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ANESTHESIA PHARMACOLOGY EXAM 2024-2025 LATEST UPDATED QUESTIONS WITH CORRECT VERIFIED ANSW, Exams of Nursing

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ANESTHESIA PHARMACOLOGY EXAM 2024-

LATEST UPDATED QUESTIONS WITH CORRECT

VERIFIED ANSWERS GRADED A+.

Xenon anesthesia all are true except:

  1. Slow induction and recovery
  2. Non explosive
  3. Minimal cardiovascular side-effects
  4. Low blood solubility 12/e p547-548 - Solution 1) Slow induction and recovery Anesthetic having epileptogenic potential is:
  5. Desflurane
  6. Sevoflurane
  7. Ether
  8. Halothane 11/e p432 - Solution 2) Sevoflurane The following causes increased intra ocular pressure:
  9. Thiopentone
  10. Althesin
  11. Ketamine
  12. Barbiturate Goodman and Gilman 12/e p538 - Solution Anaesthesia contraindicated in volvulus of gut is:
  13. Halothane
  14. Nitrous oxide
  15. Ketamine
  16. Pancuronium Goodman and Gilman 12/e p547 - Solution 2) Nitrous oxide Best uterine relaxation is seen with:
  17. Chloroform
  1. Nitrous oxide
  2. Ether
  3. Halothane 10/e p405; KDT 6/e p372 - Solution 4) Halothane Hallucinations are seen after ............... anaesthesia:
  4. Ketamine
  5. Thiopentone
  6. Fentanyl
  7. Nitrous oxide 10/e p409; KDT 6/e p376 - Solution 1) Ketamine Anaesthetic that has a smooth induction is:
  8. Diethyl ether
  9. Isoflurane
  10. N
  11. Halothane 10/e p404; KDT 6/e p372 - Solution 4) Halothane MAC of desflurane is:
  12. 2
  13. 4
  14. 6 744; KDT 6/e p371 - Solution 4) 6 Remifentanil is:
  15. Useful for short painful procedures
  16. Metabolized by plasma esterases
  17. Equipotent as fentanyl
  18. All of these Good¬man and Gilman 11/e p572 - Solution 4) All of these Select the correct statement about nitrous oxide:
  19. It irritates the respiratory mucosa
  20. It has poor analgesic action
  1. It is primarily used as a carrier and adjuvant to other anaesthetics
  2. It frequently induces post anaesthetic nausea and retching KDT 6/e p371 - Solution 3) It is primarily used as a carrier and adjuvant to other anaesthetics Remember: Nitrous oxide is a good analgesic. Dissociative anaesthesia' is produced by:
  3. Ketamine
  4. Fentanyl
  5. Propofol
  6. Both (a) and (b) are correct KDT 6/e p376 - Solution 1) Ketamine Ketamine should be avoided in:
  7. The presence of increased arterial pressure
  8. Pregnancy
  9. Hypovolemic shock
  10. Asthmatic /e p437 - Solution 1) The presence of increased arterial pressure The drug for OPD analgesia is:
  11. Morphine
  12. Pethidine
  13. Fentanyl
  14. Alfentanil 11/e p546 - Solution 4) Alfentanil True statement about sevoflurane is:
  15. It is nephrotoxic at high doses
  16. It has maximum risk of causing convulsions
  17. It is cardiostable
  18. It can cause fulminant hepatitis Goodman & Gilman 11/e p360; KDT 6/e p74 - Solution 1) It is nephrotoxic at high doses Which of the following does not have analgesic action:
  1. Ether
  2. Ketamine
  3. Halothane
