Gastrointestinal Pathophysiology 5-Pathophysiology-Lab Assignment, Exercises of Pathophysiology

Download Gastrointestinal Pathophysiology 5-Pathophysiology-Lab Assignment and more Exercises Pathophysiology in PDF only on Docsity! Gastrointestinal Pathophysiology (HST-121) Laboratory Assignment #3 (Due Friday, November 18th) NAME: Recommended reading: 1. Lecture notes on Lipid Digestion, Mucosal Immunology, Motility, and Neoplasms In a "classical" case of ulcerative colitis, which of the following features are present: ⎯ Granulomas ⎯ Fissuring ulcers ⎯ Fistulas ⎯ Mural thickening and fibrosis ⎯ Creeping fat ⎯ Bloody diarrhea ⎯ Strictures ⎯ Dilatation ⎯ "Skip" areas ⎯ Perianal disease such as fissures and tags Decide if each of the following statements is true or false? ⎯ Polymeric Ig receptor (pIgR) is initially targeted to the basolateral surface of enterocytes. ⎯ Intraepithelial lymphocytes (IELs) are an equal mixture of T and B cells. ⎯ IELs are predominantly CD45RO positive, suggesting that they are memory cells. ⎯ If activated, IELs can function as cytolytic effector cells. ⎯ Celiac sprue results in iron-deficiency because of a molecular defect in proteins involved in transepithelial iron transport. ⎯ Compared with UC, Crohn's disease is associated with a higher risk of adenocarcinoma. ⎯ Angiodysplasia is a term commonly used to refer to Hereditary Hemorrhagic Telangietasia. ⎯ Gastric lipase breaks triglycerides into diglycerides and fatty acids. ⎯ Pancreatic lipase breaks triglycerides into monoglycerides and fatty acids. ⎯ Achalasia is lower esophageal obstruction due to a mass-occupying lesion. - 1 - assignment 3 docsity.com