Name: ________________________
Date: ______________ Per: _______
Bi logy DNA
Reading: Telomeres
Read the article Double Trouble at Chromosome Ends found in the Science Daily online journal (published
February 28, 2024; sourced from Rockefeller University).
https://www.sciencedaily.com/releases/2024/02/240228115250.htm
Answer the following questions from the article:
1. What is the job of the telomeres?
2. What is the “end-replication problem”?
3. What does the enzyme telomerase do?
4. What can nucleases do?
5. On which strand does telomerase work?
6. What enzyme fixes the telomeres on the other strand (compared to your answer in #5)?
7. What causes the disorder Coats plus syndrome?
What are the symptoms of this syndrome?
Protect the end of the chromosomes
The telomeres arent growing shorter each round
It adds the telomeric then repeats to the end of the chromosomes
Nucleases are DNA replicating enzymes
The 3' End
Telomerase
Mutations in CST-Pola Primase
- Eye disorder
- Abnormalities in the brain
- Bones
- Gi tract
