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BIO 669 Endocrine| study guide verified At Permissive Effects of Hormones - correct answer-A hormone can enable a second hormone to become more functional i.e. GH has a need for thyroid hormone in order to have its full effect Water Soluble Hormones - correct answer-Circulate in free/unbound forms Short-acting response Bind to surface receptors (plasma membrane surface) Unable to freely cross the plasma membrane High molecular weight Lipid Soluble Hormones - correct answer-Steroid and thyroid hormones Act on intracellular receptors that directly activate genes (bind with cytosolic or nuclear receptors of DNA) Rapid and long-lasting effects Bound to carrier proteins in bloodstream Second Messenger Molecules and Water-Soluble Hormones - correct answer-Second messenger molecules amplify the effect of one hormone signal into the cell and has multiple effects on the series of enzymes i.e. Ca++, CAMP, cGMP, IP3 IP3 - correct answer-Leads to the formation of calcium into the cell - and that calcium can frequently act as a second messenger Thyroid Hormone is an example of what type of hormone? - correct answer-A lipid soluble steroid hormone TH is carrier bound which allows for lower fluctuations in TH blood concentrations Adenchypophysis - correct answer-The anterior pituitary portal system of linear capillaries