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Microbiology and Immunology Concepts, Exams of Microbiology

A wide range of topics in microbiology and immunology, including infectious diseases, diagnostic tests, and the classification of microorganisms. It provides detailed information on various pathogens, their associated diseases, and the corresponding laboratory tests used for identification and diagnosis. The document delves into the characteristics of different types of microbes, their growth requirements, and the interactions between microbes and their hosts. It also covers fundamental concepts in immunology, such as the different types of immunity, hypersensitivity reactions, and the mechanisms of the complement system. This comprehensive resource can be valuable for students and professionals in the fields of medicine, biology, and public health, as it offers a thorough understanding of the complex relationships between microbes, the human body, and the immune system.

Typology: Exams

2024/2025

Available from 10/15/2024

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Download Microbiology and Immunology Concepts and more Exams Microbiology in PDF only on Docsity!

IRENE GOLD MICROBIOLOGY BOARDS

FINAL EXAM NEWEST ACTUAL EXAM COMPLETE

400 QUESTIONS AND CORRECT DETAILED

ANSWERS (VERIFIED ANSWERS) |ALREADY

GRADED A+

Measles family? - ANSWERParamyxoviridae Mumps family? - ANSWERParamyxoviridae RSV family? - ANSWERParamyxoviridae Influenza family? - ANSWEROrthomyxoviridae Rabies family? - ANSWERRhabdoviridae Ebola family? - ANSWERFiloviridae Hantavirus family? - ANSWERBunyaviridae Rotavirus family? - ANSWERReoviridae Rhinovirus family? - ANSWERPicornaviridae Poliovirus family? - ANSWERPicornaviridae ECHO virus family? - ANSWERPicornaviridae Coxsackie virus family? - ANSWERPicornaviridae Rubella family? - ANSWERTogaviridae W/E equine encephalitis family? - ANSWERTogaviridae Dengue virus family? - ANSWERFlaviviridae Yellow fever virus? - ANSWERFlaviviridae

St. Louis encephalitis family? - ANSWERFlaviviridae Norwalk virus family? - ANSWERCaliciviridae Secretory Ab found in mucous membranes. Transferred through breast milk - ANSWERIgA Ab that helps IgG - ANSWERIgD Ab that increases in Hodgkin's - ANSWERIgE Most numerous Ab. Transferred in utero. Anamnestic response. First to increase in repeat exposure - ANSWERIgG Largest and heaviest Ab. Pentamer. Non specific. First to increase in initial exposure - ANSWERIgM Lymphocyte activating factor made by macrophages for brain and nervous tissue - ANSWERIL- 1 T cell growth factor made by CD4 cells - ANSWERIL- 2 IL made by bone marrow for blood and lymph - ANSWERIL- 3 Major histocompatibility complex (MHC) 1 is recognized by what cells - ANSWERT cells and B cells Major histocompatibility complex (MHC 2) is recognized by what cells - ANSWERB cells only Gram positive organisms - ANSWERBacillus Listeria monocytogenes Clostridium Cornybacterium diptheriae Staph Strep (BLCCSS) Staph aureus diseases - ANSWERScalded skin syndrome Toxic shock Osteomyelitis Impetigo (MCC) Carbuncles (STOIC) Strep pyogens diseases - ANSWERStrep throat

Erysipelas (superficial cellulitis) Rheumatic fever Glomerulonephritis Impetigo (2nd MCC) Scarlet fever (SERGIS) What presents with strawberry tongue - ANSWERScarlet fever "Saint Anthony's fire" - ANSWERErysipelas Jones criteria for rheumatic fever - ANSWERCarditis (MacCallum patch in posterior left atrium) Syndenham's chorea Subcutaneous nodule Erythema marginatum Migratory polyarthritis Function of complement system? - ANSWEREnhances phagocytosis Classical and alternate complement pathways meet at? - ANSWERC3B Complement system membrane attack complex formation takes place at - ANSWERC5b- 9 Aschoff bodies are associated with - ANSWERRheumatic fever Extensive Aschoff bodies - ANSWERMcCallums patch Babes Ernst granules are associated with - ANSWERDiphtheria Councilman cells are associated with - ANSWERViral hepatitis Downey cells are associated with - ANSWERMononucleosis Epithelioid histiocytes are associated with - ANSWERTB Calcium jail around mycobacterium - ANSWERGhon complex Guarneri bodies are associated with - ANSWERSmall pox (variola) Gummas are associated with - ANSWERTertiary syphilis Koplik spots are associated with - ANSWERMeasles Old age pigment - ANSWERLipofuscin

