LAT TRAINING MANUAL UNIT 1 REVIEW EXAM (LAT 01-04) QUESTIONS AND ANSWERS LATEST, Exams of Advanced Education

Download LAT TRAINING MANUAL UNIT 1 REVIEW EXAM (LAT 01-04) QUESTIONS AND ANSWERS LATEST and more Exams Advanced Education in PDF only on Docsity! LAT TRAINING MANUAL UNIT 1 REVIEW EXAM (LAT 01-04) QUESTIONS AND ANSWERS LATEST. Suggested strategies - Correct Answer-We suggest that you time yourself when you take the review exam. Remember that you will have 2-1/2 hours to complete the 155 questions on the actual LAT certification exam. If you need to work on your speed in taking an exam, use the LAT review exams to help you develop this skill. You can retake this review exam (or any other review exam) as often as you need to. Each time you do, there will be different questions, and questions and answer choices will appear in a different order. The computer randomly selects questions from a large pool of questions so that each exam is unique. On average, you should answer about 1 question per minute in order to complete the examination within the time limit. Whistleblower protections are required by which regulation or guidelines? - Correct Answer-Animal Welfare Regulations Guide for the Care and Use of Laboratory Animals Animals from Class A dealers are known as: - Correct Answer-Purpose-bred The NIH is the primary funding agency for what type of research? - Correct Answer- Biomedical research Which of the following is one of the 3Rs? -Responsibility -Reduction -Resolve -Resolution - Correct Answer-Reduction AAALAC International accreditation is mandatory to ensure standards of animal care are met. T/F - Correct Answer-False. It is a voluntary process of self-evaluation and peer review. Euthanasia methods should result in a rapid loss of consciousness followed by cardiac or respiratory arrest and death. - Correct Answer-True In the context of biosafety, biosecurity means the protection of what? - Correct Answer- Microbial agents from loss, theft, diversion, or intentional misuse The ethical issues raised by an animal protocol should be discussed by the IACUC T/F - Correct Answer-True The essential elements of compliance are knowing and following the rules. T/F - Correct Answer-True Who should you inform of your concern for how an animal is being treated if you have not received a satisfactory response from your supervisor, the researcher, or veterinary personnel? - Correct Answer-IACUC If a GLP study is stopped, the data may be discarded. - Correct Answer-False. All the data that has been collected must be archived. A research institution is required to confer full authority to the attending veterinarian to ensure appropriate veterinary care. T/F - Correct Answer-True When a scientist completes a study, typically the results are published in a scientific journal. T/F - Correct Answer-True The continual review of ongoing animal studies by the IACUC is required by both the Animal Welfare Regulations and PHS Policy. T/F - Correct Answer-True Permits may be necessary from which of the following agencies to import or ship animals for research, depending on the animals' species and their health status? Centers for Disease Control and Prevention US Fish and Wildlife USDA Animal and Plant Health Inspection Service None of the Above All of the Above - Correct Answer-All of the Above What is the purpose of the "whistleblower" policy required by the Guide and the AWR? - Correct Answer-To protect personnel from discrimination or reprisal from reporting animal welfare concerns. Which term refers to assigning less complicated tasks to others in order to allow supervisors more time to get other work completed? Allotment Entrustment Delegation Allocation - Correct Answer-Delegation Which federal entities enforce Good Laboratory Practice regulations? - Correct Answer- Environmental Protection Agency Food and Drug Administration Who makes the decision of how to handle any serious deficiencies found during post- approval monitoring? - Correct Answer-IACUC In the Guide, which word is defined as indicating essential or imperative aspects for the proper humane care and use of lab animals? - Correct Answer-Must Research colleges and universities depend on grants to support their research programs. T/F - Correct Answer-True A cost recovery analysis for technical services offered by the vivarium is based on what? - Correct Answer-Revenue for the service compared to expenses for related supplies and labor The USDA inspects research facilities for compliance with which mandates? - Correct Answer-Guide for the Care and Use of Agricultural Animals in Research and Teaching USDA policies AVMA Guidelines for the Euthanasia of Animals After drugs are tested in animals, they may be approved by the Food and Drug Administration for use in humans. T/F - Correct Answer-False The Guide for the Care and Use of Agricultural Animals in Research and Teaching (Ag Guide) is a required mandate for which entities? - Correct Answer-AAALAC International for accreditation USDA for enforcement of the AWA Standard operating procedures (SOPs) are detailed documents that describe procedures to be performed and should be easily accessible by employees. T/F - Correct Answer-True The Guide for the Care and Use of Agricultural Animals in Research and Teaching (the Ag Guide) requires that institutions establish an occupational health program. T/F - Correct Answer-True Raw data for a