Catechol-O-methyltransferase (COMT)
inhibitor, Entacapone
what it does - correct answer helps with voluntary movement control (levodopa
sidekick)
mechanism of action - correct answer selective/reversible inhibitor of COMT which
lets levodopa stay in blood and basal ganglia
adverse effects - correct answer rhabdomyolysis, dyskinesia, melanoma, orthostatic
hypotension, hallucinations, sleep disturbance, impulse control problems
nursing considerations - correct answer assess parkisons, extrapyramidal symptoms.
Monitor neuroleptic malignant syndrome and diarrhea
patient teaching - correct answer nausea/diarrhea/dizziness may occur, move around
to prevent orthostatic hypotension
patient teaching - correct answer report unusual skin
changes/hallucinations/pregnancy/intense urges
drug interactions - correct answer with levodopa, permits lower dose if effective
situations - correct answer parkinsons disease
route of admin - correct answer PO
on and off time - correct answer extends on time