Build up of lipofuscin in organs - ANSWERBrown's atrophy Lewy bodies are associated with - ANSWERParkinson's Mallory bodies are associated with - ANSWERHepatitis/alcoholism Negri bodies are associated with - ANSWERRabies Reed Sternberg cells are associated with - ANSWERHodgkin's Russell bodies are associated with - ANSWERChronic inflammation, malignancy, multiple myeloma Antibody against a toxin - ANSWERAntitoxin Immunity type: disease exposure and body reaction - ANSWERNatural active Immunity type: injection of attenuated organism - ANSWERArtificial active Tetanus toxoid injection is which type of immunity - ANSWERArtificial active Immunity type: Ab from mother to infant - ANSWERNatural passive Ab transferred in utero - ANSWERIgG Ab transferred through breast milk - ANSWERIgA Immunity type: injection of preformed Ab - ANSWERArtificial passive Tetanus antitoxin injection is which type of immunity - ANSWERArtificial passive T/F: tetanus antitoxin can cross BBB - ANSWERF Toxin from lipopolysaccharide later of cell - ANSWEREndotoxin Are endotoxins heat stable? - ANSWERYes Do gram+ or gram- organisms produce endotoxins - ANSWERGram- Toxin that affects the intestines - ANSWEREnterotoxin Toxin from cell wast products - ANSWERExotoxin Are exotoxins heat stabile - ANSWERNo - heat labile

Inanimate object is vector - ANSWERFomite Partial antigen. Does not stimulate immune response - ANSWERHapten Toxin that affects the nervous system - ANSWERNeurotoxin Function of opsonin? - ANSWEREnhance phagocytosis Acellular protein that denatures other proteins - ANSWERPrion Inactivated toxin - ANSWERToxoid Hypersensitivity type 1 - ANSWERAnaphylactic/immediate Hypersensitivity reaction type: asthma, allergy, bee sting, hay fever - ANSWERType 1 Hypersensitivity with IgE, mast cells, basophils - ANSWERType 1 Hypersensitivity type 2 - ANSWERCytotoxic Hypersensitivity reaction type: min-hours. Goodpasteur's, erythroblastosis fetalis, blood transfusions, myasthenia gravis, Grave's - ANSWERType 2 Hypersensitivity with IgG. Antigen and antibody - ANSWERType 2 Hypersensitivity type 3 - ANSWERImmune-complex mediated Hypersensitivity reaction type: 3-10 hours. Glomerulonephritis, lupus, RA. Arthus reaction (local necrosis). Serum sickness (systemic) - ANSWERType 3 Hypersensitivity with IgG and complement. Antigen and Ab and complement - ANSWERType 3 Hypersensitivity type 4 - ANSWERDelayed/cell-mediated Hypersensitivity reaction type: 48 hours. TB, contact dermatitis, transplant rejection - ANSWERType 4 Hypersensitivity with T cells and lymphocytes - ANSWERType 4 Microbe that eats inorganic material - ANSWERAutotroph Microbe that eats organic material - ANSWERHeterotroph Microbe that eats dead/decaying material - ANSWERSaprophyte

Microbe that eats off living organisms - ANSWERParasite Microbe that prefers oxygen - ANSWERFacultative aerobe Microbe that prefers no oxygen - ANSWERFacultative anaerobe Microbe that requires oxygen - ANSWERObligate aerobe Microbe that requires no oxygen - ANSWERObligate anaerobe Microbe that lives with reduced oxygen - ANSWERMicroaerophile What type of microbe is grown in candle jar culture - ANSWERMicroaerophile 2 populations living together - one or both benefit - ANSWERSymbiosis 2 populations living together - both benefit - ANSWERMutualism 2 populations living together - both benefit and accomplish what neither can do alone - ANSWERSynergism 2 populations living together - one benefits and the other is unaffected - ANSWERCommensalism Transfer of disease from animal to human - ANSWERZoonosis Single flagella on one pole - ANSWERMonotrichus Multiple flagella on one pole - ANSWERLophotrichus Flagella on both poles - ANSWERAmphitrichus Flagella all the way around - ANSWERPeritrichus Test for carcinogenicity/mutagenicity - ANSWERAmes test Ames test uses what pathogen - ANSWERSalmonella typhimurium Test for anthrax - ANSWERAscholi test Test for rheumatic fever (for strep pyogens Ab) - ANSWERASO titer Test for % of butterfat in milk - ANSWERBabcock test Test for pneumococci vs alpha hemolytic strep viridans - ANSWERBile solubility test

Best test for water pollution - ANSWERBOD (biological oxygen demand) Complement fixation test - ANSWERBordet Gengou phenomenon Test to differentiate staph from strep - ANSWERCatalase (staph+) Culture for growing viruses (obligate intracellular parasites) - ANSWERChick embryo or tissue culture Agar for growing gonorrhea - ANSWERChocolate agar (Thayer Martin agar/Heated blood agar) Test to differentiate staph aureus from other staph - ANSWERCoagulase (aureus+) Test for E. Coli in water - ANSWERColliform test Test for hemolysis - ANSWERComplement fixation test Test for RBC antigens, hemolytic anemia, erythroblastosis fetalis, Rh factor - ANSWERCoombs test Test for scarlet fever - ANSWERDick test Test for protozoa - ANSWERGiemsa stain Test for seronegative arthritides (PEAR) - ANSWERHLA B Test for AIDS - ANSWERHLA DR5/CD EILSA test specifically tests.. - ANSWERDNA Western blot test specifically tests.. - ANSWERProtein Test for staph - ANSWERMannitol salt CSF test for meningitis would show? - ANSWERLow glucose Heterophile agglutination test for mononucleosis - ANSWERPaul Bunnel test Test to determine if all phosphatase enzyme is destroyed in milk pasteurization - ANSWERPhosphatase test Test for swelling of capsule of strep pneumoniae - ANSWERQuellung reaction test Test for fungi - ANSWERSabouraud agar