  4. Morphine 6/e p372 - Solution 3) Halothane Halothane-No analgesia Nitrous oxide-- Good analgesia Induction agent of choice in day care surgery is:
  5. Ketamine
  6. Propofol
  7. Methohexitone
  8. Thiopentone sodium 6/e p375 - Solution 2) Propofol True statements regarding halothane is:
  9. Hepatitis occurs in susceptible individuals after repeated dose
  10. It potentiates competitive neuromuscular blockers
  11. Causes respiratory depression
  12. All of the above /e p432,461 - Solution 4) All of the above In raised ICT, anesthetic agent of choice is:
  13. Enflurane
  14. Isoflurane
  15. Ketamine
  16. Ether 6/e p373 - Solution 2) Isoflurane ## Which anesthetic agent is contraindicated in epilepsy?
  17. Isoflurane
  18. Enflurane
  19. Halothane
  20. Ether 6/e p372 - Solution 2) Enflurane In patients with liver disease, anesthetic of choice is:
  1. Halothane
  2. Ether
  3. Isoflurane
  4. None 6/e p373 - Solution 3) Isoflurane Dissociative anesthesia is seen on administration of:
  5. Ether
  6. Halothane
  7. Enflurane
  8. Ketamine 6/e p376 - Solution 4) Ketamine Thiopental sodium is administered intravenously as:
  9. 25% solution
  10. 2.5% solution
  11. 0.25% solution
  12. 0.025% solution Morgan 4/e p187 - Solution 2) 2.5% solution The recommended time for prophylactic antibiotic is:
  13. 30 min. prior to induction of anesthesia
  14. 15 min. after the initiation of surgery
  15. At the time of induction
  16. At the time of skin incision /e p898 - Solution 1) 30 min. prior to induction of anesthesia Methemoglobinemia is caused by:
  17. Prilocaine
  18. Ropivacaine
  19. Bupivacaine
  20. Procaine /e p449 - Solution 1) Prilocaine First local anesthetic used in clinical anaesthesia was:
  21. Bupivacaine
  22. Procaine
  23. Lidocaine
  1. Cocaine Ajay Yadav 3/e p105 - Solution 4) Cocaine In spinal anaesthesia the drug is deposited between:
  2. Dura and arachnoid
  3. Pia and arachnoid
  4. Dura and vertebra
  5. Into the cord substance Katzung 10/e p419; KDT 6/e p359 - Solution 2) Pia and arachnoid Bupivacaine poisoning is treated with:
  6. Esmolol
  7. Sotalol
  8. Diazepam
  9. All of these Ajay yadav 2/e p110 - Solution 4) All of these The segmental level of spinal anaesthesia depends on:
  10. Volume of the local anaesthetic injected
  11. Specific gravity of the local anaesthetic solution
  12. Posture of the patient
  13. All of the above 6/e p359, 360 - Solution 4) All of the above In spinal anaesthesia the segmental level of:
  14. Sympathetic block is lower than the sensory block
  15. Sympathetic block is higher than the sensory block
  16. Motor block is higher than the sensory block
  17. Sympathetic, motor and sensory block has the same level 6/e p360 - Solution 2) Sympathetic block is higher than the sensory block Intravenous regional anaesthesia is suitable for:
  18. Orthopedic manipulation on the upper limb
  19. Vascular surgery on the lower limb
  20. Head and neck surgery
  21. Caesarian section 6/e p361 - Solution 1) Orthopedic manipulation on the upper limb

