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Pharmacotherapeutics for Advanced Practice Nurse Prescribers: Questions & Answers Fully, Exams of Nursing

Watts School of NursingNursing

A comprehensive q&a guide on various pharmacotherapeutic topics, including the use of combined alpha-beta antagonists, nicotine effects, tamsulosin, home medication for seizure patients, black box warning for carbamazepine, photosensitivity from levetiracetam, angiotensin ii receptor blockers (arb), measles immunization, hepatitis b vaccine contraindications, gingival hyperplasia, complement deficiencies, loperamide, ondansetron (zofran), liver function, hypoglycemia, tacrolimus (protopic) for atopic dermatitis, multi-drug therapy for tuberculosis, anemia treatment, angina treatment, education of copd patients using inhaled corticosteroids, and a treatment plan for chronic pain.

Typology: Exams

2023/2024

Available from 05/25/2024

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DO NOT COPY
PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE
PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100%
CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS
LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+
Chapter 1.
An Introduction to Pharmacogenetics
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Genetic polymorphisms account for differences in metabolism, including:
1. Poor metabolizers, who lack a working enzyme
2. Intermediate metabolizers, who have one working, wild-type allele and one mutant
3. Extensive metabolizers, with two normally functioning alleles
4. All of the above
2. Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
1. A need to monitor drugs metabolized by 2D6 for toxicity
2. Increased dosages needed of drugs metabolized by 2D6, such as the
selective seroto reuptake inhibitors
3. Decreased conversion of codeine to morphine by CYP 2D6
4. The need for lowered dosages of drugs, such as beta blockers
3. Rifampin is a nonspecific CYP450 inducer that may:
1. Lead to toxic levels of rifampin and must be monitored closely
2. Cause toxic levels of drugs, such as oral contraceptives, when coadministered
3. Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic
4. Cause nonspecific changes in drug metabolism
PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE
PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100%
CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS
LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+
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Download Pharmacotherapeutics for Advanced Practice Nurse Prescribers: Questions & Answers Fully and more Exams Nursing in PDF only on Docsity!

DO NO TCOP Y PHARMACOTHERAPEUTICS (^) FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ Chapter 1. An Introduction to Pharmacogenetics Multiple Choice Identify the choice that best completes the statement or answers the question.

  1. Genetic polymorphisms account for differences in metabolism, including:
    1. (^) Poor metabolizers, who lack a working enzyme
    2. (^) Intermediate metabolizers, who have one working, wild-type allele and one mutant
    3. (^) Extensive metabolizers, with two normally functioning alleles
    4. (^) All of the above
  2. Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
    1. (^) A need to monitor drugs metabolized by 2D6 for toxicity
    2. (^) Increased dosages needed of drugs metabolized by 2D6, such as the selective seroto reuptake inhibitors
    3. (^) Decreased conversion of codeine to morphine by CYP 2D
    4. (^) The need for lowered dosages of drugs, such as beta blockers
  3. Rifampin is a nonspecific CYP450 inducer that may:
    1. (^) Lead to toxic levels of rifampin and must be monitored closely
    2. (^) Cause toxic levels of drugs, such as oral contraceptives, when coadministered
    3. (^) Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic
    4. (^) Cause nonspecific changes in drug metabolism PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

DO NO TCOP Y PHARMACOTHERAPEUTICS (^) FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. Inhibition of P-glycoprotein by a drug such as quinidine may lead to:
    1. (^) Decreased therapeutic levels of quinidine
    2. (^) Increased therapeutic levels of quinidine
    3. (^) Decreased levels of a coadministered drug, such as digoxin, that requires P-glycopr absorption and elimination
    4. (^) Increased levels of a coadministered drug, such as digoxin, that requires P-glycopro absorption and elimination
  2. Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
    1. (^) Toxic levels of warfarin building up
    2. (^) Decreased response to warfarin
    3. (^) Increased risk for significant drug interactions with warfarin
    4. (^) Less risk of drug interactions with warfarin
  3. Genetic testing for VCORC1 mutation to assess potential warfarin resistance is required prior to prescribing warfarin. 1. (^) True 2. (^) False
  4. Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to prescribing: 1. (^) Erythromycin 2. (^) Digoxin 3. (^) Cetuximab PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

DO NO TCOP Y PHARMACOTHERAPEUTICS (^) FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. Ultra-rapid metabolizers of drugs may have:
    1. (^) To have dosages of drugs adjusted downward to prevent drug accumulation
    2. (^) Active drug rapidly metabolized into inactive metabolites, leading to potential thera failure
    3. (^) Increased elimination of active, nonmetabolized drug
    4. (^) Slowed metabolism of a prodrug into an active drug, leading to an accumulation of
  2. A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to:
    1. (^) Ensure the patient will not have increased adverse drug reactions to the tamoxifen
    2. (^) Identify potential drug-drug interactions that may occur with tamoxifen
    3. (^) Reduce the likelihood of therapeutic failure with tamoxifen treatment
    4. (^) Identify poor metabolizers of tamoxifen PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

