ELSEVIER-ANESTHESIA CORRECTLY ANSWERED, Exams of Advanced Education

ELSEVIER-ANESTHESIA CORRECTLY ANSWERED

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ELSEVIER-ANESTHESIA
ALL INDIA 2008
1. Train of four fade is characteristic feature of:
A. Non depolarizing block
B. Depolarizing block
C. Malignant hyperthermia
D. Both depolarizing and non-depolarizing block - CORRECT ANSWER A. Non
depolarizing block
2. Not True regarding sevoflurane:
a. MAC is higher than isoflurane
b. Blood gas coefficient is higher than desflurane
c. Potency more than isoflurane
d. Sevoflurane is less cardio depressant than isoflurane - CORRECT ANSWER c.
Potency more than isoflurane
Minimum alveolar concentration (MAC):
This is a measure of potency. It is defined as "at steady-state, the minimum alveolar
concentration of the volatile anaesthetic that prevents reaction to standard surgical
stimuli (skin incision) in 50 per cent of subjects at sea level (1 atm).
According to MAC value:
Desflurane> Sevoflurane > Enflurane > Isoflurane > Halothane
That is Halothane is the most potent. and Desflurane is the least potent.
According to the B/G coefficient
Desflurane < Sevoflurane < Isoflurane < Enflurane < Halothane.
3. Which of the following statements about propofol is not true:
A. Commercial preparations contains egg
B. It is suitable agent for day care surgery
C. It is contraindicated in porphyria
D. It does not trigger malignant hyperthermia - CORRECT ANSWER C. It is
contraindicated in porphyria
AIIMS MAY 2008
4. Order of sensitivity of nerve fibres to local anaesthetic in decreasing order -
A. Preganglionic sympathetic (B), pain (C and A-delta), sensory, motor
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ELSEVIER-ANESTHESIA

ALL INDIA 2008

  1. Train of four fade is characteristic feature of: A. Non depolarizing block B. Depolarizing block C. Malignant hyperthermia D. Both depolarizing and non-depolarizing block - CORRECT ANSWER A. Non depolarizing block
  2. Not True regarding sevoflurane: a. MAC is higher than isoflurane b. Blood gas coefficient is higher than desflurane c. Potency more than isoflurane d. Sevoflurane is less cardio depressant than isoflurane - CORRECT ANSWER c. Potency more than isoflurane Minimum alveolar concentration (MAC): This is a measure of potency. It is defined as "at steady-state, the minimum alveolar concentration of the volatile anaesthetic that prevents reaction to standard surgical stimuli (skin incision) in 50 per cent of subjects at sea level (1 atm). According to MAC value: Desflurane> Sevoflurane > Enflurane > Isoflurane > Halothane That is Halothane is the most potent. and Desflurane is the least potent. According to the B/G coefficient Desflurane < Sevoflurane < Isoflurane < Enflurane < Halothane.
  3. Which of the following statements about propofol is not true: A. Commercial preparations contains egg B. It is suitable agent for day care surgery C. It is contraindicated in porphyria D. It does not trigger malignant hyperthermia - CORRECT ANSWER C. It is contraindicated in porphyria AIIMS MAY 2008
  4. Order of sensitivity of nerve fibres to local anaesthetic in decreasing order - A. Preganglionic sympathetic (B), pain (C and A-delta), sensory, motor

B. Pain (C and A-delta), Preganglionic sympathetic (B), motor C. Preganglionic sympathetic (B), sensory, motor, pain (C and A-delta) D. Pain (C and A-delta), sensory, motor - CORRECT ANSWER A. Preganglionic sympathetic (B), pain (C and A-delta), sensory, motor. ∙∙ In functional terms, it is autonomic (mediated by C and B fibers) → Sensory ( mediated by C and A-delta fibers) → Motor ( A-alpha fibers). This is the old concept: NEWER CONCEPT: ∙ Sensitivity to Local Anaesthetic : A gamma & A delta > A alpha & A beta > B > C Miller's Anaesthesia. "Different fiber types are differentially sensitive to local anesthetic blockade. In vivo experiments in which continuous superperfusion of peripheral nerve allows equilibration with drug and experiments in which a drug bolus is delivered by percutaneous injection, analogous to clinical peripheral nerve block, show unequivocally that small myelinated axons (Aγ motor and Aδ sensory fibers) are the most susceptible to impulse annihilation. Next in order of block are the large myelinated (Aα and Aβ) fibers, and the least susceptible are the small, nonmyelinated C fibers. In fact, in this last group, impulses in the slowest conducting population (conduction velocity of 0.5 to 0.8 msec) are the most resistant to local anesthetic.

