Cell Cycle Brainstorming, Study notes of Cell Biology

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2021/2022

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CELL CYCLE & CELL DIVISION
BRAINSTORMING
Cell cycle refers to the series of events that
results in the duplication of the cell along with
the DNA.
The stages of cell cycle include:
Interphase
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
4 major stages of mitosis:
prophase
metaphase
anaphase
telophase.
The different phases of a cell cycle include:
Interphase – This phase includes the G1
phase, S phase and the G2 phase.
M phase – This is the mitotic phase and
is divided into prophase, metaphase,
anaphase and telophase.
Cytokinesis – In this phase the
cytoplasm of the cell divides.
Who discovered cell cycle?
Walther Flemming discovered cell cycle
in the 19th century. He was a professor
at the Institute of Anatomy.
The importance of cell division:
It helps in the survival and growth of
organisms.
Maintenance of chromosome number.
Renewal of damaged cells
Which is the most important stage of cell cycle?
Interphase is the most important stage
of cell cycle. The cell stays in the
interphase for maximum periods.
During this phase the cell prepares itself
for division. The cell undergoes cell
growth and replication during this
phase.
What is the significance of G1, S and G2 phases
of the interphase?
During the G1 phase the cell continues
to grow but does not replicate.
During the S phase the DNA of the cell
replicates.
During the G2 phase the RNA, proteins
and other macromolecules required for
mitotic division are produced by the
cell.
G0 phase:
- These cells may exit the G1 phase and
enter a resting state called G0 phase.
-In G0, a cell is not actively preparing to
divide, it’s just doing its job. For
instance, it might conduct signals as a
neuron or store carbohydrates as a liver
cell.
-G0 is a permanent state for some cells,
while others may re-start division if
they get the right signals.
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BRAINSTORMING

Cell cycle refers to the series of events that

results in the duplication of the cell along with the DNA. The stages of cell cycle include:  Interphase  Prophase  Metaphase  Anaphase  Telophase  Cytokinesis 4 major stages of mitosis:  prophase  metaphase  anaphase  telophase. The different phases of a cell cycle include:  Interphase – This phase includes the G phase, S phase and the G2 phase.  M phase – This is the mitotic phase and is divided into prophase, metaphase, anaphase and telophase.  Cytokinesis – In this phase the cytoplasm of the cell divides. Who discovered cell cycle?  Walther Flemming discovered cell cycle in the 19th century. He was a professor at the Institute of Anatomy. The importance of cell division:  It helps in the survival and growth of organisms.  Maintenance of chromosome number.  Renewal of damaged cells Which is the most important stage of cell cycle?  Interphase is the most important stage of cell cycle. The cell stays in the interphase for maximum periods. During this phase the cell prepares itself for division. The cell undergoes cell growth and replication during this phase. What is the significance of G1, S and G2 phases of the interphase?  During the G1 phase the cell continues to grow but does not replicate.  During the S phase the DNA of the cell replicates.  During the G2 phase the RNA, proteins and other macromolecules required for mitotic division are produced by the cell. G0 phase:

  • These cells may exit the G 1 phase and enter a resting state called G0 phase.
  • In G 0 , a cell is not actively preparing to divide, it’s just doing its job. For instance, it might conduct signals as a neuron or store carbohydrates as a liver cell.
  • G 0 is a permanent state for some cells, while others may re-start division if they get the right signals.

KEY POINTS:

 During Prophase , the nucleus

disappears, spindle fibers form, and DNA condenses into chromosomes (sister chromatids).

 During Metaphase , sister chromatids

align along the middle of the cell by attaching their centromeres to the spindle fibers.

 During Anaphase , sister chromatids

physically separate at the centromere and pull towards opposite poles of the cell by the mitotic spindle.

 During Telophase , chromosomes

arrive at opposite poles and unwind into thin strands DNA, the spindle fibers disappear, and the nuclear membrane reappears.

 Cytokinesis is the actual splitting of

the cell membrane; animals cells pinch apart, while plant cells form a cell plate that becomes the new cell.  Cell enter the G0 (inactive) phase after they exit the cell cycle when they are not actively preparing to divide; some cells remain in G0 phase permanently.

KEY TERMS:

 Centrosome: an organelle near the

nucleus in the cytoplasm of most organisms that control the organization of its microtubules and gives rise to the mitotic spindle.

 Cytokinesis: The second portion of the

mitotic phase in which the cytoplasm of a cell divides following the division of the nucleus.

 Nuclear Membrane: The membrane

around the nucleus.

 Cell Plate: where plant cells divide

when new cell wall are made.

 Mitotic Spindle: the apparatus that

orchestrates the movements of chromosomes during mitosis.

 Sister chromatids : the identical copies

formed by the DNA replication of a chromosomes.

 Centrosome: an organelle near the

nucleus of a cell that contains centrioles (in animal cells) and from which the spindle fibers develop in cell divisions.