Download Portage Learning NURS 231 Pathophysiology Module Exams and more Exams Nursing in PDF only on Docsity! PORTAGE LEARNING NURS 231 PATHOPHYSIOLOGY 2023 MODULE 1 - MODULE 10 EXAMS (LATEST UPDATE) PORTAGE LEARNING NURS 231 PATHOPHYSIOLOGY 2023 MODULE 1 - MODULE 10 EXAMS (LATEST UPDATE) RANKED A+ [Document title] ngure Portage Learning NURS 231 Pathophysiology PATHOPHYS Module Module 1 Exam Question 1 2.5 / 2.5 pts True/False: A bodybuilder’s muscles will display hyperplasia. True Correct! False It will display hypertrophy. Question 2 2.5 / 2.5 pts True/False: Barrett esophagus is an example of dysplasia. True Correct! False It’s metaplasia. Question 3 0 / 2.5 pts True/False: Hypertrophy is an increase in the size of an organ or tissue caused by an increase in the number of cells You Answered True Correct Answer False Question 4 2.5 / 2.5 pts True/False: [Document title] ngure 2 Question 7 1.67 / 2.5 pts Which of the following move across the cell membrane via diffusion? Select all that apply. Correct! 6 Oxygen Glucose Correct Answer Water Correct! Carbon dioxide Question 8 2.5 / 2.5 pts Multiple Choice Which of the following are false regarding cell communication? Endocrine signaling depends on hormones Neurotransmitters act through synapses G-protein linked receptors act through an on-off switch Correct! Paracrine signaling releases a chemical into the extracellular fluid that affects its own activity Question 9 2.5 / 2.5 pts Which is true of the cytoskeleton? Select all that apply. Correct! It controls shape and movement Correct! Cilia and flagella are microtubule-filled cellular extensions It includes peroxisomes and proteasomes Question 10 0 / 2.5 pts Multiple Choice High blood pressure is an example of which of the following? Pathology Correct Answer Pathophysiology Physiology You Answered No answer text provided. Question 11 2.5 / 2.5 pts Multiple Choice A patient has a fever and rash. What are these examples of? Correct! Signs Symptoms Both A & B Question 12 2.5 / 2.5 pts Multiple Choice Which of the following is true of a test’s sensitivity? It is how likely the same result will occur if repeated Correct! If negative, it can safely be assumed that the person does not have a disease It is considered a true-negative result It can only be calculated from people without the disease Question 13 2.5 / 2.5 pts Multiple Choice Which of the following is the effect of an illness on one’s life? Incidence Correct! swollen, and pulseless. The skin is moist, black, and under tension. Blebs form on the surface, liquefaction occurs, and a foul odor is caused by bacterial action. The spread of tissue damage is rapid. Question 17 10 / 10 pts Match the type of cell injury to the cause. Some answers may be used more than once. (1 point each) Sunburn a. Physical agents Obesity b. Radiation injury Reactive oxygen species c. Chemical injury Low oxygen to tissues d. Biologic agents Fractures e. Nutritional imbalances OTC drugs f. Free radical injury Hypothermia g. Hypoxic cell injury Radiation treatment Lead toxicity Bacteria Question 18 10 / 10 pts List the 4 types of tissue found in the body. Pick 2 and give a description and example of each. Your Answer: Epithelial, Connective, Muscle, and Nervous Epithelial tissue covers the body's outer surface, lines inner surfaces, forms glandular tissue. It is avascular and can be squamous, cuboidal, and columnar. An example of this type of tissue is our skin. Muscle tissue functions to move our bones, pump blood through the heart, as well as contract blood vessels. Cardiac muscle tissue is an example of muscle tissue. Epithelial tissue covers the body’s outer surface, lines the inner surfaces, and forms glandular tissue. Epithelial tissue has three distinct surfaces and the basal surface is attached to an underlying Question 1 3 / 3 pts True/False: Blood tests for tumor markers are the single best screening tool for cancer. Why or why not? Your Answer: False. Tumor markers, which can be used for establishig prognosis, monitoring treatment and detecting recurrent disease, have limitiations. Under benign situations, tumor markers can still be elevated. Whereas in early stages of malignancy, not elevated. They have a lack of specificity and are then limited in their ability to screen or diagnose accuratley. False, they are elevated in benign conditions, most are not elevated in the early stages of malignancy. Question 2 3 / 3 pts Tissue biopsy is of critical importance in what role? Your Answer: Play a critical role in histologic and cytologic studies for diagnosis of cancers. Diagnosing the correct cancer and histology. Question 3 4 / 4 pts 1. List two signs or symptoms a patient may present with that might indicate a cancer diagnosis: 2. What are two side effects commonly experienced by cancer patients? Your Answer: 1) Bleeding and/or weight loss 2) Anorexia, hair loss 1. Bleeding; sore that doesn’t heal; fluid in the