  1. All are safety features in anaesthesia machine except: a. Each gas is housed in an independent color coded, pin specific module b. Medium priority alarm shall be activated within 5 sec when the oxygen pressure decreases below a manufacturer- specific threshold pressure. c. Agent specific filling devices help to prevent filling vaporizer with the wrong agent d. The oxygen flowmeter's output changes accordingly when the supply pressure exceeds above the threshold valve. e. The oxygen flowmeter's output changes accordingly above the threshold valve. - CORRECT ANSWER d. The oxygen flowmeter's output changes accordingly when the supply pressure exceeds above the threshold valve. ALL INDIA 2007
  2. Which one of the following is not an amide linked local anaesthetic:
  1. It has rapid onset of action, a small volume of distribution and clearance and terminal half life 8 to 20 min
  2. It is 10 to 20 times more potent than alfentanil
  3. Little change of blood pressure
  4. It can cause muscle rigidity (wood chest syndrome)
  5. Centrineuraxial (spinal and epidural) anaesthesia is not contraindicated in- A. Patient on aspirin B. Platelets < 80, C. Raised intracranial pressure D. Patient on oral anticoagulants - CORRECT ANSWER A. Patient on aspirin There are three drugs commonly used in the United States to produce spinal anesthesia: lidocaine (Xylocaine), tetracaine (Pontocaine), and bupivacaine (Marcaine or Sensorcaine). ∙∙ Lidocaine provides a short- to intermediate-acting spinal drug ∙∙ Tetracaine and bupivacaine provide intermediate- to long-duration block
  6. Which of the following is not used in controlling heart rate intraoperatively. A. Esmolol B. Procainamide C. Propanolol/Metroprolol D. Verapamil - CORRECT ANSWER B. Procainamide ∙ Block sodium channels ∙ Prolong action potential duration. AIIMS MAY 2007
  7. Muscle relaxant of choice in hepatic and renal failure - A. Vecuronium B. Rapacuronium C. Cisatracurium D. Rocuronium - CORRECT ANSWER C. Cisatracurium
  8. Side effect of oxygen therapy are all except - A. Increased pulmonary compliance B. Absorption atelactasis C. Endothelial damage D. Decreased vital capacity - CORRECT ANSWER A. Increased pulmonary compliance
  9. All are seen in Malignant hyperthermia except -

