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- Hormones (A) Act as coenzyme (B) Act as enzyme (C) Influence synthesis of enzymes (D) Belong to B-complex group
- Hormone that binds to intracellular receptor is (A) Adrenocorticotropic hormone (B) Thyroxine (C) Follicle stimulating hormone (D) Glucagon
- Hormone that bind to cell surface receptor and require the second messenger camp is (A) Antidiuretic hormone (B) Cholecystokinin
(C) Calcitriol (D) Gastrin
- A hormone secreted from anterior pituitary is (A) Growth hormone (B) Vasopressin (C) Oxytocin (D) Epinephrine
- A hormone secreted from posterior pituitary is (A) Vasopressin (B) Thyrotropic hormone (C) Prolactin (D) Adrenocorticotropic hormone
(A) Thyroxine (B) Growth hormone (C) Insulin (D) Glucagon
- Growth hormone is released by (A) Somatostatin (B) Growth hormone releasing hormone (C) Prolactin release inhibiting hormone (D) Luteinizing releasing hormone
- The number of amino acids in prolactin is (A) 134 (B) 146 (C) 172 (D) 199
- Adrenocorticotropic hormone (ACTH) is a single polypeptide containing (A) 25 amino acid (B) 39 amino acid (C) 49 amino acid (D) 52 amino acid 208 MCQs IN BIOCHEMISTRY
- Biological activity of ACTH requires (A) 10-N-terminal amino acid (B) 24-N-terminal amino acid (C) 24-C-terminal amino acid (D) 15-C-terminal amino acid
- ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine
(B) Cyclic GMP (C) Calcium (D) Magnesium
- The circulating concentration of ACTH in plasma is (A) 0.05 m /100 ml (B) 0.1–2.0 m /100 ml (C) 2.5–3.5 m /100 ml (D) 3.0–5.0 m /100 ml
- Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6- biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase
(D) Stimulation of synthesis of eltroxykinase
- The predominant glucocorticoid is (A) Cortisol (B) Aldosterone (C) Dehydroephiandrosterone (D) Androstenedione
- A specific cortisol binding protein, transcortin is a (A) Albumin (B) 1-Globulin (C) 2-Globulin (D) -Globulin
- Cortisol is synthesized in (A) Zona fasiculata (B) Zona glomerulosa
- In adrenal gland the cholesterol is stored (A) Mostly in the free form (B) Mostly in esterified form (C) Large amount of free form and less amount of esterified form (D) Equal amounts of free and esterified form
- Aldosterone synthesis occurs in (A) Zona reticularis (B) Zona fasciculata (C) Zona glomerulosa (D) Chromaffian cells
- In the biosynthesis of cortiol, the sequence of enzymes involved is
(A) Hydroxylase–dehydrogenase + isomerase – hydroxylase (B) Dehydrogenase–hydroxylase– isomerase (C) Hydroxylase–lyase–dehydrogenase isomerase (D) Isomerase–lyase–hydroxylase– dehydrogenase
- The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency
- The most important effect of aldosterone is to (A) Increase the rate of tubular reabsorption of sodium (B) Decrease the rate of tubular reabsorption of potassium (C) Decrease the reabsorption of chloride (D) Decrease the renal reabsorption of sodium
- One of the potent stimulators of aldosterone secretion is (A) Increased sodium concentration (B) Decreased potassium concentration (C) Increased potassium concentration (D) Increased ECF volume
- In the rennin-angiotensin system the primary hormone is (A) Angiotensinogen (B) Angiotensin I (C) Angiotensin II (D) Angiotensin III
- Aldosterone release is stimulated by (A) 2-Globulin (B) Renin (C) Angiotensin II (D) Growth hormone
- In the synthesis of Angiotensin I, rennin acts on Angiotensinogen and cleaves the
(B) p-Hydroxy derivatives of phenylacetate (C) p-Hydroxy derivatives of phenylpyruvate (D) p-Hydroxy derivatives of phenyllactate
- The sequential steps in the conversion of tyrosine to epinephrine are (A) Ring hydroxylation- decarboxylation-side chain hydroxylation-N-methylation (B) Side chain hydroxylation- decarboxylation-ring hydroxylation N-methylation (C) Decarboxylation-ring hydroxylation- side chain hydroxylation-N-methylation
(D) N-methylation-decarboxylation-ring and side chain hydroxylation
- The hormone required for uterine muscle contraction for child birth is (A) Progesterone (B) Estrogen (C) Oxytocin (D) Vasopressin
- The number of amino acids in the hormone oxytocin is (A) 7 (B) 9 (C) 14 (D) 18
(C) 27
(D) 36
43. ADH
(A) Reabsorbs water from renal tubules (B) Excretes water from renal tubules (C) Excretes hypotonic urine (D) Causes low specific gravity of urine 210 MCQs IN BIOCHEMISTRY
- Increased reabsorption of water from the kidney is the major consequence of the secretion of the hormone? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone
- An increase in the osmolality of extracellular compartment will (A) Inhibit ADH secretion (B) Stimulate ADH secretion (C) Cause no change in ADH secretion (D) Stimulate the volume and osmoreceptor and inhibit ADH secretion
- For Catecholamine biosynthesis the rate limiting enzyme is (A) DOPA decarboxylase (B) DOPAMINE -hydroxylase (C) Tyrosine hydroxylase (D) Phenylalanine hydroxylase
