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Final Exam Study Guide/Final Exam Study Guide latet, Exams of Health sciences

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2021/2022

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Head to Toe Head & Neck ● Lymph nodes (10) Eyes ● Inspect for color, shape, symmetry, position, & alignment of eyes Corneal light reflex: light appears equally in the same spot on both pupils; strabismus (cross eye) Conjunctiva & sclera Bulbar conjunctiva: delicate mucous membrane that covers the exposed surface of the sclera (white) Palpebral conjunctiva: membrane that lines the anterior portion of sclera (uniformly pink) Lids: Lacrimal apparatus Nasolacrimal sac: upper dilated end of the nasolacrimal duct; is lodged in a deep groove formed by the lacrimal bone & frontal process of the maxilla ● Confrontation ○ Peripheral vision Pt can see fingers enter visual field (180 degrees) CN 2 Optic: S (visual acuity) ○ Snellen (far vision): myopia/nearsightedness ○ Rosenbaum (arms length): hyperopia/farsightedness ○ Ishihara (color vision) od/os/ou ● PERRLA ○ Pupils ○ Equal ○ Round ○ Reactive to Light ■ CN 3 Oculomotor: M

Pupillary constriction (bringing light in from the side) ○ Accommodation ■ Constrict & converge (focus on something, then refocus on pen) ● Cardinal Positions of gaze (nystagmus or involuntary rapid eye movements, drifting) CN 3 Oculomotor: M CN 4 Trochlear: M CN 6 Abducens: M Cataracts: cloudy or opaque areas in the ocular lens, temporary Risk factors: Increasing age, Diabetes, high BP Glaucoma: a group of eye conditions that can cause blindness; often caused by an abnormally high pressure in your eye; permanent Risk factors: having high internal eye pressure (intraocular pressure) ● Terms (exam 4) Wk 9 terms: https://quizlet.com/585839860/week-9-terms- flash-cards/ Ears ● Inspect & palpate auricles for redness, swelling, tenderness Inspect external canal for redness, swelling, drainage, cerumen, foreign bodies Otitis externa: inflammation of external ear; allergic reaction to beauty/personal care products Otitis media: inflammation of middle ear; common in pt’s with environmental/seasonal allergies ● Weber (lateralization) ○ Vibration and sound equal bilaterally ● Rinne ( AC>BC 2:1) ○ Pt unable to hear or feel the sensation in one ear during Weber ○ Conduction : air conduction to bone conduction, hear it twice as long as you should be able to feel it ❖ Whisper ➢ Able to identify words Nose ● Inspect nares for symmetry, lesions, tenderness Inspect internal nares for inflammation, drainage

○ Make sure septum is midline, not deviated ○ Septal deviation: a condition in which the nasal septum (the bone and cartilage that divide the nasal cavity of the nose in half) is significantly off center, or crooked, making breathing difficult ○ Palpate pt’s nose assessing for pain, tenderness, swelling & deformity? CN 1 Olfactory: S ○ Can smell ⅔ odors ○ Patency: air is moving freely within nasal cavity Palpate sinuses ○ Frontal: superior orbital rim above eyebrow ○ Maxillary: superior aspect of the cheek bones (around eyes) ● Terms ○ Epistaxis: Nosebleed ○ Nasal flaring: Occurs when the nostrils widen while breathing; often a sign of trouble breathing ○ Nasal discharge: Excess drainage, ranging from a clear fluid to thick mucus, from the nose and nasal passages; rhinorrhea Mouth & Throat ● Inspect Lips: color, moisture, cracking, lesions, Oral mucosa: color, moisture, lesions (moist & pink) Gums: color, swelling, retraction of gingiva, lesions (pink, smooth moist) Teeth: decay, alignment Glossopharyngeal 9 & Vagus 10: B Soft palate/uvula movement Smooth, moist, pink, rises w vocalization Uvula is midline Speech quality Swallow ■ Dysphagia: difficulty swallowing Gag reflex Only 9: verbalize taste Hypoglossal 12: M Color, saliva, symmetry, open areas Ease & equality of tongue movement