A. Metabolic acidosis B. Hypertension C. Bradycardia D. Hyperkalemia - CORRECT ANSWER C. Bradycardia

  1. M.C. nerve for monitoring during anaesthesia - A. Radial nerve B. Median nerve C. Ulnar nerve D. Facial nerve - CORRECT ANSWER C. Ulnar nerve Muscle used: Adductor pollicis.
  2. All are advantages of nasotracheal intubation except - a. Good oral hygiene b. Less infection c. Less mucosal damage and bleeding d. Less movement or displacement of endotracheal tube - CORRECT ANSWER c. Less mucosal damage and bleeding AIIMS November 2007
  3. A child presented with respiratory distress was brought to emergency with bag and mask ventilation. Now the child was intubated. Chest X-ray shows right-sided deviation of mediastinum with scaphoid abdomen. His Apex- impulse has shifted to the right. What is the next step? a. Remove the endotracheal tube b. Put a nasogastric tube c. Surgery d. Tube thoracostomy - CORRECT ANSWER b. Put a nasogastric tube
  4. Regarding thiopentone all are true except - A. Contraindicated in porphyria B. Induction agent of choice in shock C. Sodium carbonate is added to improve its solubility D. Cerebro protective - CORRECT ANSWER B. Induction agent of choice in shock
  5. Mivacurium false is - A. Bronchospasm B. Flushing C. Hypertension
  1. Which one of the following agents sensitizes the myocardium to catecholamines? A. Ether B. Isoflurane C. Propofol D. Halothane - CORRECT ANSWER D. Halothane
  2. Which of the following statements is not true about etomidate? A. It precipitates coronary insufficiency B. It is an intravenous anesthetic C. It causes pain at site of injection D. It inhibits cortisol synthesis - CORRECT ANSWER A. It precipitates coronary insufficiency Note that Etomidate maintains cardiovascular stability.
  3. Which of the following anesthetic agents does not trigger malignant hyperthermia? A. Suxamethonium B. Thiopentone C. Halothane D. Isoflurane - CORRECT ANSWER B. Thiopentone
  4. Which of the following intravenous induction agents is the most suitable for day care surgery? A. Ketamine B. Morphine C. Diazepam D. Propofol - CORRECT ANSWER D. Propofol
  5. Which of the following agents is used for the treatment of postoperative shivering? A. Atropine B. Pethidine C. Thiopentone D. Suxamethonium - CORRECT ANSWER B. Pethidine
  6. Which of the following agents is not used to provide induced hypotension during surgery? A. Hydralazine B. Sodium nitroprusside C. Esmolol D. Mephentermine - CORRECT ANSWER D. Mephentermine ∙ Mephentermine is an alpha agonist which increases the blood pressure and causes tachycardia.
  7. A two-month-old infant has undergone a major surgical procedure. Regarding postoperative pain relief which one of the following is recommended:

A. Spinal narcotics via intrathecal route B. Intravenous narcotic infusion in lower dosage C. No medication is needed as infant does not feel pain after surgery due to immaturity of nervous system D. Only paracetamol suppository is adequate - CORRECT ANSWER B. Intravenous narcotic infusion in lower dosage AIIMS May 2006

  1. A 20 year old patient presented with early pregnancy for Medical Termination of Pregnancy(MTP) in day care facility.What will be the anesthetic agent of choice? A. Ketamine B. Thiopentone C. Diazepam D. Propofol - CORRECT ANSWER D. Propofol
  2. Which of the following is the neuromuscular blocking agent with the shortest onset of action? A. Rapacuronium B. Succinylcholine C. Mivacurium D. Vecuronium - CORRECT ANSWER B. Succinylcholine Shortest Non-depolarising muscle blocker is Mivacurium.
  3. Which of the following fluorinated anaesthetics corrodes metal in vaporizers and breathing systems? A. Isoflurane B. Halothane C. Sevoflurane D. Enflurane - CORRECT ANSWER B. Halothane
  4. Which of the following inhalational agents has the minimum blood gas solubility coefficient? A. Desflurane B. Sevoflurane C. Nitrous oxide D. Isoflurane - CORRECT ANSWER A. Desflurane Blood Gas Partition coefficient: Desflurane < Sevoflurane < Isoflurane < Enflurane < Halothane
  5. The following anaesthetic drug causes pain on intravenous administration -

B. Propofol C. Enflurane D. Ketamine - CORRECT ANSWER D. Ketamine Dissociative anaesthesia: ∙ Intense analgesia with only superficial sleep. ∙ EEG evidence of dissociation between thalamus and limbic system Dose: i. 2 mg/kg IV—effect within 60 sec and lasts for 5 to 8 min ii. 5 to 10 mg/kg IM—effective in 3 min and lasts for 20 to 30 min iii. 50 μg/kg/min in continuous infusion

