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Biochem Study Guide Review Notes

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Biochem Study Guide Review Notes
1.pH less than 7.35: Acidosis
2.pH greater than 7.45: Alkalosis
3.If Bicarb & pH arrows are in the same
direction If Opposite: Metabolic
Respiratory
4.As the pH goes down...so
does Except for: my patient
Potassium
5. Low pH=
High pH=: everything is low, K is high (lethargy 1+ reflex Dec HR)
everything is high, K is low (Irritable, 3+ reflex, Inc HR, Borrigmi-inc
bowel sounds)
6.Reflexes: 0-1 is
hypo 2 normal
3-4 high
7. Seizures=
Respiratory distress=: alkalosis-need suctioning @
bedside acidosis- need ambubag @ bedside
8.MAC KUSSMAL: kussmal respirations for metabolic acidosis
9. Causes of respiratory
If not respiratory, its:
Lungs Metabolic
10.Cause of alkalosis/acidosis: prolonged suction or vomiting (Metabolic
alkalo- sis)
overventilating-
alkalosis
underventilating-
acidosis
11.When you dont know what it is (ex: werid condition) or everything that
isnt lung, pick: metabolic acidosis
12.Always pay more attention to the modifying phrase than to the
original noun.:
13.High pressure ventilator alarms are triggered
by Look for
What to do: Inc resistance to air flow
Look for obstructions (kink, condensed H20, empty it, mucus plug)
14.Steps to take when adressing high pressure alarms: 1.)
unkink 2.) empty
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Biochem Study Guide Review Notes

  1. pH less than 7.35: Acidosis
  2. pH greater than 7.45: Alkalosis
  3. If Bicarb & pH arrows are in the same direction If Opposite: Metabolic Respiratory
  4. As the pH goes down...so does Except for: my patient Potassium 5. Low pH= High pH=: everything is low, K is high (lethargy 1+ reflex Dec HR) everything is high, K is low (Irritable, 3+ reflex, Inc HR, Borrigmi-inc bowel sounds)
  5. Reflexes: 0-1 is hypo 2 normal 3-4 high 7. Seizures= Respiratory distress=: alkalosis-need suctioning @ bedside acidosis- need ambubag @ bedside
  6. MAC KUSSMAL: kussmal respirations for metabolic acidosis 9. Causes of respiratory If not respiratory, its: Lungs Metabolic
  7. Cause of alkalosis/acidosis: prolonged suction or vomiting (Metabolic alkalo- sis) overventilating- alkalosis underventilating- acidosis
  8. When you dont know what it is (ex: werid condition) or everything that isnt lung, pick: metabolic acidosis **12. Always pay more attention to the modifying phrase than to the original noun.:
  9. High pressure ventilator alarms are triggered by Look for What to do:** Inc resistance to air flow Look for obstructions (kink, condensed H20, empty it, mucus plug)
  10. Steps to take when adressing high pressure alarms: 1.) unkink 2.) empty

3.) turn pt or cough 4.) suction-IF NEEDED

15. Low pressure alarms are triggered by Look for

interest of s/o THE NATURE OF THE ACT IS HARMFUL

  1. if the act being asked to do isnt harmful, its: dependency vs co- dependency
  2. To treat manipulation, you have to: set limits & enforce
  1. Wernicke & Korsakoff: NCLEX bundles together Wernicke-encephalopathy Korsakoff-psychosis 31. Psycosis is induced by... What happens to the pt? S&S: They beleive what: Vitamin B1 thiamine deficiency They loose touch with reality amnesia, confabulation (making up stories) Their own made up stories
  2. How do you treat these pts: redirect them to do something they CAN do Ex: watching tv
  3. Characteristics of the syndrome: 1.) Preventable-take B1 2.) Arrestable- Take B 3.) Irreversable it will kill brain cells 34. ALWAYS ANSWER NCLEX Q W/ Majority answer:
  4. Abtabuse vs Revia: alcohol deterrent antidote 36. Abtabuse Onset, duration contraindications: 2 wks, 2 wks, pt must take for 2 wk or stop for 2 wk all forms of alc (mouth wash, aftershave, vanilla, perfume) *CAN have red wine vinegrette
  5. First question you ask with overdose/withdrawl: is it an upper or downer
  6. Upper: Caffiene, cocaine, LSD/PCP, Methanphetamines, Adderall
  7. Downer: anything that is not an upper
  8. S&S of uppers: Things go UP!
  • Euphoria, seizures, restlessness, irritability, hyperreflexia (3+, 4+), tachycardia, increased bowels (borborygmi), diarrhea
  1. S&S of downers: Things go DOWN!
  • Lethargic, respiratory depression/arrest, constipated, etc.
  1. Nursing priority of uppers vs downers: Upper: suctioning d/t seizures Downer: intubation/vent d/t resp distress *Dont get tricked thinking all drug OD cause resp distress 43. Overdose on an upper vs