Test for immunity to diphtheria - ANSWERSchick test Test for antitoxin reaction to scarlet fever - ANSWERSchultz-Carlton reaction Serology test that is positive for all Rickettsia except Coxiella burnetti (Q fever) - ANSWERWeil Felix test What antigen is used in Weil Felix test - ANSWERProteus vulgaris Test for typhoid fever - ANSWERWidal test Test for herpes zoster/simplex, varicella - ANSWERTzank test 6 syphilis tests - ANSWERKline test Kahn test Washerman test TPI VDRL Darkfield test 5 TB tests - ANSWERMantoux/Tine/skin prick test PPD (purified protein derivative) Delayed hypersensitivity test (type 4) Ziehl Nielsen staining (acid fast organisms) Chest xray T/F: all mycobacterium are acid fast - ANSWERT 4 mononucleosis tests - ANSWERHeterophile Ab test Paul Bunnel test Downey cell Monospot Pasteurization method: 145F for 30 min - ANSWERHolding/batch method Pasteurization method: 161F for 15 sec - ANSWERFlash/continuous Pasteurization method: 191F for 2 - 5 sec - ANSWERUltrahigh Pasteurization method: 274F for 15 min - ANSWERSterilization/autoclave Pasteurization method: steam heat under pressure that denatures membranes - ANSWERSterilization/autoclave Salk or rabies vaccines are examples of what vaccination type - ANSWERInactivated

Tetanus or botulism vaccines are examples of what vaccination type - ANSWERToxoid Measles, mumps, rubella, and Sabin vaccines are examples of what vaccination type - ANSWERLive attenuated Measles and mumps vaccines are manufactured from - ANSWERChick embryo Rubella, rabies, and hep A vaccines are manufactured from - ANSWERHuman diploid cells Polio vaccine is manufactured from - ANSWERMonkey kidney tissue Ascending demyelination of PNS that can be acquired after flu vaccine or infection - ANSWERGillian-Barre (post-infectious polyradiculopathy) Case study type that identifies risk factors - ANSWERCase control Case study type that eliminates placebo effect - ANSWERDouble blind Pus color for Pseudomonas aeruginosa (open burn infection) - ANSWERBlue/green Pus color for Serratia marcenscens - ANSWERRed Pus color for Chlamydia - ANSWERWhite Pus color for staph aureus - ANSWERYellow Pus color for gonorrhea - ANSWERYellow/green Drug used to fix gross specimens - ANSWERFormaldehyde Drug used for pre-op disinfectant - ANSWERIodine Drug used for gram+ organisms. Inhibits cell wall synthesis - ANSWERPenicillin Drug that used to be used for newborn's eyes to prevent ophthalmia neonatorum (Gonorrhea) - ANSWERSilver nitrate Drug that replaced silver nitrate for newborn's eyes - ANSWERErythromycin Drug used for MRSA treatmetn - ANSWERVancomycin MRSA stands for - ANSWERMethycilline resistant staph aureus Drug for gram- organisms. Inhibits protein synthesis - ANSWERStreptomyecin

Drug for gram- organisms. Competes with PABA - ANSWERSulfa Drug that inhibits protein synthesis in gram+ and gram- organisms. Turns teeth gray/yellow/brown - ANSWERTetracycline Person who developed humoral/phagocytic theory of immune response - ANSWERBurnet/Metchinkoff Person who discovered bacteriophage (altered virus) - ANSWERFelix D'Herelle Person who developed magic bullet sulfa drugs. First syphilis treatment - ANSWEREhlich Person who discovered penicillin - ANSWERFlemming Person who discovered the first virus (tobacco mosaic virus) - ANSWERIwanowski Person who developed the smallpox vaccine - ANSWERJenner Person who proved that bacteria causes disease and formulated the anthrax vaccine - ANSWERKoch Person who classified streptococcus - ANSWERRebecca Lancefield Person who developed the first microscope - ANSWERLeeuwenhoek Person who developed antisepsis using carbolic acid to sterilize surgical instruments - ANSWERLister Father of pathology/germ theory. Disproved spontaneous generation. Developed rabies vaccine - ANSWERPasteur Pasteur pasteurized what before milk? - ANSWERWine Person who discovered prions - ANSWERStanley Pyusner Person who discovered yellow fever - ANSWERWalter Reed Person who developed oral live polio vaccine - ANSWERSabin Person who developed first polio vaccine (dead injection) - ANSWERSalk Person who came up with washing hands before delivering a baby and reduced puerperal fever/childbed fever - ANSWERSemmelweiss Description of morphology of agar plate colonies. DHMORS - ANSWERD - dwarf

H - spreading M - mucoid capsule O - compact (O vs. H) R - rough S - smooth Koch's 4 postulates - ANSWER1. Find microorganism in people with disease

