CNPR Exam Questions and Answers, Exams of Microsoft Word Skills

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1. How are drugs sorted into therapeutic groups and classes? - correct answer first by the conditions that they are used to treat. and then by their mechanisms of action
2. Bone marrow transplants. - correct answer are a type of stem cell therapy. unless patient's own cells are reinjected.
3. What does AMA stand for? - correct answer American Medical Association
4. What section of a drug's package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits? - correct answer contraindications 5 What is tertiary care? - correct answer highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems
5. Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual? - correct answer brand quality 7 What are vasodilators used to do? - correct answer decrease vascular resistance and increase blood flow

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8. What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant? - correct answer Steady State
9. Which statement is TRUE about ocular administration? - correct answer Ocular administration is used primarily to treat the eye.
10. Which entities invest's the most money in pharmaceutical R&D? - correct answer U.S. pharmaceutical companies
11. How are most drugs excreted? - correct answer via the kidneys
12. Over the last few decades, what has happened to legal limitations on sales' reps discussions about off label uses? - correct answer Limitations have decreased.
13. What does it mean if two drugs are at parity? - correct answer Both drugs are essentially in a neutral position. 15 Who is most likely to benefit from electronic sampling programs? - correct answer Everyone would benefit equally from electronic sampling programs

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16. When referring to medication dosage, which abbreviation means "one-half' - correct answer SS 17 What is an internist? - correct answer a physician who practices internal medicine
17. Which of the following is a type of white blood cell? - correct answer Lymphocytes
18. Why are novice sales representatives often placed in charge of negotiating MCO formularies? - correct answer They are not. This job is usually reserved for more experienced reps.
19. What distinguishes pharmacodynamics from pharmacokinetics? - correct answer Pharmacodynamics studies the how the body affects drugs. 21 What proportion of the drugs tested on human subjects are eventually approved by the FDA? - correct answer about 70%
20. According to a study discussed in your manual, how do most physicians prefer to receive their drug samples? - correct answer directly from sales representatives

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23. Which of the following is an example of a central value? - correct answer I buy Advil to show that I'm a modern consumer.
24. Which of the following specialties likely has the MOST emergency calls? - correct answer cardiologist
25. What affects the rate of active transport? - correct answer neither the availability of carriers nor the availability of energy
26. Over the last few decades, what has happened to the FDA approval time for new drugs? - correct answer It has been shortened to reduce the cost of new drug development.
27. Which of the following would NOT help improve compliance? - correct answer pharmacists understanding how generics differ from brand name drugs
28. Which entity chooses a drug's trade name? - correct answer the FDA
29. What type of stem cells are obtained from embryos and can develop into any cell type? - correct answer totipotent

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30. As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it? - correct answer It remains unaffected because the prescription is needed
31. Most involuntary movements come from which type of muscle tissue? - correct answer cardiac and smooth
32. Which of the following is NOT one of the body's major organ systems? - correct answer the cellular system
33. How do most drugs exert their primary physiological effects? - correct answer by binding to cell receptors that are sensitive to their presence
34. What is the most reliable source of information for determining therapeutically equivalent drug products? - correct answer Orange Book
35. What does subcutaneous mean? - correct answer beneath the outer skin

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36. What should a sales representative do if all of the prime spaces in a drug cabinet are coccupied? - correct answer ask staff for permission to move some of the other products in the cabinet
37. It is inappropriate for physicians' prescribing behaviors to be educated by their personal tastes and idiosyncrasies - correct answer TRUE 38.The FDA defines API as the active__ ingredient in a drug, which produces the desired change in the body. - correct answer pharmaceutical
38. What are the 2 legal classifications of wholesalers? - correct answer primary and secondary wholesale distributors 40.What term describes the usage of a medication for purposes other than the FDA-approved indications on the labeling? - correct answer off-label usage
39. What is the acronym for pharmacokinetics? - correct answer PK
40. The dosage range of a drug that is both safe and beneficial is known as the therapeutic window. - correct answer True

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43. What is typically NOT a characteristic of a pharmaceutical sales rep?