pleural, pericardial, or peritoneal spaces; chest pain, shortness of breath, cough, abdominal discomfort or swelling. Other possible answers can include a mass or lump, pain (need to be specific), fatigue, fevers, weight loss 2. Weight loss, wasting of body fat and muscle tissue, weakness, anorexia, and anemia, fatigue, sleep disturbances Question 4 10 / 10 pts Explain the TNM system: Your Answer: TNM system is a detailed staging system, created by AJCC, is used by cancer facilites. It classifies cancers into stages using 3 tumor components; Tumor, Nodes, Metastasis. T is size and spread of the primary tumor. N is how involved the lymph nodes. M is the extent of metastatic involvement. Classification: Tx, T0, Tis, T1-4 Nx, N0, N1-3 Mx, M0, M1 T is the size and local spread of the primary tumor. N is the involvement of the regional lymph nodes. M is the extent of the metastatic involvement. Question 5 10 / 10 pts 1. When would surgery be appropriate in the treatment of cancer? 2. Most chemotherapeutic drugs cause pancytopenia due to bone marrow suppression. What are the 3 possible adverse outcomes of this? Your Answer: 1. Surgery can be used if the tumor is solid and small with well-defines margins. Also can be used to treat oncologic emergencies and be used as prophylactic measures. 2. 3 possible adverse outcomes are neutropenia, anemia, thrombocytopenia. 1. Surgery is often the first treatment for solid tumors. If the tumor is small with well-defined margins, it can be removed completely. It is also used for oncologic emergencies and prophylactic surgery in high risk patients. 2. Neutropenia- risk for infections Anemia- causing fatigue Thrombocytopenia- risk for bleeding Question 6 2.5 / 2.5 pts True/False: Cell proliferation is the process in which proliferating cells become more specialized cell types. True Correct! False False, cell differentiation Question 7 2.5 / 2.5 pts True/False: Cell differentiation is the process of increasing cell numbers by mitotic cell division. True Correct! False False, cell proliferation Question 8 2.5 / 2.5 pts What are two important properties that stem cells possess? Your Answer: Adenoma Melanoma Lymphoma Glioma Question 14 10 / 10 pts A 62-year-old man with a 30-pack year smoking history is diagnosed with small cell lung cancer with metastasis to the bone. (1) Explain the process of how cancer spreads metastatically. (2) What symptoms might he have presented with? (3) Which screening test would he have benefited from? Your Answer: 1. Metastasis is a multi-step process. Cancer cells breaks loose from the primary tumor and enters circulation via a blood vessel or lymp system. It finds a new favorable location to invade, grow, and establish blood supply. 2. Patient might have presented with shortness of breath, chest pain, and cough. 3. Patient would have benefited from a chest CT scan. (1) Metastasis- a cancer cell must break loose from the primary tumor, invade the surrounding extracellular matrix, gain access to a blood vessel, survive its passage in the bloodstream, emerge at a favorable location, invade the surrounding tissue, begin to grow, and establish a blood supply. (2) Chest pain, shortness of breath, cough, bone pain. (3) Yearly low-dose chest CT. Question 15 3 / 3 pts Benign tumors have which of the following characteristics? Select all that apply. Undifferentiated cells Correct! Portage Learning / NURS 231 Patho All Module Exams Question 19 3.5 / 3.5 pts Which of the following are risk factors for developing cancer? Select all that apply. Correct! HBV Correct! Alcohol Correct! High intake of smoked meats Deodorant Question 20 3.5 / 3.5 pts All of the following viral agents are correctly paired with the associated lesion except: Human papillomavirus (HPV): genital warts Correct! Epstein-Barr virus: carcinoma of the cervix Epstein Barr is linked to Burkitt lymphoma and nasopharyngeal cancer. Cervical carcinoma is linked to HPV. Hepatitis B virus: hepatocellular carcinoma Human herpes virus-8: Kaposi sarcoma Question 21 3 / 3 pts List one example of screening for each method: observation, palpation, and lab test/procedure: Your Answer: Observation: skin Palpation: breast Lab test: Pap smear Observation: skin, mouth, external genitalia Palpation: breast, thyroid, rectum and anus, prostate, lymph nodes Laboratory tests and procedures: Pap smear, colonoscopy, mammography MODULE 3 Question 1 5 / 5 pts Short answer Explain the challenges of diagnosing autoimmune disorders. Your Answer: Diagnosing is made by history, physical, and serological findings. Since some blood tests are more generic, results can be imprecise. Markers can be elevated in the presence of other diseases.Criteria for diagnosis: Evidence of an autoimmune reaction, immunological findings are not second to other conditions, and no other causes are found. There are over 80 identified, many with overlapping presentations. Many manifestations are nonspecific and are