Download NAPRX, CNPR Exam 2022 (160 Questions & Answers). and more Exams Nursing in PDF only on Docsity! NAPRX/CNPR EXAM 2022 (160 QUESTIONS & ANSWERS) 1.How are drugs sorted into therapeutic groups and classes? A. first by the conditions that they are used to treat, and then by their mechanisms of action B. first by their mechanisms of action, and then by their therapeutic effects C. first by their side effects, and then by therapeutic effects D. first by their toxically, and then by their effectiveness 2.Bone marrow transplants… A. … require that the patient first undergo chemotherapy or radiation to kill the diseased stem cells and promote white blood cell production. B. … are a type of stem cell therapy, unless patient’s own cells are reinjected. C. … are always a type of stem cell therapy. D. … can help people with leukemia, a condition in which the body does not produce enough white blood cells. 3.What does AMA stand for? C. American Medical Association 4.What section of a drug’s package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits? B. contraindications 5.What is tertiary care? B. highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems 6.Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual? C. brand quality 7.What are vasodilators used to do? A. decrease vascular resistance and increase blood flow B. mimic pathogens to stimulate the immune system C. narrow the blood vessels D. stimulate the CNS to make the heart beat faster D. Pharmacodynamics studies the time required for a drug’s absorption. 21.What proportion of the drugs tested on human subjects are eventually approved by FDA? A. about 20% B. about 60% C. about 70% D. about 95% 22. According to a study discussed in your manual, how do most physicians prefer to receive their drug samples? A. by borrowing them from hospitals B. by ordering them over the Internet C. by trading them for services D. directly from sales representatives 23.Which of the following is an example of a central value? A. I buy Advil to show that I’m modern consumer. B. I like Advil because we were both born in the 80s. C. I prefer Advil because I like the flavor. D. I prefer Advil because it’s easier to swallow. 24.Which of the following specialties likely has the MOST emergency calls? A. cardiology B. psychiatry C. urology D. All specialists have the same number of emergency calls. 25.What affects the rate of active transport? A. the availability of carriers, but not energy B. the availability of energy, but not carriers C. the availability of carriers and energy D. neither the availability of carriers, nor the availability energy 26.Over the last few decades, what has happened to the FDA approval time for new drugs? A. It has been lengthened to ensure safer drug products. B. It has been lengthened to limit DTC marketing. C. It has been shortened to improve drug quality. D. It has been shortened to reduce the cost of new drug development. 27.Which of the following would NOT help improve compliance? A. patients liking their providers B. patients using only one pharmacist C. pharmacists understanding how generics differ from brand names drugs D. support groups 28.Which entity chooses a drug’s trade name? A. the drug’s inventor B. the drug’s manufacturer C. the FDA D. the United States Pharmaceutical Council 29.What type of stem cells are obtained from embryos and can develop into any cell type? A. multipotent B. pluripotent C. totipotent D. All stem cells can develop into any cell type. 30.As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it? A. It decreases. B. It increases. C. It remains unaffected because the prescription is needed. D. It remains unaffected because the prescription’s increased cost is offset by its perceived value. 31.Most involuntary movements come from which type of muscle tissue? A. cardiac and smooth B. only skeletal C. skeletal and cardiac D. skeletal and smooth 32.Which of the following is NOT one of the body’s major organ systems? A. the cardiovascular system B. the cellular system C. the gastrointestinal system D. the musculoskeletal system 33. How do most drugs exert their primary physiological effects? A. by activating synapses between different types of tissues B. by binding to cell receptors that are sensitive to their presence C. by inhibiting synapses between different types of tissues D. through genetic mutation 34. What is the most reliable source of information for determining therapeutically equivalent drug product? A. AMA guide B. Blue Book C. FDA drug list D. Orange Book 35. What does subcutaneous mean? C. beneath the outer skin 36.What should a sales representative do if all of the prime spaces in a drug cabinet are coccupied? A. ask staff for permission to move some of the other products in the cabinet B. ask staff for permission to throw away expired products in the cabinet C. ask the doctor if he still needs some of the other products in the cabinet