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Dosage calculations are used to determine the correct amount of a medicine a patient should receive, the quantity to supply, and the duration of treatment. The aim is to ensure the patient receives an effective dose while minimizing underdosing or overdosing.
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1.Calculating quantities needed to prescribe: Tablets or capsules: This is fairly straightforward as you know how many tablets the patient needs to take and how long you need to give them. It can get more tricky however with variable dosage. Here are 2 examples of more complicated dosage quantity calculations:
2 = 1mg + 3mg = 4mg daily dose, 5 days a week, = 20 x 1mg, 20 x 3mg. 5mg daily dose 2 days per week = 8 x 5mg (Note: in practice patients would probably have a surplus of tablets supplied as a 28 day pack so if dosage changes they can easily adjust) 3 = 25 days (2 sprays x 2 each time = 4 x 2 (twice daily) = 8 then 200/8 = 25 days) 4 = The patient will use 2 drops per day. Assume 1 mL = 20 drops and, then, 5 mL = 100 drops
effects occur. Always check the pain is opioid sensitive. A 65-year-old patient with lung cancer and bone metastases is taking MST 40mg bd, movicol and ibuprofen. Over the last week he has required on average 3 doses per 24 hrs of 10mg of oramorph for break through pain in his chest. The oramorph works well for the pain after about ½ hour and he has no adverse effects. What is the most suitable management plan? Increase MST by either 30% - 50% (50 or 60ng BD) or to account for frequent breakthrough doses, he's had an extra 30mg per day making total oral morphine, including MST, 110mg, in practice this would be rounded up to 12 0mg so that MST 60mg 12 hourly can be given. A breakthrough dose would therefore increase to 120mg/6 = 20mgL