seen in other non-autoimmune diseases. Blood testing isn’t perfect either, as some tests are more generic and can be elevated in the presence of other diseases. Question 2 2.5 / 2.5 pts Multiple Choice: Which type of immunity is characterized by the development of a specific response to an antigen? Innate immunity Correct! Adaptive immunity Autoimmunity Active immunity Question 3 2.5 / 2.5 pts Multiple Choice: What allows the lymphocyte to differentiate between self and foreign molecules? Antigen presenting cells Regulatory cells Correct! Major histocompatibility complex (MHC) molecule Effector cells Question 4 0 / 3 pts T lymphocytes produce what type of immunity? Your Answer: Portage Learning / NURS 231 Patho All Module Adaptive immunity Cell-mediated Question 5 26 Portage Learning / NURS 231 Patho All Module Corneal ulceration Question 8 10 / 10 pts A 9-year-old boy with a peanut allergy was exposed to peanuts. He presents to the emergency room with an anaphylactic reaction. (1) What symptoms might he present with? (2) Does the quantity of exposure mean he will have a more severe reaction? (3) What is the initial immediate treatment? (4) What are 2 things people with anaphylaxis should always carry? Your Answer: 1) shortness of breath, skin redness/hives , abdominal cramping 2) quantity of the exposure does NOT play role on how severe the reaction can be 3) elimination of the food and EpiPen (epiniphereine) 4) carry 2 EpiPens (1) Any of the following reactions are accepted. Grade I: erythema and urticaria, with or without angioedema. Grade II: hypotension, tachycardia, dyspnea, and GI manifestations, like nausea, vomiting, diarrhea, and abdominal cramping from mucosal edema. Grade III: bronchospasm, cardiac dysrhythmias, and cardiac collapse. Grade IV: cardiac arrest (2) No (3) Epinephrine (4) identification about allergy, EpiPen Question 9 3.5 / 3.5 pts True/False: Following a heart attack, the area of heart muscle that has undergone necrosis because of lack of blood supply will heal by scar tissue replacement. Correct! True False Question 10 3 / 3 pts Multiple Choice: Which of the following is an incorrect pairing of a classic manifestation of acute inflammation with its corresponding cause? Rubor – vasodilation Correct! Dolor – inflammatory cells infiltrating sensory nerves 29 Portage Learning / NURS 231 Patho All Module 30 In acute inflammation, dolor (pain) is caused by increased hydrostatic pressure in tissues and by chemical mediators. Calor – increased blood flow Portage Learning / NURS 231 Patho All Module 31 Tumor – exudation of fluid and cells into extravascular tissues Question 11 3.5 / 3.5 pts True/False: Lymphocytes are categorized as either granulocytes or agranulocytes. True Correct! False false, leukocytes Question 12 3 / 3 pts True/False: Passive immunity is achieved through immunization. True Correct! False false, active immunity Question 13 2.5 / 2.5 pts True/False: B lymphocytes normally produce antibodies against host tissues. True Correct! False Question 14 3.5 / 3.5 pts Antibodies are also known as ? Your Answer: immunoglobulins immunoglobulins Portage Learning / NURS 231 Patho All Module 34 Short answer: What are autoantibodies? Your Answer: Portage Learning / NURS 231 Patho All Module 35 In autoimmune diseases, the immune sustem loses its ability to recognize self and produces autoantibodies, which act against host tissues Answer: In many autoimmune diseases, the immune system loses its ability to recognize self and produces what is called autoantibodies, which act against host tissues. Question 19 10 / 10 pts Short answer A 40-year-old man presents with cough and shortness of breath. After an H&P and chest films, it is determined he has pneumocystis carinii pneumonia (PCP). The provider does an HIV test, which is positive. Upon further testing, the man’s CD4+ cell count is 100 cells/µL and his viral load is 250,000 copies/mL. (1) Why did the provider do an HIV test after the man was diagnosed with PCP? (2) What classification does this man fall into based on his CD4+ count and symptomatology, and why? Your Answer: 1) PCP is a lung infection that affects people with weakened immune systems, such as those infected with HIV. It is listed as an opportunistic infection. 