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An arterial line is a thin catheter inserted into an artery. Arterial line placement is a common procedure in various critical care settings. It is most commonly used in intensive care medicine and anesthesia to monitor blood pressure directly and in real time (rather than by intermittent and indirect measurement, like a blood pressure cuff) and to obtain samples for arterial blood gas analysis. There are specific insertion sites, trained personnel and procedures for arterial lines. There are also specific techniques for drawing a blood sample from an A-Line or arterial line.
An arterial line is usually inserted into the radial artery in the wrist, but can also be inserted into the brachial artery at the elbow, into the femoral artery in the groin, into the dorsalis pedis artery in the foot, or into the ulnar artery in the wrist. In both adults and children, the most common site of cannulation is the radial artery, primarily because of the superficial nature of the vessel and the ease with which the site can be maintained. Additional advantages of radial artery cannulation include the consistency of the anatomy and the low rate of complications.
After the radial artery, the femoral artery is the second most common site for arterial cannulation. One advantage of femoral artery cannulation is that the vessel is larger than the radial artery and has stronger pulsation. Additional advantages include decreased risk of thrombosis and of accidental catheter removal, though the overall complication rate remains comparable.
There has been considerable debate over whether radial or femoral arterial line placement more accurately measures blood pressure and mean arterial pressure, however, both approaches seem to perform well for this function. In determining the need for and optimal location of arterial line placement, one must consider the risk and benefits of the procedure for each patient. A golden rule is that there has to be collateral circulation to the area affected by the chosen
There are multiple people that perform arterial line insertions. Cardiologists/cardiac surgeons, critical care doctors, anesthesiologists, emergency doctors, thoracic surgeons, registered nurses specially trained in arterial lines and certified nurse anesthetists may all insert arterial lines.
When placing an arterial line, make sure to follow these steps to successfully facilitate placement of an arterial line:
● Anticipation of hemodynamic instability ● Titration of vasoactive drugs ● Frequent blood sampling ● Respiratory failure including respiratory failure due to severe asthma or pulmonary edema ● Morbid obesity (unable to fit an appropriately sized NIBP cuff). Calibrating (zeroing) the arterial line has specific steps. First, ensure the transducer pressure tubing and flush solution are correctly assembled and free of air bubbles. Next, place transducer at level of the right atrium, make sure it is off to patient (open to air), press zero – this sets atmospheric pressure as zero reference point and whenever patient position is altered the transducer height should be altered. There are multiple conditions that must be met to ensure accuracy. First, make sure cannula is properly placed within the lumen of an unobstructed artery (i.e. No spasm, thrombus, atheroma proximal to cannula). Make sure cannula is not kinked or obstructed, cannula connected by short, rigid, wide-bore tubing to the transducer, no air bubbles in tubing or transducer, interface from fluid to transducer accurately transmits deflections, transducer has adequate frequency response (natural frequency >100Hz, transducer is leveled and zeroed to desired point (i.e. left atrium), no zero drift and monitor calibrated accurately.
There are multiple common sources of error. Look for bubbles in catheter-transducer system – decreased resonant
frequency, clotting in arterial catheter, elastic walls causes increased damping, and cannula won’t flush due to kinked or clotted line.
An arterial line can measure much more than blood pressure. Arterial lines can measure pulse rate and rhythm, effects of dysrhythmias on perfusion, ECG lead disconnection, continuous cardiac output using pulse contour analysis, specific wave form morphologies that might be diagnostic, pulse pressure variation and steeper upstroke of pulse pressure.
There are multiple complications associated with arterial lines. Insertion is often painful; an anesthetic such as lidocaine can be used to make the insertion more tolerable and to help prevent vasospasm, thereby making insertion of the arterial line somewhat easier. Aside from pain, other complications include, thrombosis and distal ischaemia, infection, increased diagnostic blood loss and anemia, retrograde air embolism, inadvertent drug/air injection, haematoma, retroperitoneal haematoma (femoral), bowel obstruction (femoral), vessel damage may lead to stricture and prevent future AV fistula formation for haemodialysis and pseudo-aneurysm.
Zeroing the arterial line helps to give the most accurate reading possible. First, close off the line to the patient (so that no air goes inside while zeroing) and then open the line up to air. This allows the pressure reading to be set at atmospheric pressure as your reference point for monitoring blood pressure or central venous pressure. Having an accurate atmospheric
When removing the arterial line, gather necessary removal equipment. You will need non-sterile gloves, sterile gauze, surgical tape, small sterile plaster (if required), stitch
● Gardner RM. Direct blood pressure measurement-dynamic response requirements. Anesthesiology. 2015 Mar;54(3):227-36. PubMed PMID:
● Gershengorn HB, Wunsch H, Scales DC, Zarychanski R, Rubenfeld G, Garland A. Association Between Arterial Catheter Use and Hospital Mortality in Intensive Care Units. JAMA Intern Med.2014 Sep 8. ● McGhee BH, Bridges EJ. Monitoring arterial blood pressure: what you may not know. Crit Care Nurse. 2002 Apr;22(2):60-4, 66-70, 73 passim. Review. PubMed PMID:1191944. ● Scheer B, Perel A, Pfeffer UJ. Clinical review: complications and risk factors of peripheral arterial catheters used for haemodynamic monitoring in anaesthesia and intensive care medicine. Crit Care. 2002 Jun;6(3):199-204. Epub 2002 Apr 18. Review. PubMed PMID: 12133178. ● Ward M, Langton JA. Blood pressure management. Contin Educ Anaesth Crit Pain (2007) 7 (4): 122-126.