  1. Dissociative anesthesia is associated with A. Ketamine B. Propofol C. Thiopentone D. Enflurane - CORRECT ANSWER A. Ketamine AIPG 2005
  2. Which one of the following is the fastest acting B. Sevoflurane. inhalational agent? A. Ether. B. Sevoflurane. C. Halothane. D. Isoflurane. - CORRECT ANSWER B. Sevoflurane. Here the question is asking Fastest acting. It depends upon the Blood gas partition coefficient. Desflurane < Sevoflurane < Isoflurane < Enflurane < Halothane As the BG coefficient of Desflurane is less, it has the most rapid onset of action followed by Sevoflurane.
  3. All of the following are the disadvantages of anesthetic ether,except: A. Cautery cannot be used. B. Affects blood pressure and is liable to produce arrhythmias. C. Induction is slow. D. Irritant nature of ether increases salivary and bronchial secretions. - CORRECT ANSWER B. Affects blood pressure and is liable to produce arrhythmias.

Disadvantages: Highly inflammable and highly explosive. Pungent smelling- Induction is unpleasant Increases tracheobronchial secretion Postoperative nausea and vomitting incidence are higher.

  1. Which one of the following anaesthetic agents causes a rise in the Intracranial pressure: A. Lignocaine. B. Propofol. C. Sevoflurane. D. Thiopentone sodium. - CORRECT ANSWER C. Sevoflurane.
  2. The following are used for treatment of postoperative nausea and vomiting following squint surgery in children except: A. Dexamethasone. B. Propofol. C. Ketamine. D. Ondansetron. - CORRECT ANSWER C. Ketamine.
  3. The laryngeal mask airway used for securing the airway of a patient in all of the following conditions except: A. In a child undergoing an elective/routine eye surgery. B. In a patient with a large tumour in the oral cavity. C. In a difficult intubation. D. In cardiopulmonary resuscitation. - CORRECT ANSWER B. In a patient with a large tumour in the oral cavity.
  4. The most appropriate circuit for ventilating a spontaneously breathing infant during anesthesia is A. Jackson Rees' modification of Ayres T piece B. Mapleson A or Mcgill circuit C. Maplseson C or Waters to and fro canister D. Baines circuit - CORRECT ANSWER A. Jackson Rees' modification of Ayres T piece
  5. The following modes of ventilation may be used for weaning off patients from mechanical ventilation except: A. Pressure Support Ventilation (PSV). B. Assist-Control Ventilation (ACV). C. Controlled Mechanical Ventilation (CMV). D. Synchronized Intermittent Mandatory Ventilation (SIMV). - CORRECT ANSWER C. Controlled Mechanical Ventilation (CMV).

C. Neck flexion D. Emphysema - CORRECT ANSWER C. Neck flexion 58.Which of the following device provides fixed performances oxygen therapy - A. Nasal Cannula B. Venturi mask C. O2 by T - piece D. Edinburg mask - CORRECT ANSWER B. Venturi mask

  1. Which of the following local anaesthesia is highly cardiotoxic - A. Lignocaine B. Procaine C. Mepivacaine D. Bupivacaine - CORRECT ANSWER D. Bupivacaine AIIMS November 2005
  2. Bradycardia is common after injection of - A. Midazolam B. Succinyl choline C. Dopamine D. Isoprenaline - CORRECT ANSWER B. Succinyl choline
  3. With regard to Ketamine, all of the following are true except - A. It is a direct myocardial depressent B. Emergency phenomena are more likely if anticholinergic premedication is used C. It may induced cardiac dysarythmias in patients receiving tricyclic antidepressents D. Has no effect intracranial pressure - CORRECT ANSWER D. Has no effect intracranial pressure 62.Which of the following is not a cardiovascular monitoring technique - A. transesophageal echocardiography B. Central venous pressure monitoring C. Pulmonary artery catheterization D. Capnography - CORRECT ANSWER D. Capnography
  4. Placement of a double lumen tube for lung surgery is best confirmed by - A. EtCO B. Airway pressure measurement C. Clinically by auscultation D. Bronchoscopy - CORRECT ANSWER D. Bronchoscopy
  5. The most sensitive and practical technique for detection of myocardial ischemia in the perioperative period is -