Strength of tongue Tonsils: color, exudate, lesions ● Thyroid assessment ● Throat pain ● Swollen lymph nodes ● Thrush: An infection in which the fungus Candida albicans accumulates in the mouth Cardiovascular ● Inspect/palpate color, temperature, texture of skin, hair distribution in extremities Observe the neck and precordium for visible pulsations Precordium: portion of the body over the heart and lower thorax, APEToMan Capillary refill < 3 seconds ● S1: best heard at apex (loudest in mitral); closure of mitral & tricuspid valves; “LUB”; low pitched & dull; beginning of ventricular systole ● S2: best heard in aortic area at base of heart; closure of aortic & pulmonic valves; “DUB”; end of ventricular systole; shorter, higher- pitched, louder sound than S ● S3: ventricular gallop; may be cardinal sign of heart failure in adults; best heard at apex with pt lying on left side; low-pitched; the y sound in “Ken-tuck-y”; follows S2; may also be associated with such conditions as pulmonary edema, atrial-septal defect, acute MI and last trimester of pregnancy ● S4: atrial gallop; heard over tricuspid or mitral areas with pt on left side; heard in elderly, or those with HTN, aortic stenosis, or a history of MI; commonly describe as sounding like; “Ten-nes-see” ○ Murmurs: regurgitation of blood between atrium & ventricles (valve isn't closing all the way) ○ Thrills: palpable vibration: usually valvular dysfunction ○ Heaves: lifting of the chest wall felt during palpation ○ Bruits: abnormal “swooshing or blowing” heard over blood vessel; stenosis or occlusion Feel a thrill, hear a bruit ❖ APETM ➢ Aortic: 2nd^ intercostal space R sternal border Pulmonic: 2nd^ intercostal space L sternal border Erb's point: 3rd^ intercostal space L sternal border

Tricuspid: 4th^ intercostal space L sternal border Mitral: 5th^ intercostal space Midclavicular line Bell & diaphragm S1, S2 present, no murmurs, no abnormal sounds ❖ Aortic impulse ➢ 5th intercostal space, midclavicular line or MITRAL (palpate) Small pulsation is normal only in this location ❖ Pulses ➢ Radial pulse at the same time Dorsalis pedis pulse at the same time Or all of them? +2, regular, equal bilaterally ❖ Edema ➢ If pt has, grading (+1 to +4: pitting, non-pitting, brawny, dependent) 1+: 2mm, slight imprint/trace; pulse weak (0 or absent) 2+: 4mm, moderate; pulse normal 3+: 6mm, deep; pulse increased 4+: 8mm, leaves deep imprint that slowly returns to normal; pulse bounding No edema bilaterally (wk 1) Respiratory ❖ Inspection ➢ Inspect color (cyanosis) & respiratory effort (inspect for ease, distress, cough) ➢ Shape & configuration, AP diameter 1:2 ratio (½ transverse diameter); barrel chested Clubbing of nailsBulging of the last part of the finger with curved, convex nails Related to reduced oxygen in blood Palpate anterior & posterior for lumps, masses, tenderness Auscultate, anterior & posterior ➢ Adventitious sounds: not normally heard in the lungs & result from air moving through moisture, mucus, or narrowed airways Diminished: hear to hear, dim, “quiet”; pneumonia Crackles: bubbling, crackling, popping; low- to high-pitched,

