Biology Modules 1-7 Quizzes: Transcription, mRNA Processing, Mitosis & Cancer, Translation, Quizzes of Biology

Practice quizzes covering key concepts in biology, including transcription, mrna processing, mitosis, cancer, and translation. It includes multiple-choice questions and matching exercises designed to test understanding of these fundamental biological processes. The quizzes are suitable for students studying introductory biology at the university or high school level.

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Biology Modules 1-7 Quizzes Practice
Quizzes
Transcription and mRNA Processing Practice Quiz
1. Transcription , while translation .
a. Requires ribosomes; requires tRNAs and RNA polymerase
b. Occurs in cytosol of eukaryotic cells; occurs in the nucleus of eukaryotic cells
c. Is the synthesis or RNA; is the synthesis of protein
d. Requires tRNA; requires rRNA
2. Put the rolling steps of transcription in the correct order
i. RNA polymerase binds the promoter
ii. RNA polymerase reaches the terminator
iii. Transcription bubble formed
iv. RNA polymerase makes RNA, beginning at the start point
a. 1-3-4-2
b. 1-4-3-2
c. 4-1-3-2
d. 3-1-4-2
3. Which of the following is accurate for BOTH DNA polymerase and RNA polymerase
a. They both make RNA
b. They both unwind the double helix
c. They both work in the nucleus and build molecules in the 5’ to 3’ direction
d. They both need primers or some other existing strand with a 3’-OH to function
e. They both make DNA
4. Match the RNA with its description/function
a. mRNA -- carries a genetic message from the DNA to ribosomes
b. rRNA -- along with proteins, is part of the structure of ribosomal subunits
c. tRNA -- transfers amino acids from a cytoplasmic pool of amino acids to
a growing polypeptide in a ribosome
d. snRNA -- matches specific sequences in introns; required for splicing
5. The figure below represents a segment of a gene encoding for the oxytocin protein
from sheep. The BOTTOM STRAND IS THE TEMPLATE STRAND
5’...AGCGCGTCTGC...3’
3’...TCGCGCAGACG...5’
a. 5’UCGCGCAGACG3’
b. 3’TCGCGCAGACG 5’
c. 3’AGCGCGUCUGC5’
d. 3’UCGCGCAGACG5’
e. 5’AGCGCGUCUGC3’
6. As described in lecture, what are the functions of the polyA tail? Select all
correct choices.
a. Intron removal
b. Exit or RNA from the nucleus
1
pf3
pf4
pf5
pf8
pf9
pfa
pfd
pfe
pff

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Biology Modules 1-7 Quizzes Practice

Quizzes

Transcription and mRNA Processing Practice Quiz

  1. Transcription , while translation. a. Requires ribosomes; requires tRNAs and RNA polymerase b. Occurs in cytosol of eukaryotic cells; occurs in the nucleus of eukaryotic cells c. Is the synthesis or RNA; is the synthesis of protein d. Requires tRNA; requires rRNA
  2. Put the rolling steps of transcription in the correct order i. RNA polymerase binds the promoter ii. RNA polymerase reaches the terminator iii. Transcription bubble formed iv. RNA polymerase makes RNA, beginning at the start point a. 1-3-4- 2 b. 1-4-3- 2 c. 4-1-3- 2 d. 3-1-4- 2
  3. Which of the following is accurate for BOTH DNA polymerase and RNA polymerase a. They both make RNA b. They both unwind the double helix c. They both work in the nucleus and build molecules in the 5’ to 3’ direction d. They both need primers or some other existing strand with a 3’-OH to function e. They both make DNA
  4. Match the RNA with its description/function a. mRNA -- carries a genetic message from the DNA to ribosomes b. rRNA -- along with proteins, is part of the structure of ribosomal subunits c. tRNA -- transfers amino acids from a cytoplasmic pool of amino acids to a growing polypeptide in a ribosome d. snRNA -- matches specific sequences in introns; required for splicing
  5. The figure below represents a segment of a gene encoding for the oxytocin protein from sheep. The BOTTOM STRAND IS THE TEMPLATE STRAND 5’...AGCGCGTCTGC...3’ 3’...TCGCGCAGACG...5’ a. 5’UCGCGCAGACG3’ b. 3’TCGCGCAGACG 5’ c. 3’AGCGCGUCUGC5’ d. 3’UCGCGCAGACG5’ e. 5’AGCGCGUCUGC3’
  6. As described in lecture, what are the functions of the polyA tail? Select all correct choices. a. Intron removal b. Exit or RNA from the nucleus

c. Correct positioning of mRNA on ribosomes d. Protection; makes the RNA molecule more stable