GLP study may be entered first on a note pad and later transferred to a form sheet. T/F - Correct Answer-False. Raw data should be entered immediately on a form sheet developed for that purpose. Which element is NOT included in an institution's Animal Welfare Assurance to OLAW? Processes by which the IACUC reviews and inspects the program Description of personnel training program in animal care and use Square footage of each animal facility Background checks of key personnel in the program - Correct Answer-Background checks of key personnel in the program Institutional policies are optional guidance for best practices. T/F - Correct Answer- False The Guide includes construction guidelines for corridors, animal room doors, exterior windows, floors, drainage, walls and ceilings, HVAC, power and lighting, storage areas, noise control, vibration control, facilities for sanitizing materials, and environmental monitoring. T/F - Correct Answer-True Which mandate includes the full text of the US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training? - Correct Answer-Animal Welfare Regulations Animal Welfare Act PHS Policy on Humane Care and Use of Laboratory Animals Guide for The Care and Use of laboratory Animals Animals must always be treated ethically and humanely. T/F - Correct Answer-True The concept that states that people behave based on commonly held core values is called "philosophy." T/F - Correct Answer-False. It is called ethics. Animal housing per diem costs are typically paid with grant money. T/F - Correct Answer-True The Federal regulations cover companion animals but do not include husbandry or humane care of laboratory animals. T/F - Correct Answer-False Feed used for animals on study is a direct cost. T/F - Correct Answer-True What is the first step in planning a job? Establish goals. Analyze progress Prioritize tasks Adjust scheduling. - Correct Answer-Establish goals. An IACUC's semiannual review of the research program's policies and procedures includes which of the following? Husbandry practices Occupational health requirements Issues raised during the timeframe of the report Personnel training All of the Above - Correct Answer-ALL Compliance is the evaluation of the consequences of human actions on other humans, animals, and society. T/F - Correct Answer-False. Compliance is following the regulations and guidelines. Ethics evaluates the consequences of human actions on humans, animals, and society. What step is important to do before you start on a task? - Correct Answer-Locate all the resources needed for the task. Grant funding for animal research may be obtained from which organization/s? US Department of Veterans Affairs (VA) US Department of Defense (DOD) National Science Foundation (NSF) American Heart Association (AHA) All of the Above - Correct Answer-All Why does the Office of Laboratory Animal Welfare (OLAW) inspect research facilities? - Correct Answer-Routine inspections of selected institutions Potential noncompliance with the PHS Policy Typically, at least 50% of submitted proposals for grant money are funded. T/F - Correct Answer-False How often must the controlled substance inventory list be updated? - Correct Answer- Every 2 years The AWA and the PHS Policy cover the exact same species of animals. - Correct Answer-False. While there is some overlap, there are differences between the two in terms of animals covered. Before a new drug is tested on human subjects, the drug is tested on animals in a phase that is called __________ testing. - Correct Answer-preclinical If a researcher substitutes an animal with a lower sentient species, which of the 3Rs is being applied? - Correct Answer-Replacement Which entity evaluates an institution's animal research program based on semiannual reviews, annual reports, and three-year site visits? - Correct Answer-AAALAC International What method is used to distribute shared costs, such as PPE or cage wash labor, across each species? - Correct Answer-Percentage of effort, census, or use for that species Although not a regulation, the Guide for the Care and Use of Laboratory Animals must be followed for research with animals covered by which mandate? - Correct Answer- Public Health Service (PHS) The full name for the acronym IACUC is the Institutional Animal Care and Use Council. T/F - Correct Answer-False. The full name for the acronym IACUC is the Institutional Animal Care and Use Committee. Policy violations should be reported as noncompliance. Policies help employees make sound decisions in program activities. Policies protect employees and institutional resources. Policies override regulatory requirements. - Correct Answer-Policies override regulatory requirements. If an animal with a health condition such as diabetes is needed for a study, who can grant an exception to the requirement for a health certificate? - Correct Answer-USDA Which of the following is NOT a method for the technician to support the ethical treatment of animals? Determining if an animal has reached the humane endpoint Using appropriate restraint techniques Demonstrating respect and compassion for the animals Reporting issues to a supervisor or veterinarian - Correct Answer-Determining if an animal has reached the humane endpoint Which entity in AAALAC International approves an institution's application for accreditation? - Correct Answer-Council on Accreditation Which of the following