Compare and Contrast, Summaries of Endocrinology

Comparing and contrasting pathophysiology between diverticulitis and diverticulosis

Typology: Summaries

2023/2024

Uploaded on 10/16/2024

kimberly-allen
kimberly-allen 🇺🇸

1 document

1 / 2

Toggle sidebar

This page cannot be seen from the preview

Don't miss anything!

bg1
1. Compare and contrast the pathophysiology between diverticular disease
(diverticulosis) and diverticulitis.
Reviewing several articles regarding diverticular disease (DD), the common
thread amongst medical professionals regarding its pathophysiology is not truly
understood. Scientists all agree that there are many contributors to the cause of
DD such as colonic wall structure deviations, motility, the amount of food that is
ingested, and obesity without physical activities (Piscopo and Ellul, 2020).
McCance textbook also states that pre-disposessing factors for this condition
also can include genetics, obesity, diet, medications, and age. Old school
thought was that nuts, seeds, corn, and popcorn were also contributors to acute
diverticulitis, however, more studies have recently come out that deny that
assumption (El-Sayed et al., 2018).
Diverticulitis results from micro and macro perforations that occur in the
diverticular wall. These can be caused by increased pressure from food particles
remaining in the diverticulum that, over time erodes the lining of the diverticular
wall. Eventually, not always, these erosions can lead to formations of abscesses
or obstructions (Linzay and Pandit, 2023).
2. Identify the clinical findings from the case that support a diagnosis of acute
diverticulitis.
Pt is elderly with a past medical history of diverticular disease. She presented with left
lower quadrant pain. Her low-grade fever is indicative of infection, as well as the
nausea and vomiting with constipation.
Her abdomen is distended, round, and tender to touch. Bowel sounds are hypoactive
with a hyper resonance upon percussion.
3. List 3 risk factors for acute diverticulitis.
1. Excess use of aspirin, COX inhibitors, and NSAIDS
2. Aging/elderly (>60), obesity
3. physical activity or lack thereof, dietary intake such as nuts, corn, and popcorn
consumption, smoking
4. Discuss why antibiotics and IV fluids are indicated in this case.
pf2

Partial preview of the text

Download Compare and Contrast and more Summaries Endocrinology in PDF only on Docsity!

  1. Compare and contrast the pathophysiology between diverticular disease (diverticulosis) and diverticulitis.  Reviewing several articles regarding diverticular disease (DD), the common thread amongst medical professionals regarding its pathophysiology is not truly understood. Scientists all agree that there are many contributors to the cause of DD such as colonic wall structure deviations, motility, the amount of food that is ingested, and obesity without physical activities (Piscopo and Ellul, 2020). McCance textbook also states that pre-disposessing factors for this condition also can include genetics, obesity, diet, medications, and age. Old school thought was that nuts, seeds, corn, and popcorn were also contributors to acute diverticulitis, however, more studies have recently come out that deny that assumption (El-Sayed et al., 2018). Diverticulitis results from micro and macro perforations that occur in the diverticular wall. These can be caused by increased pressure from food particles remaining in the diverticulum that, over time erodes the lining of the diverticular wall. Eventually, not always, these erosions can lead to formations of abscesses or obstructions (Linzay and Pandit, 2023).
  2. Identify the clinical findings from the case that support a diagnosis of acute diverticulitis. Pt is elderly with a past medical history of diverticular disease. She presented with left lower quadrant pain. Her low-grade fever is indicative of infection, as well as the nausea and vomiting with constipation. Her abdomen is distended, round, and tender to touch. Bowel sounds are hypoactive with a hyper resonance upon percussion.
  3. List 3 risk factors for acute diverticulitis.
  4. Excess use of aspirin, COX inhibitors, and NSAIDS
  5. Aging/elderly (>60), obesity
  6. physical activity or lack thereof, dietary intake such as nuts, corn, and popcorn consumption, smoking
  7. Discuss why antibiotics and IV fluids are indicated in this case.

Acute diverticulitis indicates inflammation/infection with a possible micro-perforation of the colon wall/diverticulum. Since this patient’s CT scan was negative for masses or obstruction, and due to her increased age, treating her with intravenous (IV) fluids inpatient to restore needed fluids with antibiotics piggy-backed is appropriate. References: El-Sayed C, Radley S, Mytton J, Evison F, Ward ST. Risk of Recurrent Disease and Surgery Following an Admission for Acute Diverticulitis. Dis Colon Rectum. 2018 Mar;61(3):382-389. [PubMed] Linzay CD, Pandit S. Acute Diverticulitis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459316/ McCance, S.H. K. ([Insert Year of Publication]). Pathophysiology (8th ed.). Elsevier Health Sciences (US). https://online.vitalsource.com/books/

Piscopo, N., & Ellul, P. (2020). Diverticular Disease: A Review on

Pathophysiology and Recent Evidence. The Ulster medical journal , 89 (2),