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Pharmacology Practice Exam Questions and Answers 2024/2025, Exams of Medicine

Yale UniversityMedicine

A series of practice questions and answers related to pharmacology, covering various aspects such as drug mechanisms of action (moa), therapeutic uses, side effects, contraindications, and drug interactions. It includes questions on specific medications like atomoxetine, polymyxin b, ranitidine, oseltamivir, and others, testing knowledge of their clinical applications and potential adverse effects. The content is designed to assess understanding of pharmacological principles and their application in clinical practice, making it a valuable resource for students and healthcare professionals preparing for exams or seeking to reinforce their knowledge in pharmacology. Updated for 2024/2025.

Typology: Exams

2024/2025

Available from 06/11/2025

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3P practice exam | Actual Questions and Answers Latest Updated 2024/2025
(Graded A+)
atomoxetine (Strattera) - ✔✔The drug of choice for the treatment of attention deficit disorder in an
adolescent with a history of substance abuse.
The mechanism of action of polymyxin B / trimethoprim ophthalmic is: - ✔✔increased cell wall
permeability / inhibition of nucleic acid and protein
During pregnancy, the preferred choice for long-term treatment of gastroesophageal reflux is: -
✔✔ranitidine (Zantac)
Which medication may be used in infants for the treatment of functional constipation? - ✔✔MiraLax
A treatment regimen for acne will only be considered ineffective after consistent adherence for at least -
✔✔8 weeks
Dosing of oseltamivir (Tamiflu) for adults and adolescents with active influenza is administered orally -
✔✔75 mg bid x 5 days
Initial and routine monitoring of patients receiving Spirolactone (Aldactone) includes: - ✔✔serum
potassium, blood urea nitrogen and creatinine
Sertraline (Zoloft) is approved for the treatment of: - ✔✔panic disorder
The most commonly reported side effect of metronidazole and clarithromycin combination therapy for
H. pylori is: - ✔✔metallic taste
In the treatment of COPD, common side effects of corticosteroids may include: - ✔✔hypernatremia &
hypokalemia
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Download Pharmacology Practice Exam Questions and Answers 2024/2025 and more Exams Medicine in PDF only on Docsity!

3P practice exam | Actual Questions and Answers Latest Updated 2024/

(Graded A+)

atomoxetine (Strattera) - ✔✔The drug of choice for the treatment of attention deficit disorder in an adolescent with a history of substance abuse. The mechanism of action of polymyxin B / trimethoprim ophthalmic is: - ✔✔increased cell wall permeability / inhibition of nucleic acid and protein During pregnancy, the preferred choice for long-term treatment of gastroesophageal reflux is: - ✔✔ranitidine (Zantac) Which medication may be used in infants for the treatment of functional constipation? - ✔✔MiraLax A treatment regimen for acne will only be considered ineffective after consistent adherence for at least - ✔✔8 weeks Dosing of oseltamivir (Tamiflu) for adults and adolescents with active influenza is administered orally - ✔✔75 mg bid x 5 days Initial and routine monitoring of patients receiving Spirolactone (Aldactone) includes: - ✔✔serum potassium, blood urea nitrogen and creatinine Sertraline (Zoloft) is approved for the treatment of: - ✔✔panic disorder The most commonly reported side effect of metronidazole and clarithromycin combination therapy for H. pylori is: - ✔✔metallic taste In the treatment of COPD, common side effects of corticosteroids may include: - ✔✔hypernatremia & hypokalemia

The elimination phase of pharmacokinetics is the time it takes for the plasma concentration of the drug to decrease by - ✔✔50% When treating hirsutism associated with polycystic ovarian syndrome, the best treatment is: - ✔✔spirolactone (Aldactone) Which is a rapid acting insulin? - ✔✔Aspart (Novolog) Dynacin, used in the treatment of skin infections is the brand name for: - ✔✔minocycline The recommended treatment regimen for N. gonorrhea in pregnancy is: - ✔✔azithromycin (Zithromycin) 1 Gram orally PLUS ceftriaxone (Rocephin) 250mg IM To avoid reducing the effectiveness of doxycycline (Doryx) for the treatment of epididymitis, it should not be taken with : - ✔✔Carbamazepine (Tegretol) The use of SSRIs for the treatment of depression in older adults is associate with: - ✔✔falls and fractures The amino acid found in dairy products, fish and eggs is tyrosine. The amino acid from which tyrosine is made is: - ✔✔phenylalanine which of the following medications, when combined with pulmonary rehab enhances performance? - ✔✔tiotropium (Spiriva) Side effects of levonorgestrel (Plan B) to prevent pregnancy my include: - ✔✔nausea & vomiting Two black box warnings for ibuprofen (Motrin) are: - ✔✔CV thrombotic events and GI bleeding The duration of action for Optivar (azelastine) is: - ✔✔8 hours

Tretinoin topical gel (Atralin) should be used cautiously in patients who are allergic to : - ✔✔fish A 55-year old obese woman with DM2 has been receiving metformin and glimepiride daily at highest tolerated doses. Her most recent A1c is 9%. How should this be managed? - ✔✔Add a long-acting insulin at bedtime and continue metformin and glimepiride Which statement about naltrexone (Vivitrol) is correct? - ✔✔Naltrexone does not cause physical dependance Caution should be advised when taking zolpidem (Ambien) with: - ✔✔Phenergan Patients taking potassium sparing diuretics should be encourage to take medications with - ✔✔food or milk Which of the following medications or the treatment of acne is extended-release and dosed according to weight? - ✔✔minocycline (Miniocin) A patient was treated empirically with cipro for acute pylonephritis for 7 days and returns 2 weeks later with recurrent symptoms. The LEAST acceptable course of action is to: - ✔✔start gentamycin IM daily x 3 days, then cipro orally x 10 days Patients receiving oxcarbazepine (Trileptal) should be monitored for: - ✔✔hyponatremia When swithching a patient from immediate release guanfacine (Tenex) 1mg PO tid for treatment of ADD, to the extended release (Intuniv) : - ✔✔discontinue Tenex then begin Intuniv at the lowest dose and titrate up weekly Patients who require oral corticosteroids for the treatment of Bells Palsy should be instructed to take the medication with - ✔✔FOOD Which of the following enzymes DOES NOT affect the first pass effect of an oral medication? - ✔✔salivary enzymes

Addreall & Mydayis generic name - ✔✔amphetamine / dextroamphetamine Pharmodynamic interactions that occur when 2 drug act on distinct receptors is known as: - ✔✔heterodynamic competitors A patient has pertussis and is allergic to macrolides, so she is being treated with trimethoprim/sulfamethoxazole (Bactrim). She needs to be monitored for: - ✔✔baseline BUN, CBC, lytes MOA of clavulanate: - ✔✔bind to beta lactamase, hindering enzymatic activity Common side effect of pregabalin (Lyrica) - ✔✔edema & weight gain Promethazine (Phenergan) , a 1st gen antihistamine, is contraindicated in a patient with: - ✔✔Asthma At each follow u visit patients taking carbidopa/levodopa (Sinemet), the provider should inquire about: - ✔✔sudden onset of sleep, gambling or sexual impulses A few first generation cephalosporins, (Keflex) cover some gram negative against - ✔✔E Coli The most common short term adverse effect of ropinirole (Requip) used to treat restless leg syndrome, is: - ✔✔nausea, vomiting and fatigue Naltrexone (Vivitrol) does NOT affect alcohol addiction by: - ✔✔reducing the physical effects of ETOH Inside the brain, acetylcholine has as effect on a patients - ✔✔memory Progestin only "mini pill" are contraindicated in women: - ✔✔with pulmonary HTN