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Various medical topics related to bleeding time, platelet function, and other related conditions. It covers questions and answers from medical board exams, providing insights into the diagnosis, treatment, and management of conditions such as torsades, mitral stenosis, atrial fibrillation, pneumonia, zollinger-ellison syndrome, sjogren's syndrome, polymyalgia rheumatica, polymyositis, dermatomyositis, pseudogout, osteoarthritis, rheumatoid arthritis, osteoporosis, horner's syndrome, pelvic fractures, osteosarcoma, herpes simplex virus, fibroids, endometriosis, polycystic ovarian syndrome, down syndrome, and turner syndrome. The document aims to equip medical professionals with the knowledge and understanding required to effectively diagnose, treat, and manage these conditions.
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Boards Tip: If the question references "ascites" what medication should always be added? - Answer>>Spironolactone Boards: What drug is MOST important drug in reducing M/M for: a) CAD b) CHF - Answer>>CAD = BB CHF = ACE-inhibitor BOARD question: Which cholesterol lab has the GREATEST impact on M/M? (i.e. is the most important) - Answer>>HDL ("garbage truck") **what REMOVES all the "bad cholesterol" BOARD QUESTION: What is the LDL goal in a patient with METABOLIC syndrome? - Answer>>Goal LDL < 70 mg/dL BOARD question: What are the most common complications of HIGH TG? - Answer>>1. Development of CAD = excess TG contribute to production of excess LDL
OM6 = vegetable / corn oil, beef, chicken OM3 = fish oil, flax seed, tuna, salmon, walnuts BOARD question: Which of the following is a CONSISTENT predictor of DM, CAD and mortality: a) TG levels b) TC levels c) Total weight d) Waist circumference - Answer>>WAIST CIRCUMFERENCE (highest indicator of M/M) BOARD question: Which group has the HIGHEST prevalence of metabolic syndrome: a) AA b) Caucasians c) Hispanics d) Mexican Americans - Answer>>Mexican americans BOARD question: Which of the following is the MOST SENSITIVE predictor of CAD: a) TC level b) LDL levels c) ratio of TC to HDL d) C-reactive protein - Answer>>Ratio of TC to HDL BOARD question: Use of Niacin is associated with reduction in: a) CVA b) CABG c) CAD d) MI - Answer>>CAD
BOARD question: 65 yo male presents to ER with CP + SOB for last 7 minutes. Initial EKG & cardiac enzymes are negative. What is the most appropriate NEXT step in management: a) admit for ACS and head straight to cath lab b) discharge home with BB + ACEi c) Admit for ACS and schedule for treadmill stress test d) repeat EKG/enzymes in 2 hours - Answer>>Repeat tests in 2 hours BOARD question: Elevation of troponin is indicative of injury to what? a) blood vessels b) pericardium c) myocardium d) smooth muscle - Answer>>elevated troponin indicates = MYOCARDIAL injury BOARD Question: Patients with RCA (inferior MI) typcailly present with WHAT other symptoms besides chest pain: a) visual changes b) hypertension c) hypotension d) epigastric pain - Answer>>Epigastric pain (remember inferior portion of the heart sits on diaphragm) BOARDS: The prevalence of AFIB increases dramatically with: a) cardiac damage b) age c) ETOH intake d) smoking - Answer>>AGE
BOARDS (true or false): The natural tendency of AFIB is to become a CHRONIC condition.... - Answer>>TRUE BOARDS: What is the MOST IMPORTANT diagnostic test to order in a newly diagnosed AFIB patient: a) EKG b) TSH c) ECHO d) Angiogram - Answer>>TSH BOARDS: What is the most appropriate initial test to order in AFIB: a) TEE b) TTE c) CXR d) angiography - Answer>>BUZZ word is INITAL (answer) = TTE Initial = TTE BEST = TEE BOARDS: What agent is the most appropriate to use in a patient with AFIB + RVR secondary to hyperthyroidism: a) CCB b) BB c) Digoxin - Answer>>BB (answer) **remember that: a) AFIB d/t cardiac issue = CCB b) AFIB d/t non-cardiac issue = BB c) AFIB + HF = digoxin
