ANCC exam 3(Leaner Friendly), Exams of Advanced Education

ANCC EXAM 3 2026(WELL PREPARED AND LEARNER FRIENDLY) 1. Infant GERD Management A 9-month-old female infant presents to the clinic for a routine well-child visit. Six months ago, she was prescribed omeprazole (Prilosec) due to gastroesophageal reflux and poor weight gain. At the present visit, her parents report she is drinking approximately 24 ounces of formula daily and eating some solid foods. They report no current reflux symptoms, and her growth chart shows steady and appropriate weight gain over the past 6 months. What is the next best step in management? A. Continue omeprazole (Prilosec) as prescribed B. Decrease the dose of omeprazole (Prilosec) and reevaluate in 3 weeks C. Discontinue omeprazole (Prilosec) and prescribe metoclopramide (Reglan) D. Discontinue omeprazole (Prilosec) and reevaluate in 3 months Correct Answer: B. Decrease the dose of omeprazole (Prilosec) and reevaluate in 3 weeks 2. Abdominal Aortic Aneurysm Screening

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2025/2026

Available from 03/14/2026

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ANCC EXAM 3 2026(WELL PREPARED AND LEARNER FRIENDLY)
1. Infant GERD Management
A 9-month-old female infant presents to the clinic for a routine well-child visit. Six months ago,
she was prescribed omeprazole (Prilosec) due to gastroesophageal reflux and poor weight gain.
At the present visit, her parents report she is drinking approximately 24 ounces of formula daily
and eating some solid foods. They report no current reflux symptoms, and her growth chart
shows steady and appropriate weight gain over the past 6 months.
What is the next best step in management?
A. Continue omeprazole (Prilosec) as prescribed
B. Decrease the dose of omeprazole (Prilosec) and reevaluate in 3 weeks
C. Discontinue omeprazole (Prilosec) and prescribe metoclopramide (Reglan)
D. Discontinue omeprazole (Prilosec) and reevaluate in 3 months
Correct Answer:
B. Decrease the dose of omeprazole (Prilosec) and reevaluate in 3 weeks
2. Abdominal Aortic Aneurysm Screening
A 70-year-old man presents for a routine checkup. He has a 40-pack-year smoking history but
reports no symptoms today.
What is the most appropriate recommendation regarding abdominal aortic aneurysm
screening?
A. Advise him to quit smoking but defer screening since he is asymptomatic
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ANCC EXAM 3 2026(WELL PREPARED AND LEARNER FRIENDLY)

  1. Infant GERD Management A 9-month-old female infant presents to the clinic for a routine well-child visit. Six months ago, she was prescribed omeprazole (Prilosec) due to gastroesophageal reflux and poor weight gain. At the present visit, her parents report she is drinking approximately 24 ounces of formula daily and eating some solid foods. They report no current reflux symptoms, and her growth chart shows steady and appropriate weight gain over the past 6 months. What is the next best step in management? A. Continue omeprazole (Prilosec) as prescribed B. Decrease the dose of omeprazole (Prilosec) and reevaluate in 3 weeks C. Discontinue omeprazole (Prilosec) and prescribe metoclopramide (Reglan) D. Discontinue omeprazole (Prilosec) and reevaluate in 3 months Correct Answer: B. Decrease the dose of omeprazole (Prilosec) and reevaluate in 3 weeks
  2. Abdominal Aortic Aneurysm Screening A 70-year-old man presents for a routine checkup. He has a 40-pack-year smoking history but reports no symptoms today. What is the most appropriate recommendation regarding abdominal aortic aneurysm screening? A. Advise him to quit smoking but defer screening since he is asymptomatic

B. No screening necessary, as he is beyond the recommended age C. Order an abdominal ultrasound for screening today D. Perform a physical exam to assess for a pulsatile mass Correct Answer: C. Order an abdominal ultrasound for screening today

  1. Secondary Amenorrhea Evaluation Which is the most important first step when evaluating a 15-year-old girl with 4 months of secondary amenorrhea? A. Checking weight B. Measuring FSH C. Measuring human chorionic gonadotropin levels D. Measuring TSH Correct Answer: C. Measuring human chorionic gonadotropin levels
  2. P Value Definition While reading a research article, a nurse practitioner notes a P value of 0.03. What does the P value represent?