• correct answer Pharmaceutical sales reps are not concerned about competitors.

44. What entity grants drug patents? - correct answer The US Patent and Trademark Office
45. Which of the following refers to all active and inert pharmaceutical ingredients in a drug,including fillers and colors? - correct answer formulation
46. What is the difference between potency and efficacy? - correct answer potency refers to the drug's strength, while efficacy refers to its effectiveness
47. What is the minimum level of education required for a nurse practitioner? - correct answer a graduate degree
48. How many names must a drug have? - correct answer at least three
49. How has a longer development time increased the cost of bringing a new drug to market? - correct answer Increasing the cost of capital

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50. Senior citizens consume over times as many pharmaceuticals as people under 65. - correct answer three
51. What agency regulates the distribution and use of narcotics? - correct answer DEA
52. What is passive diffusion? - correct answer when a substance freely moves through a membrane from a high concentration gradient to a low one
53. What are the MAIN categories of drugs under FDA jurisdiction? - correct answer prescription and non prescription
54. What are all metabolites? - correct answer products of metabolism
55. When a drug is administered orally, where does first-pass metabolism occur? - correct answer liver
56. What is the medical term for swelling? - correct answer edema
57. Which of the following is NOT part of the Seven Step Cascade of Emotion? - correct answer be a consultant, not a rep

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59. Which part of a clinical research paper is frequently referred to as the road map? - correct answer abstract
60. Which of the following is a main active ingredient in lung surfactants? - correct answer theophylline
61. What does parenteral mean? - correct answer injection
62. Which term denotes a type of substance that enhances the action of a drug or antigen? - correct answer adjunvant
63. If a sales representative's product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true?

• correct answer It probably has exclusive preferred status if it is not at parity with any other drugs

64. Which of the following is NOT one of the four basic transport mechanisms? - correct answer homeostasis
65. Which statement accurately describes a relationship between drug agonists and antagonists? - correct answer Agonists and antagonists can be used together.

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66. What is the study of the effects and movement of drugs in the human body? - correct answer clinical pharmacology
67. According to your manual, what is a common complaint that physicians have about traditional sampling methods? - correct answer that drug sample supply is too unpredictable
68. Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power? - correct answer GPO
69. What is another name for a drug derived from a biologic compound? - correct answer large molecule
70. What is the most common policy regarding pharmaceutical reps dispensing drug samples in hospitals? - correct answer drug sampling is often forbidden 71 Which of the following would help you build trust with a physician? - correct answer asking if he or she is having any problems with the managed care coverage of your products

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72. What term denotes the difference between the usual effective dose and the dose that induces severe or life-threatening side effects? - correct answer margin of safety
73. What are excipients? - correct answer the inert ingredients in a drug formulation
74. What is another term for the AWP? - correct answer list price
75. Which of these is the most likely use for a uterotonic agent? - correct answer to induce labor
76. As of November 2013, which of these countries has legalized DTC advertising of prescription drugs? - correct answer none of these
77. Why are oral drugs often taken on an empty stomach? - correct answer to pass through the stomach more quickly
78. What is one factor that differentiates community health centers from hospitals? - correct answer community health center formularies are more restrictive

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79. How does drug sampling provide a social benefit? - correct answer doctors often use drug samples to treat patients who otherwise could not afford it
80. Which medical term denotes the use of a stethoscope to listen to the heart? - correct answer ausculation
81. What do enteric coatings do? - correct answer prevents dissolution in the stomach
82. What is the duration of exclusivity for orphan drugs? - correct answer 7 years
83. What do National Account Managers do? - correct answer negotiate contracts with MCO and PBM
84. What does it usually mean if a drug recall is voluntary? - correct answer The manufacturer has recalled the product on its own. but negotiated with the FDA beforehand.
85. Which phase of clinical trials is also known as the pivotal phase? - correct answer Phase III

