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PATHOPHYSIOLOGY FINAL EXAM Questions and Answers 2024.pdf
Typology: Exams
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A professor has taught the students about the pathogenesis of abdominal pain. Which statement by a student indicates the professor needs to review the material?
Low concentrations of anaerobes, such as Streptococci , Lactobacilli , Staphylococci , Enterobacteria , and Bacteroides , produce abdominal pain. Which cardiac chambers have the thinnest wall and why?
The right and left atria; they are low-pressure chambers that serve as storage units and conduits for blood.
A healthcare provider notes that tapping the patient's facial nerve leads to lip twitching. What electrolyte value is correlated with this finding?
Ca ++: 8. mg/dL
What is the cause of functional dysphagia?
Neural or muscular disorders Which gastric hormone inhibits acid and pepsinogen secretion, as well as decreases the release of gastrin?
Somatosta tin
What is one function of the tumor cell marker?
T o s c r e e n i n d i v i d u a l s a t h i g h r i s k f o r c a n c e r
Why is leakage of lysosomal enzymes during chemical injuries significant?
Enzymatic digestion of the nucleus and nucleolus occurs, halting DNA synthesis.
The student wants information about a patient's renal function. What test does the healthcare professional tell the student to evaluate?
Glomerular filtration rate
A student is preparing to irrigate a patient's wound and gathers supplies, including hydrogen peroxide. What response by the health care professional is best?
Tell the student to get some normal saline instead.
A patient suffered multiple traumatic injuries and received many blood transfusions within a few days of the injuries. For which medical condition should the healthcare professional monitor the patient for?
Hemosidero sis
The data reporting that sickle cell disease affects approximately 1 in 600 American blacks is an example of which concept?
Prevalen ce
A patient has a history of excessive use of magnesium-containing antacids and aluminum-containing antacids. What lab value does
the healthcare professional correlate to this behavior?
Phosphate 1. mg/dL
A student asks why some vaccinations are given orally and some are given by injection. What response by the professor is best?
Each route stimulates a different lymphocyte-containing tissue, resulting in different types of cellular and humoral immunity. A person wants to know if eating only plant-based foods is advisable as a way to cut cholesterol to near-zero levels. What response by the health care professional is best?
No, many hormones are made from cholesterol.
What is the initiating event that leads to the development of atherosclerosis?
Injury to the endothelial cells that line the artery walls
The cardiac electrical impulse normally begins spontaneously in the sinoatrial (SA) node because of what reason?
It depolarizes more rapidly than other automatic cells of the heart.
An amniocentesis indicates a neural tube defect when an increase in which protein is evident?
Alpha fetoprotei n
When comparing the clinical manifestations of both diabetic ketoacidosis (DKA) and
hyperglycemic hyperosmolar nonketotic syndrome (HHNKS), which condition is associated with only DKA?
Kussmaul respirations
A student learns what information about acute pancreatitis?
Pancreatic enzymes autodigest pancreatic cells and tissues.
If a patient develops acidosis, the nurse would expect the oxyhemoglobin dissociation curve to react in which manner?
Shift to the right, causing more oxygen (O 2 ) to be released to the cells
A student asks the professor to differentiate Type 2 diabetes mellitus from Type 1. The professors' response would be that Type 2 is best described as what?
Resistance to insulin by insulin- sensitive tissues
The healthcare professional explains to a student that the amount of volume of blood in the heart is directly related to the of contraction.
Pressur e
What is apoptosis?
In regulating vascular mediators released from mast cells, the role of eosinophils is to release what?
Histaminase, which limits the effects of histamine during acute inflammation
A professor has taught a student about skeletal alterations seen in chronic kidney disease. Which statement by the student indicates the professor needs to give more information?
The parathyroid gland is no longer able to secrete sufficient parathyroid hormone.
The action of platelet-derived growth factor is to stimulate the production of which cells?
Connective tissue cells
A patient is in severe shock and is receiving vasopressin. A student asks the health care professional to explain the rationale for this treatment. What response by the professional is most accurate?
Antidiuretic hormone causes vasoconstriction to help increase blood pressure.
What effect is a result of inhibiting the parasympathetic nervous system with a drug such as atropine?
Salivation decreases.
People diagnosed with neurofibromatosis have varying degrees of the condition because of which genetic principle?
Expressivi ty
Which term is used to identify the movement of gas and air into and out of the lungs?
Ventilatio n
A healthcare professional wants to determine the adequacy of a person's alveolar ventilation. What assessment finding is most important for the professional to consider?
Arterial blood gas shows a PaCO (^2) of 44 mmHg.
Renal failure is the most common cause of which type of hyperparathyroidism?
Seconda ry
What is the cause of familial hypercholesterolemia (FH)?
Reduction in the number of low-density lipoprotein (LDL) receptors on cell surfaces
What is the single most common cause of cellular injury?
Hypoxic injury
A student asks the professor how a faulty negative-feedback mechanism results in a hormonal imbalance. What response by the professor is best?
Excessive hormone production results from a failure to turn off the system.