  1. Isolate and grow it in a culture
  2. Should cause disease in healthy individual when introduced
  3. Reisolate microorganism from inoculated people Acid fast stain is used to test for - ANSWERMycobacterium Blood agar is used to categorize - ANSWERStreptococcus Alpha hemolysis in a blood agar will show - ANSWERPartial hemolysis - green ring Strep pneumoniae and strep viridans are examples of which hemolysis type - ANSWERAlpha What pathogen causes subacute bacterial endocarditis secondary to rheumatic fever - ANSWERStrep viridans Beta hemolysis in a blood agar will show - ANSWERComplete hemolysis - clear ring Strep pyogenes is an example of which hemolysis type - ANSWERBeta Gamma hemolysis in a blood agar will show - ANSWERNothing - no change Strep mutants is an example of which hemolysis type - ANSWERGamma Giemsa stain is used for - ANSWERProtozoa Gram stain procedure - ANSWERPrimary - crystal violet or methylene blue Fixer - iodine Decolorizer - acetone or ethyl alcohol Counterstain - saffarin (red/pink) Mannitol salt is used for - ANSWERStaphylococcus Term for plasmid DNA transfer via sex pilus - ANSWERConjugation Term for bacteriophage transferring genetic material between bacteria - ANSWERTransduction Term for direct uptake of free DNA for cell reproduction - ANSWERTransformation

CDC produces.. - ANSWERStatistics Agency that monitors soil/air/water quality - ANSWEREPA Agency that controls FDA, CDC, USPHS - ANSWERHHS NIH produces.. - ANSWERResearch Agency responsible for milk and milk products - ANSWERUSDA Leading causes of death for infants (2) - ANSWER1. Congenital malformations

  1. Prematurity Leading causes of death for US adults (5) - ANSWER1. Heart disease
  2. Cancer
  3. Stroke
  4. Respiratory infection
  5. Accidents Leading causes of death for adults worldwide (2) - ANSWER1. TB
  6. Malaria Water purification steps (8) - ANSWER1. Filtration
  7. Flocculation (aluminum trichloride)
  8. Sedimentation
  9. Sludge digestion (add anaerobic bacteria)
  10. Sand filtration (removes bacteria)
  11. Aeration (decreases BOD)
  12. Chlorination
  13. Fluoridation (optional) A tapeworm is a type of.. - ANSWERFlatworm A fluke is a type of.. - ANSWERFlatworm Common name for tapeworm - ANSWERCestode Common name for roundworm - ANSWERNematode Common name for fluke - ANSWERTrematode Worm with flat ovoid body - ANSWERFluke/trematode Worm with cylindrical unsegmented body - ANSWERRoundworm/nematode

Worm with long ribbon-like body - ANSWERTapeworm/cestode Term for the head of a tapeworm - ANSWERScolex Term for the body of a tapeworm - ANSWERProglottids Dwarf tapeworm spread via mouth that causes diarrhea - ANSWERHymenolepis nana (tapeworm) Tapeworm in uncooked beef - ANSWERTaenia saginata Tapeworm in uncooked pork that causes larval cysts in liver, eye, brain - ANSWERTaenia solium Tapeworm in uncooked fish (MC yellow fin tuna) that causes pernicious anemia - ANSWERDiphyllobothrium latum Tapeworm in dog feces that causes hydatid cysts in liver and lungs - ANSWEREchinococcus granulosus Blood fluke in snails and water that causes swimmer's itch and inhabits liver - ANSWERShistosoma japonicum MCC of death by helminth worldwide - ANSWERShistosoma japonicum Intestinal fluke in aquatic plants from snail feces - ANSWERFasciolopsis buski Liver fluke in raw fish - ANSWERClonorchis sinensis Liver fluke in aquatic plants - ANSWERFasciolopsis hepatica Pulmonary fluke in crayfish - ANSWERParagonimus westermani Roundworm spread via oral/fecal that causes colicky pain and lives in small intestine - ANSWERAscaris lumbricoides MC roundworm - ANSWERAscaris lumbricoides MC helminthic infection worldwide - ANSWERAscaris lumbricoides Roundworm spread via mosquitoes that causes elephantitis - ANSWERWuchereria bancrofti (filiariasis type) Roundworm in feces contaminated soil. Hookworm - ANSWERNecator americanus/ancylostoma duodenale