A. Magnetic Resonance Spectroscopy B. Radio labeled lactate determination C. Direct measurement of end diastolic pressure D. Regional wall of motion abnormality detected with the help of 2D transoesophealechocardiography - CORRECT ANSWER D. Regional wall motion abnormality detected with the help of 2D transesophageal echo

  1. The most common cause of hypoxia during one lung ventilation is - A. Malposition of the double lumen tube B. Increased shunt fraction C. Collapse of one lung D. Soiling of lung by secretions - CORRECT ANSWER B. Increased shunt fraction
  2. A 30 year old man with coarctation of aorta is admitted to the labour room for elective caesaream section.Which of the following is the anaesthesia technique of choice - A. Spinal anesthesia B. Epidural anesthesia C. General anesthesia D. Local anesthesia with nerve blocks - CORRECT ANSWER C. General anesthesia
  3. A 5 year old child is suffering from cyanotic heart disease.He is planned for corrective surgery.The induction agent of choice would be - A. Thiopentone B. ketamine C. Halothane D. Midazolam - CORRECT ANSWER B. ketamine
  4. While introducing swan ganz catheter, its placement in the pulmonary artery can be identified by which of the following pressure tracing A. Diastolic pressure is lower in PA than in RV B. Diastolic pressure is higher in PA than in RV C. PA pressure tracing has dicrotic notch from closure of pulmonary valve D. RV pressure tracing for plateau and sharp drop in early diastole - CORRECT ANSWER C. PA pressure tracing has dicrotic notch from closure of pulmonary valve
  5. The outcome following resuscitation of a cardiac arrest is worsened if during resuscitation patient is - A. Ringer's lactate B. Colloids C. 5% Dextrose D. Whole blood transfusion - CORRECT ANSWER C. 5% Dextrose
  6. A 6 months old child is suffering from patent ductus arteriosis(PDA) with congestive cardiac failure.Ligation of ductus arteriosus was decided for surgical management.The

D. Systemic toxicity of local anesthetics - CORRECT ANSWER D. Systemic toxicity of local anesthetics

  1. When a patient develops supraventricular tachycardia with hypotension under general anaesthesia, all of the following treatments may be instituted except: A. Direct current cardioversion B. Verapamil 5mg IV C. Carotid sinus massage D. Adenosine 3-12mg IV - CORRECT ANSWER B. Verapamil 5mg IV AIIMS May 2004
  2. The neuromuscular blocking acting of curare is brought about by A. Blocking acetylcholine synthesis B. Preventing the release of acetylcholine C. Causing persistent depolarization D. Competitive inhibition - CORRECT ANSWER D. Competitive inhibition
  3. Which of the following local anesthetics is most likely to produce an allergic reaction A. Prilocaine B. Ropivacaine C. Etidocaine D. Benzocaine - CORRECT ANSWER D. Benzocaine Ester local anesthetics are more likely to produce allergic reaction than amide local anesthetics.
  4. A 6 year old child is posted for elective urology surgery under GA. He refuses to allow the anesthesiologist an IV access. The best inhalational agent of choice for induction of anesthesia is A. Sevoflurane B. Methoxyflurane C. Desflurane D. Isoflurane - CORRECT ANSWER A. Sevoflurane
  5. A 70 year old male is posted for a surgery, which is likely to last for 4-6 hours. The best inhalational agent of choice for maintenance of anesthesia in such a case is A. Methoxyflurane B. Ether C. Trichloroethylene D. Desflurane - CORRECT ANSWER D. Desflurane
  6. A 30 year old lady is to undergo surgery under IV regional anesthesia for her left 'Trigger finger'. Which of the following should not be used in this patient

A. Lignocaine B. Bupivacaine C. Prilocaine D. Lignocaine + ketorolac - CORRECT ANSWER B. Bupivacaine Bupivacaine is not used for Bier block ( IV regional anesthesia).

