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Substance-related and Addictive Disorders, Exams of Health sciences

Substance use and addiction as complex diseases of the brain. It explains the symptoms of substance use and addiction, withdrawal, and the most common substances used by teens. The document also covers CNS depressants, amphetamines, tobacco/nicotine, and opioids. It provides information on the signs and symptoms of alcohol intoxication and withdrawal, including delirium tremens. The document also explains the assessment process and the medications used to treat withdrawal and abstinence.

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2022/2023

Available from 02/21/2023

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Download Substance-related and Addictive Disorders and more Exams Health sciences in PDF only on Docsity! 222 Week 6 Notes Substance-related and addictive disorders  Substance use o Not disorders of choice o Rather, complex diseases of the brain represented by  Craving  Seeking  Using regardless of consequences o Use of substance in larger amounts or over a longer period of time than intended o Continued desire or unsuccessful attempt to control substance use o Spends a considerable amount of time obtaining, using, or recovering from the effects of the substance o Continues to use substance regardless of social or interpersonal problem associated with substances use  Reduced or quits participation in social, occupational, or recreational activities o Use substance repeatedly in physically hazardous situations, such as driving impaired o Develops a tolerance to the substance  Requires additional amounts of the substance to achieve the desired effect or to become intoxicated o Exhibits manifestations of withdrawal o Feels strong urge to use the substance  Addiction o Primary, chronic disease of brain reward, motivation, memory, and related circuitry o A disease of dysregulation in the hedonic (pleasure-seeking) or reward pathway in the brain o Characterized by loss of control due to addition behavior  Participation continues despite continuing associated problems  A tendency to relapse back into the addictive behavior o Significant behaviors that lead in addictive disorders: non-substance related disorders  Gambling  The only non-substance related addictive disorder included in the DSM-5  Sexual activity  Shopping/spending  Internet use  Social media use  Gaming  Withdrawal – feelings of discomfort, distress, and intense craving for a substance that occurs when use of the substance or activity stops o Typical withdrawal symptoms  Cold shakes  Chills and sweating  Fever-like symptoms  Mood swings  Anxiety and depression  Bone pain  Vomiting  Insomnia  Diarrhea  Most common substances used by teens – “ All Moms Try Pretty Hard” o Alcohol o Marijuana o Tobacco o Prescription drugs o Hallucinogens  Bath salts o An ever-evolving drug, depending on chemical ingredients  Tweaking the drug but still maintain psychoactive properties o They can be purchased at convenience stores, gas stations, head shops, and on the internet  Sold as tablets, capsules, or powder in sealed envelopes o Euphoria and pleasurable “rush”  Tachycardia  Hypertension  Chest pain  Hallucinations  Paranoia  Psychosis o Bath salts are stimulants similar to o Referral to treatment: a nurse or other healthcare professional can suggest a referral for brief therapy or treatment for patients who screen positively  Assessment o Open-ended questions  Type of substance or addictive behavior  Pattern and frequency of substance use  Amount  Age at onset  Changes in occupational or school performance  Changes in use patterns  Periods of abstinence in history  Previous withdrawal manifestations  Date of last substance use/addictive behavior o Blackout or loss of consciousness o Changes in bowel movements o Weight loss or weight gain o Experience of stressful situation o Sleep problems o Chronic pain o Concern over substance use o Cutting down on consumption or behavior  Signs and symptoms are alcohol intoxication (blood alcohol level) o 20 – 100 mg = 0.02 – 0.1%  Mood and behavioral changes  Reduced coordination, impairment of ability to drive a car, or operate machinery o 101 – 200 mg = 0.101 – 0.2%  Reduced coordination of most activities  Speech impairment, trouble walking, general impairment of thinking and judgement o 201 – 300 mg = 0.201 – 0.3 %  Marked impairment of thinking, memory, and coordination  Marked reduction in level of alertness, memory