D. surreptitiously move your largest competitor’s products out of the way 37.It is inappropriate for physicians’ prescribing behavior to be educated by their personal tastes and idiosyncrasies A. True B. False 38.The FDA defines API as the active ingredient in a drug, which produces the desired change in the body. A. pharmaceutical B. five C. ten D. fifteen 51.What agency regulates the distribution and use of narcotics? A. DEA B. FTC C. OIG D. TSA 52.What is passive diffusion? A. a type of pinocytosis B. membrane transport via vesicles C. the use of energy to help a substance pass from a low concentration gradient to a high one D. when a substance freely moves thorough a membrane from a high concentration gradient to a low one 53.What are the MAIN categories of drugs under FDA jurisdiction? A. active drugs and active placebos B. biopharmaceuticals and nutraceuticals C. non-prescription and nutraceuticals D. prescription and non-prescription 54.Which of the following is a natural uterotonic agent? A. hemoglobin B. leukotriene C. oxytocin D. Vitamin K 55.What are all metabolites? A. active substances B. inactive substances C. injections D. products of metabolism 56.When a drug is administered orally, where does first-pass metabolism occur? A. intestine B. liver C. pancreas D. stomach 57.What is the medical term for swelling? B. edema 58.Which of the following is NOT part of the Seven Step Cascade of Emotion? A. be a consultant, not a rep B. identify what your product does C. reflect D. visualize the power of 10 59.Which part of a clinical research paper is frequently referred to as the road map? A. abstract B. findings C. letter to the editor D. methods 60. Which of the following is a main active ingredient in lung surfactants? A. animal lung extract B. germicides C. sympathomimetic drugs D. theophylline 61.What does parenteral mean? B. injections 62.Which term denotes a type of substance that enhances the action of a drug or antigen? A. adjuvant B. indicated C. ligase D. peptide 63.If a sales representative’s product is placed on the second tier of standard three-tier formulary, which of the following is most likely true? A. it has not been reviewed by the P&T committee. B. it is in a neutral position unless it is at parity with other drugs. C. it probably has exclusive preferred status if it not at parity with any other drugs. D. it will essentially sell itself if it is granted exclusive preferred status. 64.Which of the following is NOT one of the four basic transport mechanisms? A. active transport B. homeostasis C. passive diffusion D. pinocytosis 65.Which statement accurately describes a relationship between drug agonists and antagonists? A. Agonists and antagonists can be used together. B. Agonists and antagonists should not be used together. C. Antagonist drugs activate receptors, while agonists block access to receptors. D. Antagonists are endogenous whereas agonists are man-made. 66.What is the study of the effects and movement of drugs in the human body? C. clinical pharmacology 67.According to your manual, what is a common complaint that physicians have about traditional sampling methods? A. that drug sample supply is too unpredictable B. that patients are less likely to take free samples because they think they are lower quality C. that patients do not like seeing drug representatives in their offices D. that they receive too many drug samples 68.Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power? A. GPO B. In-state wholesaler C. PPO D. RPO A. auscultation B. cardioversion C. catheterization D. echocardiography 81.What do enteric coatings do? A. facilitate vomiting B. help drugs dissolve in stomach C. help drugs enter the bloodstream more quickly D. prevent dissolution in the stomach 82.What is the duration of exclusivity for orphan drugs? A. 6 months B. 1 year C. 7 years D. 15 years 83.What do National Account Managers do? A. act as the sales reps’ primary point of contact with the rest of the corporation B. manage the FDA approval process C. negotiate contracts with MCOs and PBMs D. sell only to pharmacies 84.What does it usually mean if a drug recall is voluntary? A. Pharmacies may choose whether to return the drug or dispense it. B. The FDA has determined that the drug is perfectly safe, but ineffective. C. The manufacturer has recalled the product on its own, but negotiated with the FDA beforehand. D. The manufacturer has recall the product without negotiating with the FDA. 85.Which phase of clinical trials is also known as the pivotal phase? A. Phase I B. Phase III C. Phase IV D. Phase IX 86.During which phase of clinical trials is the new drug’s safety and effectiveness first tested in the target group? A. preclinical B. Phase I C. Phase II D. Phase III 87.How do antacids work? A. by increasing blood flow to the stomach B. by lowering gastric pH C. by raising gastric pH D. by suppressing cholesterol formation by the liver 88. What