discontinuous sounds; auscultated during inspiration & expiration; opening of deflated small airways & alveoli; air passing through fluid in the airways (CHF, pulm edema, bronchitis) Rhonchi: sonorous or coarse; snoring quality, low-pitched, continuous sounds; auscultated during inspiration & expiration; coughing may clear the sound somewhat; air passing through or around secretions (bronchitis, COPD, cystic fibrosis) Rub: rubbing or grating; loudest over lower lateral anterior surface; auscultated during inspiration & expiration; inflamed pleura rubbing against chest wall Noting that all lung fields are clear & the pt was breathing regularly w/ no difficulty or use of accessory muscles ❖ Percussion ➢ Anterior and posterior thoracic region (lean forward, round shoulders) Location, shape, size density of tissues Resonance: the prolongation & intensification of sound produced by transmission of its vibrations to a cavity during percussion; air filled, normal lung tissue Hyperresonance: greater than normal resonance (the prolongation & intensification of sound produced by transmission of its vibrations to a cavity), often of a lower pitch, elicited during percussion; pneumothorax Dull: the sound obtained by percussing over a solid body part that does not resonate, usually obtained over a body part or area containing less air than those parts or organs that do resonate; liver, mass, lobar pneumonia Flat: the sound obtained by percussion over solid areas such as bone; pleural effusion Noting terms & sounds flat, dull resonance upon percussion; equal Wheeze: musical or squeaking; high-pitched, musical, continuous sounds; auscultated during inspiration & expiration; air passing through narrowed airways (asthma, COPD) Stridor: harsh, loud, high-pitched; auscultated on inspiration; narrowing of upper airway (larynx or trachea); presence of foreign

body in airway Inspect shape & configuration, AP diameter Inspect for cyanosis (blue mucous membranes) Inspect clubbing of nails AP diameter ❖ Lobes ➢ L lung 2 lobes R lung 3 lobes Main bronchus branches > secondary bronchi (one to each lobe) > bronchioles Alveoli: small air sacs, site of gas exchange Surfactant: reduces surface tension between moist membranes of alveoli; phospholipid ❖ Terms (wk 4) https://quizlet.com/572069000/week-4-5-terms-flash- cards/ Abdominal ❖ Inspect hair, color, scars, bumps Inspect contour (flat) Inspect symmetry Epigastric: Region of the upper abdomen immediately below the ribs Umbilical: region that surrounds the area around the umbilicus; contains part of the stomach, the head of the pancreas, the duodenum, a section of the transverse colon & the lower aspects of the left & right kidney Suprapubic: region of the abdomen located below the umbilical region Auscultate FIRST: 4 quadrants, clockwise (umbilicus midline) Normoactive bowel sounds in all 4 quadrants Bowel sounds ● Normoactive: High pitched, gurgling noises; Considered normal ● Hypoactive: Heard infrequently ● Hyperactive: loud, high-pitched tinkling sounds occurring frequently; Indicative of diarrhea ● Absent: >2 min, absence of motility,

peritonitis, ileus Light palpation for guarding, rigidity, masses, tenderness, motility Identify muscle resistance & tenderness & location of some superficial organs Palpate liver to check for enlargement & tenderness Cannot detect spleen; can cause rupture Location of organs (Quadrants) RUQ ● Liver ● Right kidney ● Head of pancreas ● Duodenum ● Pylorus RLQ ● Cecum ● Appendix ● Right ureter LUQ ● Stomach ● Spleen ● Left kidney ● Body of pancreas LLQ ● Sigmoid colon Percussion: direct or indirect used to detect; size & location of abdominal organs and/or air or fluid in the abdomen, stomach or bowel Direct: strike your hand or finger directly on patients abdomen Indirect: Use middle finger of dominant hand to strike a finger resting on patient’s abdomen: Begin in RLQ and proceed clockwise to all four quadrants Do not percuss the abdomen of pt. w/ abdominal organ transplant Two sounds normally heard Tympany: clear hollow sound like drum beating heard over hollow organs Dullness: muffled sound heard over solid organs

