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The clinical practice guidelines for hypertension management. It defines hypertension, discusses its pathophysiology, and provides recommendations for its management. The guidelines are based on evidence and provide recommendations for different age groups and populations. The document also provides references for further reading.
Typology: Exams
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➢
108M people in the United States
➢
$131 Billion in costs were associated with HTN from 2003 to
➢
54% of the nation’s African Americans are hypertensive
➢
46.1% of the nation’s Caucasians are
hypertensive
➢
47M American between ages 45-65 are hypertensive
➢
Men slight > Women
(Centers
Control
Prevention,
Defined: Persistent high pressure exerted in
the arteries
Primary Hypertension (Unknown cause;
AKA essential / idiopathic) 95%
Secondary Hypertension (Caused
by known Underlying disorder) 5%
Systolic (mmHg) Diastolic
(mmHg)
(McCance, Huether, Brashers & Rote,
Complex mechanism of interactions between the RAAS system, the
SNS, and natriuretic hormones
Dysfunction Insulin
Resistance SNS, RAA, NH
Inflammation
Vasoconstriction, Increased Na & H20 Retention
Increased Blood Volume & Increased Peripheral
Resistance
(McCance, Huether, Brashers, & Rote, 2019)
Sustained HTN
➢
Usually asymptomatic— Silent
killer
➢
Severely elevated,
Somatic Complaints
Headache
Blurry vision
Nosebleeds
Fatigue, Dizzy
Palpitations
Edema
(McCance, Huether, Brashers &
Rote, 2019)
Guideline Publication(s)
Organization : American Medical Association
Original CPG : 2013 – 7
th
Joint National Committee (JNC7) Guidelines
Current CPG : 2014 – 8
th
Joint National Committee (JNC8) Guidelines
RN, ANP, PhD, Joel Handler, MD, Daniel T. Lackland, DrPH, Michael L. LeFevre, MD, MSPH, Thomas D. MacKenzie, MD, MSPH,
Olugbenga Ogedegbe, MD, MPH, MS, Sidney C. Smith Jr, MD, Laura P Svetkey, MD, MHS, Sandra J. Taler, MD, Raymond R. Townsend,
MD, Jackson T. Wright Jr., MD, PhD, Andrew S. Narva, MD, & Eduardo Ortiz, MD, MPH
PCP diagnose, treat, & manage HTN
(James, Ortiz et al., 2014)
Clinical Practice Guideline for Hypertension
Application in
Purpose
p of
r g
i u
m ide
a lin
r e
y to
a
c d
a dre
r s
e s & treat HTN in primary care
setting
Most common condition in primary
care
Prevention of increased risk for additional
cardiovascular comorbidities that contribute
to economic burden
(James, Ortiz et al., 2014)
A: strong recommendation – high certainty that net benefit is
substantial based on evidence
B: moderate recommendation – benefit is mod to substantial or
high certainty that the net benefit is moderate
C: weak recommendation – small net benefit with moderate
certainty based on evidence
D: recommendation against – moderate certainty based on
evidence that there is no benefit or risk > benefits
E: expert opinion (Not substantial evidence but committee
recommends)
(James,
et al.,
blood pressure (SBP) 150 mm Hg or diastolic blood pressure (DBP) 90 mm Hg and treat to a goal SBP
< 150 mmHg & Goal DBP < 90 mmHg. Strong Recommendation – Grade A
DBP <90mmHg. (For ages 30-59 years, Strong Recommendation – Grade A; For ages 18-29 years, Expert Opinion – Grade E)
thiazide-type diuretic, calcium channel blocker (CCB), angiotensin-converting enzyme inhibitor (ACEI), or angiotensin receptor blocker
(ARB). (Moderate Recommendation – Grade B)
type diuretic or CCB. (For general black population: Moderate Recommendation – Grade B; for black patients with diabetes: Weak
Recommendation – Grade C)
ARB to improve kidney outcomes. This applies to all CKD patients with hypertension regardless of
race or diabetes status. (Moderate Recommendation – Grade B) (James, Ortiz et al., 2014)
previous visit
6 mos
Continue to monitor patient’s BP on current
medication regimen unless there is a change
(increase/decrease) in BP—TX appropriately.
Centers for Disease Control and Prevention (CDC). (2019). Hypertension Cascade: Hypertension Prevalence, Treatment and Control
Estimates Among US Adults Aged 18 Years and Older Applying the Criteria from the American College of Cardiology and
American Heart Association’s 2017 Hypertension Guideline--NHANES 2013 – 2016.
Atlanta, GA: US Department of Health and Human Services; 2019. Retrieved from:
https://millionhearts.hhs.gov/data-reports/hypertension-prevalence.html
James, P.A., Ortiz, E, et al. (2014). Evidence-based Guideline for the Management of High Blood Pressure in Adults: (JNC8). Journal
of the American Medical Association, 311 (5), 507-20. Retrieved from: https://jamanetwork.com/ on 04/13/2020.
McCance, K. L., Huether, S. E., Brashers, V. L., & Rote, N. S. (2019). Pathophysiology (8th ed.). Retrieved from
https://online.vitalsource.com/#/books/9780323583473/epubcfi/6/2[;vnd.vst.idref=id_cover]!/4/4[pcover]/2[vst
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