Download NAPRx/CNPR Exam180Questions & Answers most recent update 2023/2024. and more Exams Nursing in PDF only on Docsity! NAPRx/CNPR Exam180Questions & Answers most recent update 2023/2024. 1. How are drugs sorted into therapeutic groups and classes? ANSWER first by the conditions that they are used to treat. and then by their mechanisms of action 2. Bone marrow transplants. ANSWER are a type of stem cell therapy. unless the patient's own cells are reinjected. 3. What does AMA stand for? ANSWER American Medical Association 4. What section of a drug's package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits? ANSWER contraindications 5 What is tertiary care? ANSWER highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems 6. Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual? ANSWER brand quality 7 What are vasodilators used to do? ANSWER decrease vascular resistance and increase blood flow 8. What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant? ANSWER Steady State 9. Which statement is TRUE about ocular administration? ANSWER Ocular administration is used primarily to treat the eye. 10.Which entities invest's the most money in pharmaceutical R&D? ANSWER U.S. pharmaceutical companies 11.How are most drugs excreted? ANSWER via the kidneys 12.Over the last few decades, what has happened to legal limitations on sales' reps ANSWER discussions about label uses? 27.Which of the following would NOT help improve compliance? pharmacists understanding how generics differ from brand name drugs 28.Which entity chooses a drug's trade name? the FDA 29.What type of stem cells are obtained from embryos and can develop into any cell type? totipotent 30.As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it? It remains unaffected because the prescription is needed 31.Most involuntary movements come from which type of muscle tissue? cardiac and smooth 32.Which of the following is NOT one of the body's major organ systems? the cellular system 33.How do most drugs exert their primary physiological effects? by binding to cell receptors that are sensitive to their presence Upgrade to remove ads Only $2.99/month 34.What is the most reliable source of information for determining therapeutically equivalent drug products? Orange Book 35.What does subcutaneous mean? beneath the outer skin 36.What should a sales representative do if all of the prime spaces in a drug cabinet are occupied? ask staff for permission to move some of the other products in the cabinet 37.It is inappropriate for physicians' prescribing behaviors to be educated by their personal tastes and idiosyncrasies TRUE 38. The FDA defines API as the active ingredient in a drug, which produces the desired change in the body. pharmaceutical 39.What are the 2 legal classifications of wholesalers? primary and secondary wholesale distributors 40. What term describes the usage of a medication for purposes other than the FDA-approved indications on the labeling? of-label usage 41.What is the acronym for pharmacokinetics? PK 42.The dosage range of a drug that is both safe and beneficial is known as the therapeutic window. True 43.What is typically NOT a characteristic of a pharmaceutical sales rep? Pharmaceutical sales reps are not concerned about competitors. 44.What entity grants drug patents? The US Patent and Trademark Office 45.Which of the following refers to all active and inert pharmaceutical ingredients in a drug,including fillers and colors? formulation 46.What is the difference between potency and efficacy? potency refers to the drug's strength, while efficacy refers to its effectiveness 47.What is the minimum level of education required for a nurse practitioner? a graduate degree 48.How many names must a drug have? at least three 49.How has a longer development time increased the cost of bringing a new drug to market? Increasing the cost of capital 50.Senior citizens consume over times as many pharmaceuticals as people under 65. three 51.What agency regulates the distribution and use of narcotics? DEA 52.What is passive diffusion? when a substance freely moves through a membrane from a high concentration gradient to a low one 53. What are the MAIN categories of drugs under FDA jurisdiction? prescription and non prescription 55.What are all metabolites? products of metabolism 56.When a drug is administered orally, where does first-pass metabolism occur? liver 57.What is the medical term for swelling? edema 58.Which of the following is NOT part of the Seven Step Cascade of Emotion? be a consultant, not a rep 59.Which part of a clinical research paper is frequently referred to as the road map? abstract 60.Which of the following is a main active ingredient in lung surfactants? theophylline 61.What does parenteral mean? injection 62.Which term denotes a type of substance that enhances the action of a drug or antigen? adjuvant 63.If a sales representative's product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true? It probably has exclusive preferred status if it is not at parity with any other drugs 64. Which of the following is NOT one of the four basic transport mechanisms? homeostasis 65.Which statement accurately describes a relationship between drug agonists and antagonists? Agonists and antagonists can be used together. 66.What is the study of the effects and movement of drugs in the human doctors often use drug samples to treat patients who otherwise could not afford it 80. Which medical term denotes the use of a stethoscope to listen to the heart? auscultation 81.What do enteric coatings do? prevents dissolution in the stomach 82.What is the duration of exclusivity for orphan drugs? 