(liver) ❖ Bruits/pulsations ❖ Peristalsis: Contractions of the circular and longitudinal muscles of the intestines; Occur every 3 to 12 minutes; Moves waste products along the length of the intestine; Controlled by nervous system ❖ Ascites: Accumulation of fluid in the peritoneal cavity; caused by advanced liver disease, heart failure, pancreatitis or cancer (wk 7) Neuro/Mental Status ●^ Inspect appearance, behavior, cognitive functions, thought processes, & perceptions They are dressed appropriately for the weather, they have appropriate cognitive function upon assessment Appropriate thought process, pts affect is appropriate for pts age Inspect position, alignment of eyes (corneal light reflex) ❖ Facial (7): Sensory & Motor ● Symmetry of smile, frown, show teeth, puffed cheeks, raised eyebrows (muscle strength) Sense of taste (sweet, sour, salty) Corneal reflex (motor response): q tip Inspect gait Smooth, rhythmic, effortless, coordinated arm swing ● Trigeminal (5): Sensory & Motor ● Symmetry of sharp & dull stimuli of face Corneal reflex (sensory stimuli) Clench teeth tightly (masseter & temporalis strength) ● Stereognosis ● Pts identification of different items (pen, paperclip, quarter) Palpate carotid ● Orientation ● Reflexes ● Tricep reflex ○ C7 to C ○ Elicits involuntary contraction of the triceps brachii muscle Patellar reflex ○ L2 to L

○ Knee-jerk reflex Babinski’s sign ○ The plantar reflex that is a reflex elicited when the sole of the foot is stimulated with a blunt instrument Musculoskeleta l ●^ Abduction: moving limb away from midline ● Adduction: moving a limb toward body’s midline ● Supination: the assumption of the supine position (laying horizontal) ● Extension: the state of being in a straight line ● Flexion: the state of being bent ● Dorsiflexion: he action of raising the foot upwards towards the shin ● Crepitus: grating sound/sensation produced by friction between bone and cartilage or the fractured parts of a bone ● Contour: outline ● Symmetry: evenness ● Scoliosis: curvature of a portion of the spine to the side, laterally ● Lordosis: curving inward of the lower back ● Kyphosis: forward rounding of the back; hunchback Terms (exam 4) https://quizlet.com/583151111/week-10-terms-flash-cards/ ❖ Cranial Nerves CN S, M, or B? Assessments Description

  1. Olfactory S ● Can smell ⅔ odors ● Patency Olfactory bulb located in frontal lobe of brain
  2. Optic S Visual Acuity: ● Snellen ● Rosenbaum ● Ishihara Retina (rods & cones) transmit info to optic nerve to process
  3. Oculomotor M ● 6 cardinal positions of gaze (nystagmus, ● Muscle function (around eyes)

drifting) ● Pupillary reaction to light (PERRLA) ● Pupil response ○ Controls size of pupil ○ Response to light

  1. Trochlear M ● 6 cardinal positions of gaze ● Superior oblique muscle ● Eye movement
  2. Trigeminal B ● Symmetry of sharp & dull stimuli ● Corneal (light) reflex: sensory ● Clench teeth tightly: masseter & temporalis strength ● Ophthalmic (forehead/scalp/upper eyelids) ● Maxillary (cheeks/upper lip/nasal cavity) ● Mandibular (ears/lower lip/chin)
  3. Abducens M ● 6 cardinal positions of gaze Eye muscle movement: ● Lateral rectus movement ● Pons
  4. Facial B ● Symmetry of smile, frown, show teeth, puffed cheeks, raised eyebrows ● Sense of taste (sweet, sour, salty) ● Corneal reflex: motor (Q tip) ● Muscle strength Pons of brainstem is complex ● Facial expressions/jaw muscles ● Sense of taste ● Supplying salivary/tear- producing glands ● Sensations to ear
  5. Acoustic (Vestibulocochlear) S Cochlear: ● Weber ● Rinne ● Whisper test Vestibular: ● Romberg test Cochlear: ● Hearing ● Pitch/vibrations Vestibular: ● Balance/equilibrium ● Linear & rotational movements of head
  1. Glossopharyngeal B ● Soft palate/uvula movement ● Speech quality ● Swallow (stylopharyngeus) ● Gag reflex ● Verbalize taste: sweet, bitter, salty ● Sinuses ● Sense of taste
  2. Vagus B ● Soft palate/uvula movement ● Speech quality ● Swallow ● Gag reflex Sensation from ● Ear canal to throat ● Chest & trunk Motor control of ● Muscles in throat ● Stimulation muscles in chest & trunk
  3. Accessory M ● Shoulder shrug ● Strength in turning head side to side: sternocleidomastoi d & trapezius muscle ● Controls muscles in neck (rotate, flex, extend) ● Spinal cord: control ● Cranial: medulla oblongata
  4. Hypoglossal M ● Ease & equality of tongue movement ● Strength of tongue ❖ Skin ➢ Melanoma A type of skin cancer that occurs when pigment producing cells called melanocytes mutate and begin to divide uncontrollably ABCDE ● Asymmetry ◆ One side does not match other ● Border ◆ Irregular, ragged