2) Overt AIDS. Patient's CD4+ cell count is below 200 cells/uL. Patient also presented with an AIDS- defining illness, such as PCP. (1) Opportunistic infections are those common organisms that do not produce infection without impaired immune function. (2) The last phase, or AIDS illness, occurs when the CD4+ cell count falls to less than 200 cells/µL or exhibits an AIDS-defining illness. The risk of opportunistic infections and death increases significantly when the CD4+ cell count falls below 200 cells/µL. Question 20 3.5 / 3.5 pts Multiple Choice: Which process is NOT included in wound healing? Inflammatory Proliferative Correct! Acute-phase response Remodeling Question 21 3.5 / 3.5 pts Multiple Choice: Portage Learning / NURS 231 Patho All Module 36 Which of the following cells is a permanent cell? Epidermal cell Portage Learning / NURS 231 Patho All Module Exams Question 26 0 / 2.5 pts Multiple Choice: The process of leukocyte accumulation in the cellular phase of acute inflammation is called what? You Answered Adhesion Transmigration Chemotaxis Correct Answer Margination Question 27 2.5 / 2.5 pts Multiple Choice: Which lab value will typically be increased in a viral infection? Neutrophils Eosinophils Basophils Correct! Lymphocytes MODULE 4 Question 1 2.5 / 2.5 pts Which of the following increases the chance of clotting? Select all that apply. Vitamin K deficiency Von Willebrand factor deficiency Correct! Protein C deficiency Thrombocytopenia Portage Learning / NURS 231 Patho All Module Exams Question 2 2.5 / 2.5 pts A deficiency in which of the following would lead to a hypercoagulable state? Select all that apply. Correct! Protein C Correct! Protein S Factor II Factor VII Factor IX Factor X Correct! Antithrombin III Question 3 2.5 / 2.5 pts Which of the following is a hypercoagulable state? Select all that apply. Hemophilia A Correct! Congestive heart failure Correct! Smoking Thrombocytopenia Correct! Postsurgical state Question 4 0 / 2.5 pts Which of the following is FALSE of disseminated intravascular coagulation (DIC)? Select all that apply. Microthrombi cause vessel occlusion and tissue ischemia You Answered Premature destruction of red cells Correct! Decrease in erythropoiesis Sickle cell disease and thalassemias are included Bone marrow is hyperactive Question 11 2.5 / 2.5 pts Which of the following are potential causes of a sickle crisis in sickle cell anemia? Select all that apply. Alkalosis Correct! Dehydration Correct! Cold exposure Correct! Physical exertion Question 12 0 / 2.5 pts Multiple Choice: A 23-year-old African-American man with a history of severe lifelong anemia requiring many transfusions has nonhealing leg ulcers and recurrent periods of abdominal and chest pain. These signs and symptoms are most likely to be associated with which one of the following laboratory abnormalities? Correct Answer Sickle cells on peripheral blood smear Loss of intrinsic factor You Answered Decreased erythropoietin Decreased ferritin Question 13 2.5 / 2.5 pts Multiple Choice: Portage Learning / NURS 231 Patho All Module Which of the following is NOT true of vitamin B12 deficiency anemia? 46 49 In stable angina, with exertion, the vessels cannot properly vasodilate. This can cause chest pain, tightness or shortness of breath. Heart is stable at rest, but cannot keep up with the exertion demand. It is relieved with rest and/or use of nitroglycerin. With increasing occlusion of the coronary vessel, the demands of the resting heart may become too great. Unstable agina is when patient has angina without exertion. Rest is insuffient, but can be releived with nitroglycerin. If the plaque ruptures, complete occulsion can occur. This can lead to lack of oxygen to tissues in the heart and muscle can die. This is myocardial infarction. Chest pain unrelieved by rest, sharp pain down left arm, vomitting are signs of distress. Emergency/hospital interventions are needed. With atherosclerotic disease, the coronary vessel lumens are narrowed and blood supply to the heart is diminished. With exertion, the vessels cannot adequately vasodilate. This can manifest as chest pain or tightness and/or shortness of breath. Stable angina- The heart is stable at rest but cannot keep up with the demand of exertion. Stable angina typically has a >70% stenosis of the coronary arteries. It is relieved by rest or nitroglycerin (vasodilator). Unstable angina- With increasing occlusion of the coronary vessel(s), the demands of the resting heart may become too great. When the patient experiences angina without exertion, or when the level of exertion necessary to cause anginal symptoms decreases, this is called unstable angina. It can be relieved by nitroglycerin, but not rest. Unstable angina means one or more coronary vessels is nearly totally occluded. Myocardial infarction- If a plaque ruptures, coronary thrombosis can cause complete occlusion. If collateral flow is inadequate, the tissue supplied becomes ischemic. Without oxygen, a portion of the muscle can die. MI can present as chest pain unrelieved by rest, sometimes radiating down the left ram or into the jaw or neck, dyspnea, nausea/vomiting, sweating, and/or other signs of distress. Other symptoms include a crushing pain or like “something is sitting on my chest.” Women may present with weakness, fatigue, shortness of breath, or GI complaints. Symptoms are not relieved by nitroglycerin. Question 19 10 / 10 pts 1. Name 2 lifestyle changes to prevent further progression of atherosclerotic diseases: 2. Name 2 medications used to treat someone with coronary artery disease and their mechanisms of action: Your Answer: 1. Stop smoking and frequent exercise 2. ACE inhibitors prevent conversion of angiotensin I to angiotensin II, which decreases vasocontriction, aldosterone production, sodium and water retiention by the kidneys. Diuretics promote the excretion of fluids, reducing preload. 