7 years 83.What do National Account Managers do? negotiate contracts with MCO and PBM 84.What does it usually mean if a drug recall is voluntary? The manufacturer has recalled the product on its own. but negotiated with the FDA beforehand. 85. Which phase of clinical trials is also known as the pivotal phase? Phase III 86.During which phase of clinical trials is the new drug's safety and effectiveness first tested in the target group? Phase II 87.How do antacids work? by raising gastric PH 88.What is one of the biggest time wasters for a pharmaceutical sales rep? Travel Time 89.What happens when equilibrium is reached? equal numbers of molecules cross the membrane in both directions 90.What are the most common vectors used in gene therapy? viruses 91.What is the percentage fee that the dispenser pays the wholesaler for distribution? upcharge 92.What is the difference between a chronic (or continuing) reaction, and a delayed reaction? chronic reactions persist for a long time, delayed reactions take some time to develop 93 What is clinical effect? the response produced by a medication 94.Which of the following is an example of noncompliance? a patient forgetting to take a drug at a specified time of day 95.What is the average circulation time of blood? about a minute 96.What is one way in which pharmaceutical selling is different from selling in most other industries? representative do NOT sell to the end user of the product 97.From what types of entities do primary wholesale distributors buy most of their drugs? manufacturers 98. What is the Office of the Inspector General (01G)? an arm of the Dept of Health and Human Services 99.What are doctors required to consider when deciding whether or not to prescribe a particular drug? the severity of the disorder being treated and the effect it has on the patients quality of life 100. Which entity assigns a new drug its generic names? the United States Adopted Name Council 101. Drugs can be used days beyond their expiration date. drugs never can be used beyond expiration date 102. What is necessary for a drug to be excreted extensively via the kidneys? The drug must be water-soluble, and not bind too tightly to protein in the bloodstream 103. Which organization or individual initiates the clinical trial and finances the study? sponsor 104. The name describes the atomic or molecular structure of a drug. chemical 105.Under PhRMA Code, is it acceptable or unacceptable for a pharmaceutical sales rep to take a physician and the physician's spouse to a fundraising dinner? 119. Customers purchase products from people they like, trust, and respect. This is called the likeability factor 120. What is penicillin's primary mechanism of action? it disturbs bacterial cell wall synthesis 121. According to your manual, how has the U.S. healthcare marketplace changed in the last few decades? managed care has been increasingly replaced by more patient centered approaches 122. How does pharmaceutical marketing help narrow the treatment gap? it encourages patients to take more active roles in their healthcare 123. What do immunosuppressive agents do? reduce risk of rejection of foreign bodies 124. What types of drugs are EGFR inhibitors? antineoplastics 125. Which of the following means outside of the living body? ex vivo 126. The FDA requirements for nutraceuticals and medicinal herbs are just as stringent as for pharmaceuticals. False 127.What is the estimated net gain of private-sector healthcare's contributions to increased U.S. life expectancy? 2-5 trillion 128. Which statement is TRUE regarding post-approval drug monitoring? the FDA can choose to withdraw their approval if new evidence arises 129. Which term denotes when tolerance to one medication causes increased tolerance to another medication? cross tolerance 130. Patents expire years from the date of filing. twenty 131. After a trade-name drug's patent expires, how may generic versions of it be sold? only under the branded generic name 132. What is required for a new pharmaceutical to be considered a viable therapy? it is more effective, causes fewer serious adverse effects than other drugs on the market 133. Under the AMA guidelines, who is ultimately responsible for minimizing conflicts of interest? doctors 134. The act of dispensing a pharmaceutical alternative for the product prescribed is pharmaceutical substitution 135. What does it mean if a drug is said to have a wide margin of safety? there is a lower chance of severe or life threatening side effects 136. Which of the following is the correct medical acronym for effective dose? ED 137. Why is one group of subjects given an active drug, while another group only receives a placebo? to assess the drugs effectiveness 138. A generic version is likely to have some inactive ingredients that are different from those of the original drug. True 139. Which of the following is an example of a functional value? I drink coca cola because I like the taste 140. Where are most drugs metabolized? liver 141. What is essential to the ethical requirement that subjects be selected fairly? subjects should be selected based on scientific objectives 142. Which of the following is the most appropriate salutation for a cover letter if you cannot find a contact name? Dear Sir or Madam 143. What is part of becoming an indispensable pharmaceutical sales rep? asking for feedback 144. Which of the following is NOT typically included in the indications and usage section of the package insert information?