● Color ◆ Not evenly colored ● Diameter ◆ Larger than 6mm across ● Evolving ◆ Changing in size, shape or color ➢ Pressure injuries ■ Ⅰ ● Nonblanchable ● Intact skin ● Erythema (red in color) ● Epidermis Ⅱ ● Partial thickness ● Abrasions ● No adipose tissue ● Dermis ● Skin tear; blister ● No slough Ⅲ ● Full thickness ● Adipose tissue ● Granulation ● Slough/eschar ● Tunneling Ⅳ ● Full thickness ● Muscle & bone ● Undermining ● Epibole DTI ● Deep tissue injury ● Intact skin ● Maroon/purple in color (looks like a bruise) ● Nonblanchable ● Stage 1 & 2 ( red = 1; purple = 2) Unstageable

● Stage 3 & 4 (under slough/eschar) ● Slough/eschar ◆ Causes difficulty in discerning extent of tissue damage ● Full thickness ❖ Arterial insufficiency vs. venous insufficiency ➢ Arterial insufficiency Chronic condition in which partial or total arterial occlusion deprives the lower extremities of oxygen and nutrients Pulses decreased or absent Pain may be present in feet/legs Ulcerations in area of toes, foot usually turns deep red when dependent Nails may be thick and rigid Pale shiny skin Venous insufficiency Includes disorders that result from increased venous pressure or valve damage of a vein wall Ulcerations usually around the ankle Pulses present but may be difficult to find because of edema Foot may be cyanotic when dependent Skin may have brownish discoloration Edema may be pitting CRITERIA ARTERIAL VENOUS Pain: Intermittent classification, pain at rest Painful Mechanism: Tissue ischemia Venous hypertension Pulses: Decreased or absent Normal, through may be difficult to feel Color: Pale, dusky red Normal or cyanotic on dependency, petechiae, brown pigmentation Temperature: Cool Normal Edema: Absent/mild Present Skin changes: Thin, shiny, atrophic skin, loss of hair over foot and toes, nails thickened Brown pigmentation around the ankle, dermatitis

Ulcerations: If present, toes or trauma on feet Develops at sides of ankle Gangrene: May develop Does not develop Medications ➢ Beta Blockers ■ -olol ■ Decreases blood pressure ■ Side effects ● Fatigue ● Weakness ● Erectile dysfunction ● Bradycardia ● HF ● Pulmonary edema ➢ Benzodiazepines ■ -zepam ■ CNS depressant; controls anxiety; sedative ➢ ACE Inhibitors ■ -pril ■ Decreases blood pressure; treats HF ➢ ARB Blockers ■ -artan ■ Decreases blood pressure ➢ Calcium Channel Blockers ■ -dipine ■ Decreases blood pressure; treats chest pain; treats migraines ➢ Thrombolytics ■ -ase/-plase ■ Dissolves blood clots ➢ Corticosteroids ■ -sone ■ Treats asthma, arthritis, cancer, autoimmune disorders ➢ Bronchodilators (Beta2-agonists) ■ -terol ■ Treats asthma, COPD ➢ DPP4 inhibitors ■ -gliptin

