Safety Data Sheet for Acetaminophen by Cayman Chemical Co., Study notes of Printing

A Safety Data Sheet (SDS) for the research use of Acetaminophen, a chemical compound identified by its CAS Number 103-90-2 and EC number 203-157-5. The SDS provides information on the product identifier, supplier details, hazard identification, composition, first-aid measures, toxicological information, ecological information, transport information, and regulatory compliance. It also includes hazard statements, signal words, and hazard pictograms as per the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).

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2021/2022

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Safety Data Sheet
acc. to OSHA HCS
Printing date 02/15/2022 Revision date 02/15/2022
53.1.21
*
1 Identification
ยท Product identifier
ยท Trade name: Acetaminophen
ยท Article number: 10024
ยท CAS Number:
103-90-2
ยท EC number:
203-157-5
ยท Application of the substance / the mixture
This product is for research use - Not for human or veterinary diagnostic or therapeutic use.
ยท Details of the supplier of the safety data sheet
ยท Manufacturer/Supplier:
Cayman Chemical Co.
1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
USA
ยท Information department: Product safety department
ยท Emergency telephone number:
During normal opening times: +1 (734) 971-3335
US/CANADA: 800-424-9300
Outside US/CANADA: 703-741-5970
*
2 Hazard(s) identification
ยท Classification of the substance or mixture
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GHS07
Acute Tox. 4 H302 Harmful if swallowed.
Skin Irrit. 2 H315 Causes skin irritation.
Eye Irrit. 2A H319 Causes serious eye irritation.
STOT SE 3 H335 May cause respiratory irritation.
ยท Label elements
ยท GHS label elements
The substance is classified and labeled according to the Globally Harmonized System (GHS).
(Contd. on page 2)
US
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Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

  • (^) 1 Identification

ยท Product identifier

ยท Trade name: Acetaminophen

ยท Article number: 10024 ยท CAS Number: 103-90- ยท EC number: 203-157- ยท (^) Application of the substance / the mixture This product is for research use - Not for human or veterinary diagnostic or therapeutic use. ยท (^) Details of the supplier of the safety data sheet ยท Manufacturer/Supplier: Cayman Chemical Co. 1180 E. Ellsworth Rd. Ann Arbor, MI 48108 USA

ยท Information department: (^) Product safety department ยท Emergency telephone number: During normal opening times: +1 (734) 971- US/CANADA: 800-424- Outside US/CANADA: 703-741-

  • (^) 2 Hazard(s) identification

ยท (^) Classification of the substance or mixture

d~

GHS

Acute Tox. 4 H302 Harmful if swallowed. Skin Irrit. 2 H315 Causes skin irritation. Eye Irrit. 2A H319 Causes serious eye irritation. STOT SE 3 H335 May cause respiratory irritation. ยท (^) Label elements ยท GHS label elements The substance is classified and labeled according to the Globally Harmonized System (GHS). (Contd. on page 2) US

Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

Trade name: Acetaminophen

(Contd. from page 1) ยท Hazard pictograms

d~

GHS

ยท (^) Signal word Warning ยท Hazard statements H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. ยท Precautionary statements P261 Avoid breathing dust/fume/gas/mist/vapors/spray P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves / eye protection / face protection. P301+P312 If swallowed: Call a poison center/doctor if you feel unwell. P330 Rinse mouth. P302+P352 If on skin: Wash with plenty of water. P321 Specific treatment (see on this label). P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P337+P313 If eye irritation persists: Get medical advice/attention. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. ยท Classification system: ยท (^) NFPA ratings (scale 0 - 4)

2

0 0

Health = 2 Fire = 0 Reactivity = 0

ยท HMIS-ratings (scale 0 - 4)

HEALTH FIRE REACTIVITY

0 0

Health = * Fire = 0 Reactivity = 0

ยท Other hazards ยท Results of PBT and vPvB assessment ยท PBT: (^) Not applicable. ยท vPvB: Not applicable. US (Contd. on page 3)

Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

Trade name: Acetaminophen

(Contd. from page 3) See Section 8 for information on personal protection equipment. See Section 13 for disposal information. ยท Protective Action Criteria for Chemicals ยท PAC-1: Substance is not listed.

ยท PAC-2: Substance is not listed.

ยท PAC-3: Substance is not listed.

  • (^) 7 Handling and storage

ยท Handling: ยท Precautions for safe handling Ensure good ventilation/exhaustion at the workplace. ยท Information about protection against explosions and fires: (^) No special measures required.

ยท Conditions for safe storage, including any incompatibilities ยท Storage: ยท (^) Requirements to be met by storerooms and receptacles: No special requirements. ยท Information about storage in one common storage facility: Not required. ยท (^) Further information about storage conditions: Keep receptacle tightly sealed. ยท Specific end use(s) No further relevant information available.

  • (^) 8 Exposure controls/personal protection

ยท Additional information about design of technical systems: No further data; see item 7.

ยท Control parameters ยท Components with limit values that require monitoring at the workplace: (^) Not required. ยท Additional information: The lists that were valid during the creation were used as basis.