d) Amilodipine - Answer>>Lidocaine **remember that for those who have (+) QT prolongation, they are at the highest risk for unstable cardiac arrhythmias --> so we ADD ventricular anti-arrhythmic (Class 1b) to reduce risk. BOARDS: What cardiac anomaly are you MOST worried about in a patient with history of a eating disorder: a) valvular abnormality b) QT prolongation c) LVH d) ischemia - Answer>>QT prolongation BOARD: In a patient with a new onset of murmur, what test should be ordered initially? a) ECHO b) Cardiac cath c) EKG - Answer>>KEY WORD = "initially" ECHO = INITAL test of choice CATH = DEFINITIVE diagnostic test (usually ordered if echo is inconclusive) BOARDS: A patient presents with sudden onset of angina. In ER they are given "NOBAM" and suddenly collapse. What is the most likely etiology for their syncope: a) MI b) CVA c) Aortic Stenosis d) orthostatic hypotension - Answer>>Aortic stenosis
"NTG makes AS go night-night" BOARDS: What type of MI is usually associated with new-onset of mitral regurgitation: a) Septal b) Lateral c) Inferior - Answer>>Inferior (RCA) BOARDS: A woman who has a history of using Phentermine/Fenfluramine (Phen-fen) is most likely to have which of the following cardiac abnormalities: a) AR b) MR c) TR d) PR - Answer>>TR BOARDS: What is the BEST health maintenance test to order in patients with history of anorexia and/or bulimia: a) CMP b) EKG c) ECHO d) DEXA - Answer>>This one is tricky because all of the following are GOOD tests because these patients are prone to hypocalcemia: -CMP -DEXA -EKG HOWEVER, the best (most critical) test is the annual EKG!! (hypocalcemia = predisposes you to QT prolongation = increased risk of VFIB)
Why? -remember that ACEi are contraindicated in patients with renal artery stenosis -classically if you miss RAS & place them on ACEi they will get worse BOARDS: Which patients have a higher incidence of nitroglycerine induced syncope? a) mitral stenosis b) mitral regurgitation c) aortic regurgitation d) aortic stenosis - Answer>>AS
In this cardiac problem, the RENIN level is elevated and causes an increase in BP: a) VSD b) PDA c) ASD d) Coarctation of aorta - Answer>>Coarctation of aorta BOARDS: Which of the following medications is contraindicated in patient with CAD: a) ATenolol b) Ditalizem c) HTCZ d) Lisinopril e) Sildenafil - Answer>>Sildenafil (viagra) BOARDS: A 85 yo male comes in with HTN + CAD complaining of chest pain. He is given NTG in ER and immediately has a syncopal episode. What is the next step in management? a) Angiogram b) CT scan c) MRI d) Stress test e) ECHO - Answer>>ECHO (most likely as aortic stenosis) BOARDS: Which of the following medications is the MOST important to given a patient with AFIB? a) Atenolol b) Diltazem c) NTG d) ASA
**realize that EBV is also a known cause, HOWEVER, it is not the most common. BOARDS: Elevation of cardiac biomarkers comes from injury to: a) myocardium b) pericardium c) blood vessels - Answer>>MYOCARDIUM (+) elevation w/ myocarditis, ACS (-) elevation w/ pericarditis BOARDS: Which of the following is the most important RF for thoracic & abdominal aortic aneurysms: a) CAD b) Smoking c) Connective tissue disorders d) HTN - Answer>>HTN BOARDS: Which medication has the greatest impact on SLOWING the progression of thoracic and/or abdominal aortic aneurysm: a) ASA b) ACEi c) BB d) NTG - Answer>>BB !!! (all patients should be placed on BB to LOWER BP & prevent further aneurysm enlargement) BOARDS: Which of the following is the MOST specific diagnostic finding related to Pericarditis: a) Sharp CP b) Elevated pulse c) Negative cardiac enzymes
d) ST elevation in all leads e) Pericardial friction rub - Answer>>ST elevation (all leads) BOARDS: In 80% of these patients (new onset) they will present with AFIB + "diastolic opening snap" + accentuated S1: a) MS b) MR c) AR d) AS - Answer>>MS BOARDS: Which is the most common heart abnormality in children: a) VSD b) PDA c) ASD d) Coarctation of aorta - Answer>>VSD BOARDS: A patient with HTN + CAD + AFIB comes in with multiple TIAs over the past 2 weeks and is currently normal. Which of the following tests should be ordered as part of the next step of management: a) INR b) PT c) MRI d) TEE - Answer>>TEE (most likely etiology = patent foramen oval (PFO)) BOARDS: You hear a "machine wash" murmur on PE. What is considered 1st line therapy: a) indomethacin b) high-flow O c) surgery