■ Decreases blood sugar ■ Sitagliptin ● Side effects ◆ Pancreatitis ◆ Anaphylaxis ◆ Angioedema ◆ Exfoliative skin conditions (Stevens-johnsons syndrome) ● Interactions ◆ Risk of hypoglycemia when also on insulin, glyburide, glipizide, glimepiride ➢ Incretin mimetics ■ -tide ■ Decreases blood sugar ➢ Leukotriene antagonists ■ -ast ■ Treats asthma & allergies ➢ Proton pump inhibitors (PPI’s) ■ -prazole ■ Treats GERD, peptic ulcers & H. pylori ■ Take 30 minutes before meals ➢ Sulfonylureas ■ -ide ■ Decreases blood sugar; treats type 2 diabetes ➢ Biguanide ■ Metformin ■ Decreases blood sugar Anticoagulant -arin Prevents blood clots Warfarin ● Side effects ◆ Calciphylaxis ◆ Bleeding ● Avoid foods high in vitamin K ◆ Broccoli ◆ Cauliflower ◆ Cabbage ◆ Brussel sprouts ◆ Kale

◆ Spinach Statins -statin Lipid-lowering medication; lowers cholesterol Avoid grapefruit when taking ● Atorvastatin ● Lovastatin ● Simvastatin Take at night Stool Softeners Docusate, Senna Prevents constipation Take at night NSAIDs Aspirin, ibuprofen, diclofenac Relieve pain, reduce inflammation, brings down temperature Loop Diuretics Bumetanide, furosemide, torsemide Increases flow of urinal removes sodium & chloride from body in urine Anticonvulsants -zepine/-in Decreases incidence/severity of seizures Gabapentin ● Side effects ◆ Suicidal thoughts ◆ Confusion ◆ Depression ◆ Dizziness ◆ Drowsiness ◆ Anaphylaxis ◆ Angioedema ◆ Multiorgan hypersensitivity reactions ● Take 2 hours after antacid (if you’re on one) ● Can interact with benzos Labs ➢ Na

135-145 mEq/L Cation in ECF Hyponatremia <135 mEq/L (severe <125) Symptoms: No Salt VAN Vomiting Anorexia Nausea Causes: 5 D’s Diuretics Diarrhea Dehydration Drains (NG, Fistulas) Diet Symptoms Headache/irritability, muscle twitching, tremors Assessments: Lab value, VS (BP, HR, Temp, Neuro/Mental Status Assess, I&O Interventions Restricted fluid intake, I&O monitoring, Monitor VS (administer Furosemide) Hypernatremia: >145 mEq/L Tachycardia Oliguria (dec. urinary output) BP (↑ then ↓) Seizures Symptoms: AFISH Anorexia Flush Irritable Sleepy Hot Common signs & symptoms: SALT Skin flushed Agitation Low-grade fever Thirst Causes Elderly with mental/physical impairments Acute infection

Diuretics Diabetes Decreased LOC Symptoms Neurologic impairment, restlessness, weakness, disorientation, delusion, hallucinations Assessments Lab value, VS (BP, HR, Temp), dehydration (skin turgor), I&O Interventions IV Fluid replacement (D5W), Monitor VS, I&O, skin breakdown, encourage oral intake K 3.5-5.1 mEq/L Intracellular Cation Hypokalemia <3. K+ deficit in ECF Symptoms - 5 L’s Lethargy Lethal cardiac arrhythmia Leg cramps Limp muscles Low, shallow respirators Symptoms: muscle weakness, fatigue, dysrhythmias Causes - GRADE GI loss Renal/kidney Alkalosis Diuretics Eat (lack of) Assessments VS, labs, I&O, reflexes Interventions VS monitoring, ECG, K administration, labs (Mag level) Hyperkalemia >5. Excess K+ in ECF (you typically die from having high K+) Symptoms - MURDER Muscle weakness Urine (oliguria/anuria)