DO NO TCOP Y PHARMACOTHERAPEUTICS (^) FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ Chapter 1. An Introduction to Pharmacogenetics Answer Section MULTIPLE CHOICE

  1. ANS: 4 PTS: 1
  2. ANS: 2 PTS: 1
  3. ANS: 3 PTS: 1
  4. ANS: 4 PTS: 1
  5. ANS: 2 PTS: 1
  6. ANS: 2 PTS: 1
  7. ANS: 3 PTS: 1
  8. ANS: 3 PTS: 1
  9. ANS: 2 PTS: 1

ANS:

1 PTS: 1

ANS:

2 PTS: 1

ANS:

3 PTS: 1

PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023/2024 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ Chapter 2. Review of the Basic Principles of Pharmacology Multiple Choice Identify the choice that best completes the statement or answers the question.

  1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to prescribing because:
    1. Distribution of drugs to target tissue may be affected.
    2. The solubility of the drug will not match the site of absorption.
    3. There will be less free drug available to generate an effect.
    4. Drugs bound to albumin are readily excreted by the kidneys.
  2. Drugs that have a significant first-pass effect:
    1. Must be given by the enteral (oral) route only
    2. Bypass the hepatic circulation
    3. Are rapidly metabolized by the liver and may have little if any desired action
    4. Are converted by the liver to more active and fat-soluble forms
  3. The route of excretion of a volatile drug will likely be the:
    Kidneys
    1. (^) Lungs
    2. Bile and feces PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. Skin
  2. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of the drug. Storage reservoirs:
  3. Assure that the drug will reach its intended target tissue
  4. Are the reason for giving loading doses
  5. Increase the length of time a drug is available and active
  6. Are most common in collagen tissues
  7. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
  8. Propensity to go to the target receptor 2. Biological half-life
  9. Pharmacodynamics
  10. Safety and side effects
  11. Azithromycin dosing requires that the first day’s dosage be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose:
  12. Rapidly achieves drug levels in the therapeutic range
  13. Requires four- to five-half-lives to attain
  14. Is influenced by renal function
  15. Is directly related to the drug circulating to the target tissues
  16. The point in time on the drug concentration curve that indicates the first PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. Onset of action
  2. Therapeutic range
  3. Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
  4. When the drug has a wide therapeutic range
  5. When the drug will be administered for a short time only
  6. When there is a high correlation between the dose and saturation of receptor sites 4. To determine if a drug is in the therapeutic range
  7. A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This means that the:
  8. (^) Concentration will produce therapeutic effects 2.^ Concentration will produce an adverse response
  9. Time between doses must be shortened
  10. Duration of action of the drug is too long
  11. Drugs that are receptor agonists may demonstrate what property?
  12. Irreversible binding to the drug receptor site
  13. Upregulation with chronic use
  14. Desensitization or downregulation with continuous use
  15. Inverse relationship between drug concentration and drug action PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. Drugs that are receptor antagonists, such as beta blockers, may cause:
    1. Downregulation of the drug receptor
    2. An exaggerated response if abruptly discontinued
    3. Partial blockade of the effects of agonist drugs
    4. An exaggerated response to competitive drug agonists
  2. Factors that affect gastric drug absorption include:
    1. Liver enzyme activity
    2. Protein-binding properties of the drug molecule 3.^ Lipid solubility of the drug
    3. (^) Ability to chew and swallow
  3. Drugs administered via IV:
    1. Need to be lipid soluble in order to be easily absorbed 2. Begin distribution into the body immediately
    2. Are easily absorbed if they are nonionized
    3. May use pinocytosis to be absorbed
  4. When a medication is added to a regimen for a synergistic effect, the combined effect of the drugs is:
  5. The sum of the effects of each drug individually
  6. Greater than the sum of the effects of each drug individually
  7. Less than the effect of each drug individually PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ drugs given once daily.