  1. What is a codon? a. A thin latex rubber or natural membrane sheath often used as a barrier method of birth control b. A three-nucleotide sequence of DNA or mRNA that specifies which amino acid gets put in a protein c. A nucleotide triplet in the bottom loop of a tRNA molecule d. A site where RNA polymerase binds to a gene and terminates transcription e. An amphipathic amino acid
  2. A tRNA has an anticodon 3’AGC 5’. When the tRNA is charged, which amino acid will be bound? a. Phe b. Ala c. It’s impossible to determine d. Arg e. Ser

Mitosis & Cancer Practice Quiz

  1. A metaphase chromosome (select all correct choices) a. Contains identical DNA molecules that will be separated from each other during anaphase of mitosis b. Is composed of a single DNA double helix in a highly condensed form c. Is the loosest level of DNA packaging d. Is found in the S phase of the cell cycle e. Is composed of two sister chromatids attached at the centromere f. Is composed of two sister chromatids attached at a centrosome
  2. What is a karyotype? a. in a duplicated chromosome, the region on each sister chromatid where they are most closely attached to each other; this close attachment causes a constriction in the condensed chromosome b. a structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle c. a display of the chromosome pairs of a cell arranged by size and shape d. a hollow rod composed of tubulin proteins that makes up part of the cytoskeleton in eukaryotic cells e. a structure in the cytoplasm that serves as a microtubule organizing center and is important in cell division

c. Anaphase -- kinetochore microtubules shorten, nonkinetochore microtubules lengthen, sister chromatids pulled apart, cell elongates d. Telophase/Cytokinesis -- chromosomes decondense, nuclear envelope reforms, cleavage furrow forms, parent cell splits into two daughter cells

  1. What is the correct order of the cell cycle/mitosis based on the diagram below? a. E, A, C, D, B b. A, B, C, D, E c. B, E, A, D, C d. A, C, E, B, D e. C, D, A, E, B
  2. Cohesins degrade at which stage of mitosis? a. Anaphase b. Telophase c. Cytokinesis d. Metaphase
  3. Cell cycle control in yeast and animals utilizes a signal transduction pathway. Which of the following is the correct order of stages in a signal transduction pathway? a. Reception, Response, Transduction b. Transcription, Translation, Replication c. Transduction, Reception, Response d. Response, Transduction, Reception e. Reception, Transduction, Response
  4. A cell cycle checkpoint is a control point where progress through the cell cycle is stopped, at least temporarily, so the cell can monitor itself to make sure that all cell processes are complete and accurate as the cell cycle proceeds. At which checkpoint does the cell check to make sure that all kinetochore microtubules are correctly attached? a. G b. G1, G2 & M c. G d. M e. G1 & G
  5. Match each term with its correct definition/description a. Anchorage dependence -- a cell must be attached to its appropriate substratum in order to initiate cell division b. Density-dependent inhibition -- the phenomenon observed in normal animal cells that causes them to stop dividing when they become too crowded c. Growth factor -- a protein that must be present in the extracellular environment for normal cells to stop dividing
  6. Match each term with its correct definition/description a. Oncogene -- mutated gene, can lead to cancer b. Proto-oncogene -- normal versions of oncogene, which codes for proteins that

stimulate normal cell growth and division c. Telomerase -- an enzyme that catalyzes the lengthening of telomeres in some eukaryotic and cancer cells d. Tumor suppressor -- protein that helps prevent uncontrolled cell growth

  1. In many cancers are converted to , and are mutated. a. oncogenes; proto-oncogenes; tumor suppressor genes b. proto-oncogenes; tumor suppressor genes; oncogenes c. proto-suppressor genes; tumor suppressor genes; telomerase d. proto-oncogenes; oncogenes; tumor suppressor genes e. oncogenes; tumor suppressor genes; proto-oncogenes
  2. Match each type of cell division with its correct description. a. Mitosis -- division of somatic cells b. Meiosis -- production of gametes c. Binary Fission -- division of prokaryotic cells
  3. If a tumor suppressor gene is mutated a. tumor formation will be suppressed b. that person is less likely to get cancer c. cells can pass through cell cycle checkpoints, even if they are damaged d. there is 100% chance the person with the mutation will get cancer