is one of the biggest time wasters for a pharmaceutical sales rep? A. caterers B. pharmacists C. receptionists D. travel time 89. What happens when equilibrium is reached? A. equal numbers of molecules cross the membrane in both directions B. molecules stop moving C. the concentration gradient decreases indefinitely D. the concentration gradient increases indefinitely 90.What are the most common vectors used in gene therapy? A. autologous antigens B. liposomes C. naked DNA D. viruses 91. What is the percentage fee that the dispenser pays the wholesaler for distribution? A. margin fee B. recharge C. standard fee D. upcharge 92. What is the difference between a chronic (or continuing) reaction, and a delayed reaction? A. Chronic reactions are exaggerated, whereas delayed reactions are idiosyncratic. B. Chronic reactions occur only during treatment, whereas delayed reactions only occur during withdrawal. C. Chronic reactions persist for a long time, whereas delayed reactions take some time to develop. D. Delayed reactions are always idiosyncratic, but chronic reaction not. 93.What is clinical effect? A. federally funded research condition B. the effect of maximum dosage C. the response produced by a medication D. the use of treatment drugs in chemotherapy 94.Which of the following is an example of noncompliance? A. a patient forgetting to take a drug at a specified time a day B. a patient taking a drug, but only because it has been court-mandated C. a pharmacist dispensing a generic equivalent of a drug instead of the brand name D. a physician refusing to prescribe a drug because (s)he does not trust the clinical studies on it 95.What is the average circulation time of blood? A. about a minute B. about 5 minutes C. about 5 to 10 minutes depending on the patient’s age and health conditions D. about 10 minutes 96.What is one way in which pharmaceutical selling is different from selling in most other industries? A. in pharmaceutical sales, the decisions-makers, consumers, and payers are usually the same entity B. Pharmaceutical selling takes less time because doctors are so busy. C. Representatives do NOT sell the end user of the product. D. Representatives DO sell to the end user of the product. A. a weaker patients’ rights movement B. lack of insurance coverage C. less reliance on the Internet D. proliferation of herbal remedies 109. What is the degree to which a medication produces a therapeutic effect? A. diffusion B. efficacy C. protease D. vector 110.What is the most important benefit of electronic prescribing? A. choice B. cost C. inquiries D. safety 111. When does the FDA regulate generic drugs? A. only if they are branded generics B. only if they have been contested C. always D. never 112.Which phase of trials largely determines the clinical dose? A. preclinical trials B. Phase II trials C. Phase III trials D. Phase IV trials 113.What is an advantage of inactivated vaccines over attenuated vaccines? A. Inactivated vaccines are less expensive to prepare. B. Inactivated vaccines have a higher probability of eliciting the desired immunological response. C. Inactivated vaccines have a more stable shelf life. D. Inactivated vaccines only require a single dose. 114.Which medical term denotes a low supply of oxygen due to blood flow? A. potentiation B. ischemia C. TID D. titration 115.What are the two main of prescription drug marketing? A. (1) marketing to insurance companies, and (2) marketing to pharmacies B. (1) PBM marketing, and (2) marketing to governments C. (1) professional physician promotions, and (2) direct-to-consumer advertising D. (1) publicly-funded marketing, and (2) physician-funded marketing 116.What is the site of delivery for subcutaneous injections? A. fatty tissue beneath the surface of the skin B. lymphatic tissue C. muscle tissue D. the stomach, via a special type of needle 117.What must be contained in the Description section of a pharmaceutical package insert? A. adverse effects B. mechanism of action C. pharmacokinetics D. the proprietary name and established name 118.What is the study of a mediation’s effects as it through the body? A. pharmacodynamics B. pharmacogenetics C. pharmacogenomics D. pharmacokinetics 119.Customers purchase products from people they like, trust, and respect. This is called the . A. closing of the sale B. first time advantage C. likeability factor D. power of knowledge 120.What is penicillin’s mechanism of action? A. It disturbs bacterial cell wall synthesis. B. It inhibits the production of viruses. C. It prevents proper DNA replication. D. It sends a messenger to the bone marrow to produce extra white blood cells. 121.According to your manual, how has the U.S. healthcare marketplace changed in the last few decades? A. Fewer and fewer prescription drugs have been made available as OTCs. B. Managed care has been increasingly replaced by more patient-centered approaches. C. The aging Baby Boomer generation has begun demanding more personalized attention. D. There has been decreased emphasis on preventive health. 