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NAPSRx CNPR Chapter 21: Pharmaceutical
Terminology Reasearched questions
A.A. ANSWER>>>>- dosage "of each"
A.C. ANSWER>>>>- dosage, "before meals"
AAHP ANSWER>>>>- American Association of Health Plans, includes health
maintenance organizations (HMOs), preferred provider organizations (PPO), other
forms of managed care, and utilization review organizations (UROs)
absorption rate ANSWER>>>> - the rate at which a drug is taken into a persons
bloodstream with in a specified time period. can vary by person.
AC ANSWER>>>>- Anti Cholinergic
;side effect (dry mouth, blurred vision, urinary retention, etc.)
accelerated approval ANSWER>>>>- Created in early 1990's, an expedited approval of
drugs that represent a major advance in addressing serious or life - threatening
diseases for which no effective alternative treatments exist.
- Under accelerated approval, the FDA accepts a surrogate endpoint as evidence of
effectiveness, and requires post-marketing studies to confirm the drug's benefits
A.C.E. inhibitors ANSWER>>>> - Angiotensin Converting Enzyme inhibitors.
- A class of drugs used to treat cardiovascular conditions such as hypertension and
chronic heart failure
action letters ANSWER>>>>- OFFICIAL FDA RESPONSE to NDA. the message may be an
approval letter, approvable letter, or a non - approvable letter
active metabolite ANSWER>>>>- A biological active PRODUCT of a medication's
metabolism
acute illness ANSWER>>>>- a condition or illness that only lasts for a short period of
time. (e.g. common cold)
acute ANSWER>>>>- abrupt is onset and short term
AD LIB ANSWER>>>>- dosage, "freely"
additions ANSWER>>>>- TWO OR MORE medications are used together and the clinical
effect is equal to the sum of their individual effects
adherence ANSWER>>>>- overall PROPER USE of medication (time, schedule,
technique, etc. )
adjuvant ANSWER>>>>- substance that ENHANCES drug/antigen action.
- used with primary therapy
A.D.M.E. ANSWER>>>>- Absorption, Distribution, Metabolism, Excretion
- assay that assess impact on human body
adverse drug reaction ANSWER>>>> - unwanted, negative consequence from the
medication
adverse effect ANSWER>>>> - unwanted effect caused by medication
adverse event ANSWER>>>> - UNANTICIPATED EVENT that involves risk for the patient
and/or others
A.F. ANSWER>>>>- Atrial Fibrillation
- irregular, fast heartbeat causing poor blood flow
affinity ANSWER>>>>- MEASURE OF BINDING of an antibody to an antigen
agonist ANSWER>>>> - drug that binds with receptors that INITIATES drug rxns.
alignment ANSWER>>>>- allocation of client responsibilities
AMA ANSWER>>>> - American Medical Association, Chicago, IL
AMCP ANSWER>>>>- Academy of Managed Care Pharmacy
- organization for PHARMACY DIRECTORS
APhA ANSWER>>>>- American Pharmaceutical Association, 1852
- society of PHARMACISTS, and related personnel
amide ANSWER>>>> organic compound, CO=NH
amyloid ANSWER>>>>- extracellular glycoprotein deposits
analgesic ANSWER>>>>- pain reliever
analogue ANSWER>>>>- similar chem/physical structure
anaphylaxis ANSWER>>>> - "foreign substance" causing extreme sensitivity followed by
reaction
ANDA ANSWER>>>>- Abbreviated New Drug Application
androgen ANSWER>>>>- MALE Reproductive Hormone
angiotensin ANSWER>>>>- a peptide, that in angiotensin II form causes
vasoconstriction leading to an increase in blood pressure
antagonist ANSWER>>>>- substance that interferes/inhibits physiological activity of
another
antibody ANSWER>>>>- protein secreted by B plasma cells due to presence of antigen
antigen ANSWER>>>>- protein based substance or toxin that causes secretion of
antibodies through immune response
APAP ANSWER>>>>- Acetaminophen (Tylenol)
APC ANSWER>>>>- Antigen Presenting Cell (dendritic cells, b cells, macrophages)
API ANSWER>>>>- Active Pharmaceutical Ingredient.
- the active ingredient that causes the therapeutic effects
approvable letter ANSWER>>>> An FDA response to an NDA, listing minor issues to be
resolved before granting marketing approval
AWP ANSWER>>>>- Average Wholesale Price
avidity ANSWER>>>> Strength of binding, especially the binding of an antibody to an
antigen