Headspace Gas Analysis for Pharmaceutical
Packaging
The purpose of CD Formulation's headspace analysis tests for pharmaceutical
packaging is to detect the residual gas content in pharmaceutical packaging and to
adjust the packaging process accordingly. The residual gases inside the package
should not be disregarded at the end of the packaging process. It is very difficult to
control and change the gas content inside the package from the end of filling until the
product is opened and used. The use of barrier packaging materials can only prevent
the gas from entering/leaking out of the packaging material, but cannot eliminate the
oxygen and other gases already inside the package (excluding the case of adding
deaeration technology to the package). If the content of residual gas exceeds the
maximum concentration required for product preservation, no matter how good the
high barrier material and how well sealed packaging form can not meet the shelf-life
requirements of the product. Therefore, it is necessary to detect the residual gas
content in the package and adjust the packaging process accordingly.
Our Services
Residual gases as well as product adsorbed gases can be obtained by testing the
headspace of the packaging-detecting the gas composition gathered at the top of the
packaging-only with a difference in detection time. If residual gases are to be
detected, this should be done immediately after the end of the packaging process;
however, if product adsorbed gases are to be detected, this should be done after the