1. Reduction in fat intake, quitting smoking, weight loss, exercise 2. Aspirin or other platelet inhibitors are used to prevent thrombosis formation. Beta-blockers and calcium channel blockers (CCB) – both decrease the heart rate and contractile force – can be initiated to decrease the heart’s demand of oxygen. CCB also increase coronary vasodilatation and decrease coronary vasospasm. Nitrates are used to quickly dilate the coronary vessels. Nitrates also dilate veins, decreasing the heart’s work by decreasing preload and afterload. Question 20 2.5 / 2.5 pts Multiple Choice: 50 With increasing occlusion of the coronary vessel(s), the demands of the resting heart may become too great. When the patient experiences angina without exertion, or when the level of exertion necessary to cause anginal symptoms decreases, this is called what? Stable angina Correct! Unstable angina Myocardial infarction Question 21 2.5 / 2.5 pts Multiple Choice: Which of the following is NOT a risk factor for hypertension? Correct! Increased potassium intake Increased salt intake Increased alcohol intake Increased caloric intake Question 22 2.5 / 2.5 pts Multiple Choice: Each of the following lifestyle modifications will help to decrease blood pressure except: Losing weight Increase fruits and vegetables Correct! 3 drinks or more of alcohol Limiting salt intake Question 23 2.5 / 2.5 pts 51 Multiple Choice: 54 Fill in the blank: The drug most commonly associated with inhibition of platelet aggregation is . Your Answer: aspirin aspirin Question 28 10 / 10 pts Patient is found to have the above: What risk factors mostly led to this disease state? What is this person at risk for developing? What lifestyle modifications would you suggest for them? Your Answer: 1. Smoking, poor diet, high cholesteral values, obesity, diabetes 2. Atherosclerosis 3. Stop smoking, exercise, dietary changes, reduce alcohol consumption Answer: Picture is of an atherosclerotic plaque Hyperlipidemia, cigarette smoking, obesity and visceral fat, hypertension, diabetes mellitus. Increasing age, family history of premature CHD, and male sex. May also include C- reactive protein (CRP) and serum lipoprotein(a). Coronary artery disease, angina, myocardial infarction, aneurysm, stroke (ischemia, thrombosis, emboli). Stop smoking, lose weight/exercise, healthy diet (low-fat, low-cholesterol), adhere to medication for blood pressure, hyperlipidemia, and/or diabetes. MODULE 5 Question 1 2.5 / 2.5 pts True/False: 55 Both carbon dioxide and oxygen are able to bind with hemoglobin. 56 Correct! True False Question 2 2.5 / 2.5 pts True/False: Exercise, allergens, and emotion can all contribute to an asthma attack. Correct! True False Question 3 2.5 / 2.5 pts The breathing rate is determined by input from that monitor oxygen, carbon dioxide, and pH levels in the blood. Your Answer: chemorecpetors chemoreceptors Question 4 2.5 / 2.5 pts The are the actual sites of gas exchange between the air and blood. Your Answer: alveoli alveoli Question 5 2.5 / 2.5 pts True/False: Asthma is considered reversible airway bronchoconstriction. Correct! True False Question 6 2.5 / 2.5 pts True/False: 59 Ventilation Question 11 1.5 / 2.5 pts 60 Which of the following cells contribute to airway inflammation in asthma? Select all that apply. Correct! Eosinophils Correct! Mast cells Correct Answer Neutrophils Correct Answer Leukotrienes Correct! Lymphocytes Question 12 2.5 / 2.5 pts Multiple Choice: Alpha-1 antitrypsin deficiency is most likely seen in which disease process? Bronchial asthma Chronic bronchitis Correct! Emphysema Bronchiectasis Question 13 2.5 / 2.5 pts Multiple Choice: Histologically, chronic bronchitis would exhibit each of the following except: Correct! Enlargement of the airspaces 61 Increase in goblet cells Fibrosis of the bronchiolar wall 64 An 18-year-old woman is admitted to the ER with a suspected drug overdose. Her respiratory rate is slow (4-6 breaths/minute) and shallow. Arterial blood gases reveal a PCO2 of 80 mm Hg and a PO2 of 60 mm Hg. What is the cause of this women’s high PCO2 and low PO2? Hypoventilation almost always causes an increase in PCO2. Explain. Your Answer: The patient has decreased ventilation, impaired alveolar ventilation. This causes an increase in plasma PCO2 and decrease in PO2. She cannot expire the air at a normal rate resulting in accumulation of CO2. Hypoventilation is when there is a reduced amount of air entering the lungs and alveoli. This results in decrease of oxygen and increase of CO2 in the blood. Breathing is often too shallow or too slow. Respiratory acidosis; with a decreased respiratory rate, you are