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86. During which phase of clinical trials is the new drug's safety and effectiveness first tested in the target group? - correct answer Phase II
87. How do antacids work? - correct answer by raising gastric PH
88. What is one of the biggest time wasters for a pharmaceutical sales rep? - correct answer Travel Time
89. What happens when equilibrium is reached? - correct answer equal numbers of molecules cross the membrane in both directions
90. What are the most common vectors used in gene therapy? - correct answer viruses
91. What is the percentage fee that the dispenser pays the wholesaler for distribution? - correct answer upcharge
92. What is the difference between a chronic (or continuing) reaction, and a delayed reaction? - correct answer chronic reactions persist for a long time, delayed reactions take some time to develop 93 What is clinical effect? - correct answer the response produced by a medication

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94. Which of the following is an example of noncompliance? - correct answer a patient forgetting to take a drug at a specified time of day
95. What is the average circulation time of blood? - correct answer about a minute
96. What is one way in which pharmaceutical selling is different from selling in most other industries? - correct answer representative do NOT sell to the end user of the product
97. From what types of entities do primary wholesale distributors buy most of their drugs? - correct answer manufacturers 98.What is the Office of the Inspector General (01G)? - correct answer an arm of the Dept of Health and Human Services
98. What are doctors required to consider when deciding whether or not to prescribe a particular drug? - correct answer the severity of the disorder being treated and the effect it has on the patients quality of life
99. Which entity assigns a new drug its generic names? - correct answer the United States Adopted Name Council

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101. Drugs can be used days beyond their expiration date. - correct answer drugs never can be used beyond expiration date
102. What is necessary for a drug to be excreted extensively via the kidneys? - correct answer The drug must be water-soluble, and not bind too tightly to protein in the bloodstream
103. Which organization or individual initiates the clinical trial and finances the study? - correct answer sponsor
104. The name describes the atomic or molecular structure of a drug. - correct answer chemical
105. Under PhRMA Code, is it acceptable or unacceptable for a pharmaceutical sales rep to take a physician and the physician's spouse to a fundraising dinner? - correct answer never (unacceptable)
106. The Hatch-Waxman Act is considered the most significant drug- related affecting the pharmaceutical industry since 1962. - correct answer legislation

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107. What term denotes the the extent, quality, or degree to which a substance is poisonous or harmful to the body? - correct answer toxicity
108. What issue has MOST encouraged consumers' desire to see more OTC medications? - correct answer lack of insurance coverage
109. What is the degree to which a medication produces a therapeutic effect? - correct answer efficacy
110. What is the most important benefit of electronic prescribing? - correct answer safety
111. When does the FDA regulate generic drugs? - correct answer always
112. Which phase of trials largely determines the clinical dose? - correct answer Phase II trials
113. What is an advantage of inactivated vaccines over attenuated vaccines? - correct answer inactive vaccines have a more stable shelf life

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114. Which medical term denotes a low supply of oxygen due to low blood flow? - correct answer ischemia
115. What are the two main types of prescription drug marketing? - correct answer professional physician promotions and direct-to- consumer advertising
116. What is the site of delivery for subcutaneous injections? - correct answer fatty tissue beneath the surface of the skin
117. What must be contained in the Description section of a pharmaceutical package insert? - correct answer the proprietary name and the established name
118. What is the study of a medication's effects as it travels through the body? - correct answer pharmacokinetics
119. Customers purchase products from people they like, trust, and respect. This is called the - correct answer likeability factor
120. What is penicillin's primary mechanism of action? - correct answer it disturbs bacterial cell wall synthesis