Most cardiotoxic local anaesthetic is:

  1. Procaine
  2. Bupivacaine
  3. Prilocaine
  4. Tetracaine 6/e p357, 358 - Solution 2) Bupivacaine All are vasodilators except:
  5. Procaine
  6. Lidocaine
  7. Cocaine
  8. Chlorprocaine /e p448 - Solution 3) Cocaine The following statements about Bupivacaine are true except:
  9. Must never be injected into a vein
  10. More cardiotoxic than lignocaine
  11. 0.5 percent is effective for sensory block
  12. It produces methaemoglobinemia /e p448-450 - Solution 4) It produces methaemoglobinemia All are true about bupivacaine Except:
  13. Less cardiotoxic than lignocaine
  14. Dose increases with adrenaline
  15. Long acting
  16. Cannot be given in vein 6/e p357 - Solution 1) Less cardiotoxic than lignocaine Local anesthetics act by:
  17. Affecting at the spinal level
  18. Affecting the Na+ channels
  19. Affecting the K+channels
  20. Blocking axonal transport 6/e p353 - Solution 2) Affecting the Na+ channels

Local anesthetics:

  1. Block the release of neurotransmitters
  2. Block the influx of sodium into the cell
  3. Increase the release of inhibitory neurotransmitters
  4. Inhibit the efflux of sodium from neurons 6/e p353 - Solution 2) Block the influx of sodium into the cell Post dural (Spinal) puncture headache is due to:
  5. Seepage of CSF
  6. Fine needle
  7. Toxic effects of the drugs
  8. Traumatic damage to nerve roots 6/e p360 - Solution 1) Seepage of CSF True statement regarding Bupivacaine is:
  9. Used intravenously along with lignocaine
  10. More cardiotoxic than lignocaine
  11. Contraindicated in pregnancy
  12. All of the above /e p448 - Solution 2) More cardiotoxic than lignocaine Percentage of lignocaine used in spinal anesthesia is:
  13. 0.5%
  14. 1%
  15. 2%
  16. 5% 7/e p368 - Solution The most potent and longest acting anaesthetic agent is:
  17. Dibucaine
  18. Tetracaine
  19. Bupivacaine
  20. Lignocaine 6/e p358 - Solution 1) Dibucaine Central muscle relaxants act by:
  21. Decreasing nerve conduction
  1. Inhibiting spinal polysynaptic reflexes
  2. Blocking conduction across NM junction
  3. Causing CNS depression
  4. Decreasing muscle excitation 6/e p348 - Solution 2) Inhibiting spinal polysynaptic reflexes Cis-atracurium is preferred over atracurium, because:
  5. It has rapid onset of action
  6. It causes less release of histamine
  7. It has short duration of action
  8. It has less depressant action on heart Miller's 7/e p869 - Solution 2) It causes less release of histamine Laudanosine is a metabolite of:
  9. Atracurium
  10. Cis-atracurium
  11. Pancuronium
  12. Vecuronium Miller 7/e p880 - Solution 1) Atracurium Muscle relaxant of choice in liver disease is?
  13. Atracurium
  14. Pipecuronium
  15. Rocuronium
  16. Vecuronium /e p456 - Solution 1) Atracurium Which of the following is a metabolite of carisoprodol?
  17. Doxylamine
  18. Meprobromate
  19. Dimethadione
  20. Amphetamine Goodman and Gilman 11/e p422 - Solution 2) Meprobromate All of the following can aggravate Myasthenia gravis except:
  21. Azathioprine
  22. d- Tubocurarine
  1. Tetracycline
  2. Aminoglycoside Harrison 17/e p2677, Ajay yadav 2/e p94 - Solution Shortest acting non-depolarizing muscle relaxant is:
  3. Succinyl choline
  4. Rapacuronium
  5. Atracurium
  6. Pancuronium Miller's anaesthesia 5/e p892; Drugs and equipment in Anaesthesia 5/e p78 Arun Kumar Paul - Solution d-Tubocurarine acts by:
  7. Inhibiting nicotinic receptors at myoneural junction
  8. Inhibiting nicotinic receptors at autonomic ganglion
  9. Producing depolarizing block
  10. By inhibiting reuptake of acetylcholine Katzung 10/e p429; KDT 6/e p342 - Solution 1) Inhibiting nicotinic receptors at myoneural junction Muscle relaxant of choice in renal and hepatic failure is:
  11. Cis-atracurium
  12. Vecuronium
  13. Rocuronium
  14. Rapacuronium Katzung 9/e p432;KDT 6/e p345 - Solution 1) Cis-atracurium Bradycardia is common after injection of:
  15. Midazolam
  16. Succinylcholine
  17. Dopamine
