Composition of cells, Study notes of Biology

An overview of the structure and function of cells. It explains the different parts of a cell, including the nucleus, cytoplasm, and cell membrane, and their roles in carrying out metabolic activities and specialized functions. The document also discusses the composite cell, the structure of the plasma membrane, and the cytoskeleton. Additionally, it covers the different organelles found in the cytoplasm, such as ribosomes, endoplasmic reticulum, vesicles, Golgi, mitochondria, lysosomes, and peroxisomes. Finally, it explains the structure and function of the cell nucleus, including chromatin and nuclear pores.

Typology: Study notes

2021/2022

Available from 02/21/2023

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Lecture 2
Cell:
- A cell is the smallest unit of life
- Continually carries out metabolic activities essential for life,
as well as specialized function and adapts to changing
conditions
- Form organs and organ system
-Genes control a cell’s action and response
-Different in cell shape makes different function
Composite cell
-We put these cell structure together to study
-Most cell contain most of these structures, but no cell
contain everything in a composite cell
- Three main parts:
oNucleus: Contain DNA and direct cells activity
oCytoplasm: Organelles and fluid make up the majority
if the cell (in between)
Organelles are suspended in a fluid called the
cytosol
oCell membrane: Boundary that encloses the cell
Boundary that contain the cell contents
Regulates the movement of substances in and out of the cell
Extremely thin, flexible and elastic
Selectively permeable
Has complex surface features; with adaptations to increase surface area
Structure of the plasma membrane
- Composed mainly of lipids and proteins and
some CHO
- Consists of a double layer of phospholipids,
with fatty acid tails turned inward and the
water-soluble heads facing the surfaces
- Lipid soluble molecules can pass though the
phospholipid portion of the membrane
- Impermeable to water soluble molecules
-Glycoproteins is used for cell identification
-Cytoskeleton will anchor supportive rods and tubules; give the cell the shape
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Lecture 2 Cell:

  • A cell is the smallest unit of life
  • Continually carries out metabolic activities essential for life, as well as specialized function and adapts to changing conditions
  • Form organs and organ system
  • Genes control a cell’s action and response
  • Different in cell shape makes different function Composite cell - We put these cell structure together to study - Most cell contain most of these structures, but no cell contain everything in a composite cell
  • Three main parts: o Nucleus : Contain DNA and direct cells activity o Cytoplasm : Organelles and fluid make up the majority if the cell (in between)  Organelles are suspended in a fluid called the cytosol o Cell membrane : Boundary that encloses the cell  Boundary that contain the cell contents  Regulates the movement of substances in and out of the cell  Extremely thin, flexible and elastic  Selectively permeable  Has complex surface features; with adaptations to increase surface area Structure of the plasma membrane
  • Composed mainly of lipids and proteins and some CHO
  • Consists of a double layer of phospholipids, with fatty acid tails turned inward and the water-soluble heads facing the surfaces
  • Lipid soluble molecules can pass though the phospholipid portion of the membrane
  • Impermeable to water soluble molecules
  • Glycoproteins is used for cell identification
  • Cytoskeleton will anchor supportive rods and tubules; give the cell the shape

The Cytoplasm

- Makes up the most volume, consists of cytosol, supportive cytoskeleton and networks of membrane and organelles. - Ribosomes : compose of RNA and protein; use for protein synthesis o free ribosomes -> use in the cell - Endoplasmic reticulum (ER): functions as a transport network throughout the cell o 2 types: RER and SER  RER – contain ribosomes and function in protein synthesis  SER - No ribosomes, function in lipid synthesis and absorption of fats and metabolism of drugs

  • Vesicles: Membrane sacs; Store or transport substances within or between cells
  • Golgi: Refines, packages, and transports proteins formed in the RER
  • Mitochondria: folded -> increase SA -> more enzymes to make ATP o There is Bacteria in the cell to make ATP (a symbiotic relationship)
  • Lysosomes: contain enzymes that break down nutrients, toxins
  • Peroxisomes: Lysosomes that have different enzymes -> breakdown fatty acids and detoxification alcohol Other cellular structures
  • Centrosome : non membrane structure; function in the distribution of chromosomes during cell division
  • Cilia : move mucus back up so that it will not block air way
  • Flagella: allow the sperm to move The cell nucleus - Contain genetic material DNA - Surrounded by a double layered nuclear envelope, containing nuclear pores that allow the passage of certain substances - Contains a fluid called nucleoplasm - Chromatin consists of loosely coiled fiber of protein and DNA found in the nucleus; condensed DNA = chromosomes Centrosome Flagella Cilia

 Telophase -> final stage, nuclear envelope and nucleolus assemble, spindle fibers dissemble, turn back to chromatin Cell division: 2 type

- Meiosis: only use for sperm and egg cell production - Cell division: increase cell number of cells o Mitosis -> division of the nucleus o Cytokinesis -> division of the cytoplasm Cell differentiation - Certain gene got turn on and off - Allow cells to specialize by using different part of the complete genome that is present in each cell - Stem cells: retain the ability to divide without specialization -> make sure there is enough for continuous growth and renewal - Progenitor cells: daughter of stem cells that are partially specialized Cell death

  • Apoptosis -> normal part of development
  • Removes overgrown tissues, damaged cells
  • Steps of Apoptosis: o Cell becomes rounded and bulges o Nuclear membrane breaks down o Chromatin condenses and enzymes cut up the chromosomes o Cell shatters into many membrane-bound pieces o Scavenger cells engulf and destroy the fragments