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Yahi Ahmed Tousfik “Te Clete ooine Chose coats in Bah pe Cel fr Cig Mitochondria For-( Krebs ggele) Vet.KsTu2026 if © OKilotive Deomborylabion oF Ppuvate To Acetyl CoA fey @ | 9 te dro xe u CH, ~ C - COOH ; CH, - C ~SCoA Pyruvate TPP, Lxgy FAD, 2 Acetyl CoA nap* —COASH NADH+H* {Bean ‘ee, xe. (FAD \ cle | “acetyl coA NADH+H* centames ate: © Thiamin PyroPhesPhat (TPP) _LiPoic_ Acid ® Coemyne A__(CoAsit) @ Flavin adenine dieuclectide (FAO) ©) Nicotinamide adenine diqucletide (VADs) 6 ktp) 2 (POH)? Caleium | ——_ Ineulin Caléium) Paw ors oN Acetyl CoA, 77. Pyruvate Acetyl CoA», 1 1 oH / \ NAD? (WADIOH ‘ . 7 {seo — coasH 7 1 SNe ad ap ~~ ate. 3 fom Kebeglutotate = Leeghise Mba Succing| ~Comrayme A NADY —> NADH Succinate Sucsiic. enase FAD —> FADH. 2} Fumatate Cowes bo Malate By “Fumatase’ Enee —> Energy Production of» one Acetil cod —» 12 ATP. Glucose . ae aay aan . [3éor3e Ate] rate ofp C0 whete. ma ae a ms DC it tes. Pradned an $. ae L So Fa the Ll alin f All ArPS Pradurdy ute ile 3 AtP_ Soe cone chose Malecle aridatien 4 eng f= Gat " 2) E i i ATP. “ oA (eatlicen 3) Acetyl coA Produces 12 ATP in Krebs gees So for the 2 Acetyl coh total ef 24 ATP. Lt) So For the botal addition of All ATPs Produced, we will a 36 o 3p ATP Yor one Glucose Molecule ofidation. PabokSnn Atlod | Ge AT Gar | a 36 1 38 liar deh hea suse J —> Functions (signiPtcance) of Ted: TEA is amthibolic 3 Mas Catabolic 2 Anabalic Sunctians. —»iCatabelic Functions L Oridaion of Cay dle ils Pobins 2} Anabolic Functions 2 | L, Formation of» a) ARBNAeiNS | Gives Transamination. — Olsloacetate Gives AsPaitate Gy Trensamination. hGuas | — akilaghtinle Goes Ghose By 6 . c) ery a d) Katy Acid. & chelesterl wen Cok Gives Fatty acid chelslol __CSyethenaed in ysl). £) CBE Pre in Te. 4 in Fellowi katie tions ry Pytwvmte + Cor Gives Onloncetste , & Olsleacebate Gives Cluose By Gluconeageneis 2) Acely| coh + Con Gives Malogl cok & Malensl oA Gives Fatty Acts Giver i i sive i Kan intetmediate in cittic acid. cyl). 5) Formation of Cb of Patine Ciote: co of Parnes is Tom Cotton diotidle pshile C4 2. C5 of Patines is From Glycine) 6) Qypthesis FP Hacos Hos _buiter (Maintains Notmal PH Pale 7.4 t 0-03). —» in Vilto inhibition of TEA cyle: ) Flouroocetate — inhibits “Aomitose” Enzyme L 2) Aisenate inhibits “or Keleglutarcte deby droge nase” Enayme ‘ 1,3) Malonic Acid inhibils “Succinate dehydrogenase” Enayme — Key Enegmes oS Krebs Cycle: Le(O Cittate Synthase. Le a. Keloghitarete debydieg enase. Made By : Yahi Khmed Toslik 20 Vet.KsTu_20 
