Disturbances in Circulation, Slides of Pathology

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DISTURBANCES

in

CIRCULATION

C H A P T E R 4

P R E P A R E D B Y : J E S H A I S S A L E N A G O O D E S T A C I O

Edema

Normal lungs (gross) Edematous lungs (gross)

Description:

The plural surface is smooth and shiny with a

color of pink all throughout.

Description:

The lobes of the lung are firm, fail to collapse,

have an irregular surface that is mottled pink to

dark red, and a frothy clear fluid is seen on the cut

surface.

Congestion

Normal spleen (gross) Congested spleen (gross)

Description:

The normal splenic surface is smooth and with a

dark red color all throughout.

Description:

The spleen is enlarged, deeply congested with a

thickened capsule. The section surface showed a

graytan in color parenchyma.

Normal spleen (microscopic) Congested spleen (microscopic)

Description: Hematoxylin and Eosin, 12.5x

The parenchyma of the spleen is organized

into red and white pulp and the trabeculae

extend inward from the capsule which is seen

throughout the red pulp.

Description: Hematoxylin and Eosin, 25x

The sinuses appeared dilated and congested

and there is an increased fibrosis seen in the

red pulp. There is also a thickened capsule and

trabeculae seen.

Normal lungs (microscopic) Hemorrhagic lungs (microscopic)

Description: Hematoxylin and Eosin

The normal lung section has an alveoli which has

thin walls, clear or empty lumen, and there are

no thickening or fibrosis of the interstitium.

Description: Hematoxylin and Eosin

The section shows alveolar lumina with variable

amounts of hemorrhage, fibrin and edema. There

is a disruption of alveolar septa and it is

segmentally expanded by congestion and edema.

Thrombosis

Normal lungs (gross) Lungs with thrombus (gross)

Description: Lung, Cow

The normal lung shows no thickening or fibrosis

and has a red color.

Description: Lung, Cow

The lung has variably sized raised, yellow to pale

red dry areas (necrosis) with marked interlobular

fibrosis and enlarged thrombosed lymph vessels.

Infarction

Normal kidney (gross) Infarcted kidney (gross)

Description:

The normal kidney has a reddish-brown color and

shows visible margins between medullary

pyramids.

Description:

The kidney is mottled dark red and there are large

wedge shaped areas of acute infarction

characterized by hemorrhage and coagulative

necrosis of the cortex and medulla.

Normal kidney (microscopic) Infarcted kidney (microscopic)

Description: Glomerulus, Hematoxylin and Eosin

The normal kidney section shows a clear capsular

space, distinct glomerular capillaries, and visible

renal (distal) tubule lumen.

Description: Glomerulus, Hematoxylin and Eosin

The cells in the infarcted area show loss of cellular

detail. The glomeruli contains an abundant fibrin

within the glomerular capillaries occupying the

whole glomerular space and the renal tubules are

necrotic wherein epithelial cells are

hypereosinophilic and slough into the lumen.