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Genes - Human Resource - Lecture Slides, Slides of Human Resource Management

Indian Institute of Management (IIM)Human Resource Management

Human Resource is a fundamental branch of Management Sciences. In these Lecture Slides of HRM, the Lecturer has discussed the following key concepts : Genes, Breast Cancer, Relative, Attributable, Tailored, Therapy, Farmer, Nature, Risk, Cancer Genes

Typology: Slides

2012/2013

Uploaded on 07/25/2013

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Breast Cancer Genes - GWAS Genes
Risk
Allele
Freq Relative
Risk
Pop.
Attributable
Risk
CASP8 0.86 1.13 20%
FGFR2 0.38 1.26 19%
TNRC9 0.25 1.20 10%
“2q” 0.58 1.20 7%
Gene
Adapted from Pharoah P et al. N Engl J Med 2008;358:2796-2803
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Breast Cancer Genes - GWAS Genes

Risk Allele Freq

Relative Risk

Pop. Attributable Risk

CASP8 0.86 1.13 20%

FGFR2 0.38 1.26 19%

TNRC9 0.25 1.20 10%

“2q” 0.58 1.20 7%

Gene

Adapted from Pharoah P et al. N Engl J Med 2008;358:2796-2803Docsity.com

Bryant et al., Nature, 434: 913, 2005 Farmer et al.,^ Nature,^ 434: 917, 2005

Tailored therapy?

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