Translation Practice Quiz

  1. Which of the following statements about tRNA are accurate? Select all correct choices a. each tRNA is a single-strand RNA that folds into a three-dimensional shape that looks somewhat like an "L" b. tRNAs are made by transcription c. tRNAs have anticodons d. tRNAs have codons e. tRNAs are a permanent part of ribosome structure f. tRNAs can have an amino acid attached
  2. A tRNA has an anticodon 3'CGA 5'. During translation, to which codon will that anticodon bind? a. 3' GCU 5' b. 5' GCU 3' c. 5' CGA 3' d. 5' GCT 3' e. 3' CGA 5'
  3. A tRNA has an anticodon 3'CGA 5'. When the tRNA is charged, which amino acid will be bound? a. Impossible to determine

three nucleotides? a. the tRNA that was in the A site moves into the E site b. the tRNA that was in the P site moves into the A site c. the tRNA that was in the E site moves into the P site d. the tRNA that was in the P site moves into the E site e. the tRNA that was in the E site moves into the A site

  1. How is translation terminated? a. the ribosome becomes weary and falls apart b. the ribosome reaches the telomeres c. the cell runs out of ribosomes d. a stop codon enters the A site of the ribosome e. the ribosome falls off the 3' end of the mRNA
  2. Shown below is a segment of the sheep oxytocin gene. Which of the following represents the first five amino acids in the polypeptide that is encoded by this gene? The BOTTOM strand is the TEMPLATE strand. 5’...AGCGCGTCTGCACCATGGCAGGTTCCAGCCTCGCTGCTGCCTGCTG G...3’ 3’...TCGCGCAGACGTGGTACCGTCCAAGGTCGGACGCACACGGACGAC C...5’ a. Met – Ala – Gly – Ser - Ser b. Met – Val – Gln – Thr – Arg c. impossible to determine because the code is redundant d. Ser – Arg – Arg – Arg - Gly e. Thr – Ala – Ser – Ala – Pro

Lecture Quiz 1

  1. Two adjacent carbon atoms share a pair of electrons. This bond a. is a polar covalent bond b. is a hydrogen bond c. is a hydrophilic bond d. involves unequal sharing of electrons e. is a nonpolar covalent bond
  2. The structure shown here is sucrose. Sucrose is a and is formed by connecting two. a. disaccharide....polysaccharides b. dipeptide....amino acids c. disaccharide .... monosaccharides d. oligosaccharide....disaccharides e. disaccharide....amino acids
  3. How are starch and glycogen similar to each other?

a. both are energy storage polysaccharides b. both are produced by plants c. both are produced by animals d. neither can be digested by humans e. both are disaccharides

  1. A hydrophilic substance while a hydrophobic substance a. usually contains only C-C and C-H bonds....usually has O-H, N-H, or S-H as part of its structure b. repels water. .has affinity for water c. is a solvent....is a solution d. forms hydrogen bonds with water.. is water-fearing e. is water-fearing. is water-loving
  2. Match each description/definition with the appropriate level of protein structure. a. overall shape of protein resulting from interactions between R groups i. Tertiary b. segments of the polypeptide chain are repeatedly coiled or folded due to hydrogen bonding between repeated sequences in the polypeptide chain i. Secondary c. the amino acid sequence of a protein, from beginning to end i. Primary d. assembly of multiple polypeptides into a functional protein i. Quaternary
  3. Changing a single amino acid in a polypeptide chain. Select all correct choices a. always changes the quaternary structure of a protein b. sometimes changes the secondary structure of a protein c. always changes the primary structure of a protein d. always changes the secondary structure of a protein e. always causes disease f. always changes the function of the protein g. sometimes changes the quaternary structure of a protein h. sometimes changes the tertiary structure of a protein i. never changes the primary structure j. sometimes leads to diseases/disorders k. always changes the tertiary structure of a protein l. sometimes alters the function of a protein
  4. In the tertiary structure of a normal, soluble, cellular protein, where would you expect to find the amino acid serine? The structure of serine is shown below. a. any of these answers are equally likely b. on the interior of the protein due to ionic bonding c. randomly distributed throughout the protein d. on the exterior of the protein because it can form hydrogen bonds with

c. They contain only saturated fatty acids d. they are composed of one glycerol, two fatty acids and a phosphate containing head group e. they are composed of one glycerol and three fatty acids f. they are an essential component of cell membranes g. they are energy-storage molecules