Respiratory distress Decreased cardiac contractility EKG changes Reflexes (hyper/hypo) Symptoms: nerve conduction changes, paralysis, murder Causes - MIKA Meds ➢ Supplements, ACE inhibitors, Beta blockers, NSAIDs, K+ sparing diuretics Intake ➢ Excessive intake of bananas, spinach, yogurt, high K+ foods Kidney ➢ Impaired ability to secrete fluid Acidosis ➢ Result of an increase in acid components or an excessive loss of bicarbonate Assessments Labs, VS, I&O, reflexes Interventions VS monitoring, ECG, labs, meds CO 23 -29 mEq/L Symptoms: headache, lightheaded, change in LOC, cyanosis, pain during expiration/inspiration, barrel chested, hyperventilating, clubbing, cap refill > Heart: organs unable to perfuse d/t < O2 resp Lungs: SOB, hyperventilation, AKI, trauma, infection Labs: Na, CO2, GLU, Hgb, Hct, WBC Diagnosis Alterations in Oxygenation; ineffective airway clearance, ineffective breathing pattern, impaired gas exchange Outcome identification & planning Oxygenation problem The patient will: Demonstrate improved gas exchange in the lungs by an absence of cyanosis or chest pain Pulse oximetry <95% Exercise

Demonstrate self-care behaviors that provide relief from symptoms and prevent further cardiopulmonary problems. Implementing Promote/control coughing, suction, med administration, supplemental oxygen, manage chest tubes, artificial airways, CPR, teaching Teach Vaccination, smoking cessation/environment, nutrition, reducing anxiety, positioning, fluid intake, incentive spirometry, breathing techniques, coughing meds, chest physiotherapy oxygen, chest tube, CPR Meds Bronchodilators Liquefy or loosen thick secretions Reduce inflammation in airways Metered dose inhaler Nebulizer Dry powder inhaler Cl 95-105 Anion ECF Hyperchloremia Major causes Metabolic acidosis, head trauma, increased perspiration, decreased GFR Tachypnea, weakness, lethargy, decreased awareness, hypertension, decreased cardiac output, dysrhythmias, coma Hypochloremia Major causes Vomiting/diarrhea, drainage of GI tube, metabolic alkalosis, diuretics, burns Hyperexcitability, tetany, hyperactive DTRs, weakness, muscle cramps BUN 7-24 mg/dL Backs up Cr findings Formed in liver from ammonia

Excreted by kidneys Can be used to assess nutritional status Evaluates kidney function & aids in diagnosis of renal or liver disease Assessment of Hydration Effectiveness of dialysis Symptoms: seizures, altered LOC, swelling, chest pain, tachycardia, BP changes, dyspnea, crackles, oliguria/anuria Heart: cardiac enlargement, HF, HTN Lungs: COPD, respiratory failure Kidneys: AKI, CKD GI: meds, obesity Labs: Na, K, BUN, Cr, GLU, WBC, Mg, Phos Cells overfilled Cr 0.7-1.4 mg/dL Provides a more sensitive measure of renal damage than BUN levels Stress on kidneys Waste product from breakdown of tissue Assessment of Glomerular filtration Renal damage Symptoms: seizures, altered LOC, swelling, chest pain, tachycardia, BP changes, dyspnea, crackles, oliguria/anuria Heart: cardiac enlargement, HF, HTN Lungs: COPD, respiratory failure Kidneys: AKI, CKD GI: meds, obesity Labs: Na, K, BUN, Cr, GLU, WBC, Mg, Phos Cell overfilled GLU 60-110 mg/dL Symptoms Retinopathy, changes in LOC, dizziness, sweaty, tremors, HTN, palpitations, infection, renal failure, nephropathy, obesity, hunger, changes in urine, neuropathy Heart: blood vessel contraction, risk for CAD, HTN Lungs: reduced lung function, infection Kidneys: acute renal failure, nephropathy

