Cell Membrane Structure and Function, Exams of Nursing

A comprehensive overview of the structure and function of the cell membrane, covering key concepts such as the fluid mosaic model, amphipathic properties of phospholipids, and the role of various membrane components like proteins, cholesterol, and organelles. It delves into the mechanisms of membrane fluidity, transport processes, and the techniques used to study cell membranes, including electron microscopy and cell fractionation. The document serves as a valuable resource for students studying topics related to cell biology, biochemistry, and molecular biology, offering insights into the fundamental principles governing the organization and dynamics of the cell membrane, a crucial structure for cellular function and homeostasis.

Typology: Exams

2023/2024

Available from 09/27/2024

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Biol-1406 Exam 2 (Campbell Biology
Ch.5-7)
Amphipathic - correct answer Having hydrophilic and hydrophobic regions; phospholipids are this
Overton (Overton's Rule) - correct answer The more lipophilic the molecule, the faster it will diffuse into
cell (thus cell membrane has lipid areas)
Langmuir - correct answer Phospholipids have polar heads and nonpolar tails ("Langmuir's lemurs have
tails")
Gorter & Grendel - correct answer Membranes have a phospholipid BILAYER ("the two Gs found two
layers")
Davson & Danielli - correct answer Sandwich Model of Membrane - layer of protein over phospholipid
membrane ("Davson and Danielli Deli")
Singer & Nicolson - correct answer Fluid Mosaic Model - proteins are embedded into phospholipid layer
("I'd give a nickel for a song about this mosaic model")
What is the fluidity of a membrane controlled by? (2) - correct answer -Fatty Acid (lipid) concentration
-Cholesterol (prevents excess fluidity at high temp and excess viscosity at low temp)
Scanning Electron Microscope (SEM) - correct answer Used to study topography of a specimen, 3-D
image
Transmission Electron Microscope (TEM) - correct answer Used to study internal structure of cells, thin
layer of stained specimen is viewed
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Biol-1406 Exam 2 (Campbell Biology

Ch.5-7)

Amphipathic - correct answer Having hydrophilic and hydrophobic regions; phospholipids are this Overton (Overton's Rule) - correct answer The more lipophilic the molecule, the faster it will diffuse into cell (thus cell membrane has lipid areas) Langmuir - correct answer Phospholipids have polar heads and nonpolar tails ("Langmuir's lemurs have tails") Gorter & Grendel - correct answer Membranes have a phospholipid BILAYER ("the two Gs found two layers") Davson & Danielli - correct answer Sandwich Model of Membrane - layer of protein over phospholipid membrane ("Davson and Danielli Deli") Singer & Nicolson - correct answer Fluid Mosaic Model - proteins are embedded into phospholipid layer ("I'd give a nickel for a song about this mosaic model") What is the fluidity of a membrane controlled by? (2) - correct answer -Fatty Acid (lipid) concentration -Cholesterol (prevents excess fluidity at high temp and excess viscosity at low temp) Scanning Electron Microscope (SEM) - correct answer Used to study topography of a specimen, 3-D image Transmission Electron Microscope (TEM) - correct answer Used to study internal structure of cells, thin layer of stained specimen is viewed

Cell Fractionation - correct answer Separate cell organelles and other structures from one another with differential centrifugation (separates based on size and density) Cytosol - correct answer Jelly-like fluid that suspends subcellular components Mycoplasma - correct answer Very small bacterium with diameter between .1 um and 1 um Nuclear Lamina - correct answer Array of protein filaments (called intermediate filaments in animals) located on the inner side of nuclear membrane that maintains shape of nucleus Nuclear Matrix - correct answer Array of protein fibers throughout nucleoplasm that organizes genetic material Free Ribosomes - correct answer In Cytosol, produces proteins (ex. enzymes) for use in cytosol Bound RIbosomes - correct answer Produces protein enzymes for membranes, organelles, or secretion (ex. digestion) Vesicles - correct answer Sacs made of membrane Endoplasmic Reticulum and its parts (Cisterna, Lumen) - correct answer Network (reticulum) of membranes inside a cell (endoplasmic) made up of tubules and sacs (cisterna) that form cavities of space (lumen) separated from cytosol Smooth ER - correct answer Lacks ribosomes (smooth); Functions include producing lipids (oils, steroids (hormones), membrane phospholipids), producing detoxifying enzymes, and storing calcium ions. Rough ER - correct answer Secretes glycoproteins (proteins bonded to carbohydrates) that leave via transport vesicles and produces membranes Golgi apparatus - correct answer Material carried by vesicles move from Cis side (facing ER which is also membrane, same) to Trans side.