MC hookworm in US - ANSWERNecator americanus/ancylostoma duodenale Roundworm spread via oral/fecal that causes nocturnal anal itching. Dx with scotch tape test. Pinworm/threadworm - ANSWEREnterobius vermicularis MC helminth in US - ANSWEREnterobius vermicularis Roundworm spread via flies that causes river blindness in Africa - ANSWEROnchocerca volvulus Roundworm spread via flies. River eye worm in africa - ANSWERLoa loa Roundworm in raw pork that lives in striated muscle, intercostal, and diaphragm. Dx on xray - ANSWERTrichonella spiralis Roundworm spread via oral/fecal that causes weight loss. Whipworm - ANSWERTrichuris trichura Subunit of protein coat/capsid of virus particle - ANSWERCapsomere The viral envelope is made up of a - ANSWERTrilamina lipid membrane SsRNA. Infects plants - ANSWERviroid T/F: a virus can contain DNA, RNA, or both - ANSWERF - can only contain DNA or RNA - NOT BOTH Viruses are most commonly transmitted via which bodily system - ANSWERRespiratory Exceptions include arboviruses, AIDS, polio (oral/fecal), rabies, warts, hepatitis Which type of herpes simplex causes fever blister or cold sores and lives in trigeminal ganglion - ANSWERType 1 What causes shingles - ANSWERHerpes zoster What virus causes pink cauliflower lesions on female genitalia - ANSWERMolluscum contagiosum German measles/3 day measles. Causes limb malformation - ANSWERRubella virus Red measles. Causes Koplik spots. Cough, coryza, conjunctivitis - ANSWERRubeola virus What virus causes cow pox - ANSWERVaccinia What virus causes a maculopapularvesicular rash - ANSWERVaricella - chicken pox

What virus causes small pox - > Guarneri bodies - ANSWERVariola What virus causes childhood dysentery - hand/foot/mouth disease - ANSWERCoxsackie virus B Echo virus causes? - ANSWERSkin rash, heart disease, enteric reaction Hantavirus is spread via - ANSWERRodents Virus spread via oral/fecal that affects anterior horn - ANSWERPolio Virus that causes conjunctivitis and pharyngitis - ANSWERAdenovirus Virus with antigenic shift (big mutation) or drift (small mutation) - ANSWERInfluenza What virus causes mumps (parotiditis) and can lead to Bell's palsy - ANSWERSidomegalic paramyxoid virus What virus causes croup and bronchiolitis usually in children - ANSWERRSV What virus causes birth defects and disseminated disease in AIDS patients - ANSWERCMV Bullet shaped virus that causes Negri bodies in brain - ANSWERRabies Negative reaction to aspirin taken for viral infection. Leads to fatty liver and encephalopathy - ANSWERReyes syndrome MC fungal infection in AIDS - ANSWERPneumocystitis carinii MCC of AIDS death - ANSWERPneumocystitis carinii MC parasitic infection in AIDS - ANSWERToxoplasmosis How is toxoplasmosis spread - ANSWERCat feces MCC of death by cancer in AIDS - ANSWERKaposi sarcoma Opportunistic AIDS infection that causes mucousy diarrhea - ANSWERGiardia lamblia MC protozoal infection in AIDS - ANSWERToxoplasmosis Hepatitis spread via oral/fecal - ANSWERHep A

Hepatitis spread via sex/IV drug use and causes liver cancer. Only DNA virus. Most lethal in acute phase. Endemic in Asia - ANSWERHep B Hepatitis spread via tattoos/blood transfusions and causes liver cancer - ANSWERHep C Hepatitis that co-infects with Hep B - ANSWERHep D Are equine encephalitis diseases group A or B arbovirus? - ANSWERA Is yellow fever group A or B arbovirus? - ANSWERB Is dengue fever group A or B arbovirus? - ANSWERB Common name for eastern equine encephalitis - ANSWERWest Nile virus Vector for yellow fever - ANSWERAedes agypti mosquito First sign of dengue fever - ANSWERArthralgia What arbovirus causes breakbone fever/bone crusher disease - ANSWERDengue fever Arbo-bacteria spread via rat flea (xenopsylla cheopis) that causes neck and axillary lymph node enlargement. Death by asphyxiation - ANSWERBubonic plague Pathogen that causes bubonic plague - ANSWERYersinia/pasteruella pestis Arbo-bacteria spread via rabbits - ANSWERTuleremia Pathogen that causes tuleremia - ANSWERFrancisella tularensis Foodborne bacteria that causes floppy baby syndrome. Diploplia - > death - ANSWERClostridium botulinum What is added to meat to prevent botulism - ANSWERNitrates MCC of gastritis, diarrhea, and food poisoning. Abdominal pain, blood/pus in stool, fever

  • ANSWERCampylobactor jejuni Bacteria in deli meats and soft cheeses - ANSWERListeria monocytogenes Bacteria in eggs and poultry. Infection causes fever - ANSWERSalmonella entrides Bacteria in creams and custards. Heat stabile toxin - ANSWERStaph aureus

Bacteria that causes rose colored spots on abdomen and hides in GB and ileum Peyer's patches. Dx with Widal test - ANSWERSalmonella typhi - typhoid fever Water borne bacteria also in milk that causes Bang's disease. Undulant fever and spontaneous abortions in cattle - ANSWERBrucella abortus Water borne bacteria that causes rice water stools and vomiting - ANSWERVibrio cholera Water and soil borne bacteria that causes dysentery - ANSWERShigella Pathogen that causes traveler's diarrhea/Montezuma's revenge - ANSWEREnterotoxigenic E. Coli Enterohemorrhagic E. Coli causes - ANSWERHamburger's disease Soil borne bacteria spread via spore inhalation from animals - ANSWERBacillus anthracosis (gram+) Soil borne bacteria that causes lockjaw/trismus by inhibiting GABA and glycine (blocking inhibitory NTs) - ANSWERClostridium tetani Soil borne bacteria that causes gas gangrene - ANSWERClostridium perfingings/welchi Causes of otitis media (2) - ANSWER1. Hemophilus influenza

