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A detailed overview of various gestational conditions that can occur during pregnancy, including hyperemesis gravidarum, pregnancy induced hypertension, gestational diabetes, rh incompatibility, iron deficiency anemia, folic acid deficiency anemia, and sickle cell anemia. It covers the predisposing factors, manifestations, therapeutic management, and potential complications associated with each condition. The comprehensive nature of the document makes it a valuable resource for healthcare professionals, students, and individuals interested in understanding the complexities of maternal health during pregnancy.
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Hyperemesis Gravidarum
Na restriction for severe pre-eclampsia and eclampsia Monitor VS, FHT, and I&O Obtain daily weights Hydrazaline Hypotensive agent-vasodilator MgSo4 Drug of choice
Therapeutic management: Insulin Started if DIET alon is unsuccessful Regular insulin (short acting) combined w/ intermediate type BID before breakfast and dinner (instruct to EAT immediately after injections) Oral hypoglycemia agents (OHA)- not recommended in pregnancy as it crosses the placenta- TERATOGEN Teach on proper insulin injection Monitor blood glucose level RH INCOMPATIBILITY Occurs when an Rh(-) mother bars an Rh(+) fetus If the father is homozygous(DD), fetus is 100% Rh(+) If the father is heterozygous (Dd), fetus is 50% Rh(+)/RH(-) Assessment: Anti-D antibody titer(Coomb’s test) 0 - Normal, no antibodies(first pregnancy) 1:8-minimal antibodies, not enough to cause hemolysis 1:16-Rh sensitization(another test- spectrophotometry) Spectrophotometry- measure amniotic fluid density=birumin level) Zone 1 - no distress Zone 3-minimal distress Zone 3 - high fluid density Rh(-) women(commercial prep of Rhlg is administered at 28wks of pregnancy and 72hrs after birth Prevents the formation of natural anti bodies IRON DIFICIENCY ANEMIA Most common anemia during pregnancy Microcytic/hypochromic Predisposing fx: Low iron diet Short birth Assessment/manifestations: CBC Decreased hemoglobin, hematocrit, serum ferritin Pallor, fatigue, dizziness Pica - unusual craving for food Complication: Pre-term birth(d/t poor placental perfusion) Therapeutic management: DIET modifications Iron rich food Prophylactic mngmnt Therapeutic medications Folic Acid Deficiency Anemia MEGALOBLASTIC Predisposing fx: Multiple gestation Post gastric bypass surgery Women taking hydantoin
Complications: Early miscarriage/spontaneous abortion Abruptio placenta Assessment: CBC Mean corpuscular volume (MCV) elevated Therapeutic management: DIET modification-folic acid rich foods Folic acid supplement-600mcg daily beginning of pregnancy multi pregnancy 400mcg ecpecting to be pregnant Sickle Cell Anemia RBC becomes crescent shape that may cause clogging in blood vessels and can lead to poor O2 perfusion to organs Factors that lead to SICKLING: Elevated temperature Dehydration Low O2 tension Assessment: Hemoglobin- 6 - 8mg/dL 5 - 6 during sickle crisis CBC-sickled RBC Therapeutic management: Maintain hydration Dietary modification(high iron/folic acid) Elevate legs when resting Monitor fetal health Decrease O2 demand Periodic exchange transfusion Hypotonic fluid administration Method of delivery is individualized