Chemical Sterilization, Lecture notes of Microbiology

Download Chemical Sterilization and more Lecture notes Microbiology in PDF only on Docsity!

7. PLATERNARY Ammonium CcomPounDs. Quatetnary ammonium compounds have broad spectrum ontimicrobial activity erie are effective disinfectants used fo¥ decontamination Pureoses: Ft has @ low toxicit hi h solubility ia cal DN J water, stability 19 solubion and noncottosive ne ss Most compounds of the germicical cationic - detergent laces ave quaternary a the ackericidal Powey of the eyuaternaries fis eaccee tionally \igh against Grrampositive bacteria, land they até also quite active against Gram guoteinaries have been shown negative OTganisms: wall as destauctive to certain lke be Sungicidal as of the pabhogenic protezea: cH fa Vi a ae ey! cM b Cr¥on- CY9w- “ae 33 n©2n-1 ; cH3 mmonium salts. cé TILPYRIAMIOM Bew2arkenu™ Mo0G OF AcTioN OF QUATERNARY Ammonium com PoOWOS: Shere ate AiPerest mode of action of Quaternory Aracnoniun Compound these \nclude cdensturation of Proteins, interference with glycolysis and membiane damage - experimental evidence su, gests that the most likely site of the damage to the cell is Lhe cytoplasmic mermbiane, the quatetnaries Ape eEyA features of this call structute. pas a\ Rermea biti by