  1. Strep pneumoniae Causes of otitis external (2) - ANSWER1. E. Coli
  2. Pseudomonas aeruginosa Spirochete in water that causes Weil's syndrome (hemorrhagic jaundice) - ANSWERLeptospira interrobang/ictohemorrhagica - Leptospirosis Spirchete spread via deer tick/lxodes scapular that causes erythema chronicum migricans/bull's eye rash - ANSWERBorrelia burgdorferi - Lyme's disease Spirochete spread via ticks/lice/rabbits that causes a relapsing fever - ANSWERBorrelia recurrentis Spirochete STD that causes syphilis - ANSWERTreponema pallidum Spirochete spread via skin contact that causes non-venereal syphilis. Tropical infection of skin/bone/joint - ANSWERTreponema pertenue - Yaws What test differentiates treponema pallidum and pertenue - ANSWERDark field microscopy

Childhood dysentery is caused by - ANSWERCoxsackie virus B Bacterial dysentery is caused by - ANSWERShigella Amoebic dysentery is caused by - ANSWEREntamoeba histolytica Bacterial shape: "many shapes" - ANSWERPleomorphic What shape is strep - ANSWERLinear A cluster of bacteria - ANSWERStaph Comma shaped bacteria - ANSWERVibrio Bacterial virulence factor for B hemolytic strep that dissolves clots - ANSWERStreptokinase Bacterial virulence factor for staph that catalysts formation of fibrin from fibrinogen - ANSWERCoagulase Bacterial virulence factor for staph that breaks down RBCS - ANSWERHemolysin Bacterial virulence factor exotoxin for staph or strep that kills WBCs - ANSWERLeukocidin Bacterial virulence factor for staph, strep, or clostridia that breaks down tissue "cement" of hyaluronic acid and facilitates dissemination - ANSWERHyaluronidase Bacteria that grow at 15C or lower - ANSWERPsychophilic Bacteria that grow at 25-40C (optimal is 37C - human temp) - ANSWERMesophilic Type of bacteria that are killed by fever - ANSWERMesophilic Bacteria that grow at 45C or above - ANSWERThermophilic MCC of meningitis in newborns (2) - ANSWER1. E. Coli

  1. Listeria MCC of meningitis in children (2) - ANSWER1. Strep pneumoniae
  2. Neisseria meningitides Which meningitis is the only that presents with a rash - ANSWERNeisseria meningitides MCC of meningitis in adults - ANSWERStrep pneumoniae

Most lethal meningitis that causes primary amoebic meningoencephalitis - ANSWERNaegleria fowleri Protozoa in food and water that causes amoebic dysentery (mild diarrhea). Cyst is infective - ANSWEREntamoeba histolytica - Amebiasis Protozoa that is in stream water and causes flatulence, poor absorption, mucousy diarrhea. Cyst is infective - ANSWERGiardia lamblia - Giardiasis (beaver fever) Protozoa spread by sandflies. Viscerotropic - ANSWERLeishmania donovani - Kala- Azar disease/Leishmaniasis Protozoa spread by female anopheles mosquito. Causes anemia and chronic splenomegaly - ANSWERPlasmodium vivax - Malaria MC form of malaria - ANSWERPlasmodium vivax What allele protects against malaria - ANSWERSickle cell allele Plasmodium vivax is injected as a _________ and spreads through the body as ________ - ANSWERInjected as a sporozoite Spreads through body as merozoites (pathogenic stage) Protozoa spread by anopheles mosquito and causes most fatal form of malaria. Black water fever (urinating oxidized blood) - ANSWERPlasmodium falciparum Protozoa in cat feces and uncooked meat that causes miscarriages - ANSWERToxoplasma gondii - Toxoplasmosis Protozoa spread by kissing reduviid bug that causes Chaga's disease - ANSWERTrypanosoma cruzi - Trypanosomiasis Protozoa spread by Tsetse fly that causes African sleeping sickness - ANSWERTrypanosoma gambiense- Trypanosomiasis Fungal virulence factor that attacks skin - ANSWERKeratinase Fungal virulence factor that attacks muscle - ANSWERProteinase Fungal virulence factor that attacks CT - ANSWERElastase Fungal infection in nuts and grains that causes a fungus ball to grow in lungs. Aflatoxin causes primary liver cancer - ANSWERAspergillus fumigatus - Aspergillosis Endemic fungus on Eastern seaboard - ANSWERBlastomycosis

