Download Anatomy of the Skin and Bones: Structure, Function, and Healing Processes - Prof. Mary E. and more Study notes Physiology in PDF only on Docsity! Dermis Multiple layers of connective tissue of different kinds Most superficial region is aereolar (loose) connective region called papillary region Papilla- means finger like projections/shapes. Contains sensory nerve endings to convey sense of touch. Meissner corpuscle gives sense of gentle touch Dermis Dense irregular CT of reticular region Has elastic fibers. Dermis “cast of char Contains… Modifications of epith called “glands” Glands – invaginates (meaning making a pocket thrudermis) Sweat glands called Sudeeiferous glands: thermo regulartion. Eccrine sweat glands: secrete watery/salty solution Apocrine sweat gland: different in product they make and where found. Found in groind and armpit area. Produce thicker, muskier sweat. The kind of secretion that bacteria love. Sebaceous glands (oil glands): associated with hair follicles. Sebaceous glands dump into hair follicles. Oil shoots thru hair. Arrector pili muscle: thin, tiny Muscle anchoring hair follicle making hair standing up. Lamellated sensory nerve ending, layered like an onion for sensory. Pressure receptor. Pepilla of the hair is the only place where hairactually grows Nails are comprssed layers of keratin on fingers and toes. Nail matrix, cells that add more keratin and add more nail,, How wounds heal… Varies depends on how wound is. Abrasion: Most superficial wound only involves epidermis. When a gap is introduced into epithelium, epith are gonna divide. Mitosis is triggered to fill in the gap. The action of ripping the cells apart triggers mitosis until they are touching each other again. Contact inhibition stops mitosis by once they are all touching each other again. Anything more serious than a cut into the epidermis is “deep wound healing. Bleed bc of cutting into CT. Collagen fibers and fibro blasts and nerve endings and blood vessels. Inflammatory phase: defense mechanism to stop pathogens from the outside. Calls white blood cells. Wounded blood factors send out chemical signals to attract white blood cells to come to that area. They eat of debris to each debris. Blood quagulates ad clots at the surface on contact with air. Migration phase: refers to migrations of epith cells and fibroblast in to fill in the wound. Presumable while this goes on, the blood vessels are healing and stop leaking. -clot becomes scab -epith cells migrate -Fibroblasts begin to form scar tissue (fibrosis) -granulation means evidence of wound healing. Tissue is health enough to start healing Proliferation phase: more cell division of those migrated cells to fill in the gaps. Maturation phase: finshing healing epith. Scab is going to form. Fibroblsst lay down collagen that’s thicker than original, less vascularized than tissue, lest elastic fibers. Rased scar means theres more collagen from a deep wound. New scar tissue is white because it is less vascularized. Keloid scar develops forming beyond the profile of the original cut. Forms irregular scars. Fibrosis means scar tissue forming. Bed sores: Wound of pressure formed by pressure from staying under pressure from not moving around.