  18. Isoprenaline 6/e p343, 344 - Solution 2) Succinylcholine Pancuronium differs from tubocurarine in that:
  19. It is a depolarizing blocker
  1. Its action is not reversed by neostigmine
  2. It can cause rise in BP on rapid.I.V. injection
  3. It causes marked histamine release 6/e p343, 344 - Solution 3) It can cause rise in BP on rapid.I.V. injection Dantrolene sodium reduces skeletal muscle tone by:
  4. Reducing acetylcholine release from motor nerve endings
  5. Suppressing spinal polysynaptic reflexes
  6. Inhibiting the generation of muscle action potential
  7. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre 6/e p721, 722 - Solution The enzyme pseudocholinesterase acts on:
  8. Decamethonium
  9. Tubocurarine
  10. Gallamine
  11. Suxamethonium /e p454 - Solution 4) Suxamethonium Hoffman's elimination is seen with:
  12. Atracurium
  13. Vecuronium
  14. Pancuronium
  15. Rocuronium /e p454 - Solution 1) Atracurium Non-depolarizing blockade is potentiated by:
  16. Hyperkalemia
  17. Hypomagnesemia
  18. Chronic phenytoin therapy
  19. Quinidine 6/e p345 - Solution 4) Quinidine The drug causing curare like effect are all, EXCEPT:
  20. Chloramphenicol
  21. Polymyxin
  22. Tetracycline
  1. Streptomycin Clinical Anesthesiology by Murray and Morgaii/189;KDT 6/e p346 - Solution 1) Chloramphenicol Suxamethonium is:
  2. Non depolarizing muscle relaxant
  3. Depolarising muscle relaxant
  4. Direct acting muscle relaxant
  5. All of the above 5/e p345 - Solution Baclofen is:
  6. Centrally acting muscle relaxant
  7. Peripherally acting muscle relaxant
  8. Both centrally and peripherally acting muscle relaxant
  9. Direct acting muscle relaxant 6/e p339 - Solution Shortest acting neuromuscular blocker is:
  10. Gallamine
  11. Pancuronium
  12. Succinylcholine
  13. d-TC /e p457 - Solution 3) Succinylcholine Long acting non-depolarizing muscle relaxants is:
  14. Succinylcholine
  15. Mivacurium
  16. Pancuronium
  17. Phenyleplirine 6/e p343 - Solution 3) Pancuronium Mivacurium is short acting drug. In case of spasticity, the drug not used is:
  18. Diazepam
  1. Baclofen
  2. Tizanidine
  3. Amitryptiline 6/e p343 - Solution 4) Amitryptiline The following is the feature of depolarizing blockade?
  4. Tetanic fade
  5. Post tetanic potentiation
  6. Progression to dual blockade
  7. Antagonism by anticholinesterases 6/e p339 - Solution 3) Progression to dual blockade Drug not acting on neuromuscular junction is:
  8. Baclofen
  9. Carisoprodol
  10. Haloperidol
  11. All of the above /e p457 - Solution 4) All of the above Mechanism of action of curare is:
  12. Reducing end plate potential
  13. Reducing presynaptic potential
  14. Inhibits k+ channels
  15. Inhibits Na+channels 6/e p344 - Solution 1) Reducing end plate potential The term "balanced anaesthesia" has been given by:
  16. Simpson
  17. Fischer
  18. Lundy
  19. Mortan 7/e p348 - Solution 3) Lundy Regarding propofol, which one of the following is false:
  20. It is used as an intravenous induction agent
  21. It causes severe vomiting
  22. It is painful on injecting intravenously
  1. It has no muscle relaxant property Goodman Gilman 12/e p528 - Solution 2) It causes severe vomiting Eutectic mixture of local anaesthetic (EMLA) cream is:
  2. Bupivacaine 2.0% + Prilocaine 2.5%
  3. Lidocaine 2.5% + Prilocaine 2.5%
  4. Lidocaine 2.5% + Prilocaine 5%
  5. Bupivacaine 0.5% + Lidocaine 2.5% 7/e p382 - Solution 2) Lidocaine 2.5% + Prilocaine 2.5% Ketamine produces:
  6. Emergence delirium
  7. Pain on injection
  8. Bronchoconstriciton
  9. Depression of cardiovascular system 7/e p366 - Solution 1) Emergence delirium Cocaine overdose presents with all of the following except:
  10. Diaphoresis
  11. Hypertension
  12. Constricted pupils
  13. Agitation 7/e p384 - Solution 3) Constricted pupils Baclofen is used in the treatment of:
  14. Schizophrenia
  15. Depression
  16. Anxiety
  17. Spasticity 7/e p365 - Solution 4) Spasticity Local anaesthetic used as an antiarrhythmic agent is:
  18. Bupivacaine
  19. Lignocaine
  20. Cocaine
  21. Chlorprocaine

