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Forensic Toxicology: Cannabis, Alcohol, Carbon Monoxide questions with solved solutions
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Toxicology - ANSWER>>Study of adverse effects of xenobiotics Toxicological evidence - ANSWER>>Collected post-autopsy Manifestations - ANSWER>>Effects based on measured concentration Chain of custody - ANSWER>>Tracking of sample collection Autopsy samples - ANSWER>>FB, HB, U, L, VH, SC Hospital samples - ANSWER>>Blood, urine, hair, serum/oral fluid Roadside samples - ANSWER>>Breath, serum/oral fluid Crime scene samples - ANSWER>>Miscellaneous Analytical methods - ANSWER>>Quantitative vs qualitative, nature of sample matrix Analytical performance - ANSWER>>Validation, accuracy, sensitivity, selectivity, precision, dynamic range Toxicological effects - ANSWER>>Expected effects at specific drug concentrations Case types - ANSWER>>Death investigations, sexual assault, homicide, impaired driving, administration of a noxious substance Pharmacology - ANSWER>>Study of drug effects on the body Pharmacokinetics - ANSWER>>Body's effect on drugs, absorption, distribution, metabolism, elimination
Absorption - ANSWER>>Process of drug entering the bloodstream Distribution - ANSWER>>Movement of drug throughout the body Metabolism - ANSWER>>Conversion of drug to new structure Elimination - ANSWER>>Removal of drug from the body Processes - ANSWER>>Absorption, distribution, metabolism, elimination Oral administration - ANSWER>>Absorption through stomach or small intestine Intranasal administration - ANSWER>>Absorption through nasal passage Intramuscular administration - ANSWER>>Injection into muscle Intravenous administration - ANSWER>>Injection into vein Transdermal administration - ANSWER>>Absorption through the skin Pharmacodynamics - ANSWER>>Effects of drugs on the body Drug-receptor binding - ANSWER>>Interaction between drug and receptor Agonist - ANSWER>>Binds to receptor and induces effects Antagonist - ANSWER>>Binds to receptor without inducing effects Partial agonist - ANSWER>>Induces lesser effect than conventional agonist Inverse agonist - ANSWER>>Induces opposite effects of conventional agonist Analytical plan - ANSWER>>Drug screening, targeted analysis, selectivity, sensitivity Gas chromatography - ANSWER>>Separation technique using gas as mobile phase