not exhaling enough carbon dioxide and it accumulates. Question 17 10 / 10 pts Short answer: Explain why the oxygen flow rate for people with COPD is normally titrated to maintain the arterial PO2 between 60 and 65 mm Hg. Your Answer: Those with oxygen therapy, its vital not to supplement with too much oxygen. The respirator center in the medulla has adapted to elevated CO2 levels, no longer responding to increases in PCO2. A decrease in PO2 becomes the stimulus for respiration. If oxygen is given at too high of rate, the respiratory drive and stimulus is supressed. Their medullary respiratory center has adapted to the elevated CO2 levels and no longer responds to increases in PCO2. Therefore, a decrease in PO2 becomes the stimulus for respiration. If oxygen is given at too high of a rate, it suppresses the stimulus and the respiratory drive. Question 18 10 / 10 pts Short answer: 65 1.) Your patient’s lung showed the following: what is the only treatment that can delay the progression of this disease? 2.) Which is more soluble in plasma: carbon dioxide or oxygen? Your Answer: 1) Smoking cessation only treatment that slows disease progression 2) Carbon Dioxide 1.) smoking cessation 2.) Carbon dioxide Question 19 5 / 5 pts Short answer Some people have the triad of asthma, chronic rhinosinusitis, and nasal polyps. They have asthma attacks in response to taking what medication(s)? Your Answer: aspirin and other NSAIDs Aspirin and other NSAIDs 66 Question 20 5 / 5 pts Multiple Choice: Each of the following can lead to atelectasis except: Pleural effusion Tumor mass Correct! Thrombus Mucous plug Question 21 5 / 5 pts Multiple Choice: Each of the following are helpful treatments for COPD patients except: Oxygen therapy Bronchodilators Correct! Anticoagulants Pneumococcal vaccination Influenza vaccination 69 Correct! CN VI. Question 3 2.5 / 2.5 pts Multiple Choice: You are seeing a patient with Parkinson’s disease in your office. You notice they are repetitively rubbing their right thumb and forefinger. This is an example of what physical manifestation of the disease? Correct! Pill-rolling Cogwheeling Bradykinesia Rigidity Question 4 2.5 / 2.5 pts Multiple Choice: Sleep spindles are characteristic of which stage of sleep? Stage 1 Correct! Stage 2 Stage 3 Stage 4 Question 5 2.5 / 2.5 pts Multiple Choice: A person reports feelings of worthlessness and guilt as well as difficulty sleeping. As they are speaking, you notice a repetitive, accentuated blinking of their eyes. What type of depression are they experiencing? 70 Melancholic depression Atypical depression Depression with psychotic features Correct! Depression with catatonic features Question 6 2.5 / 2.5 pts Multiple Choice: Each of the following statements is true regarding the organization of the nervous system except: The PNS has an afferent and efferent division Correct! The somatic nervous system can be further divided into the sympathetic and parasympathetic divisions The CNS contains the hindbrain, midbrain, and forebrain The PNS contains the cranial nerves Question 7 2.5 / 2.5 pts Multiple Choice: Each of the following statements is true regarding Alzheimer’s disease except: Correct! Neurofibrillary tangles are a result of an abnormal accumulation of amyloid in the blood vessels Neuritic plaques are composed of deteriorating nerve pieces that arrange themselves around a sticky protein core called amyloid beta (Aβ) Cerebral amyloid angiopathy contributes to the pathogenesis of Alzheimer’s disease Question 8 2.5 / 2.5 pts Multiple Choice: Each of the following are modifiable behaviors related to stroke except: Obesity Question 12 2.5 / 2.5 pts Multiple Choice: Each of the following statements is true of Parkinson’s disease except: Correct! Environmental factors alone lead to disease development It affects the substantia nigra of the brain It is characterized by a loss of dopaminergic neurons Incidence increases with age Question 13 2 / 2 pts Fill in the blank: Efferent neurons deliver input from the CNS to the periphery. Your Answer: motor Answer: Motor Question 14 2 / 2 pts Fill in the blank: work by blocking membrane receptors and the subsequent reuptake of serotonin and norepinephrine. Your Answer: Tricyclic antidepressants, TCAs Answer: Tricyclic antidepressants (TCAs) Question 15 2 / 2 pts Fill in the blank: is sleep disordered breathing due to the brain not properly signaling the respiratory muscles. Your Answer: Central sleep apnea Answer: Central sleep apnea Question 16 2 / 2 pts Fill in the blanks: The aim of drug therapy used for Parkinson’s disease is to increase neuron activity or decrease neuron activity. Your Answer: dopaminergic, cholinergic Answer: dopaminergic, cholinergic Question 17 2 / 2 pts Fill in the blank: Connective tissue sheaths that surround the brain and spinal cord providing protection are called the . Your Answer: meninges Answer: Meninges Question 18 5 / 5 pts T/F – Make true