  1. A 21-year old lady with a history of hypersensitivity to neostigmine is posted for an elective caesarean section under general anesthesia. The best muscle relaxant of choice in this patient should be A. Pancuronium B. Atracurium C. Rocuronium D. Vecuronium - CORRECT ANSWER B. Atracurium AIIMS November 2004
  2. A 52 year old male diagnosed as triple vessel coronary artery disease with poor left ventricular function. Coronary artery bypass grafting surgery was decided. During maintenance of anaesthesia, which one of the following agents should be preferred? A. IV Opioids B. Isoflurane C. Halothane D. Nitrous oxide - CORRECT ANSWER A. IV Opioids
  3. Which of the following produces the least damage to blood elements - A. Disc oxygenator B. Membrane oxygenator C. Bubble oxygenator D. Screen oxygenator - CORRECT ANSWER B. Membrane oxygenator
  4. Trendelenburg position produces decrease in all of the following except A. Vital capacity B. Functional residual capacity C. Compliance D. Respiratory rate - CORRECT ANSWER D. Respiratory rate
  5. Which of the following statements regarding desflurane is correct A. It causes severe myocardial depression B. It is a structural analog of isoflurane

B. Grey cylinder with white shoulders C. Black cylinders with white shoulders D. Black cylinders with grey shoulders - CORRECT ANSWER C. Black cylinders with white shoulders

  1. Interscalene approach to brachial plexus block does not provide optimal surgical anaesthesia in the area of distribution of which of the following nerve A. Ulnar B. Musculocutaneous C. Median D. Radial - CORRECT ANSWER A. Ulnar
  2. In all of the following conditions neuraxial blockade is absolutely contraindicated,except: A. Severe hypovolemia B. Pre-existing neurological deficits C. Patient refusal D. Coagulopathy - CORRECT ANSWER B. Pre-existing neurological deficits
  3. The induction agent of choice in day care anesthesia is: A. Ketamine B. Sevoflurane C. Methoxitone D. Propofol - CORRECT ANSWER D. Propofol
  4. A 30 yrs old man is posted for extraction of last molar tooth under general anaesthesia as a day care case.He wishes to resume his work after 6 hours.Which one of the following induction agents is preferred: A. Diazepam B. Propofol C. Thiopentone sodium D. Ketamine - CORRECT ANSWER B. Propofol
  5. Induction agent that may cause adrenal cortex suppression is: A. Etomidate B. Ketamine C. Thiopentione D. Propofol - CORRECT ANSWER A. Etomidate Disadvantages: Pain during injection Involuntary muscle movements Nausea/vomiting ∙∙ Adrenocortical suppression.

∙ BM supression by Nitrous oxide.

  1. During rapid sequence induction of anaesthesia: A. Pre-oxygenation is mandatory B. Sellick's maneuver is not required C. Patient is mechanically ventilated before endotracheal intubation D. Suxamethonium is contraindicated - CORRECT ANSWER A. Pre-oxygenation is mandatory
  2. At the end of a balanced anaesthesia technique with non-depolarizing muscle relaxant,a patient recovered spontaneously from the effect of muscle relaxant without any reversal.Which is the most probable relaxant the patient had received. A. Gallamine B. Pancuronium C. Vecuronium D. Atracurium - CORRECT ANSWER D. Atracurium
  3. A 15 year old boy suffering from Duchenne muscular dystrophy has to undergo tendon lengthening procedure.The most appropriate anaesthetic would be A. Induction with intravenous suxamethonim and N2O;and oxygen for maintenance B. Induction with intravenous thiopentone and N2O; and halothane for maintenance C. Inhalation induction with inhalation halothane and N2O;and oxygen for maintenance D. Induction with intravenous suxamethonim and N2O;and halothane for maintenance - CORRECT ANSWER A. Induction with intravenous suxamethonim and N2O;and oxygen for maintenance Explanation: In a boy suffering from Duchenne muscular dystrophy, there is high risk of malignant hyperthermia. ∙∙Agents causing malignant hypothermia: ∙ Inhalation agents: Halothane (Most common inhalation agent) Isoflurane Enflurane Desflurane Sevoflurane Methoxyflurane ∙ Muscle relaxants: Succinyl-choline (Most common agent) Local Anesthetics: Lignocaine