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Genetic Code - Biochemistry - Lecture Notes, Study notes of Biochemistry

Genetic Code, Understand Degeneracy in Genetic Code, How Many Possible Codons?, Know Stop Codons and Start Codon, Understand What is Meant by Codon Usage and Possible Significance, Wobble in Trna Anticodon, Understand Significance of Wobble, Understand types of Suppressors, Understand How two Frameshift Mutations can Work as Intragenic Suppressor, Understand How Trna Nonsense Suppressors Work are terms and points of this lecture. There are plenty of lecture notes of Biochemistry available in my

Typology: Study notes

2011/2012

Uploaded on 11/20/2012

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BICH/GENE 431 KNOWLEDGE OBJECTIVES
Chapter 15 – Genetic Code
Understand degeneracy in genetic code
How many possible codons?
Know stop codons and start codon(s)
Understand what is meant by codon usage and possible significance
Wobble in tRNA anticodon : codon basepairing in 3rd position of codon
Understand significance of wobble – fewer tRNAs necessary to decode
Know wobble rules for basepairing (Table 15-2)
Know differences between missense, nonsense, frameshift mutations
Understand types of suppressors – reversion, second-site suppressors (intragenic vs.
intergenic)
Understand how two frameshift mutations can work as intragenic suppressor
Understand how tRNA nonsense suppressors work (good example of intergenic)
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BICH/GENE 431 KNOWLEDGE OBJECTIVES

Chapter 15 – Genetic Code Understand degeneracy in genetic code How many possible codons? Know stop codons and start codon(s) Understand what is meant by codon usage and possible significance Wobble in tRNA anticodon : codon basepairing in 3 rd^ position of codon Understand significance of wobble – fewer tRNAs necessary to decode Know wobble rules for basepairing (Table 15-2) Know differences between missense, nonsense, frameshift mutations Understand types of suppressors – reversion, second-site suppressors (intragenic vs. intergenic) Understand how two frameshift mutations can work as intragenic suppressor Understand how tRNA nonsense suppressors work (good example of intergenic)

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