  1. Rank the three types of fats in order from LEAST healthy to MOST healthy. (See TED TALK: What is Fat?) a. Trans, cis, saturated b. Cis, trans, saturated c. Trans, saturated, cis d. Cis, saturated, trans e. Saturated, cis, trans
  2. The picture below is creeping wintergreen. Which of the following changes would you expect to see in the cells of this plant as the season changes from fall to winter (i.e. as the temperature decreases)? a. a decrease in the amount of sterols in its membranes b. an increase in the amount of saturated fatty acids in its membrane phospholipids c. an increase in the amount of active desaturase d. more proteins in its membranes e. an increase in the amount of unsaturated fatty acids in its membrane phospholipids f. an increase in the amount of sterols in its membranes g. an increase in the amount of short fatty acids in its membrane phospholipids
  3. Which of the following would have the most trouble crossing a biological membrane composed only of a phospholipid bilayer? a. O2 (oxygen) b. H20 (water) c. A small hydrophobic molecules (like estrogen) d. CO2 (carbon dioxide) e. Na+ (sodium ion)
  4. How is facilitated diffusion similar to active transport? a. both processes are used to transport water across biological membranes b. both require aquaporins c. both processes are types of passive transport d. in both processes, molecules move against their concentration gradient e. both processes require ATP f. both processes require transmembrane proteins
  5. The figure here shows a kidney (animal) cell. It has been placed into an unknown solution. Which of the following is/are TRUE regarding this figure? Water moves rapidly

across membranes of this type of kidney cell. a. the cytosol of the cell is hypotonic to the solution b. the solution and the cell cytosol are both hypertonic c. the cytosol of the cell is hypertonic to the solution d. the cytosol of the cell is isotonic to the solution e. water is moving across the cell membrane via carrier proteins f. water is moving across the cell membrane both by simple diffusion and by facilitated diffusion via aquaporins

  1. An individual is not able to remove LDL from her bloodstream and has extremely high blood cholesterol. Which of the following is a potential explanation for her high cholesterol? Select all correct choices a. she has misfolded LDL receptors b. she has too many LDL receptor in her membranes c. she has a defect in pinocytosis d. she is missing the LDL active transport pump e. she has a defect in receptor-mediated endocytosis f. she has a defect in the apolipoproteins in her LDL complexes g. she cannot carry out phagocytosis h. she has a defect in exocytosis

Lecture Quiz 2

  1. Amoxicillin is a broad-spectrum antibiotic that interferes with the synthesis of peptidoglycan cell walls. You take amoxicillin to treat strep throat. Amoxicillin kills bacterial cells and not yours because a. your cells do not have a cell wall b. antibiotics like amoxicillin are super-specific and only kill disease- causing bacteria c. your cells have a cell wall, but its not composed of peptidoglycan d. your cells have organelles that protect them from the drug e. your cells are prokaryotic, while the bacterial cells are eukaryotic
  2. Using model organisms and human studies, what have we learned about the role of bacteria in our gut? a. that our gut microbiome impacts our mental health b. that they have no impact on our development or function c. that they can be impacted by antibiotic use and what we eat d. that obesity and leanness are correlated with different microbiomes
  3. The gut brain axis allows for bi-directional communication between gut microbes and the brain. Which of the following is NOT a route by which bacterial residents of the intestines may influence neurons and the brain through several routes. a. short chain fatty acids secreted by microbes travel from the gut to the brain via blood vessels b. microbes directly infiltrate the bloodstream and are then taken into brain

k. Peroxisomes - has various metabolic functions; produces hydrogen peroxide as a by-product, then converts it to water and oxygen