GI: meds, diet/obesity Labs: Na, K, BUN, Cr, GLU Affected by different hormones Insulin Lowers glucose level Secreted by Islet cells of the pancreas Glucagon Increases glucose level by breaking down stored glucose Secreted by Islet cells of the pancreas Decreased levels of glucose to the brain (neuroglycopenia) Confusion Inability to concentrate Irritability Hallucinations Focal impairments Seizure Coma Death Causes to low glucose Medications Insulin, antidiabetic medications, beta-blockers Alcohol Sepsis, acute kidney injury Hormone deficiency Tumor/mass Malnourishment Family history Strenuous exercise Age Hyperglycemia ↑ Blood glucose levels Symptoms (3 P’s) Polyuria (frequent urination) Polydipsia (↑ thirst) Polyphagia (↑ hunger) Blurred vision Hypoglycemia ↓ Blood glucose levels Symptoms

Sweating, chills, clammy Shakiness Confusion Hct 35-45% Measures percentage by volume of RBCs in a whole blood sample 40% = 100mL sample of blood contains 40 mL of RBCs 5 below and above; 20% is a big deal General Solidifies Hgb (can mean more than one thing) Mean volume & hemoglobin concentration Packed-cell volume 60%: ¾ full (many RBCs; do not need to carry as much) Dehydration CO2 poisoning Living at high altitude 40%: RBC full (normal) 20%: RBC very full (half the amount of RBCs; trying to carry as much oxygen as possible); can’t carry enough affecting oxygenation Tachycardic: not getting enough O2, tries to compensate Pregnancy Anemia Heavy menstrual cycles Measures Polycythemia, anemia, dietary deficiencies Polycythemia (increase in RBC count) → ➢ Aspirin ➢ Bloodletting (Hct <45) Hydration status Hydration, IV fluids lowers RBCs Aid in calculation of erythrocytes Monitor response to treatments Determining need for blood transfusions Baseline before surgery/invasive procedures/treatments Hgb Males: 12-16 g/dL Females: 10-14 g/dL Protein in RBCs that carries oxygen to organs & tissues

Transports carbon dioxide from organs back to lungs How many RBCs do we have to carry O2 & CO2? Main indicator of general bleeding; specific/localized <8 big deal (.1 increments not a big deal) Measures Severity of anemia Polycythemia (too many RBC) Causes: ➢ Bone marrow produces too many RBCs → cancer ➢ Autoimmune disorder Response to therapy Baseline prior to surgery/invasive procedures/treatments Have we tried some sort of treatment like giving RBCs or iron? Have we done something to determine the reason why we don't have enough RBCs? Determine the underlying reason why our RBC is low/low production ➢ GI bleed → colonoscopy to determine where the bleed ➢ Hematoma ➢ Aneurysm Surgery is invasive (blood loss) ➢ Male patient hemoglobin is 10-11 before surgery and then after surgery it is 6-7 Distribution of oxygen to organs & tissues WBC 5,000 to 10,000/mm3 Respond to infection in the body Symptoms: febrile, change in LOC, confusion, dizziness, swollen lymph nodes, high HB (to compensate), sweaty, pain, BP changes (hypotension), body aches, oliguria/anuria (dehydrated), burning, increase RR, diarrhea Labs: Na (high, dehydrated), K (low, laxatives to get rid of K, 5Ds), BUN, Cr, GLU, WBC Heart: tachycardia, HF, MI Lungs: pneumonia (tachypnea) Kidneys: UTI