Dosage Calculations., Exams of Pharmacy

Dosage calculations are used to determine the correct amount of a medicine a patient should receive, the quantity to supply, and the duration of treatment. The aim is to ensure the patient receives an effective dose while minimizing underdosing or overdosing.

Typology: Exams

2025/2026

Available from 05/31/2026

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DOSE CALCULATIONS.
1.Calculating quantities needed to prescribe:
Tablets or capsules: This is fairly straightforward as you know how many tablets the patient
needs to take and how long you need to give them. It can get more tricky however with
variable dosage. Here are 2 examples of more complicated dosage quantity calculations:
1. A patient with brittle asthma requires a reducing course of prednisolone back to
maintenance dose of 5mg following an acute exacerbation. You prescribe the following
regimen, calculate how many prednisolone 5mg tablets are required to get back to
maintenance dose.
40mg daily for 5 days then
30mg daily for 5 days
25mg daily for 3 days
20mg daily for 3 days
15mg daily for 2 days
10mg daily for 2 days
then 5mg maintenance as before
2. A patient is on warfarin for atrial fibrillation. You prescribe a new dosage regimen based on their
latest INR result: Take 4mg daily Mon-Fri and 5mg daily Sat/Sun. Warfarin comes as 1mg, 3mg and
5mg tablets. Calculate the quantity you would need for a 28-day supply.
Inhalers and sprays: You would need to know how many dosage units are in each inhaler or spray and
know the strength of the dosage unit, the frequency and duration of treatment.
3. A patient requires 200 dose beclometasone nasal spray 50 micrograms for hay fever. The dose is 2
sprays in each nostril twice a day, how long should the spray last?
4. How long will the eye drops for glaucoma in the following prescription last?
Bimatoprost ophthalmic solution
1 drop once daily in both eyes at night
Supply 5ml
Answers
1 = 107
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DOSE CALCULATIONS.

1.Calculating quantities needed to prescribe: Tablets or capsules: This is fairly straightforward as you know how many tablets the patient needs to take and how long you need to give them. It can get more tricky however with variable dosage. Here are 2 examples of more complicated dosage quantity calculations:

  1. A patient with brittle asthma requires a reducing course of prednisolone back to maintenance dose of 5mg following an acute exacerbation. You prescribe the following regimen, calculate how many prednisolone 5mg tablets are required to get back to maintenance dose. 40mg daily for 5 days then 30mg daily for 5 days 25mg daily for 3 days 20mg daily for 3 days 15mg daily for 2 days 10mg daily for 2 days then 5mg maintenance as before
  2. A patient is on warfarin for atrial fibrillation. You prescribe a new dosage regimen based on their latest INR result: Take 4mg daily Mon-Fri and 5mg daily Sat/Sun. Warfarin comes as 1mg, 3mg and 5mg tablets. Calculate the quantity you would need for a 28 - day supply. Inhalers and sprays: You would need to know how many dosage units are in each inhaler or spray and know the strength of the dosage unit, the frequency and duration of treatment.
  3. A patient requires 200 dose beclometasone nasal spray 50 micrograms for hay fever. The dose is 2 sprays in each nostril twice a day, how long should the spray last?
  4. How long will the eye drops for glaucoma in the following prescription last? Bimatoprost ophthalmic solution 1 drop once daily in both eyes at night Supply 5ml Answers 1 = 107

2 = 1mg + 3mg = 4mg daily dose, 5 days a week, = 20 x 1mg, 20 x 3mg. 5mg daily dose 2 days per week = 8 x 5mg (Note: in practice patients would probably have a surplus of tablets supplied as a 28 day pack so if dosage changes they can easily adjust) 3 = 25 days (2 sprays x 2 each time = 4 x 2 (twice daily) = 8 then 200/8 = 25 days) 4 = The patient will use 2 drops per day. Assume 1 mL = 20 drops and, then, 5 mL = 100 drops

2. Titrate dose upwards by 30-50% increments to relieve pain or until unacceptable side

effects occur. Always check the pain is opioid sensitive. A 65-year-old patient with lung cancer and bone metastases is taking MST 40mg bd, movicol and ibuprofen. Over the last week he has required on average 3 doses per 24 hrs of 10mg of oramorph for break through pain in his chest. The oramorph works well for the pain after about ½ hour and he has no adverse effects. What is the most suitable management plan? Increase MST by either 30% - 50% (50 or 60ng BD) or to account for frequent breakthrough doses, he's had an extra 30mg per day making total oral morphine, including MST, 110mg, in practice this would be rounded up to 12 0mg so that MST 60mg 12 hourly can be given. A breakthrough dose would therefore increase to 120mg/6 = 20mgL