  1. You decide you want to study the function of the nuclear lamina. Based on what you learned in lecture, which of the following would be the LEAST likely to be a useful model organism? a. Drosophila melanogaster (fruit fly) b. Escherichia coli (a bacterium) c. Danio rerio (zebrafish) d. Saccharomyces cerevisiae (yeast, a fungus) e. Dictyostelium discoideum (a protist) f. Arabidopsis thaliana (plant)
  2. You discover a mutant pufferfish that makes defective lamin proteins. Which of the following would you likely observe? Select all correct choices a. delayed aging processes b. defective ribosomes c. abnormally-shaped nuclei d. normal nuclei e. abnormal cell wall structure f. disorganized chromatin (DNA)
  3. From the choices below, select all that are NOT correct about the nuclear envelope. a. it directly connects to the membranes of the mitochondria b. it surrounds the nucleoid region in prokaryotic cells c. it is found in both prokaryotic and eukaryotic cells d. it contains pores e. it is a membrane consisting of one phospholipid bilayer f. it encloses the nucleus, separating it from the cytoplasm
  4. You genetically engineer a line of fruit flies to produce DNA polymerase with no nuclear localization signal (NLS). Which of the following is the likely result? a. the DNA polymerase will go through the endomembrane system and be released from the cell by exocytosis b. the cells of the fruit fly will not replicate their DNA c. nothing, DNA polymerase is made in the nucleus d. the lamin proteins will go into the nucleus but will not fold normally e. the DNA polymerase will not go into the nucleus, but the fruit flies and their nuclear function will be normal
  5. Peels of citrus fruits, such as oranges and lemons, have large oil pockets. The cells that produce the oils are likely abundant with which organelle? a. smooth ER b. plants don't have organelles c. nuclei d. lysosomes

e. chloroplasts f. rough ER

  1. Bovine growth hormone (BGH) is a protein produced and secreted by cells of a cow's pituitary gland. Which of the following represents the correct pathway BGH takes as it is released from the pituitary gland cells? a. endocytosis --> transport vesicle --> rough ER --> transport vesicle --> smooth ER b. rough ER --> transport vesicle --> Golgi apparatus --> transport vesicle -- > exocytosis c. cytosol --> nucleus --> nuclear pores --> transport vesicles --> plasma membrane d. rough ER --> transport vesicle --> smooth ER --> lysosome --> plasma membrane e. rough ER --> transport vesicle --> Golgi apparatus --> transport vesicle --> lysosome --> plasma membrane --> exocytosis
  2. LIMPs are proteins found in the lysosomal membranes of some eukaryotic cells. Which of the following is/are zip code(s) needed for LIMPs to make it to their correct destination? Select all correct choices a. nuclear localization signal b. peroxisomal targeting signal c. ER signal peptide d. lysosomal targeting signal e. no signal is needed f. cytosol targeting signal g. mitochondrial targeting signal
  3. Which of the following supports the theory that mitochondria and chloroplasts evolved from prokaryotic cells? Mitochondria and chloroplasts. Select all correct answers a. have ribosomes that structurally resemble prokaryotic ribosomes b. have cell walls made of cellulose c. divide by binary fission d. have circular chromosomes e. are similar in size to typical prokaryotic cells
  4. Which of the following is/are accurate about peroxisomes? Select all correct choices a. Peroxisomes provide a compartment for oxidation reactions b. Peroxisomes break down molecules by hydrolysis c. Peroxisomes contain the enzyme catalase, which decomposes hydrogen peroxide either by converting it to water and oxygen d. Proteins found in the peroxisome have an ER signal peptide and a peroxisomal targeting signal
  5. Replication of eukaryotic chromosome begins a. on ribosomes b. anywhere in the chromosome

e. they are found at origins of replication f. they are found at the ends of chromosome g. they are shortened by telomerase h. they get longer as we age

  1. In lecture, we talked about three ways in which mistakes or mutations in DNA can be fixed. Match each mechanism with the appropriate statement(s). a. Proofreading -- occurs during DNA replication via DNA polymerase 3’ -> 5’ exonuclease capability b. Mismatch repair -- occurs immediately after a DNA strand is made; it detects and fixes incorrectly paired nucleotides c. Excision repair -- fixes DNA damage, such as thymine dimers, that can occur well after DNA replication is completed
  2. Which is the correct order in which enzymes work in excision repair? a. primase, DNA polymerase, methylase b. DNA polymerase, DNA ligase, nuclease c. nuclease, DNA polymerase, DNA ligase d. DNA polymerase, DNA ligase, primase, nuclease e. telomerase, DNA polymerase alpha, ligase
  3. Put the following levels of packing of eukaryotic chromosomes in order, starting with the loosest and going to the tightest/most condensed. i. Nucleosome ii. Double Helix iii. Metaphase chromosome iv. Looped domains v. 30nm fiber a. 5-3-4-2- 1 b. 3-4-5-1- 2 c. 3-2-4-1- 3 d. 2-1-5-4- 3 e. 1-2-4-5- 3