if False Oligodendrocytes produce myelin in the PNS. Your Answer: False Answer: False, oligodendrocytes produce myelin in the CNS. Question 19 5 / 5 pts T/F – Make true if False The average age of onset for major depressive disorder is mid-30s; however, the age of onset is increasing in recent times. Your Answer: False Answer: False, the age of onset is decreasing in recent times. Question 20 5 / 5 pts T/F – Make true if False Brain activity is decreased during REM sleep. Your Answer: False Answer: False, brain activity is increased during REM sleep. Question 21 5 / 5 pts T/F – Make true if False Complete dependence for activities of daily living is characteristic of severe Alzheimer’s disease. Your Answer: day went on, the tingling sensation got worse, and they started to have difficulty speaking. The patient’s spouse reported that they were slurring their words. Past medical history includes a diagnosis of diabetes and hypercholesteremia. By the time they are evaluated, their symptoms start to subside. The tingling disappears and their speech returns to normal. What do you suspect this patient has experienced? What evidence is there to support that diagnosis? Your Answer: The patient experienced a TIA, transient ischemic attack, or mini stroke. The patient's symptoms, tingling sensation, slurred speech, difficulty speaking, are signs of a stroke. However, with TIA, the symptoms/signs, will resolve within 24 hours. The patient's medical history of diabetes and hypercholesteremia also are risk factors for stroke. Answer: This patient has experienced a TIA. They have experienced symptoms consistent with oxygen deprivation to the brain, however their symptoms subsided within 24 hours of their onset. Question 26 10 / 10 pts Long Answer Essay A 75-year-old male is brought to the emergency department via ambulance at 5 pm. The patient’s spouse reports that when they woke up (approximately at 6 am) he reported to her that he was having some blurred vision but decided to go about his day. As the day progressed, he started experiencing tingling and feelings of weakness on the entire left side of his body. He has a past medical history of diabetes. Based upon these symptoms and past medical history, what do you suspect this patient is experiencing? How would you confirm this diagnosis? What treatment should be administered? Explain why you chose that treatment. Your Answer: This patient is experiencing a stroke. A CT scan and MRI will be ordered to determine the type of stroke and rule out possible other disorders. A vasular image will be done to determine source of the block. Since its been over 4 hours since symptom onset, the window to safely administer tPA has passed. A catheter based method is necessary. This will mechanically break the clot and deliver drugs directly to the clot itself. A stent might be place as well. Answer: This patient is more than likely experiencing an ischemic stroke. A CT scan and MRI would be needed to determine if a clot was blocking blood flow to the brain tissue and to rule out a hemorrhagic stroke. If a clot is found, this patient would need to be re-perfused through catheter- base methods as they are outside of the 3-4.5 treatment window for the use of tPA drugs. Question 27 10 / 10 pts Long Answer Essay A patient is being seen in your office with a primary complaint of daytime fatigue that has lasted for the past 2 months. They go on to tell you that they are having difficulty with work performance and are constantly on edge. You suspect they have chronic insomnia. What are the 4 primary symptoms of insomnia? Describe a nonpharmacologic treatment plan that you can prescribe for this patient. Your Answer: The 4 symptoms are: DIfficulty initiating sleep Difficulty maintaining sleep Waking up too early Chronic nonrestorative (poor)sleep For a primary insomnia diagnosis, patient must exhibit at least 3 symptoms from the list above and at least one sympton during wake hours, such as poor work performance and irritability. Nonpharmacologic treatment will be patient education and good sleep hygiene, sleep habits. This includes a comfortable sleeping environmnet, going to bed at the same time each night, avoid caffeine or other stimulants several hours prior to bedtime, avoidance of screens before bed. Answer: The 4 primary symptoms of insomnia are: Difficulty initiating sleep Difficulty maintaining sleep Waking up too early Chronic nonrestorative or poor sleep You would educate the patient on proper sleep hygiene and encourage them to evaluate possible stressors that may need to be removed from their daily routine. Sleep hygiene involves the establishment of consistent sleep patterns (going to bed at the same time each night and only sleeping as long as one needs to feel refreshed during the day), creating a comfortable sleeping environment (optimal room temperature), avoidance of screens and excessive light right before bed, and