Which finding indicates effective management? A. 1-hour postprandial glucose < 200 mg/dL B. 2-hour postprandial glucose < 100 mg/dL C. Daily fasting glucose < 95 mg/dL D. Weight loss of 2 lb since the last visit Correct Answer: C. Daily fasting glucose < 95 mg/dL

  1. Postmenopausal Bleeding A 62-year-old woman with postmenopausal bleeding presents with spotting for 2 weeks. Menopause occurred 8 years ago. What is the most likely diagnosis? A. Bladder cancer B. Endometrial carcinoma C. Ovarian fibroma D. Rectal adenocarcinoma Correct Answer: B. Endometrial carcinoma
  1. SSRI Side Effects A 40 - year-old man starts an SSRI for depression. Which side effect should be discussed? A. Insomnia improves if taken at bedtime B. Nausea typically resolves in 1 – 3 weeks C. Sexual dysfunction is irreversible D. Weight loss should be expected Correct Answer: B. Nausea typically resolves in 1 – 3 weeks
  2. Research Ethics Before beginning a study on a dietary supplement, what must occur first? A. Design a marketing strategy B. Ensure publication in a journal C. Obtain Institutional Review Board approval D. Secure pharmaceutical funding Correct Answer: C. Obtain Institutional Review Board approval

A. Café-au-lait spots B. Congenital dermal melanocytosis C. Milia D. Salmon patch Correct Answer: A. Café-au-lait spots

  1. Infant Anemia Screening A 12-month-old exclusively breastfed infant has Hb 10.5 g/dL. What is the best next step? A. Complete focused history and dietary assessment B. Order serum ferritin C. Prescribe iron supplementation D. Refer for lead chelation Correct Answer: A. Complete focused history and dietary assessment
  2. Prostatitis Antibiotic Contraindication Which condition is a contraindication to ciprofloxacin?

A. Hyperkalemia B. Lymphoma C. Myasthenia gravis D. Myocardial infarction Correct Answer: C. Myasthenia gravis

  1. Osteopenia Management A DXA T-score −1.5 indicates osteopenia. Best initial management? A. Encourage weight-bearing exercise and vitamin D/calcium B. No intervention C. Prescribe alendronate D. Prescribe denosumab Correct Answer: A. Encourage weight-bearing exercise and vitamin D and calcium
  2. Beta-Thalassemia Diagnosis Which test confirms beta-thalassemia?

A. Do you take your medications regularly? B. How do you feel about the changes you need to make? C. Is there a specific diet you’re considering? D. You should reduce your salt intake, right? Correct Answer: B. How do you feel about the changes you need to make?

  1. Medicare Electronic Prescribing Which Medicare plan supports electronic prescribing? A. Part A B. Part B C. Part C D. Part D Correct Answer: D. Part D
  2. Postpartum Contraception Best option for a breastfeeding mother immediately postpartum? A. Diaphragm B. Estrogen patch

C. Depo-Provera D. Norethindrone Correct Answer: D. Norethindrone

  1. Appendicitis Sign Pain in RLQ when LLQ is palpated is called: A. Dunphy sign B. Markle sign C. Psoas sign D. Rovsing sign Correct Answer: D. Rovsing sign
  2. Nasolacrimal Duct Obstruction Best management for a 2-week-old infant with excessive tearing? A. Lacrimal sac massage B. Ofloxacin drops C. Oral amoxicillin D. Ophthalmology referral

C. Legal ability to prescribe medications

  1. Acanthosis Nigricans Evaluation Best diagnostic test? A. HbA1c B. Skin biopsy C. Testosterone D. Vitamin A Correct Answer: A. HbA1c level
  2. Dog Bite Closure Which wound can be primarily closed? A. Deep elbow wound B. Lip laceration crossing vermillion border C. Puncture wound on hand D. Foot wound Correct Answer: B. Lip laceration crossing vermillion border
  1. Highest Level of Evidence Which study design provides the highest quality evidence? A. Case study B. Cohort study C. Qualitative study D. Randomized controlled trial Correct Answer: D. Randomized controlled trial
  2. Human Bite Tetanus Patient last Tdap age 19. Best next step? A. Td booster B. Tdap booster C. Tetanus immune globulin D. No treatment Correct Answer: A. Administer Td booster