7/e p353-354 - Solution 2) Lignocaine Pin index of oxygen is which one of the following:

  1. 2, 5
  2. 3, 5
  3. 1, 5
  4. 3, 6 7/e p366 - Solution 1) 2, 5 Which of these can be safely stopped before an abdominal surgery?
  5. ACE inhibitors
  6. Beta blocker
  7. Statins
  8. Steroids CMDT 2014/45-47 - Solution 1) ACE inhibitors Which anaesthetic modality is to be avoided in sickle cell disease?
  9. General Anaesthesia
  10. Brachial Plexus Block
  11. Intravenous Regional Anaesthesia
  12. Spinal Anaesthesia Short textbook of Anesthesia by Ajay Yadav 2/e p148 - Solution 3) Intravenous Regional Anaesthesia Which of the following induction agent produce cardiac stability?
  13. Ketamine
  14. Etomidate
  15. Propofol
  16. Midazolam /e p437 - Solution 2) Etomidate Anaesthetic agent which is explosive in the presence of cautery:
  17. Nitrous oxide
  18. Ether
  19. Trilene
  1. Halothane Goodman & Gilman 11/e p341; KDT 6/e p371 - Solution 2) Ether Ketamine is the preferred anaesthetic for the following EXCEPT:
  2. Hypertensives
  3. Trauma cases that have bled significantly
  4. Burn dressing
  5. Short operations on asthmatics 6/e p376 - Solution 1) Hypertensives An anaesthetic agent with boiling temperature more than 75°C is:
  6. Ether
  7. Halothane
  8. Cyclopropane
  9. Methoxyflurane Anesthesiology by Longnecker 2008/777 - Solution 4) Methoxyflurane All of the following are halogenated anaesthetic agents except:
  10. Halothane
  11. Propofol
  12. Enflurane
  13. Isoflurane 6/e p375 - Solution 2) Propofol Profound analgesia is produced by which parenteral anesthetic?
  14. Thiopental
  15. Propofol
  16. Ketamine
  17. ' Etomidate 6/e p377 - Solution 3) Ketamine All of the following statements about lignocaine are true EXCEPT:
  18. It blocks active sodium channels with more affinity than resting sodium channels
  19. It can cause cardiotoxicity
  20. It is given orally for treatment of cardiac arrhythmias
  1. Adrenaline increases the duration of action of lignocaine when used for infiltration anaesthesia. Katzung 12/e p453, 457, 458 - Solution 3) It is given orally for treatment of cardiac arrhythmias Anaesthetic agent with vasoconstrictor is contraindicated in?
  2. Digital block
  3. Spinal block
  4. Epidural block
  5. Regional anaesthesia /e p446 - Solution 1) Digital block Which of the following statements is not true of local anaesthetics?
  6. The local anaesthetic is required in the unionized form for penetrating the neuronal membrane
  7. The local anaesthetic approaches its receptor only from the intraneuronal face of the Na+ channel
  8. The local anaesthetic binds to its receptor mainly when the Na channel is in the resting state
  9. The local anaesthetic combines. with its receptor in the ionized cationic form 6/e p352, 353 - Solution 3) The local anaesthetic binds to its receptor mainly when the Na channel is in the resting state The local anaesthetic with the longest duration of action is :
  10. Procaine
  11. Chlorprocaine
  12. Lignocaine
  13. Dibucaine 6/e p358 - Solution 4) Dibucaine Eutectic lignocaine-prilocaine has the following unique property:
  14. It causes motor blockade without sensory block
  15. By surface application, it can anaesthetize unbroken skin
  16. It is not absorbed after surface application
  17. It has strong vasoconstrictor action 6/e p357 - Solution 2) By surface application, it can anaesthetize unbroken skin An agent added to local anesthetics to speed the onset of action is:
  18. Methylparaben
  1. Bicarbonate
  2. Fentanyl
  3. Adrenaline 6/e p412 - Solution 2) Bicarbonate Bicarbonate-- To speed the onset of action Adrenaline-- To prolong the duration of action All of the following are properties of local anesthetics EXCEPT:
  4. Blockade of voltage dependent Na' channels
  5. Preferential binding to resting channels
  6. Slowing of axonal impulse conduction
  7. Increase in the membrane refractory period 6/e p415 - Solution 2) Preferential binding to resting channels The fall in blood pressure caused by d-tubocurarine is due to:
  8. Reduced venous return
  9. Ganglionic blockade
  10. Histamine release
  11. All of the above Lee 12/e p167, KDT 6/e p372; Ajay yadan 2/e p61,66 - Solution 4) All of the above One of the following statements about succinylcholine is true:
  12. It may induce life threatening hyperkalemia
  13. It has a long duration of action
  14. It is the drug of choice in non traumatic rhabdomyolysis
  15. It is useful in patients with spinal cord injuries with paraplegia 6/e p349 - Solution 1) It may induce life threatening hyperkalemia In pseudocholinesterase deficiency, drug to be used cautiously is
  16. Barbiturate
  17. Succinylcholine
  18. Halothane
  19. Gallamine 6/e p348 - Solution Regarding muscle relaxants which one of the following is true:
  1. Atracurium is contraindicated in renal failure
  2. Pancuronium causes bradycardia
  3. Cis - atracurium is a depolarizing muscle relaxant
  4. Vecuronium induced muscle relaxation can be reversed by neostigmine Nurse Anaesthesia by John J. Nagelhout p77 - Solution Which of the following intravenous induction agent suppress steroidogenesis?
  5. Thiopentone
  6. Propofol
  7. Ketamine
  8. Etomidate Goodman and Gilman, 12/e p538 - Solution 4) Etomidate Which general anaesthetic selectively inhibits excitatory NMDA receptors:
  9. Thiopentone
  10. Halothane
  11. Desflurane
  12. Ketamine 6/e p376 - Solution 4) Ketamine Which of the following general anaesthetics has poor muscle relaxant action?
  13. Ether
  14. Nitrous oxide
  15. Halothane
  16. Isoflurane 6/e p371 - Solution 2) Nitrous oxide As a general anaesthetic, halothane has the following advantages EXCEPT:
  17. Very good analgesic action
  18. Non-inflammable and non-explosive
  19. Reasonably rapid induction of anaesthesia
  20. Pleasant and non-irritating 6/e p372 - Solution 1) Very good analgesic action Shivering" is observed in the early part of postoperative period due to:
  21. Chloroform
  1. Halothane
  2. Trichloroethylene
  3. Ether Ajay yadav 2/e p61 - Solution 2) Halothane Which of the following agents is most commonly used to induce anaesthesia:-
  4. Thiopentone sodium
  5. Methohexitone sodium
  6. Propofol
  7. Etomidate /e p434 - Solution 1) Thiopentone sodium Which of the following increase the speed of induction with an inhalational agent?
  8. Opiate pre-medication
  9. Increased alveolar ventilation
  10. Increased cardiac output
  11. Reduced FIO /e p427 - Solution 2) Increased alveolar ventilation Maximum dose of lignocaine given with adrenaline for infiltration anaesthesia is:
  12. 3 mg/kg
  13. 5 mg/kg
  14. 7 mg/kg
  15. 10 mg/kg Goodman and Gilman 12/e p576 - Solution 3) 7 mg/kg From which of the following routes, absorption of local anaesthetic is maximum?
  16. Intercostal
  17. Epidural
  18. Brachial
  19. Caudal Miller's Anaesthesiology/591 - Solution 1) Intercostal Blockade of nerve conduction by a local anesthetic is characterized by:
  20. Greater potential to block a resting nerve as compared to a stimulated nerve
  21. Need to cross the cell membrane to produce the block
  1. Large myelinated fibers are blocked before the unmyelinated fibers
  2. Cause consistent change of resting membrane potential Katzung 10/e p417; KDT 6/e p353 - Solution 2) Need to cross the cell membrane to produce the block The following local anaesthetic raises BP instead of tending to cause a fall:
  3. Cocaine
  4. Dibucaine
  5. Lignocaine
  6. Procaine 6/e p356, 357 - Solution 1) Cocaine The duration of spinal anaesthesia depends on all of the following EXCEPT:
  7. Local anaesthetic that is used
  8. Concentration of the local anesthetic used
  9. Posture of the patient
  10. Whether adrenaline has been added to the local anaesthetic 6/e p360 - Solution 4) Whether adrenaline has been added to the local anaesthetic ???????? A patient receives a toxic dose of lignocaine i.v., the patient is likely to exhibit:
  11. Excessive salivation
  12. Mydriasis and diarrhea
  13. Respiratory paralysis
  14. Seizures and coma 6/e p356 - Solution 4) Seizures and coma Epinephrine added to a solution of lignocaine for a peripheral nerve block will:
  15. Increase risk of convulsions
  16. Increase the duration of action of the local anesthetic
  17. Both (a) and (b)
  18. None of these 6/e p354 - Solution 2) Increase the duration of action of the local anesthetic Which of the following local anaesthetics belongs to the ester group?
  19. Procaine
  20. Bupivacaine
  1. Lignocaine
  2. Mepivacaine /e p441 - Solution 1) Procaine Which one of the following skeletal muscle relaxants causes pain on injection?
  3. Succinyl choline
  4. Vecuronium
  5. Rocuroniurn
  6. Pancuronium Pharmacology for Nurse Anaesthesiology/110 - Solution 3) Rocuroniurn True statement regarding depolarizing neuromuscular blocking drugs is:
  7. The depolarized muscles fibres are unresponsive to other stimuli
  8. Causes muscular fasciculations
  9. Not reversed by neostigmine
  10. All of the above /e p463 - Solution 4) All of the above The drug inactivated in plasma by spontaneous non- enzymatic degradation is:
  11. Atracurium
  12. Vecuronium
  13. Pipecuronium
  14. Pancuronium /e p462-464 - Solution 1) Atracurium Which one of the following drugs is not a long acting neuromuscular blocking agent?
  15. Doxacurium
  16. Mivacurium
  17. Pancuronium
  18. Pipecuronium 6/e p345 - Solution 2) Mivacurium All of the following are the true for post lumbar puncture headache except:
  19. Presents 12 hours after procedure
  20. Pain is relieved in standing position
  21. Pain is worsened by head shaking
  22. Pain is occipito-frontal in location

7/e p358 - Solution 2) Pain is relieved in standing position All of the following are intravenous anesthetic induction agents except:

  1. Thiopentone sodium
  2. Ketamine
  3. Etomidate
  4. Bupivacaine 7/e p513 - Solution 4) Bupivacaine The minimal alveolar concentration of an inhalational anaesthetic is a measure of its:
  5. Potency
  6. Therapeutic index
  7. Diffusibility
  8. Oilwater partition coefficient 6/e p365 - Solution 1) Potency Malignant hyperthermia is a rare complication of the use of the following anesthetic:
  9. Ketamine
  10. Thiopentone sodium
  11. Halothane
  12. Ether 6/e p372 - Solution 3) Halothane Following accidental intra-arterial injection of thiopentone, which should not be done?
  13. Remove the needle
  14. Intra -arterial heparin
  15. Intra-arterial papaverine
  16. Do a stellate ganglion block Ajay yadav 2/e p73 - Solution 1) Remove the needle Ram has a 4 ml lignocaine vial of 2% solution. How much lignocaine is present in 1 ml?
  17. 2 mg
  18. 8 mg
  19. 20 mg
  20. 200 mg

6/e p356, 357 - Solution 3) 20 mg %= gm/dl solution. The mechanism of action of local anesthetics is that they act on Na+ channels in their:

  1. Activated state
  2. Inactivated state
  3. Resting state
  4. Any state /e p443 - Solution 1) Activated state Muscular rigidity caused by opioids is due to the agonistic effect on which receptor?
  5. Mu
  6. Kappa
  7. Delta
  8. Sigma Miller 7/e p781 - Solution 1) , Mu Neostigmine antagonizes non-depolarizing blockade by all of the following mechanisms EXCEPT:
  9. Decreasing the breakdown of acetylcholine at the motor end plate
  10. Preventing the K+ efflux from the cell
  11. Increasing the release of acetylcholine at the motor end plate
  12. Depolarization at the motor end plate Katzung 10/e p436; KDT 6/e p99-101 - Solution 2) Preventing the K+ efflux from the cell The following antibiotic accentuates the neuromuscular blockade produced by pancuronium:
  13. Streptomycin
  14. Erythromycin
  15. Penicillin G
  16. Chloramphenicol 6/e p345 - Solution 1) Streptomycin A patient with ruptured spleen is taken for laparotomy. His blood pressure is 80/50 and heart rate is 125/min. Induction agent of choice for this patient is:
  17. Sodium Thiopentone
  18. Fentanyl
  1. Ketamine
  2. Halothane Goodman and Gilman 12/e p538-539 - Solution A 32 year old male is a known hypertensive and is being planned for cholecystectomy. Which of the following anaesthetic agents is contraindicated in this person?
  3. Propofol
  4. Ketamine
  5. Midazolam
  6. Etomidate /e p437 - Solution 2) Ketamine A patient with mitral stenosis had to undergo surgery. Pre-anaesthetic checkup revealed the increased liver enzymes. Which of the following inhalational agent should be preferred in this patient?
  7. Xenon
  8. Enflurane
  9. Halothane
  10. Sevoflurane Goodman and Gilman 12/e p547-548, Morgan's Clinical Anaesthesiology, 11/e p166-167, Wiley 7/e p527-532 - Solution 1) Xenon Nitrous oxide is contraindicated in patients with pneumothorax, pneumopericardium or intestinal obstruction, because it:
  11. Depresses an already compromised myocardium
  12. Permits the use of limited FI02 only
  13. Is less soluble than nitrogen
  14. Causes the expansion of air filled body cavities Goodman and Gilman 12/e p547 - Solution 4) Causes the expansion of air filled body cavities A 5 years old child is suffering from cyanotic heart disease. He is planned for corrective surgery. The induction agent of choice would be:
  15. Thiopentone
  16. Ketamine
  17. Halothane
  18. Midazolam Ajay Yadav 2/e p215 - Solution 2) Ketamine