Beads Based Cell Isolation
Magnetic beads based cell isolation has become the most widely used and versatile
method for the purification and isolation of key cell populations including lymphocytes,
stem cells, as well as circulating tumor cells. Creative Diagnostics offers custom cell
isolation services to fit your needs in your most critical research requirements.
Magnetic cell sorting can be achieved either by positive or negative selection.
Functional magnetic particles conjugated with antibodies corresponding to particular
cell surface antigen are utilized to capture the interested cells. Then, the magnetic
labeled cells can be separated from unlabeled cells in a magnetic field. Three main
strategies can be applied for magnetic cell labeling: extrinsic labeling, intrinsic labeling,
and cell internalization. With years of experience in immunomagnetic separation, our
scientists are experts in various cell isolation by conventional magnetic-activated cell
sorting (MACS) and microfluidic MACS (Figure 1).
