The Biological Functions
of
Copper
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Copper, Milestones Along the Trail of Copper, Biological Roles for Copper, Neurological Functions, Lipid Metabolism, Growth Response to Dietary Copper, Symptoms of Copper Deficiency, Neurological Impairment, Aortic Aneurysm, Multicopper Oxidases with Ferroxidase Properties are lecture layout.
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2011/2012
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The Biological Functions
of
Copper
W. African Turaco
- 3d
- 3d
Biological Roles for Copper
Biological Function Biochemical Agent
Antioxidant activity
Bone strength
Cardiovascular
Electron transfer energy
Hematopoiesis
Lipid metabolism
Oxygen transport
Neurological functions
Neurohormone synthesis
Pigmentation
CuZnSOD, ceruloplasmin Lysyl oxidase Lysyl oxidase Cytochrome c oxidase Hephaestin, ceruloplasmin Fattyacyl desaturase Hemocyanin Dopamine monooxygenase Peptidyl--amidating enz Tyrosinase
Dopamine
- monooxygenase
Tyrosinase
Multicopper oxidases (ferroxidase)
Cytochrome c oxidase
Ascorbate oxidase
Amine oxidase (lysyl oxidase)
Superoxide dismutase
Symptoms of Copper Deficiency in Animals
- Stunted growth, arrested development
- Sway back (sheep and goats)
- Iron-resistant anemia
- Hypercholesterolemia
- Aortic rupture (falling disease)
- Loss of pigmentation
- Connective tissue weakness
- Inflammatory distress
- Neutropenia
10.Neurological impairment
Aortic Rupture
Eleven-day chick raised on Cu-deficient diet
Aortic Aneurysm
Weakened aorta
Eight-day Cu-Deficient Chick Aorta
Crosslinking
Response of Lysyl Oxidase to a Cu-deficient diet
Purified Plasma
Ceruloplasmin
Blue Copper (Type 1) Center and Trinuclear (Type 2 + Type 3)