blackouts, nausea and vomiting o 301 – 400 mg = 0.301 – 0.4%  Worsening of above symptoms with reduction of body temperature and blood pressure  Excessive sleeping  Amnesia o 401 – 800 mg = 0.401 – 0.8%  Difficulty walking the patient – coma  Serious decreased in pulse, temperature blood pressure, and rate of breathing  Urinary and bowel incontinence  Death o Alcohol produces relaxation, decreased social anxiety, maintaining calm o The legal intoxication level is set at 0.08% because of fine motor coordination and reaction times are measurably slow at that level o Blood alcohol level depends on many factors  Body weight  Gender  Concentration of alcohol in drinks  Number of drinks  Gastric absorption rate  Individual’s tolerance level  Signs and symptoms of alcohol withdrawal  assess Q2hr. within the first 48 hours  Q4hr assessment during the last 24 hours o Restlessness o Irritability o Anorexia (lack of appetite) o Tremor (shakiness within 24 hr.) o Insomnia (severe sign per ATI) o Impaired cognitive functions o Mild perceptual changes o Diaphoresis o Possible seizures – tonic clonic  Needs to be monitored closely  can lead to death  When to expect alcohol withdrawals o Signs usually start 4 to 12 hours of last intake o Peaks after 24 to 48 hours and the suddenly disappears o Delirium tremens = alcohol withdrawal delirium  May occur 2 to 3 days after last intake  May last 2 to 3 days  Medical emergency  Signs  Severe disorientation  Psychosis (hallucinations)  Severe hypertensions  Dysrhythmias  Delirium  Symptoms may progress to death  Treatment  Benzodiazepines – chlordiazepoxide, lorazepam o Chlordiazepoxide protocol – lasts 72 hours  First 48 hours  Q2 checks  Administer chlordiazepoxide 35 to 50 mg Q2hr PRN o Reassess within 30 to 45 min. o If ineffective, administer lorazepam 1 to 2 mg IM PRN  This will also help prevent seizures during serious withdrawal  Last 24 hours  Q4 checks  Medications for abstinence when withdrawal is over (days to weeks after withdrawal) o Disulfiram (Antabuse) – scheduled daily dose  aversion therapy  Patient will experience a headache first  Nausea and vomiting soon follows  Instruct the patient to avoid anything with alcohol  Mouthwash  Wearing cologne  Hand sanitizer  Vanilla extract o Naltrexone (ReVia)  PRN; also used to treat opioids addiction o Acomprosate – curve craving for ETOH  PRN  CNS depressants  Depression  Fatigue  Excess sleeping or insomnia  Dramatic unpleasant dreams  Psychomotor retardation or agitation  Possible SI (potential) o Amphetamines  Intended effect: increased energy, euphoria  Intoxication  Impaired judgement  Psychomotor agitation  Extreme irritability  Acute cardiovascular effects o Tachycardia o Elevated blood pressure  Withdrawal  Craving  Depression  Fatigue  Sleeping similar to those of cocaine o Tobacco/nicotine  Intended effect: relaxation, decreased anxiety  Long-term effects  Cardiovascular disease – hypertension, stroke  Respiratory disease – emphysema, lung cancer  Smokeless tobacco (snuff or chew) irritation to oral mucous membranes and cancer  Withdrawal  Abstinence syndrome o Irritability o Craving o Nervousness o Restlessness o Anxiety o Insomnia o Increased appetite o Difficulty concentrating o Anger o Depressed mood o Opioids  Intended effects: rush of euphoria, pain relief  Intoxication – “DIPSI”  Slurred speech  Impaired memory  Pupillary changes – pinpoint pupils (constrict)  Decreased respirations and LOC  Impaired judgement  Withdrawal  Abstinence syndrome o Sweating and rhinorrhea progressing to piloerection (goose bumps) o Tremors and irritability followed by severe weakness o Diarrhea o Fever o Insomnia o Pupil dilation o Nausea/vomiting o Pain in the muscles and bones o Muscle spasms  Withdrawal is very unpleasant but not life threatening  it is self-limiting to 7 days  Antidote: Nalaxone (Narcan)  Not the same as Naltrexone o Inhalants  Intended effects: euphoria  Examples  Nitrous oxide  Solvents  Intoxication – behavioral or psychological changes  Dizziness  Nystagmus  Uncoordinated movements or gait  Slurred speech  Drowsiness  Hyporeflexia  Muscle weakness  Diplopia  Stupor or coma  Respiratory depression and/or death  Withdrawal  none o Hallucinogens  Intended effects: heightened sense of self, altered perceptions (“more vivid colors”)  Examples  LSD  Peyote  PCP  Intoxication  Anxiety  Depression  Paranoia  Impaired judgement and social functioning  Pupil dilation  Tachycardia  Diaphoresis  Palpitations  Blurred vision  Tremors  Incoordination and panic