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Genetic variation can be introduced in many ways, such as:
Meiosis produces 4 haploid daughter cells that are genetically different to each other (unique). There are 2 nuclear divisions- 4 haploid daughter cells from 1 parent cell. In the first division (meiosis I) - homologous chromosomes are separated - these are the pair of chromosomes you inherit - one from each parent - they are the same type of chromosome - same gene but may be different versions of the gene - same gene loci. In the second division (meiosis II) - the sister chromatids of each chromosomes are separated First division - homologous chromosomes separate Second division - sister chromatids separate You do not need to know about PMAT here, only about how genetic variation is introduced! ( phew… ) There are 2 main mechanisms through which this occurs (both occur in meiosis I):
In meiosis I, homologous pairs of chromosomes line up opposite to each other at the equator of the cell. Which side of the equator the paternal and maternal chromosomes line up is random however homologous pairs are next to each other. These pairs are separated so that one of each homologous pair ends up in the the daughter cell - each daughter cell is genetically unique Different combinations of maternal paternal chromosomes so a mix of different alleles for different genes 2^n → where n is the number of homologous pairs. This is used to calculate the number of possible combinations of chromosomes in the daughter cell produced Square this number to find the amount of combinations when male and female gametes combine
This introduced further genetic variation.
YOU MUST look for a diploid parent cell dividing to become a haploid daughter cell (2n → n) It may not always be the formation of gametes -different organisms have different processes.
Gene mutations involve a change in the base sequence of the DNA in chromosomes - these randomly occur during DNA REPLICATION. They include base deletion or base substitution (later on you will learn more but for AS and paper 1 this is enough) Random mutations are more likely to occur if there has been an exposure to mutagenic agents: