Download ARDS Question and answers already passed and more Exams Nursing in PDF only on Docsity! ARDS What is the histopathologic counter part of ARDS? What does it demonstrate? - correct answer Diffuse alveolar damage Demonstrates diffuse damage to the alveolar-capillary interface, resulting in exudative edema and hyaline membrane formation What is the major cause of death in patients with ARDS? - correct answer Multi-organ failure What is a common complication of ARDS a couple weeks into the illness? Why? - correct answer PTX -- ARDS involves destruction of lung tissue -- 2nd week is when it becomes severe enough to promote PTX When treating ARDS with mechanical ventilation, should low or high Tidal Volume be used? Why? - correct answer Lower tidal volume -- limits volume trauma to lungs and therefore reduces mortality What technique with mechanical ventilation of ARDS patients can improve mortality? - correct answer Prone Ventilation True or False: Nitric Oxide improves mortality in ARDS patients. - correct answer False -- It improves oxygenation but NOT mortality What is ARDS? - correct answer Acute Respiratory Distress Syndrome -- Severe, acute lung injury involving diffuse alveolar damage, increased microvascular permeability, and NON-CARDIOGENIC pulmonary edema What are the 4 defining features of ARDS? What are the Berlin Classifications for ARDS? - correct answer ARDS 1. Acute onset of respiratory failure 2. Ratio of PaO2/FiO2 < 300 3. Double (Bilat) infiltrates on CXR 4. Scant (no) evidence of volume overload (non-cardiogenic pulmonary edema) Berlin: Mild: PaO2/FiO2 < 300 Moderate: PaO2/FiO2 < 200 Severe: PaO2/FiO2 < 300<100 What is the pathogenesis of ARDS? - correct answer Inflammation results in release of inflammatory cytokines (IL-1, 6, 8, 10, TNF, PAF, and MIF) --> Damage to endothelium --> Exudative edema --> Dysfunctional surfactant --> ARDS What is the difference between direct and indirect causes of ARDS? - correct answer Direct causes are those that originate inside the lung Indirect causes are those that originate outside the lung What are 6 causes of direct ARDS? - correct answer Pnemonia Aspiration Drowning Trauma (penetrating lung injury) Inhalation injury Embolus (Fat) What are 6 causes of indirect ARDS? - correct answer Sepsis Bypass Drug Overdose Transfusion of blood products Severe Trauma Pancreatitis What are the 4 stages of ARDS? At what days do they occur? - correct answer Exudative -- 0-4 Proliferative -- 4-8 days Fibrotic -- > 8 days