attacks  Withdrawal  Hallucinogen persisting perception disorder o Visual disturbances or flashbacks o Hallucinations can occur intermittently for years  Nursing interventions  Acute metabolic: acidosis, alkalosis, electrolyte disturbances, hepatic failure, renal failure, hypoalbuminemia  Trauma: heat stroke, post-operative burns, fractures, prolonged immobilization  CNS abnormality: abscess, hemorrhage, increased intracranial pressure, seizures, stroke, tumors, vasculitis  Hypoxia: anemia, carbon monoxide poisoning, hypotension, heart failure, respiratory failure  Deficiencies: vitamins B-12, niacin, thiamine  Endocrinopathies: adrenal disorders, thyroiditis, uncontrolled diabetes  Acute vascular: hypertensive encephalopathy, shock, vasculitis, CNS-SLE  Toxins/drugs: medications, anticholinergic agents, pesticides, solvents  Heavy metals: lead, manganese, mercury  Delirium versus dementia o Delirium  Acute, rapid, over short period (hours to days)  Distractible  Speech is rambling, pressured, incoherent  Hallucinations/delusions (possible)  Restless, agitation, varies  Vital signs may be unstable  Personality changes rapidly  LOC fluctuates (sleep/wake)  Attention waves and wanes  Short lived, reversible  Develops rapidly  Recent source  Medical emergency  must determine the cause  UTI in older adults  delirium o Dementia  patient turns into a potato  Progressive, insidious (gradual deterioration, months or years)  Declines more steady  Sundowning – increased agitation seen more so in the afternoon to evening  Wandering, aggression  Vital signs are stable  Personality changes gradually  LOC unchanged  Irreversible  Profound loss/impairment in intelligence  Usually organic cause  Types of neurocognitive o Alzheimer’s disease (AD) – most common type  Commonly characterized by progressive deterioration of cognitive functioning  Formation of amyloid plaques  brain shrinks  Initial deterioration may be so subtle and insidious that others may not notice  In the early stages of the disease, the affected person may be able to compensate for loss of memory  Later on, symptoms become more obvious and start showing  Denial  Confabulation  Perseveration  Avoidance of questions  Stages of AD  Stage 1 – no impairment; normal function  Stage 2 – very mild cognitive decline o Minor memory problems o Forget where the keys are  Stage 3 – mild cognitive decline o The client may benefit from having someone live with them, to keep an eye on them o Might leave the door or fridge open  Stage 4 – moderate cognitive decline o Inability to maintain finances or pay bills  Stage 5 – moderately severe cognitive decline o Difficulty dressing o Assistance with ADLs  Stage 6 – severely cognitive decline o Loss of bladder control o Needs constant monitoring  Stage 7 – very severe cognitive decline o Loss of ability to swallow o Traumatic brain injury o Parkinson’s disease o Other disorders affecting the neurological system  Korsakoff’s syndrome or alcohol-induced persisting amnestic disorder – disturbance of short- term memory due to damage to the hippocampus  Alcoholic encephalopathy or Wernicke’s encephalopathy – a neurological disease characterized by ataxia, cranial nerve VI palsy, nystagmus, and confusion  Treated with thiamine  Basic medical workup o Chest and skull radiographic studies o Electroencephalography o Urinalysis o Sequential multiple analyzer 12-test serum profile o Thyroid function tests o Folate level o Venereal disease research laboratories (VDRL), human immunodeficiency virus (HUV) tests o Serum creatinine assay o Electrolyte assessment o Vitamin B12 level o Liver function tests o Vision and hearing evaluation o Neuroimaging, when diagnostic issues are not clear  Assessment o Aphasia – loss of language ability o Apraxia – loss of purposeful movement in the absence of motor or sensory impairment o Agnosia – loss of sensory ability to recognize objects o Confabulation o Perseveration o Memory impairment – initially the person has difficulty remembering recent events. Gradually, deterioration progresses to include both recent and remote memory o Disturbances in executive functioning – planning, organizing, abstract thinking o Agraphia – loss of the ability to write o Common medications used for dementia  Slow the progression of dementia  Donepezil (Aricept) 1997 – #1, Rivastigmine (Exelon) 1999, Galantomine (Razadyne) 2001  Taken at bedtime to reduce risk of fall and injury due to side effects of bradycardia and syncope  S/S o Diarrhea o Bradycardia o Nausea/vomiting