ollscoil na hÉireann, Gaillimh GX_____
National University of Ireland, Galway
Semester I Examinations 2007 / 2008
Exam Code(s) 2BS1, 2BO1, 2BY1
Exam(s) 2nd Science
Module Code(s) BI204
Module(s) Biomolecules in the Cell
Repeat Paper Yes
External Examiner(s) Dr. Paul McLaughlin
Internal Examiner(s) Dr. L. Byrnes, Dr. J. Donlon, Dr. L. O’Connor,
Dr. J. O’Keeffe, Dr. M. Tuohy.
Instructions: Section A (25 marks)
Answer all questions. In all questions there is only ONE correct
answer. Record your answers on the OPTICAL READER
Section B, C, D and E (25 marks/ question: 20 marks for part A
of each question and 5 marks for part B)
Answer 3 questions, one only from each section.
Answer questions from each section on a SEPARATE answer
Duration 3 hours
No. of Pages 12
Course Co-ordinator(s) Dr. Lynn O’Connor
Other Material MCQ optical reader sheet
Answer all questions in Section A
All questions carry equal marks
Section A is equal to 25 marks
In all questions there is only ONE correct answer
Do not write answers on this sheet. USE OPTICAL READER SHEETS ONLY
1. What organic compound is illustrated below
A) an alcohol
B) a aldehyde
C) a ketone
D) a carboxylic acid
2. What organic compound is illustrated below
A) a thiol
B) a primary amine
C) an aldehyde
D) a ketone
3. Identify the organic compound illustrated below
A) a primary amine
B) a secondary amine
C) a tertiary amine
D) a quaternary amine
4. Identify the functional group illustrated below
5. Identify the functional group illustrated below
B) phosphate ester
6. Identify the linkage illustrated below
7. Identify the linkage illustrated below
A) phosphate ester
8. In a typical eukaryotic cell the pH is usually around 7.4. What is the [H+] in
a typical eukaryotic cell?
A) 0.000000074 M
B) 4 X 10-8 M
C) 7.4 X 10-5 M
D) 2.3 nM
9. Water derives all its special properties from its:
A) cohesiveness and adhesiveness
B) high boiling point and melting point
C) polarity and hydrogen-bonding capacity
D) small degree of ionization
10. A moon on Jupiter was recently shown to have a weather system of liquid
methane but there is no water. Any life that might exist on this moon would
be unlike that on earth because:
A) water is a solvent for many biomolecules
B) water is a chemical participant in many biological reactions
C) water’s attraction to itself drives hydrophobic interactions
D) all of the above are true
11. Which of the following is true of hydrogen bonds?
A) The attraction between the oxygen atom of a water molecule and the hydrogen
atom of another molecule constitutes a hydrogen bond
B) Hydrogen bonds form as covalent bonds between positively and negatively
C) Hydrogen bonds form between nonpolar portions of biomolecules
D) A and B are true
12. Which statement is true about a reaction with an equilibrium constant, Keq,
equal to 1000?
A) the forward rate constant is 3 times greater than the reverse rate constant
B) The forward rate constant is 1000 times greater than the reverse rate constant
C) The forward rate constant is 1000 times smaller than the reverse rate constant
D) The forward rate constant is 3 times smaller than the reverse rate constant
13. If it takes approximately 20kJ.mole-1to break a hydrogen bond in water,
approximately what energy value is required to break a covalent O-H bond?
A) 10kJ.mole-1 B) 100kJ.mole-1 C) 200kJ.mole-1 D) 450kJ.mole-1
14.In DNA, phosphodiester bonds form with hydroxyl groups of carbons
number ________ and ________ of each deoxyribose sugar.
A) 2'; 3' B) 2'; 4' C) 3'; 4' D) 3'; 5' E) 4'; 5'
15. The difference between dGMP and GMP is
A) the type of phosphodiester linkage. B) one hydroxyl group.
C) syn versus anti conformation. D) the occurrence in DNA or RNA.
16. The tetranucleotide AGTC (in DNA) has a free hydroxyl group on
A) A. B) A, G, T, and C. C) C. D) G, T, and C.
17. It is easier to melt DNA richer in AT than GC because
A) AT are smaller than GC
B) there is one less hydrogen bond.
C) the helix pitch is longer in AT rich regions.
D) All of the above