is NOT an example of raw data for a GLP study? Lab notes Health certificate Facility logs Biological specimens - Correct Answer-Health certificate Which of the following is NOT a GLP requirement? Test articles must be clearly labeled. Animals must be identified accurately. New animals must be quarantined. Studies must be kept in separate rooms. - Correct Answer-Studies must be kept in separate rooms. Which state passed legislation starting in 2020 that prohibits the sale of cosmetic products and ingredients that have been tested on animals? - Correct Answer-California What is a grant application used to request? - Correct Answer-Research money In a GLP animal study, test system refers to what? - Correct Answer-Animal model In the Guide, which word is defined as indicating strong recommendations for the proper humane care and use of lab animals? - Correct Answer-Should A document that outlines the steps required to clean an animal room is called a: - Correct Answer-standard operating procedure. According to the GLPs, a _______ includes the animals or other entity that is administered a substance. - Correct Answer-Test system Which statement is TRUE regarding a personnel training program in animal care and use? All personnel should complete the same training program before starting their jobs. Training may be offered to personnel with no contact with animals to demonstrate animals are being appropriately handled. Visiting scientists are typically exempted from the training program requirements. Occupational health and safety training may be offered for cagewash personnel only. - Correct Answer-Training may be offered to personnel with no contact with animals to demonstrate animals are being appropriately handled. A health certificate is NOT required for which animal species shipped interstate in the US? Macaque Dog Cat Sprague Dawley rat - Correct Answer-Sprague Dawley rat What does the Guide acknowledge as determining the necessity for various functional areas in the physical plant of a research program? - Correct Answer-Scope and type of research conducted Research institutions must file a(n) __________ __________ Assurance with the Office of Laboratory Animal Welfare to commit to compliance with PHS Policy. - Correct Answer-Animal Welfare To keep controlled substances on site, an animal facility must have what from the Drug Enforcement Administration (DEA)? - Correct Answer-License What is the goal of ethical decision making in an animal research program? - Correct Answer-To balance the consideration of all important factors in the decision. What statement is TRUE about compliance and ethics? Ethics is obeying the rules from laws, regulations, and guidelines. Resolving ethical questions often requires a team approach. Compliance is the systematic process to balance ethical costs and benefits. Ethics and compliance mean the same thing. - Correct Answer-Resolving ethical questions often requires a team approach. Guidance for controlling laboratory animal allergy can be found in which document? - Correct Answer-Occupational Health and Safety in the Care and Use of Research Animals Which step is the most productive way to organize tasks? - Correct Answer-Schedule tasks in order of importance and deadlines Which statement about GLP animal studies is FALSE? All housing areas should be kept clean and sanitized regularly. New animals must be used immediately as received from the vendor. Contaminant levels of feed and water should be analyzed and documented. Animals on study must be identified accurately. - Correct Answer-New animals must be used immediately as received from the vendor. What is the purpose of the "whistleblower" policy required by the Guide and the AWR? - Correct Answer-To protect personnel from discrimination or reprisal from reporting animal welfare concerns If an animal was used in experiments, teaching, research, experiments, or tests causing pain or distress to the animals, for which appropriate anesthetic, analgesic, or tranquilizing drugs were used, which United States Department of Agriculture (USDA) pain category would this describe? - Correct Answer-D Who must approve an animal use protocol before a study that involves animals can begin? - Correct Answer-Institutional Animal Care and Use Committee (IACUC) What determines how long GLP archives of data must be stored? - Correct Answer- Research or marketing permit A GLP testing facility for animal studies must have the following EXCEPT? Records of all testing, calibrating, and inspections Storage areas of feed, bedding, supplies, and equipment Procedures for collecting and handling wastes Areas for computing data analysis for a study - Correct Answer-Areas for computing data analysis for a study Which category best describes the animal species covered by the PHS Policy? - Correct Answer-Vertebrates Which statement regarding a decentralized management program is FALSE? Each department that uses animals maintains its own facility. Each department that uses animals is managed by one supervising department. Each department that uses animals has its own operating budget. Each department that uses animals is responsible for getting its own supplies. - Correct Answer-Each department that uses animals is managed by one supervising department. How long does the United States Department of Agriculture (USDA) require that protocol records be retained? - Correct Answer-3 years