finally, avoidance of stimulants (caffeine) several hours prior to normal bedtime. MODULE 7 Question 1 5 / 5 pts Multiple choice The liver is responsible for each of the following EXCEPT: Producing bile Stores vitamins and minerals Correct! Releases insulin Synthesizes protein Question 2 5 / 5 pts Multiple Choice: Complications of gallstones include each of the following EXCEPT: Correct! Cirrhosis pylori infection Family history of PUD NSAID use Alcohol use Correct! Stress Question 6 5 / 5 pts Multiple Choice Gastric ulcers are worsened by . Duodenal ulcers are worsened by . Correct! A. Eating; not eating B. Not eating; eating C. Both a & b D. None of the above Question 7 5 / 5 pts Multiple choice Each of the following are characteristics of ulcerative colitis EXCEPT: Correct! Granulomatous lesions Bloody diarrhea Pseudopolyps Risk of toxic megacolon Crypt abscess formation Question 8 5 / 5 pts Multiple Choice Each of the following are characteristics of Crohn disease EXCEPT: Fistulas and strictures Question 13 2.5 / 2.5 pts Short answer: What are the intermittent contractions that help to mix and move food along? Your Answer: Rhythmic movements Answer: Rhythmic movements Question 14 2.5 / 2.5 pts True/False Activation of the sympathetic nervous system increases amplitude of the slow waves. True Correct! False Question 15 2.5 / 2.5 pts Short Answer: lies between the mucosal and muscle layers of the intestinal wall, and is involved with controlling secretions, absorption, and contraction of each segment of the intestinal tract. Your Answer: Submucosal plexus Answer: Submucosal (Meissner) plexus Question 16 2.5 / 2.5 pts Short answer: What is it called when there is abnormally fast emptying of hyperosmotic gastric secretions? Your Answer: Dumping syndrome Answer: Dumping syndrome Question 17 5 / 5 pts Short answer Which GI hormone has strong growth hormone-releasing activity and stimulates food intake and digestive function? Your Answer: Ghrelin Portage Learning / NURS 231 Patho All Module Answer: Ghrelin 90 Portage Learning / NURS 231 Patho All Module Exams Question 18 5 / 5 pts Short answer: Which GI hormone inhibits gastric acid secretion? Your Answer: Secretin Answer: Secretin Question 19 5 / 5 pts True/False: Anti-diarrheal medication can be used with all types of diarrhea. True Correct! False Question 20 5 / 5 pts Fill in the blank: Consistently ignoring the urge to defecate can result in . Your Answer: constipation Answer: constipation Question 21 0 / 5 pts Multiple Choice: Clinical manifestations of cirrhosis include each of the following EXCEPT: Splenomegaly Correct Answer Choledocholithiasis Portal hypertension You Answered Coagulation factor deficiencies Encephalopathy Question 22 Portage Learning / NURS 231 Patho All Module decreased levels of ADH will lead to dilute urine. Alcohol inhibits ADH. Question 3 2.5 / 2.5 pts Which of the following statements is true regarding nephrons? It is divided into an outer medulla and an inner cortex It has 1 source of blood supply Correct! The glomerulus filters the blood while the tubule reabsorbs needed nutrients Question 4 0 / 2.5 pts Low Na+ levels in the plasma and interstitial compartment is characteristic of which of the following fluid imbalances? You Answered Dehydration Correct Answer Water intoxication Edema Question 5 2.5 / 2.5 pts Reabsorption in the PCT is characterized by the following except: Na+ and water are reabsorbed in equal proportions Correct! Glucose and amino acids are minimally reabsorbed in the PCT glucose and amino acids are almost completely reabsorbed in the PCT Sodium, chloride, potassium, and bicarbonate are 65%-80% reabsorbed from the filtrate Question 6 2.5 / 2.5 pts Which of the following is/are true regarding acid-base balance? (mark all that apply) 94 Correct! Acid-base balance refers to the balance of the concentration of hydrogen ions (H+) in the blood Acid-base balance refers to the balance of the concentration of bicarbonate ions (OH-) in the blood Venous blood is characterized by a more alkaline pH Correct! A higher concentration of H+ ions will decrease the pH of the blood Question 7 2.5 / 2.5 pts Acute postinfectious glomerulonephritis is characterized by the following except: Typically caused by a streptococcal infection Correct! Associated with a poor prognosis as it often leads to CKD the prognosis is good when underlying cause is treated Accompanied by glomerular enlargement and hypercellularity Oliguria is often the first symptom Question 8 2.5 / 2.5 pts Which of the following is characteristic of acute transplant rejection? Occurs months to years after transplant Correct! Involves increased T lymphocytes It does not respond well to immunosuppressive therapy Question 9 0 / 2.5 pts Which of the following is true of 25-hydroxycholecalciferol? You Answered It is the inactive form of vitamin D taken in through the skin via UV rays It is the inactive form of synthetic vitamin D