Randomized Design vs. Random Effects Model: Fixed vs. Random Effects and Implications, Exams of Statistics

This document compares the completely randomized design model with fixed and random effects, and discusses the implications of each. How to determine if an effect is fixed or random, and discusses the differences in the denominator of the f statistic, multiple comparisons, and estimating random effects for the randomized block design model.

Typology: Exams

Pre 2010

Uploaded on 08/19/2009

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Fixed effects Completely Randomized Design model
In this model,
yij =µ+τi+εij,
the tvalues of τi,τ1, τ2, ..., τt,are the only effects of interest, and εij is the
only random term, εij has a normal distribution with mean 0 and variance
σ2
e(εij N(0, σ2
e) ).
Random effects Completely Randomized Design model
In this model,
yij =µ+τi+εij,
The τiterms are now random, τiN(0 , σ2
t) , and the τiand εij are
independent.
Now the τi‘s are viewed as a random sample from a population of τi‘s,
and the ANOVA H0is H0:σ2
τ= 0 vs. Ha:σ2
τ>0 .
How do you know if an effect is fixed or random?
1. How were the levels for the factor in question chosen?
2. Is it desired to generalize the results to levels that weren’t used?
Implications for random effects
1. The denominator of the F statistic may change.
2. Generally you are not interested in doing multiple comparisons. There
may be interest in estimating σ2
τ,σ2
e, etc.
3. Estimating σ2
tmay still be of interest even if we reject H0:σ2
τβ = 0
Random effects model for Randomized Block Design
The model is:
yij =µ+τi+βj+εij,
Where τiN(0, σ2
τ), βjN(0, σ2
β), εij N(0, σ2
e),and τi,βj, and
εij are mutually independent. For the RB design (no replication) we assume
that σ2
τβ = 0.
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Fixed effects Completely Randomized Design model

In this model,

yij = μ + τi + εij , the t values of τi, τ 1 , τ 2 , ..., τt, are the only effects of interest, and εij is the only random term, εij has a normal distribution with mean 0 and variance σ^2 e (εij ∼ N (0, σ e^2 ) ).

Random effects Completely Randomized Design model

In this model,

yij = μ + τi + εij , The τi terms are now random, τi ∼ N (0 , σ^2 t ) , and the τi and εij are independent. Now the τi ‘s are viewed as a random sample from a population of τi ‘s, and the ANOVA H 0 is H 0 : σ^2 τ = 0 vs. Ha : σ τ^2 > 0.

How do you know if an effect is fixed or random?

  1. How were the levels for the factor in question chosen?
  2. Is it desired to generalize the results to levels that weren’t used?

Implications for random effects

  1. The denominator of the F statistic may change.
  2. Generally you are not interested in doing multiple comparisons. There may be interest in estimating σ^2 τ , σ^2 e , etc.
  3. Estimating σ t^2 may still be of interest even if we reject H 0 : σ τ β^2 = 0

Random effects model for Randomized Block Design

The model is:

yij = μ + τi + βj + εij , Where τi ∼ N (0, σ^2 τ ), βj ∼ N (0, σ^2 β ), εij ∼ N (0, σ^2 e ), and τi , βj , and εij are mutually independent. For the RB design (no replication) we assume that σ^2 τ β = 0.

Generalized Randomized Block Design with random effects

  1. Test H 0 : σ^2 τ β = 0 using F = MSAB/MSE
  2. If the P value for H 0 : σ τ β^2 = 0 is large ( > .15 or > .25), you may choose to pool terms, creating MSE(pooled) = (SSAB +SSE)/(dfAB + dfE), also denoted by MSRES.

Mixed Effects Models

A mixed effect model includes both fixed and random effects. The lotions for allergies experiment is an example of a mixed model. In the two factor random effect model, E(MSA) = σ^2 e +n σ^2 τ β + bn σ^2 τ , and E(MSAB) = σ^2 e +n σ^2 τ β. When H 0 : σ^2 τ = 0 is true, then E(MSA) = E(MSAB) and the sample F value is close to 1. However, E(MSE) = σ^2 e so even if the null hypothesis for factor A is true (σ^2 τ = 0) the sample F value will tend to be greater than 1 if we use F = MSA/MSE. Instead we use F = MSA/MSAB.