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121. According to your manual, how has the U.S. healthcare marketplace changed in the last few decades? - correct answer managed care has been increasingly replaced by more patient centered approaches
122. How does pharmaceutical marketing help narrow the treatment gap? - correct answer it encourages patients to take more active roles in their healthcare
123. What do immunosuppressive agents do? - correct answer reduce risk of rejection of foreign bodies
124. What types of drugs are EGFR inhibitors? - correct answer antineoplastics
125. Which of the following means outside of the living body? - correct answer ex vivo
126. The FDA requirements for nutraceuticals and medicinal herbs are just as stringent as for pharmaceuticals. - correct answer False
127. What is the estimated net gain of private-sector healthcare's contributions to increased U.S. life expectancy? - correct answer 2- trillion

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128. Which statement is TRUE regarding post-approval drug monitoring? - correct answer the FDA can choose to withdraw their approval if new evidence arises
129. Which term denotes when tolerance to one medication causes increased tolerance to another medication? - correct answer cross tolerance
130. Patents expire __ years from the date of filing. - correct answer twenty
131. After a trade-name drug's patent expires, how may generic versions of it be sold? - correct answer only under the branded generic name
132. What is required for a new pharmaceutical to be considered a viable therapy? - correct answer it is more effective, causes fewer serious adverse effects than other drugs on the market
133. Under the AMA guidelines, who is ultimately responsible for minimizing conflicts of interest? - correct answer doctors

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134. The act of dispensing a pharmaceutical alternative for the product prescribed is - correct answer pharmaceutical substitution
135. What does it mean if a drug is said to have a wide margin of safety? - correct answer there is a lower chance of severe or life threatening side effects
136. Which of the following is the correct medical acronym for effective dose? - correct answer ED
137. Why is one group of subjects given an active drug, while another group only receives a placebo? - correct answer to assess the drugs effectiveness
138. A generic version is likely to have some inactive ingredients that are different from those of the original drug. - correct answer True
139. Which of the following is an example of a functional value? - correct answer I drink coco cola because I like the taste
140. Where are most drugs metabolized? - correct answer liver

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141. What is essential to the ethical requirement that subjects be selected fairly? - correct answer subjects should be selected based on scientific objectives
142. Which of the following is the most appropriate salutation for a cover letter if you cannot find a contact name? - correct answer Dear Sir or Madam
143. What is part of becoming an indispensable pharmaceutical sales rep? - correct answer asking for feedback
144. Which of the following is NOT typically included in the indications and usage section of the package insert information? - correct answer the drugs active metabolites
145. Which term denotes the practice of classifying physicians and other potential prescribers by anticipated prescription volume? - correct answer deciling
146. What makes a drug eligible for fast track approval from the FDA? - correct answer it treats patients with a serious life-threatening condition

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147. In the gastrointestinal tract, help break up tablets to ensure full release of the active pharmaceutical ingredient. - correct answer disintegrants
148. According to your manual, what does the PDRP do? - correct answer it limits sales reps abilities to see individual physicians prescribing data
149. What are the components of the central nervous system? - correct answer the brain and spinal cord
150. Which term denotes the origin or cause of a medical condition? - correct answer etiology
151. Patients diagnosed with Type 1 diabetes - correct answer have an autoimmune disease
152. Which DTC pharmaceutical marketing tactic is permitted in European countries? - correct answer disease state ads
153. What is one way in which psychologists DIFFER from psychiatrists?

• correct answer psycologist deal with emotional than physical issues

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154. What are PBMs? - correct answer organizations that negotiate between pharmaceutical companies and large drug purchasers
155. How does the Hatch-Waxman Act protect research-based drug manufacturers? - correct answer by providing a 30 month cooling off period
156. What is the process of adjusting drug doses to achieve the maximum positive therapeutic effects while minimizing adverse or side effects? - correct answer titration
157. Which of the following is studied more in pharmacodynamics than in pharmacokinetics? - correct answer the transportation of the drug to the specific site for drug receptor interactions
158. How does the healthy human immune system use MHC markers? - correct answer substances without MHC markers are discerned as foreign and targeted for destruction
159. What is a behind-the-counter drug? - correct answer an OTC drug that must be closely monitored by the pharmacist
160. When do MSLs meet with clinicians? - correct answer at nearly any stage of the products life cycle