122.How does pharmaceutical marketing help narrow the treatment gap? A. It encourages patients to take more active roles in their healthcare. B. It makes doctors more skeptical of the pharmaceutical industry. C. It makes patients more skeptical of their doctors’ opinions. D. all of those 123.What do immunosuppressive agents do? A. decrease risk of infection B. increase risk of infection C. increase the risk of rejection of foreign bodies D. treated psoriasis 124.What types of drugs are EGFR inhibitors? A. antineoplastics B. cardiovascular agents C. CNS agents D. mitotic inhibitors 125.Which of the following means outside of the living body? A. en vivo B. to assess the drug’s effectiveness C. to assess the professionalism of the study staff D. to assess the subjects’ demographics 138.A generic version is likely to have some inactive ingredients that are different from those of the original drug. A. True B. False 139.Which of the following is an example of a functional value? A. I drink Coca-Cola because I am a citizen of the world. B. I drink Coca-Cola because I like looking like a traditionalist. C. I drink Coca-Cola because I like the taste. D. I drink Coca-Cola because it is an international brand. 140.Where are most drugs metabolized? A. interstitial spaces B. liver C. stomach D. the bloodstream 141.What is essential to the ethical requirement that subjects be selected fairly? A. Selection criteria should be well-supported by documented evidence. B. Studies should make every attempt to conduct research on subjects who are underprivileged and in need of medical attention. C. Subjects should be selected based on scientific objectives. D. all of these 142.Which of the following is the most appropriate salutation for a cover letter if you cannot find a contact name? A. Dear Personnel Department B. Dear Sir or Madam, C. Dear Sir, D. To Whom It May Concern, 143.What is part of becoming an indispensable pharmaceutical sales rep? A. asking for feedback B. giving the doctors anything they ask for to prescribe your products C. keeping your market share goals the same each term D. not bothering busy doctors in hospitals 144.Which of the following is NOT typically included in the indications and usage section of the package insert information? A. diseases or conditions that the drugs is approved to treat B. the drug’s active metabolites C. the drug’s recommended usual dosage D. the drug’s usual dosage range 145. Which term denotes the practice of classifying physicians and other potential prescribers by anticipated prescription volume? A. conditioning B. deciling C. detailing D. private labeling 146.What makes a drug eligible for fast track approval from the FDA? A. It is a generic that has already been approved as a branded drug. B. It is a new drug. C. It is less expensive than what is currently on the market. D. It treats patients with a serious, life-threatening condition. 147.In the gastrointestinal tract, help break up tablets to ensure full release of the active pharmaceutical ingredient. A. binders B. disintegrants C. dispersing agents D. lubricants 148. According to your manual, what does the PDRP do? A. It educates patients on their treatment options. B. It expands sales representatives’ access to patient information. C. It improves communication between sales representatives and patients in doctors’ offices. D. It limits sales representatives’ abilities to see individual physicians’ prescribing data. 149.What are the components of the centrals nervous system? A. the brain and sense organs B. the brain and spinal cord C. the brain, spinal cord, and peripheral nervous system D. the spinal cord and sense organs 150.Which term denotes the origin or cause of a medical condition? A. cytology B. discovery C. etiology D. pathology 151.Patients diagnosed with Type 1 diabetes … B. … have an autoimmune disease. 152.Which DTC pharmaceutical marketing tactic is permitted in European countries? A. disease state ads 153.What is one way in which psychologists DIFFER from psychiatrists? B. Psychologists deal more with emotional than physical issues. 154. What are PBMs? C. organizations that negotiate between pharmaceutical companies and large drug purchasers. 155.How does the Hatch-Waxman Act protect research-based drug manufacturers? C. by providing a 30-month cooling off period 156.What is the process of adjusting drug doses to achieve the maximum positive therapeutic effects while minimizing adverse or side effects? D. titration 157.Which of the following is studied more in pharmacodynamics than in pharmacokinetics? C. the transportation of the drug to the specific site for drug-receptor interaction 158.How does the healthy human immune system use MHC markers? D. Substances without MHC markers are discerned as foreign and targeted for destruction.