Endemic fungus in SW deserts. San Joaquin valley fever - ANSWERCoccidiomycosis Endemic fungus in MI/OH valleys. Causes calcific lesions in lung similar to TB - ANSWERHistoplasmosis Fungal infection in pigeon droppings. MCC of death in AIDS - ANSWERPneumocystis carinii Fungal infection in rose bush thorns - ANSWERSporotherix schenckii - Sporotrichosis Bacterial shape: "many shapes" - ANSWERPleomorphic What shape is strep - ANSWERLinear A cluster of bacteria - ANSWERStaph Comma shaped bacteria - ANSWERVibrio Bacterial virulence factor for B hemolytic strep that dissolves clots - ANSWERStreptokinase Bacterial virulence factor for staph that catalysts formation of fibrin from fibrinogen - ANSWERCoagulase Bacterial virulence factor for staph that breaks down RBCS - ANSWERHemolysin Bacterial virulence factor exotoxin for staph or strep that kills WBCs - ANSWERLeukocidin Bacterial virulence factor for staph, strep, or clostridia that breaks down tissue "cement" of hyaluronic acid and facilitates dissemination - ANSWERHyaluronidase Bacteria that grow at 15C or lower - ANSWERPsychophilic Bacteria that grow at 25-40C (optimal is 37C - human temp) - ANSWERMesophilic Type of bacteria that are killed by fever - ANSWERMesophilic Bacteria that grow at 45C or above - ANSWERThermophilic MCC of meningitis in newborns (2) - ANSWER1. E. Coli

  1. Listeria MCC of meningitis in children (2) - ANSWER1. Strep pneumoniae
  2. Neisseria meningitides

Which meningitis is the only that presents with a rash - ANSWERNeisseria meningitides MCC of meningitis in adults - ANSWERStrep pneumoniae Most lethal meningitis that causes primary amoebic meningoencephalitis - ANSWERNaegleria fowleri Protozoa in food and water that causes amoebic dysentery (mild diarrhea). Cyst is infective - ANSWEREntamoeba histolytica - Amebiasis Protozoa that is in stream water and causes flatulence, poor absorption, mucousy diarrhea. Cyst is infective - ANSWERGiardia lamblia - Giardiasis (beaver fever) Protozoa spread by sandflies. Viscerotropic - ANSWERLeishmania donovani - Kala- Azar disease/Leishmaniasis Protozoa spread by female anopheles mosquito. Causes anemia and chronic splenomegaly - ANSWERPlasmodium vivax - Malaria MC form of malaria - ANSWERPlasmodium vivax What allele protects against malaria - ANSWERSickle cell allele Plasmodium vivax is injected as a _________ and spreads through the body as ________ - ANSWERInjected as a sporozoite Spreads through body as merozoites (pathogenic stage) Protozoa spread by anopheles mosquito and causes most fatal form of malaria. Black water fever (urinating oxidized blood) - ANSWERPlasmodium falciparum Protozoa in cat feces and uncooked meat that causes miscarriages - ANSWERToxoplasma gondii - Toxoplasmosis Protozoa spread by kissing reduviid bug that causes Chaga's disease - ANSWERTrypanosoma cruzi - Trypanosomiasis Protozoa spread by Tsetse fly that causes African sleeping sickness - ANSWERTrypanosoma gambiense- Trypanosomiasis Fungal virulence factor that attacks skin - ANSWERKeratinase Fungal virulence factor that attacks muscle - ANSWERProteinase Fungal virulence factor that attacks CT - ANSWERElastase

Fungal infection in nuts and grains that causes a fungus ball to grow in lungs. Aflatoxin causes primary liver cancer - ANSWERAspergillus fumigatus - Aspergillosis Endemic fungus on Eastern seaboard - ANSWERBlastomycosis Endemic fungus in SW deserts. San Joaquin valley fever - ANSWERCoccidiomycosis Endemic fungus in MI/OH valleys. Causes calcific lesions in lung similar to TB - ANSWERHistoplasmosis Fungal infection in pigeon droppings. MCC of death in AIDS - ANSWERPneumocystis carinii Fungal infection in rose bush thorns - ANSWERSporotherix schenckii - Sporotrichosis Common name for cutaneous mycoses - ANSWERRingworm/dermatophytoses Superficial fungal infection of skin - ANSWERCutaneous mycoses/ringworm/dermatophytoses How are cutaneous mycoses/ringworm diagnosed? (2) - ANSWER1. Woods lamp (UV light)

  1. Skin scrapings tested in KOH Ringworm of beard - ANSWERTinea barbae Ringworm of scalp - ANSWERTinea capitis Ringworm of body - ANSWERTinea corporis Ringworm of groin - Jock itch - ANSWERTinea cruris Ringworm of foot - Athlete's foot - ANSWERTinea pedis Ringworm of nail - ANSWERTinea unguinum Rickettsial pox is caused by what pathogen - ANSWERRickettsia akari Which Rickettsia pathogen causes epidemic typhus (Bril-Zinsser's disease) - ANSWERRickettsia prowazeki Which Rickettsia pathogen causes trench fever - ANSWERRickettsia quintana Which Rickettsia pathogen causes Rocky Mountain spotted fever with a dermacenter andersoni rash - ANSWERRickettsia rickettsii