Patient has = AFIB + RVR Rate control options: a) BB (non-cardiac etiologies) b) CCB (for cardiac etiologies) BOARDS: Which of the following medications is the MOST IMPORTANT to give a patient with AFIB? a) Atenolol b) Ditalizem c) NTG d) ASA e) Coumadin - Answer>>COUMADIN (reduce thromboembolic risk) **remember that for: a) AFIB (non-valvular) = may use alternative agents b) AFIB (valvular) = always use COUMADIN BOARDS: A patient with ovarian cancer comes in with sudden onset of severe sub-sternal CP, which improves when she sits & leans forward. Which of the following is likely the culprit: a) Ketoconazole b) Doxorubicin c) Atenolol d) Metastasis - Answer>>answer = Doxorubicin (chemo agent) **she likely has PERICARDITIS secondary to her chemotherapy drug. BOARDS: Which of the following medications are CONTRAINDICATED during pregnancy:
a) Ampicillin b) Ketoconazole c) Indomethacin d) Tylenol - Answer>>INDOMETHACIN **remember that giving a prostaglandin inhibitor (i.e. NSAID) during pregnancy will cause PREMATURE closure of the ductus arteriosus!! DOC (pregnancy) = TYLENOL BOARDS: A mother brings in her infant complaining that he becomes blue & sweaty with feeding. What is most likely the etiology? a) VSD b) ASD c) TOF d) PDA - Answer>>TOF BOARDS: Which of the following PE findings is MOST SPECIFIC for DVT: a) leg erythema b) leg pain c) leg edema (circumference > 3cm) d) (+) homan's sign - Answer>>Leg edema (circumference > 3cm) BOARDS: Treatment for patient with DVT is using UFH with warfarin started on: a) at discharge b) on 2nd day c) 48hrs after starting heparin d) at the same time you start heparin - Answer>>AT SAME TIME
b) Protein C deficiency c) Protein S deficiency d) Factor V Leiden - Answer>>Factor V Leiden BOARDS: Which of the following tests would yield hte MOST RELIABLE results in diagnosing a PE: a) VQ scan b) CXR c) ABG d) Spiral Ct e) Doppler ultrasound f) D-dimer - Answer>>Spiral CT **but remember that pulmonary angiography (gold standard) BOARDS: A DM patients presents with suspected PE. What medication must be stopped BEFORE you can order the spiral CT: a) Aspirin b) Ace-inhibitor c) Metformin d) Insulin - Answer>>Metformin **remember that Spiral CT requires IV CONTRAST (which is metabolized via kidneys & has potential to be nephrotoxic) **combination of metformin + IV contrast = INCREASES risk of nephrotoxicity (so need to temporarily d/c metformin) BOARDS: Patients receiving Coumadin should have their INR checked every: a) 2 weeks b) 4 weeks c) 6 weeks
d) 8 weeks - Answer>>4 weeks Dabigatran (Pradaxa) is best used for which of the following patietns: a) CVA patient with h/o TIA b) DVT prophylaxis in a patient after hip surgery c) Prophylaxis for emboli in AFIB 2/2 aortic stenosis d) Prophylaxis for emboli in AFIB 2/2 non-valvular cause - Answer>>Prophylaxis for emboli in AFIB 2/2 non-valvular cause **remember: a) AFIB d/t valvular = COUMADIN b) AFIB d/t non-valvular = may use alternative agents BOARDS: Which of the following medications may interact with dabigitran: a) Ciprofloxacin b) Fluoxetine c) Simvastatin d) Carbamazepine - Answer>>CARBAMAZEPINE (remember this drug & antifungals "jack everything up.") BOARDS: What is considered frontline therapy for Thromboangiitis Obliterans: a) ASA b) Amilodipine c) Exercise d) Tobacco cessation - Answer>>Tobacco cessation BOARDS: Which of the below BEST distinguishes Restrictive from Obstructive airway disease: a) Restrictive disease the FEV1/FVC is normal b) Obstructive disease usually presents with chronic cough