44. Overdose on a downer vs Withdrawl on a downer: too little too much 45. Examples: Pt OD on cocaine Upper or downer? Overdose or withdrawl? S&S:: Upper OD Inc temp, 4+ reflex, borbygmi Have suction

  1. Examples: Pt withdrawing on cocaine: Upper Withdrawl Resp depression (under 12), give narcan
  2. Aversion therapy: makes pt give up undesirable habit by causing them to associate it w/ unpleasant effect *Works better in theory
  3. Drug abuse in newborn: always assume intoxication, not withdrawal at birth *You can assume withdrawal after 24hrs
  4. Alcohol withdrawl syndrome vs Delirium tremors: NOT the same Every alcoholic goes through withdrawl 24 hrs after stopping drinking. Only minority get delirum tremens (72 hrs after drinking)
  5. Alcohol withdrawl syndrome always precedes: delirium tremens *(However delirium tremens doesnt always follow withdrawl)
  6. Alcohol withdrawl occurs & is: 24 hrs after drinking not life threatening to self or others
  7. Delirium tremens occurs & is: 72 hrs after drinking Life threatening to self or others
  8. Care plan for alcohol withdrawal: regular diet Semi private room anywhere on unit pt up ad lib (free to move) no restraints!!!
  9. Care plan for Delirium tremens: NPO or clear liquid Private room by nurse station Restricted bed rest Vest or 2pt restraint- NO WRIST RESTRAINTS!!

55. 2pt lock letter restraints What meds should you give?: restraints in upper & contralateral lower extremities. Release & secure upper arm 1st, then release & secure foot.

  1. Toxic effects of aminoglycosides?: -mycin = Mice Mice = Ears --> Ototoxicity

Ears = Kidney-shaped --> Nephrotoxicity (monitor creat) Draw an 8 in the ear --> Affects cranial nerve VIII Administer them q8 hours

67. Best indicator of kindey function What better than serum creatnine: creatinine 24 hr creatinine clearence

  1. Amino-glycosides are given: IM or IV-not PO Unless: hepatic encephalopathy (inc ammonia levels) Pre op bowel surgery (sterilizes bowel)
  2. #1 action of oral mycin: sterilize bowel Who can sterilize my bowel ( NEO KAN!) neomycin & kanamycin *E-coli= 1 ammonia producer toxic levels can lead to encaphlopthy mycin kills e coli 70. Troug h vs Peak: drug is at lowest concentration in blood highest concentration in blood 71. "TAP" levels - trough, administer, peak trough should be taken peak is after Both are drawn d/t: trough b4 drug administration peak after administration both are drawn d/t narrow theraputic window
  3. What does a narrow therapeutic index mean: small difference in what works vs kills
  4. When to draw peak & trough: The med doesnt matter! The Route does!
  5. Trough is always drawn: 30 min b4 next dose 75. Peak s Sub L IV IM Sub Q PO: 5-10 min after drug distributed 15-30 min after drug distributed

