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1. Which ofthe following terms describesthe step at which cells become irre- versibly committed to a particular cell fate? Gastrulation Determination Differentiation Specification correct answer Determination 2. Which ofthe followingisthe correct order of developmentalstepsleadingto a specialized cell type? Differentiation, determination, specification Determination, differentiation, specification Determination, specification, differentiation Differentiation, specification, determination Specification, determination, differentiation correct answer Specification, determination, ditterentiation 3. As cells move along the continuum from stem cell to differentiated cell which of the following correctly identifies the properties of a determined cell?
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Gastrulation Determination Differentiation Specification✔✔ correct answer Determination
Differentiation, determination, specification Determination, differentiation, specification Determination, specification, differentiation Differentiation, specification, determination Specification, determination, differentiation✔✔ correct answer Specification, determination, ditterentiation
properties of a determined cell?
Fate is irreversible. Is fully differentiated. It cannot differentiate. Fate is reversible.✔✔ correct answer Fate is irreversible.
will form the mesoderm and endoderm. Killing the P2 cells leads to the disruption of EMS cell differentiation, which of the following best describes the process taking place?
conditional specification of the EMS cell autonomous specification of the P2 cell conditional specification of the P cell autonomous specification of the EMS cell✔✔ correct answer Conditional specification of the EMS cell
of it into the liquid medium covering the epidermal cells in Dish B, you notice that it causes the epidermal cells to round up and thicken. What developmental concept does this example best describe?
Induction of mesenchymal cells by paracrine signaling from epithelial cells Induction of epithelial cells by paracrine signaling from mesenchymal cells Juxtacrine signaling causing induction of the epidermal cells Induction of mesenchymal cells by juxtacrine signaling
Induction of mesenchymal cells by paracrine signaling from the epithelial cells✔✔ correct answer Induction of epithelial cells by paracrine signaling from mesenchymal cells
levels of morphogen after a bead soaked with SHH is transplanted into the rostral side of a limb bud. Which of the following (A-E) best describes the expected pattern of digits?
D A E B C✔✔ correct answer B