Which Rickettsia pathogen causes scrub typhus - ANSWERRickettsia tsutsugamushi Which Rickettsia pathogen causes murine typhus (endemic) - ANSWERRickettsia typhi/mooseri Which Rickettsia pathogen causes Q fever - ANSWERCoxiella burnetii Which Rickettsia pathogen is the only one that is Weil-Felix (-) - ANSWERCoxiella burnetii Which 2 Rickettsia pathogens are spread via mites? - ANSWERRickettsia akari Rickettsia tsutsugamushi Which 2 Rickettsia pathogens are spread via lice? - ANSWERRickettsia prowazeki Rickettsia quintana Which Rickettsia pathogen is spread via wood ticks? - ANSWERRickettsia rickettsii Which Rickettsia pathogen is spread via fleas? - ANSWERRickettsia typhi/mooseri Which Rickettsia pathogen is in milk? - ANSWERCoxiella burnetii Eukaryotes - ANSWER________________ = true nucleus, organelles. E.g human cells, Protozoa like Giardia and amoeba Prokaryotes - ANSWER______________ = no true nucleus, no organelles (e.g. No mitochondria) E.g. Bacteria Family and genus - ANSWERHow are organisms classified/organized? genus and species - ANSWERHow are oraganisms named? Kingdom Phylum Class Order Family Genus Species - a way to organize organisms - ANSWERThe pneumonic "King Paul Can Only Find Good Spices" stands for what and means what? Gram positive - ANSWERGram positive or gram negative Shape of cell = cocci Family = micrococcaccae Genus = micrococcus, staphylococcus

Gram positive - ANSWERGram positive or gram negative Shape of cell = cocci Family = streptococcaccae Genus = streptococcus, enterococcus Gram positive - ANSWERGram positive or gram negative Shape of cell = bacilli Family = bacillaccae (spore formers) Genus = bacillus, clostridium-ANAEROBIC Gram positive - ANSWERGram positive or gram negative Shape of cell = bacilli Family = lactobacillacae Genus = lactobacillus Gram negative - ANSWERGram positive or gram negative Shape of cell = cocci Family = neisseriaccae Genus = neisseria Gram negative - ANSWERGram positive or Gram negative Shape of cell = bacilli Family = enterobacterioccae, vibrianaccae, spirillaccae, pseudomonadacceae, pasteurellaceae, bacteroidosceae Genus = eneterbacter, escherichia, klebsiella, proteus, salmonella, serratia, shigella, yersina, vibrio, campylobocter, pseudomonas, bacteroides=anaerobic Adenoviridae - ANSWERWhat is the virus family of the DNA human virus Adenovirus Papillomaviridae - ANSWERWhat is the virus family of the DNA human virus papillomavirus Herpesviridae - ANSWERWhat is the virus family of the DNA human virus' herpes simplex virus, varicella-zoster virus, cytomegalovirus, and Epstein Barr Virus? Poxviridae - ANSWERWhat is the virus family of the DNA human virus' smallpox, vaccinia virus, molluscum contagiosum virus? Hepadnaviridae - ANSWERWhat is the virus family for the DNA human virus hepatitis B? Paramyxoviridae - ANSWERWhat is the virus family for the RNA human viruses measles, mumps, respiratory syncytial virus?

Orthomyxoviridae - ANSWERWhat is the virus family for the RNA human viruses influenza virus A, B, and C? Rhabdoviridae - ANSWERWhat is the virus family of the RNA human virus rabies? Filoviridae - ANSWERWhat is the virus family of the RNA human viruses ebola and marburg virus? Picornaviridae - ANSWERWhat is the virus family of the RNA human viruses Rhinovirus, Poliovirus, ECHO virus, and coxsackie? Togaviridae - ANSWERWhat is the virus family of the RNA human viruses Rubella, Western and Eastern Equine encephalitis? Flaviviridae - ANSWERWhat is the virus family for the RNA human viruses Dengue virus, yellow fever, and St Louis Encephalitis? Caliciviridae - ANSWERWhat is the virus family of the RNA human virus Norwalk virus (causes gastroenteritis)? IgA - ANSWERWhich antibody is a secretory antibody, in mucous membranes (saliva, tears), and seen in breast milk? IgD - ANSWERWhich antibody helps IgG? IgE - ANSWERWhich antibody are seen in parasitic(worms) infections, allergic reactions, and increases in Hodgkin's disease (Reed-Sternberg cells)? IgG - ANSWERWhich antibody is first to increase in SECOND exposure, most numerous, only one that crosses the placenta, and has an anamnestic response? IgM - ANSWERWhich antibody is a pentameter (10 binding sites), is the largest and heaviest, and first to increase in FIRST exposure? I - ANSWERInterleukin ________ = lymphocyte activating factor, made by macrophages, and for brain and nervous tissue II - ANSWERInterleukin _______ = T-cell growth factor, made by CD4 cells, (CD4 = T- helper cell "quarterback of immune system" and directs response of immune system) III - ANSWERInterleukin ________ = made by big bone marrow and in blood and lymphatic system major histocompatibility complex (MHC) - ANSWER_______________________ act as a post on surface (self vs non-self), involved with tissue graft reflection and organ rejection.