Oxygenated blood flows through which vessel?
Pulmonary veins
A patient in the hospital has hypernatremia. What condition should the healthcare professional assess for?
Hypersecretion of aldosterone
A healthcare professional is caring for four patients. Which patient should the professional assess for hyperkalemia?
Renal failure
The acute inflammatory response is characterized by fever that is produced by the hypothalamus being affected by what?
Endogenous pyrogens
A student asks the healthcare professional to explain the pathophysiologic process of alcoholic cirrhosis. What statement by the professional would not be consistent with complete knowledge about this process?
Inflammation and damage leading to cirrhosis begin in the bile canaliculi.
A healthcare professional tells a student that a patient has lost atrial kick. What would the student expect to see when examining this patient?
Signs of decreased cardiac output
During cell injury caused by hypoxia, why does an increase in the osmotic pressure within the cell occur?
Sodium chloride enters the cell.
The Bainbridge reflex is thought to be initiated by sensory neurons in which cardiac location?
Atri a
Which primary characteristic is unique for the immune response?
The immune response is specifi to the antigen that initiates it.
A patient has been admitted for a possible small intestinal obstruction. What is the first sign the healthcare professional assesses for that would indicate the presence of this condition?
Vomitin g
Which type of immunity is produced by an individual after either natural exposure to the antigen or after immunization against the antigen?
A c t i v e - a c q u i r e d i m m u n i t y
What is the major determinant of the resistance that blood encounters as it flows through the systemic circulation?
Muscle layer of the arterioles
Free radicals play a major role in the initiation and progression of which diseases?
Cardiovascular diseases such as hypertension and ischemic heart disease
A patient asks the healthcare professional why tissue damage occurs in acute rejection after organ transplantation. What response by the professional is best?
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly attack the endothelial cells of the transplanted tissue. Under anaerobic conditions, what process provides energy for the cell?
Glycolys is
A patient reports dumping syndrome after a partial gastrectomy. What does the healthcare professional teach this patient?
Eat small, frequent high-protein meals.
Which statement made by a student indicates the healthcare professional needs to describe the pericardium again?
The student asks the professor to explain what characteristic is demonstrated by lungs with decreased compliance?
Stiffne ss
A student studying biology asks the professor to describe how the ras gene is involved in cancer proliferation. What explanation by the professor is best?
A mutation in this gene allows continuous cell growth.
How do free radicals cause cell damage?
Giving up an electron, which causes injury to the chemical bonds of the cell membrane
A patient had a myocardial infarction that damaged the SA node, which is no longer functioning as the pacemaker of the heart. What heart rate would the healthcare provider expect the patient to have?
40 to 60 beats/min
A patient is having a spirometry measurement done and asks the healthcare professional to explain this test. What response by the professional is best?
To measure the volume and flow rate during forced expiration
How does progressive nephron injury affect angiotensin II activity?
Angiotensin II activity is elevated.
What are blood pressure variations associated with?
The renin-angiotensin system's effect on vasoconstriction
During acidosis, the body compensates for the increase in serum hydrogen ions by shifting hydrogen ions into the cell in exchange for which electrolyte?
Potassiu m
A person has hypothyroidism. What chemical does the healthcare professional advise the person to include in the diet?
Iro n
What is the blood type of a person who is heterozygous, having A and B alleles as codominant?
A class of students has learned about contributing factors to duodenal ulcers. What statement indicates to the professor that the students need a review?
Duodenal ulcers occur with greater frequency than other types of peptic ulcers.
A healthcare professional is conducting community education on vaccinations. Which
statement about vaccines does the professional include in the presentation?
Most viral vaccines are made by using dead organisms.
Which hormone is required for water to be reabsorbed in the distal tubule and collecting duct?
Antidiuretic hormone
During the cardiac cycle, why do the aortic and pulmonic valves close after the ventricles relax?
Reduced pressure in the ventricles creates a negative pressure, which pulls the valves closed.
A healthcare professional is caring for a patient undergoing chemotherapy. What is the skin-related health risk the professional should assess the patient for and be prepared to treat?
Infectio n
A patient has portal hypertension-induced splenomegaly. Which lab value would the healthcare professional associate with this condition?
Low platelet count
A healthcare professional is caring for four patients. Which patient does the professional assess for pulmonary emboli (PE) as the priority?
D e e p v e n o u s t h r o m b o s i s
A healthcare professional is working with a person who drinks several 6 - packs of beer a week. What testing does the professional encourage the person to get?
Hepatic function
What physical sign does the healthcare professional relate to the result of turbulent blood flow through a vessel?
Murmur heard on auscultation
What is the only surface inside the nephron where cells are covered with microvilli to increase the reabsorptive surface area called?
Proximal convoluted tubules A patient has been diagnosed with a renal stone. Based on knowledge of common stone types, what self-care measure does the healthcare professional plan to teach the patient when stone analysis has returned?
Increase water intake.
A patient asks the healthcare professional to describe the cause of gastroesophageal reflux disease (GERD). What response by the professional is best?
Excessive production of hydrochloric acid