ยท Exposure controls ยท (^) Personal protective equipment: ยท General protective and hygienic measures: Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. ยท (^) Breathing equipment: In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air. ยท Protection of hands:

_S

Protective gloves

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation (Contd. on page 5) US

Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

Trade name: Acetaminophen

(Contd. from page 4) ยท Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. ยท (^) Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. ยท Eye protection:

_R

Tightly sealed goggles

  • (^) 9 Physical and chemical properties

ยท (^) Information on basic physical and chemical properties ยท General Information ยท (^) Appearance: Form: Solid Color: White ยท Odor: Characteristic ยท Structural Formula C8H9NO ยท Molecular Weight (^) 151.2 g/mol ยท Odor threshold: Not determined. ยท Formulation (^) A solution in Methanol

ยท pH-value: (^) Not applicable.

ยท (^) Change in condition Melting point/Melting range: 168 ยฐC (334.4 ยฐF) Boiling point/Boiling range: 64.7 ยฐC (148.5 ยฐF) ยท (^) Flash point: Not applicable.

ยท (^) Flammability (solid, gaseous): Product is not flammable.

ยท (^) Decomposition temperature: Not determined.

ยท (^) Auto igniting: Not determined.

ยท (^) Danger of explosion: Product does not present an explosion hazard.

ยท (^) Explosion limits: Lower: 5.5 Vol % Upper: 44 Vol %

ยท Vapor pressure: Not applicable.

ยท Density at 20 ยฐC (68 ยฐF): 0.83 g/cmยณ (6.92635 lbs/gal) ยท Relative density (^) Not determined. ยท Vapor density Not applicable. ยท Evaporation rate (^) Not applicable.

ยท (^) Solubility in / Miscibility with Water at 20 ยฐC (68 ยฐF): 14.2 g/l

ยท Partition coefficient (n-octanol/water): Not determined. (Contd. on page 6) US

Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

Trade name: Acetaminophen

(Contd. from page 6) ยท Behavior in environmental systems: ยท (^) Bioaccumulative potential No further relevant information available. ยท Mobility in soil No further relevant information available. ยท (^) Additional ecological information: ยท General notes: Water hazard class 1 (Assessment by list): slightly hazardous for water Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. ยท (^) Results of PBT and vPvB assessment ยท PBT: Not applicable. ยท (^) vPvB: Not applicable. ยท Other adverse effects No further relevant information available.

  • (^) 13 Disposal considerations

ยท Waste treatment methods ยท (^) Recommendation: Must not be disposed of together with household garbage. Do not allow product to reach sewage system. ยท (^) Uncleaned packagings: ยท Recommendation: Disposal must be made according to official regulations.

  • (^) 14 Transport information

ยท UN-Number ยท (^) DOT, IMDG, IATA UN

ยท (^) UN proper shipping name ยท DOT, IATA Environmentally hazardous substance, solid, n.o.s. (4- Acetamidophenol) ยท (^) IMDG ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (4-Acetamidophenol), MARINE POLLUTANT ยท (^) Transport hazard class(es)

ยท (^) DOT

dcp`รณ

ยท Class 9 Miscellaneous dangerous substances and articles ยท (^) Label 9

ยท (^) IMDG, IATA

dcp`รณdรขยด

ยท Class 9 Miscellaneous dangerous substances and articles ยท Label (^) 9 (Contd. on page 8) US

Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

Trade name: Acetaminophen

(Contd. from page 7) ยท (^) Packing group ยท DOT, IMDG, IATA III

ยท Environmental hazards: ยท (^) Marine pollutant: Symbol (fish and tree) ยท Special marking (IATA): Symbol (fish and tree)

ยท Special precautions for user Warning: Miscellaneous dangerous substances and articles ยท (^) Hazard identification number (Kemler code): 90 ยท EMS Number: F-A,S-F ยท (^) Stowage Category A ยท Stowage Code SW23 When transported in BK3 bulk container, see 7.6.2.12 and 7.7.3.9.

ยท Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable.

ยท Transport/Additional information:

ยท DOT ยท Quantity limitations (^) On passenger aircraft/rail: 400 kg On cargo aircraft only: 400 kg ยท (^) IMDG ยท Limited quantities (LQ) 5 kg ยท (^) Excepted quantities (EQ) Code: E Maximum net quantity per inner packaging: 30 g Maximum net quantity per outer packaging: 1000 g ยท (^) IATA ยท Remarks: When sold in quantities of less than or equal to 1 mL, or 1 g, with an Excepted Quantity Code of E1, E2, E4, or E5, this item meets the De Minimis Quantities exemption, per IATA 2.6.10. Therefore packaging does not have to be labeled as Dangerous Goods/Excepted Quantity. ยท UN "Model Regulation": (^) UN 3077 ENVIRO NMENT ALLY HAZARDO US S U B S T A N C E , S O L I D , N. O. S. ( 4 - ACETAMIDOPHENOL), 9, III

  • (^) 15 Regulatory information

ยท Safety, health and environmental regulations/legislation specific for the substance or mixture No further relevant information available. ยท Sara ยท (^) Section 355 (extremely hazardous substances): Substance is not listed. ยท (^) Section 313 (Specific toxic chemical listings): Substance is not listed.

ยท TSCA (Toxic Substances Control Act): ACTIVE (Contd. on page 9) US

Safety Data Sheet

acc. to OSHA HCS

Printing date 02/15/2022 Revision date 02/15/

Trade name: Acetaminophen

(Contd. from page 9) Skin Irrit. 2: Skin corrosion/irritation โ€“ Category 2 Eye Irrit. 2A: Serious eye damage/eye irritation โ€“ Category 2A STOT SE 3: Specific target organ toxicity (single exposure) โ€“ Category 3 ยท *** Data compared to the previous version altered.** US