Genetics Chapter 3 - Exam 1., Exams of Genetics

Genetics Chapter 3 - Exam 1. Genetics Chapter 3 - Exam 1.

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2023/2024

Available from 06/28/2024

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Genetics Chapter 3 - Exam 1
chance deviation -
Chi Square Test - Chance events subject to random fluctuations
Expected outcome is diminished by larger sample size
chi test -
a statistical test to determine whether or not an observed set of data is equivalent to the
expected data
chromosome theory of inheritance -
A basic principle in biology stating that genes are located on chromosomes and that the
behavior of chromosomes during meiosis accounts for inheritance patterns. -- Boveri and Sutton
dizygotic twins -
often called fraternal twins, occurring when two eggs each get fertilized by two different
sperm, resulting in two zygotes in the uterus at the same time
locus -
Location of a gene on a chromosome
null hypothesis -
the hypothesis that there is no significant difference between observed and expected datasets
pedigree -
A diagram that shows the occurrence of a genetic trait in several generations of a family.
proband -
in genetics research, the individual displaying the trait or characteristic being studied,
leading to the construction of a pedigree to track the trait
product law -
the probability of two independent random events both occurring is the product of the
individual probabilities of the events -- the AND rule
reciprocal cross -
a cross in which the phenotypes of the male and female are reversed compared with a prior
cross
rescue experiment -
An experimental approach that involves transferring a gene or protein to cells of an organism
to restore a particular phenotype or function.
selfing -
self-fertilization in plants
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Genetics Chapter 3 - Exam 1

chance deviation - Chi Square Test - Chance events subject to random fluctuations Expected outcome is diminished by larger sample size chi test - a statistical test to determine whether or not an observed set of data is equivalent to the expected data chromosome theory of inheritance - A basic principle in biology stating that genes are located on chromosomes and that the behavior of chromosomes during meiosis accounts for inheritance patterns. -- Boveri and Sutton dizygotic twins - often called fraternal twins, occurring when two eggs each get fertilized by two different sperm, resulting in two zygotes in the uterus at the same time locus - Location of a gene on a chromosome null hypothesis - the hypothesis that there is no significant difference between observed and expected datasets pedigree - A diagram that shows the occurrence of a genetic trait in several generations of a family. proband - in genetics research, the individual displaying the trait or characteristic being studied, leading to the construction of a pedigree to track the trait product law - the probability of two independent random events both occurring is the product of the individual probabilities of the events -- the AND rule reciprocal cross - a cross in which the phenotypes of the male and female are reversed compared with a prior cross rescue experiment - An experimental approach that involves transferring a gene or protein to cells of an organism to restore a particular phenotype or function. selfing - self-fertilization in plants

sum law - the probability of obtaining any single outcome, where that outcome can be achieved by two or more events, is equal to the sum of the individual probabilities of all such events -- the OR rule testcross - The result of breeding a recessive homozygote with an organism of dominant phenotype but unknown genotype. transmission genetics - The branch of genetics concerned with the mechanisms by which genes are transferred from parent to offspring. Which of Mendel's postulates can only be demonstrated in crosses involving at least two pairs of traits? State the postulate. a) segregation b) recessiveness/dominance c) independent assortment d)unit factor in pairs - c) independent assortment Thalassemia is an inherited anemic disorder in humans. Affected individuals exhibit either a minor anemia or a major anemia. Assuming that only a single gene pair and two alleles are involved in the inheritance of these conditions, is thalassemia a dominant or recessive disorder? - incomplete dominance, because the trait (anemia has scales); Heterozygous for the trait is minor anemia, while homozygous dominant for the trait i major anemia Chi-square analysis - assesses how closely the observed frequencies fit the pattern of the expected frequencies and is referred to as a "goodness-of-fit" test if p< 0.05 reject null hypothesis if p> 0.05 accept null hypothesis

  • degrees of freedom = n- The researcher can set more or less stringent standards by deciding to raise or lower the p value used to reject or not reject the hypothesis. In the case of the chi-square analysis of genetic crosses, would the use of a standard of p = 0.10 be more or less stringent about not rejecting the null hypothesis? Explain - as the standard p value increases, less difference between the observed and the expected data is required to reject the null hypothesis that the observed date fit the expected. As p value increases in the normal standard (p< 0.05), the more significant is the difference between expected and observed data autosomal dominant pedigree - appear in every generation; males and females are equally affected; all affected individuals have an affected parent; most affected individuals are heterozygous autosomal recessive pedigree - skip generations; males and females are equally affected; all affected individuals are homozygous recessive; unaffected parent of affected offspring are obligate heterozygous; occur more often in consanguineous mating