Solvent, Leaving Group, Bridgehead Substitution, and Pentavalent Carbon - Freshman Organic Chemistry - Michael McBride - Lecture 8 of 38 - Video-lecture

Video-lecture, Organic Chemistry

Description: The nature of nucleophiles and leaving groups has strong influence on the rate of SN2 reactions. Generally a good nucleophile or strong base is a poor leaving group, but hydrogen-bonding solvents can alter nucleophile reactivity.