  1. Combining an active drug with an inert substance does not affect bioavailability.
  2. Which of the following statements about the major distribution barriers (blood- brain or fetal-placental) is true?
  3. Water soluble and ionized drugs cross these barriers rapidly.
  4. The blood-brain barrier slows the entry of many drugs into and from brain cells.
  5. The fetal-placental barrier protects the fetus from drugs taken by the mother.
  6. Lipid-soluble drugs do not pass these barriers and are safe for pregnant women.
  7. Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both of these types of reactions is to:
  8. Inactivate prodrugs before they can be activated by target tissues
  9. Change the drugs so they can cross plasma membranes
  10. Change drug molecules to a form that an excretory organ can excrete
  11. Make these drugs more ionized and polar to facilitate excretion
  12. Once they have been metabolized by the liver, the metabolites may be:
  13. More active than the parent drug
  14. Less active than the parent drug
  15. Totally “deactivated” so they are excreted without any effect 4.^ All of the above
  16. All drugs continue to act in the body until they are changed or excreted. PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ The ability of the body to excrete drugs via the renal system would be increased by:

  1. Reduced circulation and perfusion of the kidney
  2. Chronic renal disease
  3. Competition for a transport site by another drug
  4. Unbinding a nonvolatile drug from plasma proteins
  5. Steady state is:
  6. The point on the drug concentration curve when absorption exceeds excretion 2. When the amount of drug in the body remains constant
  7. When the amount of drug in the body stays below the minimum toxic concentration
  8. All of the above
  9. Two different pain medications are given together for pain relief. The drug—drug interaction is:
  10. Synergistic
  11. Antagonistic
  12. Potentiat ive 4. Additive
  13. Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT: PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ Which of the following would reduce or inhibit this process?

  1. Protein malnutrition
  2. Iron-deficiency anemia
  3. Both 1 and 2 2
  4. The time required for the amount of drug in the body to decrease by 50% is called:
  5. (^) Steady state 2. Half-life
  6. Phase II metabolism
  7. Reduced bioavailability time
  8. An agonist activates a receptor and stimulates a response. When given frequently over time, the body may:
  9. Upregulate the total number of receptors
  10. Block the receptor with a partial agonist
  11. Alter the drug’s metabolism
  12. Downregulate the numbers of that specific receptor
  13. Drug antagonism is best defined as an effect of a drug that:
  14. (^) Leads to major physiological and psychological dependence 2.^ Is modified by the concurrent administration of another drug PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON
  15. (^) Neither 1 nor

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. Cannot be metabolized before another dose is administered
  2. Leads to a decreased physiological response when combined with another drug
  3. Instructions to a client regarding self-administration of oral enteric- coated tablets should include which of the following statements?
  4. “Avoid any other oral medicines while taking this drug.”
  5. “If swallowing this tablet is difficult, dissolve it in 3 ounces of orange juice.”
  6. “The tablet may be crushed if you have any difficulty taking it.”
  7. “To achieve best effect, take the tablet with at least 8 ounces of fluid.”
  8. The major reason for not crushing a sustained-release capsule is that, if crushed, the coated beads of the drugs could possibly result in:
  9. Disintegration
  10. Toxicity
  11. Malabsorption
  12. Deterioration
  13. Which of the following substances is the most likely to be absorbed in the intestines rather than in the stomach?
  14. Sodium bicarbonate
  15. Ascorbic acid
  16. Salicylic acid
  17. Glucose
  18. Which of the following variables is a factor in drug absorption? PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+

  1. An advantage of prescribing a sublingual medication is that the medication is: 1.^ Absorbed rapidly
    1. Excreted rapidly
    2. Metabolized minimally
    3. Distributed equally
  2. Drugs that use CYP 3A4 isoenzymes for metabolism may:
    1. Induce the metabolism of another drug
    2. Inhibit the metabolism of another drug 3. Both 1 and 2
    3. Neither 1 nor 2
  3. Therapeutic drug levels are drawn when a drug reaches steady state. Drugs reach steady state:
  4. After the second dose
  5. After four to five half-lives
  6. When the patient feels the full effect of the drug
  7. One hour after IV administration
  8. Upregulation or hypersensitization may lead to:
    1. Increased response to a drug
    2. Decreased response to a drug
    3. An exaggerated response if the drug is withdrawn
    4. Refractoriness or complete lack of response PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON

ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON TEST BANK GRADED A+ Chapter 2. Review of the Basic Principles of Pharmacology Answer Section MULTIPLE CHOICE

ANS

1 PTS: 1

ANS

3 PTS: 1

ANS

2 PTS: 1

ANS

3 PTS: 1

ANS

2 PTS: 1

ANS

1 PTS: 1

ANS

3 PTS: 1

ANS

4 PTS: 1

ANS

2 PTS: 1

PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE NURSE PRESCRIBERS ,QUESTIONS & ANSWERS FULLY ANALYSED EDITION EXAM 100% CORRECTLY/VERIFIED ANSWERS WITH SATISFACTION GUARANTEED SUCCESS LATEST UPDATE 2023 5TH EDITION WOO ROBINSON