Dependent on insulin Not tested

  1. What is one type of med that needs a peak and trough drawn: amino- glyco- sides "mycin" d/t narrow therapeutic range 77. Calcium channel blockers are like What do they do They are: Valium for the heart relax & slow HR Ino, chrono, dromotropic
  2. **+Initropy chronotropy dromotropy
  • Initropy chronotropy dromotropy:** Stimulant Depressant
  1. What happens with + chronotropy: Inc rate of impulse formation SA node inc HR
  2. What happens with + inotropy: inc cardiac force Ventricles empty more completely
  3. What happens with + dromotropy: Inc conduction velocity
  4. What happens with - inotropy: weaken/decrease myocardial contraction
  5. What happens with - chronotropy: dec rate of impulse formation Sa node & dec HR
  6. CCB treats: A, AA, AAA Antihypertensive, Antianginal (dec O2 demand), antiarrythmia THEY WILL NOT TREAT VENTRICULAR ONLY ATRIAL
  • Exception to SVT
  1. SE of CCB: headache and hypotension *Headache is great to choose on SAP
  2. CCB suffix and meds: Dipine not Pine & verampimil, cardizem (diltiazem) IV drip
  3. With CCB what do you always assess: HR & BP 60/90 rule
  4. Normal sinus rythm: 60-100 bpm
  5. V fib: completely erratic rhythm with no identifiable waves; fatal 90. V-tach:
  6. IF a question mentions QRS depolarization it is= P wave is=: Ventricular Atrial 92. The 6 arrytmias on

NCLEX: Lack of QRS: P (atrial waves) in saw tooth formation: Chaotic P waves:

  1. Tx of v-fib & asystole: De fib for V fib Epi & atropine for asystole

101. tx for atrial arrytmia tx for ventricular arrytmia: adena, beta, calcium, dig amiodarone

  1. What kind of pressure do we want for chest tubes: negative to bring together & re-establish negative pressure in the pleural space. *Makes things stick. so the lung expands when the chest wall does. 103. Pneumoth orax Hemothorax Hemopneumothorax: chest tube removes air (bubbling is expected) Chest tube removes blood Chest tube removes air & blood 104. PAY ATTENTION TO WHAT TYPE OF THORAX WHEN ANSWERING QUES- TIONS:
  2. Also pay attention to the location the chest tube is placed A vs B: A= Air/Apical or on top B=Blood or base
  3. If a pt presents with unilateral hemothorax what would be placed for pnemo vs hemo: pnemo-apical Hemo-basilar
  4. Bilateral pneumothorax needs a: apical on the right & left Air tube=apical 108. Always assume trauma & surgery is unilateral unless specified:
  5. Pneumonectomy means the pt has: no lung or pleural space=NO chest tube 110. Closed chest drainage types If one is knocked over what should you do: jackson pratt, hemovac, emisson ask pt to take a deep breath & set back up
  6. If the water seal breaks what should you do and how much time do you have: 1.) CLAMP 2.) Cut 3.) submerge in sterile water-MOST IMPORTANT/priority 4.) Unclamp You have under 15 seconds *Difference between first step & priority 112. IN A BEST QUESTION, YOU ONLY GET TO DO ONE OF THE OPTIONS:
  7. What should you do if a chest tube gets pulled out: 1.) take a
  1. If the chest tube is bubbling ask 2 questions: Where its bubbling & When its bubbling 115. If Water seal chamber If Suction control chamber: Intermittent is good (document Continuous is bad (break/leak) find it & tape it Intermittent is bad (suction isnt high enough) Continuous is good (document)
  2. Chest tube is high risk of what vs thoracentesis: infection d/t longer time of stay 117. Rules for clamping tubes dont clamp for more than Use what kind of clamp What to do when the water seal breaks: 15 sec unless you have dr order rubber tooth double clamp No more than 15 sec to clamp, cut, submerge, unclamp
  3. Congenital heart defects are either: trouble or no trouble
  4. TRouBle: TRouBle is how to determine if its trouble *Shunts blood R to L Blue meaning cyanotic All trouble starts w/ tetrology of fallout
  5. All congenital heart defects start with: T
  6. All children with a congenital heart defect have: a murmur echo needs to be done to find cause
  7. 4 defects of tetralogy of fallout "prove": Pulmonary artery stenosis RVH (right ventricular hypertrophy) Overriding aorta VSD (Ventricular septal defect) *Just spot these on SAP question 123. Contact precuations Causes: PPE: Room: Can they share a room:: Anything enteric (GI or fecal/oral) Ex: c-diff, Hep A, E coli, chollera, RSV (also droplet) Staph, herpes Gown & gloves

Can be in same room based on cultures if no symptoms Disposable equipment *No mask