o Syncope  Memantine (Namenda) 2003  Dizziness  Confusion  Constipation  Heart attack Family interventions  Overview of the family o The notion of family function refers to a range of characteristics. They include the family’s  Developmental needs  Response to stressors  Cultural concerns  Ability to interact with support services  Parenting skill  Relationships and interactions  Overall flexibility or resilience o Ability to provide for the physical and emotional safety of individual members o Quality of resources and support systems o Underlying issues, such as substance abuse, domestic violence, or chronic illnesses o Established patterns of behavior and interaction  Aside from the nuclear family, the following are identified types of families with children that exist in the United States o Single-parent family: one or more children who live with a single adult, male or female, related or unrelated to the children o Unmarried biological or adoptive family: one or more children who live with two parents who are not married to each other and are parents to all children in the family o Blended family: one or more children living with a biological or adoptive parent and an unrelated stepparent who are married to each other o Cohabitating family: one or more children living with a biological or adoptive parent and an unrelated adult who are cohabitating together o Extended family: one or more children living with at least one biological or adoptive parent and a related adult who is not a parent o “other” family: one or more children living with related or unrelated adults who are not biological or adoptive parents. This includes children living with grandparents and foster families  Family functions o A healthy family provides its members with tools to guide effective functioning within the family o Extends to functioning in other intimate relationships, the workplace, culture, and society in general o These tools are acquired through the activities associated with family life  Management activities  Communication patterns  Boundary delineation  Socialization  Emotional support  Overview of family therapy o Family systems theory posits that interventions aimed especially toward addressing family dynamics will  Decrease emotional reactivity  Encourage differentiation among individual family members  Improve patterns of family interaction o Changing dynamics in families are difficult to recognize when they occur slowly over time o The effective family therapist will demonstrate recognizing and response to family members’ anxieties and concerns  Family triangles o Triangulation describes an important and common relationship process that involves subsets of three family members o When the tension is dyad (two people) builds, a third person (child, friend, and parent) may be brought in by one of the members o The family triangle serves to stabilize interpersonal relationships in the short-term o Family triangles create emotional instability in the long run  Assessment o Families are inherently complex, and as a consequence, family assessment is complex as well o A variety of assessment tools are available to help nurses assess how the family functions as a unit and to identify individual members’ perceptions of how the family communications o Assessment in psychiatric nursing in general and particularly in work with families begins with nurses’ self-assessment o Nurses should be aware that their personal histories and styles of interactions might affect their responses to patients and their families as they express their feelings on the nursing unit  Diagnosis o Severe dysfunctional patterns can lead to physical or mental anguish among its members o A nurse’s understanding of family dynamic will foster appropriate planning and identification of diagnoses o Possible diagnosis  Risk for caregiver role strain  Caregiver role strain  Risk for impaired parenting  Readiness for enhanced parenting  Risk for impaired attachment  Dysfunctional family processes  Interrupted family processes  Readiness for enhanced family processes  Parental role conflict  Sexual dysfunction  Risk for compromised resilience  Ineffective denial  Ineffective family therapeutic regimen management  Deficient knowledge  Defensive coping  Outcome identification/goals of family therapy o Reduce dysfunctional behavior of individual family behaviors o Resolve or reduce intrafamily relationship conflicts o Encourage adaptive problem-solving behaviors o Improve family communication skills