Study with the several resources on Docsity
Earn points by helping other students or get them with a premium plan
Prepare for your exams
Study with the several resources on Docsity
Earn points to download
Earn points by helping other students or get them with a premium plan
An in-depth analysis of various hematological disorders, with a focus on microcytic anemia. It covers the characteristics, causes, and symptoms of microcytic anemia, including its subtypes like thalassemia and sickle cell anemia. The document also discusses other related disorders such as iron deficiency anemia, anemia of chronic disease, and hereditary spherocytosis. It offers insights into the pathophysiology, lab values, and treatment options for these conditions.
Typology: Quizzes
1 / 15
This page cannot be seen from the preview
Don't miss anything!
Which of the following is considered a microcytic anemia? Folate deficiency. Hereditary spherocytosis. B deficiency. Iron deficiency. Which of the following is not a clinical characteristic of anemia? Pallor Bradycardia Fatigue Dyspnea The terms normocytic, microcytic, and macrocytic characterizes red blood cells by their Size
Which of the following would normocytic-normochromic indicate? The cell is normal in size and normal in hemoglobin level The cell is normal in size, but low in hemoglobin level The cell is abnormal in shape, but normal in hemoglobin level The cell is abnormal in size and abnormal in hemoglobin level Which of the following symptoms reflect decreased tissue oxygenation as an effect of anemia? Symptoms of Decreased Tissue Oxygenation Dizziness, dyspnea, & weakness Which of the following is a type of macrocytic anemia? Thalassemia. Anemia of chronic disease. Vitamin B- deficiency. Iron-deficiency anemia. Which of the following would indicate that the patient’s iron stores are depleted? Ferritin level. Total iron binding capacity. Vitamin-B- level. Total RBC count. The most common type of anemia is Iron deficiency anemia
Increased absorption of iron-containing foods. Excessive bleeding. Reduced absorption of Vitamin B-12. The treatment of iron deficiency anemia includes: Blood transfusions. Vitamin-B- replacement. Ferritin replacement. Iron supplementation.
As you should recall, microcytic anemias result from conditions whereby the RBCs are small (MCV<80 dL). These anemias can also be classified according to their color, or amount of hemoglobin per RBC (MCHC). Identify if each item below is Microcytic Hypochromic, Microcytic Normochromic, or Microcytic Hyperchromic. Thalassemia Hereditary spherocytosis Sideroblastic Iron deficiency Anemia of inflammation and chronic disease Microcytic Hyperchromic Microcytic Normochromic Microcytic Hypochromic
The basic pathophysiology of iron deficiency anemia is that there are insufficient iron levels or the inability of the cell’s mitochondria to utilize iron effectively. True False Which of the following are iron-rich foods? Meat. Lima beans. Spinach. When iron stores are depleted, the cell’s mitochondria are still able to utilize iron effectively due to compensatory mechanisms. True False A transferrin deficiency will most likely result in: Pernicious anemia. Hemolytic anemia. Aplastic anemia. Iron-deficiency anemia. One of the common precipitating factors of folate deficiency is alcohol abuse. True False Folic acid is essential to the body because it: Plays a major role in the maturing of
Prevents cardiovascular disease. Impacts the absorption of vitamin B-12. A non-megaloblastic anemia would be caused by liver disease A deficiency of intrinsic factor will result in pernicious anemia The MCV lab values will be normal in a patient with pernicious anemia Which of the following lab values are normal for the patient with folate deficiency? Reticulocyte count. MCV. Folate. Ferritin. Which of the following will be elevated in a patient with pernicious anemia? Serum B-12. Folate. Reticulocyte count. MCV. Which of the following lab values will be low in a patient with folate deficiency? MCV. MCHC. Ferritin. Reticulocyte count.
An individual who has received an incorrect blood transfusion will exhibit signs of:
Post-hemorrhagic anemia Hemolytic anemia
Reticulocyte count MCHC is normal in all the above anemias The lab values are low in aplastic anemia. lab values are normal for hemolytic anemia. Which of the following statements are correct regarding thalassemia? Is characterized by acute and painful episodes. May have many possible genetic mutations. Maintains effective erythropoiesis. Involves a double amino acid change on the beta chain. The patient with sickle cell anemia is at high risk for stroke. True False The pathophysiology of sickle cell anemia involves a single amino- acid change on the beta-chain. True False There are four genes involved in encoding synthesis of the alpha protein chains for Hb and are located on chromosome number 16. True False Cells that contain abnormal types of hemoglobin are more susceptible to infection by the parasite that causes malaria True MCV
Sickle Cell Anemia Thalassemia Involves a single amino acid change on the beta-chain Increased red blood cell (RBC) hemoglobin S concentration, RBC dehydration, acidosis, and hypoxemia May have many possible genetic mutations Characterized by acute painful episodes Ineffective erythropoiesis Occurs primarily in persons from southeast Asia and China
The patient with thalassemia is at high risk for stroke. True False Sickle-cell anemia is an: Idiopathic in blood disorder. Autosomal dominant genetic
disorder. Autosomal recessive genetic disorder. Immunodeficiency disorder.
